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American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation

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https://www.readbyqxmd.com/read/29031857/defining-renal-neoplastic-disease-one-cell-at-a-time-mass-cytometry-a-new-tool-for-the-study-of-kidney-biology%C3%A2-and%C3%A2-disease
#1
EDITORIAL
Peter J Nelson, Matthias Kretzler
No abstract text is available yet for this article.
October 11, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28985981/in-reply-to-idarucizumab-dosing-in-kidney-failure
#2
LETTER
James E Novak, Khalid Alamiri, Jerry Yee
No abstract text is available yet for this article.
October 3, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28985980/idarucizumab-dosing-in-kidney-failure
#3
LETTER
Luke Yip, Jou-Fang Deng
No abstract text is available yet for this article.
October 3, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29029808/potassium-homeostasis-in-health-and-disease-a-scientific-workshop-cosponsored-by-the-national-kidney-foundation-and-the-american-society-of-hypertension
#4
Csaba P Kovesdy, Lawrence J Appel, Morgan E Grams, Lisa Gutekunst, Peter A McCullough, Biff F Palmer, Bertram Pitt, Dominic A Sica, Raymond R Townsend
While much emphasis, and some controversy, centers on recommendations for sodium intake, there has been considerably less interest in recommendations for dietary potassium intake, in both the general population and patients with medical conditions, particularly acute and chronic kidney disease. Physiology literature and cohort studies have noted that the relative balance in sodium and potassium intakes is an important determinant of many of the sodium-related outcomes. A noteworthy characteristic of potassium in clinical medicine is the extreme concern shared by many practitioners when confronted by a patient with hyperkalemia...
September 29, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28941764/kdoqi-us-commentary-on-the-2017-kdigo-clinical-practice-guideline-update-for-the-diagnosis-evaluation-prevention-and%C3%A2-treatment-of-chronic-kidney-disease-mineral-and-bone%C3%A2-disorder-ckd-mbd
#5
Tamara Isakova, Thomas L Nickolas, Michelle Denburg, Sri Yarlagadda, Daniel E Weiner, Orlando M Gutiérrez, Vinod Bansal, Sylvia E Rosas, Sagar Nigwekar, Jerry Yee, Holly Kramer
Chronic kidney disease-mineral and bone disorder (CKD-MBD) encompasses laboratory and bone abnormalities and vascular calcification and has deleterious effects on clinical outcomes. KDOQI (Kidney Disease Outcomes Quality Initiative), an initiative of the National Kidney Foundation, addressed this issue with the publication of a clinical practice guideline for bone metabolism and disease in CKD in 2003, and 2 years later, a new definition and classification scheme for CKD-MBD was developed following a KDIGO (Kidney Disease: Improving Global Outcomes) Controversies Conference...
September 20, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28941763/oral-anticoagulants-to-prevent-stroke-in-nonvalvular-atrial-fibrillation-in-patients-with-ckd-stage-5d-an-nkf-kdoqi-controversies-report
#6
Vinod K Bansal, Charles A Herzog, Mark J Sarnak, Michael J Choi, Ravindra Mehta, Bernard G Jaar, Michael V Rocco, Holly Kramer
Stroke risk may be more than 3-fold higher among patients with chronic kidney disease stage 5D (CKD-5D) compared to the general population, with the highest stroke rates noted among those 85 years and older. Atrial fibrillation (AF), a strong risk factor for stroke, is the most common arrhythmia and affects >7% of the population with CKD-5D. Warfarin use is widely acknowledged as an important intervention for stroke prevention with nonvalvular AF in the general population. However, use of oral anticoagulants for stroke prevention in patients with CKD-5D and nonvalvular AF continues to be debated by the nephrology community...
September 20, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28912055/data-without-numbers
#7
EDITORIAL
Amar D Bansal
No abstract text is available yet for this article.
September 11, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28912054/effectiveness-of-pharmacist-interventions-on-cardiovascular-risk-in-patients-with-ckd-a-subgroup-analysis-of-the-randomized-controlled-rxeach-trial
#8
Yazid N Al Hamarneh, Ross T Tsuyuki, Charlotte A Jones, Braden Manns, Marcello Tonelli, Nairne Scott-Douglass, Kailash Jindal, Wendy Tink, Brenda R Hemmelgarn
BACKGROUND: Affecting a substantial proportion of adults, chronic kidney disease (CKD) is considered a major risk factor for cardiovascular (CV) events. It has been reported that patients with CKD are underserved when it comes to CV risk reduction efforts. STUDY DESIGN: Prespecified subgroup analysis of a randomized controlled trial. SETTING & PARTICIPANTS: Adults with CKD and at least 1 uncontrolled CV risk factor were enrolled from 56 pharmacies across Alberta, Canada...
