Electrochemical microfluidic sensing platforms for biosecurity analysis.

Biosecurity encompasses the health and safety of humans, animals, plants, and the environment. In this article, "biosecurity" is defined as encompassing the comprehensive aspects of human, animal, plant, and environmental safety. Reliable biosecurity testing technology is the key point for effectively assessing biosecurity risks and ensuring biosecurity. Therefore, it is crucial to develop excellent detection technologies to detect risk factors that can affect biosecurity. An electrochemical microfluidic biosensing platform integrates fluid control, target recognition, signal transduction, and output and incorporates the advantages of electrochemical analysis technology and microfluidic technology. Thus, an electrochemical microfluidic biosensing platform, characterized by exceptional analytical sensitivity, portability, rapid analysis speed, low reagent consumption, and low risk of contamination, shows considerable promise for biosecurity detection compared to traditional, more complex, and time-consuming detection technologies. This review provides a concise introduction to electrochemical microfluidic biosensors and biosecurity. It highlights recent research advances in utilizing electrochemical microfluidic biosensing platforms to assess biosecurity risk factors. It includes the use of electrochemical microfluidic biosensors for the detection of risk factors directly endangering biosecurity (direct application: namely, risk factors directly endangering the health of human, animals, and plants) and for the detection of risk factors indirectly endangering biosecurity (indirect application: namely, risk factors endangering the safety of food and the environment). Finally, we outline the current challenges and future perspectives of electrochemical microfluidic biosensing platforms.