September 11, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28912053/erratum-regarding-food-insecurity-ckd-and-subsequent-esrd-in-us-adults-am-j-kidney-dis-2017-70-1-38-47
#9
(no author information available yet)
No abstract text is available yet for this article.
September 11, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28899602/an-increasingly-complex-relationship-between-salt-and-water
#10
EDITORIAL
Evan C Ray, Thomas R Kleyman
No abstract text is available yet for this article.
September 9, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28899601/baclofen-toxicity-in-kidney-disease
#11
Erin Wolf, Niraj R Kothari, John K Roberts, Matthew A Sparks
Baclofen, a commonly prescribed muscle relaxant, is primarily excreted via the kidneys; toxicity is a potentially serious adverse outcome in patients with decreased kidney function. We describe a patient with end-stage kidney disease receiving hemodialysis who developed neurotoxicity and hemodynamic instability after receiving baclofen for muscle spasms. In this case, prompt recognition of baclofen toxicity and urgent hemodialysis were effective in reversing this toxicity. This case is used to examine the pharmacokinetics and pathophysiology of baclofen toxicity and discuss appropriate diagnosis and management of baclofen toxicity...
September 9, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28870376/associations-of-body-mass-index-and-body-fat-with-markers%C3%A2-of%C3%A2-inflammation-and-nutrition-among-patients-receiving%C3%A2-hemodialysis
#12
Cynthia Delgado, Glenn M Chertow, George A Kaysen, Lorien S Dalrymple, John Kornak, Barbara Grimes, Kirsten L Johansen
BACKGROUND: Understanding the extent to which visceral and subcutaneous body fat are associated with markers of nutrition and inflammation in patients on dialysis therapy could shed light on the obesity paradox and the biology of subcutaneous fat. STUDY DESIGN: Cross-sectional. SETTING & PARTICIPANTS: 609 adults receiving hemodialysis who participated in the ACTIVE/ADIPOSE Study. PREDICTORS: Body mass index (BMI), waist circumference, and bioelectrical impedance spectroscopy-derived estimates of percent body fat...
September 1, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28844586/performance-of-serum-creatinine-and-kidney-injury-biomarkers-for-diagnosing-histologic-acute-tubular-injury
#13
Dennis G Moledina, Isaac E Hall, Heather Thiessen-Philbrook, Peter P Reese, Francis L Weng, Bernd Schröppel, Mona D Doshi, F Perry Wilson, Steven G Coca, Chirag R Parikh
BACKGROUND: The diagnosis of acute kidney injury (AKI), which is currently defined as an increase in serum creatinine (Scr) concentration, provides little information on the condition's actual cause. To improve phenotyping of AKI, many urinary biomarkers of tubular injury are being investigated. Because AKI cases are not frequently biopsied, the diagnostic accuracy of concentrations of Scr and urinary biomarkers for histologic acute tubular injury is unknown. STUDY DESIGN: Cross-sectional analysis from multicenter prospective cohort...
August 23, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28844585/arsenic-exposure-from-drinking-water-and-the-incidence-of-ckd-in-low-to-moderate-exposed-areas-of-taiwan-a-14-year-prospective-study
#14
Ling-I Hsu, Fang-I Hsieh, Yuan-Hung Wang, Tai-Shuan Lai, Meei-Maan Wu, Chien-Jen Chen, Hung-Yi Chiou, Kuang-Hung Hsu
BACKGROUND: Arsenic exposure is associated with decreased kidney function. The association between low to moderate arsenic exposure and kidney disease has not been fully clarified. STUDY DESIGN: The association between arsenic exposure from drinking water and chronic kidney disease (CKD) was examined in a long-term prospective observational study. SETTING & PARTICIPANTS: 6,093 participants 40 years and older were recruited from arseniasis-endemic areas in northeastern Taiwan...
August 23, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28838767/c4-nephritic-factors-in-c3-glomerulopathy-a-case-series
#15
Yuzhou Zhang, Nicole C Meyer, Fernando C Fervenza, Winnie Lau, Adam Keenan, Gabriel Cara-Fuentes, Dingwu Shao, Aalia Akber, Veronique Fremeaux-Bacchi, Sanjeev Sethi, Carla M Nester, Richard J H Smith
BACKGROUND: C3 glomerulopathy (C3G) defines a group of rare complement-mediated kidney diseases with a shared underlying pathophysiology: dysregulation of complement in the fluid phase and glomerular microenvironment. Dysregulation can be driven by autoantibodies to C3 and C5 convertases. STUDY DESIGN: Case series. SETTING & PARTICIPANTS: 168 patients with C3G (dense deposit disease, 68; C3 glumerulonephritis, 100) selected from our C3G biobank...
August 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28838766/concentrations-of-trace-elements-in-hemodialysis-patients-a%C3%A2-prospective-cohort-study
#16
Marcello Tonelli, Natasha Wiebe, Aminu Bello, Catherine J Field, John S Gill, Brenda R Hemmelgarn, Daniel T Holmes, Kailash Jindal, Scott W Klarenbach, Braden J Manns, Ravi Thadhani, David Kinniburgh
BACKGROUND: Low concentrations and excessive concentrations of trace elements have been commonly reported in hemodialysis patients, but available studies have several important limitations. STUDY DESIGN: Random sample of patients drawn from a prospective cohort. SETTING & PARTICIPANTS: 198 incident hemodialysis patients treated in 3 Canadian centers. MEASUREMENTS: We used mass spectrometry to measure plasma concentrations of the 25 elements at baseline, 6 months, 1 year, and 2 years following enrollment in the cohort...
August 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28838765/adherence-to-the-mediterranean-dietary-pattern-and-incidence-of-nephrolithiasis-in-the-seguimiento-universidad-de-navarra-follow-up-sun-cohort
#17
Alessandro Leone, Alejandro Fernández-Montero, Carmen de la Fuente-Arrillaga, Miguel Ángel Martínez-González, Simona Bertoli, Alberto Battezzati, Maira Bes-Rastrollo
BACKGROUND: Diet plays an important role in the pathogenesis of nephrolithiasis. Limited data are available to investigate the association between a Mediterranean dietary pattern and risk for nephrolithiasis. STUDY DESIGN: Prospective cohort study. SETTING & PARTICIPANTS: 16,094 men and women without a history of nephrolithiasis who participated in the Seguimiento Universidad de Navarra Follow-up (SUN) Project. PREDICTORS: A validated 136-item food frequency questionnaire was used to assess baseline adherence to a Mediterranean dietary pattern that is high in fruits, vegetables, nuts, fish, and legumes, but moderate in alcohol and low in meats, saturated fats, and sugars...
August 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28838764/prenatal-growth-and-ckd-in-older-adults-longitudinal-findings-from-the-helsinki-birth-cohort-study-1924-1944
#18
Johan G Eriksson, Minna K Salonen, Eero Kajantie, Clive Osmond
BACKGROUND: According to the Developmental Origins of Health and Disease (DOHaD) hypothesis, several noncommunicable diseases, including hypertension, type 2 diabetes, and coronary heart disease, have their origins in early life. Chronic kidney disease (CKD) has traditionally been assumed to develop as the result of an interaction between genetic and environmental factors, although more recently, the importance of factors present early in life has been recognized. STUDY DESIGN: Longitudinal birth cohort study...
August 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28823586/association-between-sonographically-diagnosed-nephrolithiasis-and-subclinical-coronary-artery-calcification%C3%A2-in%C3%A2-adults
#19
Seolhye Kim, Yoosoo Chang, Eunju Sung, Jeong Gyu Kang, Kyung Eun Yun, Hyun-Suk Jung, Young Youl Hyun, Kyu-Beck Lee, Kwan Joong Joo, Hocheol Shin, Seungho Ryu
BACKGROUND: Although recent studies suggest an association between nephrolithiasis and clinical cardiovascular events, this association has been underexplored. STUDY DESIGN: Cross-sectional study. SETTING & PARTICIPANTS: 62,091 asymptomatic adults without known coronary heart disease who underwent a screening health examination that included cardiac tomography. PREDICTOR: Nephrolithiasis. OUTCOME: Coronary artery calcification (CAC)...
August 17, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28823585/risk-of-venous-thromboembolism-in-patients-by-albuminuria-and-estimated-gfr
#20
David Massicotte-Azarniouch, Anan Bader Eddeen, Alejandro LazoLanger, Amber O Molnar, Ngan N Lam, Megan K McCallum, Sarah Bota, Deborah Zimmerman, Amit X Garg, Ziv Harel, Jeffery Perl, Ron Wald, Manish M Sood
BACKGROUND: The risk for venous thromboembolism (VTE) is elevated with albuminuria or a low estimated glomerular filtration rate (eGFR). However, the VTE risk due to the combined effects of eGFR and albuminuria are unknown. STUDY DESIGN: Population-based cohort study. SETTINGS & PARTICIPANTS: 694,956 adults in Ontario, Canada, from 2002 to 2012. FACTORS: eGFR and albumin-creatinine ratio (ACR). OUTCOME: VTE...
August 17, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
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