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American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation

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https://www.readbyqxmd.com/read/29784617/evolution-of-echocardiographic-measures-of-cardiac-disease-from-ckd-to-esrd-and-risk-of-all-cause-mortality-findings-from-the-cric-study
#1
Nisha Bansal, Jason Roy, Hsiang-Yu Chen, Rajat Deo, Mirela Dobre, Michael J Fischer, Elyse Foster, Alan S Go, Jiang He, Martin G Keane, John W Kusek, Emile Mohler, Sankar D Navaneethan, Mahboob Rahman, Chi-Yuan Hsu
RATIONALE & OBJECTIVE: Abnormal cardiac structure and function are common in chronic kidney disease (CKD) and end-stage renal disease (ESRD) and linked with mortality and heart failure. We examined changes in echocardiographic measures during the transition from CKD to ESRD and their associations with post-ESRD mortality. STUDY DESIGN: Prospective study. SETTING & PARTICIPANTS: We studied 417 participants with CKD in the Chronic Renal Insufficiency Cohort (CRIC) who had research echocardiograms during CKD and ESRD...
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29784616/seizures-antiepileptic-drugs-and-ckd
#2
REVIEW
Victoria Títoff, Heather N Moury, Igor B Títoff, Kevin M Kelly
There are 2 major categories of patients with seizures and chronic kidney disease (CKD): patients who develop acute symptomatic seizures in the setting of CKD and patients with epilepsy who at some point develop CKD. The incidence of uremic seizures with kidney failure is ∼10%. These seizures are often nonconvulsive and may mimic uremic encephalopathy. Recognition and management of such situations may be challenging for treating physicians who are non-neurologists. Furthermore, practitioners caring for patients with seizures with or without an established diagnosis of epilepsy in the setting of CKD frequently encounter challenges in the selection, loading, titration, and maintenance of antiepileptic drugs (AEDs) due to potentially altered pharmacokinetics of the AEDs...
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29784615/autosomal-dominant-tubulointerstitial-kidney-disease-clinical-presentation-of-patients-with-adtkd-umod-and-adtkd-muc1
#3
Nadia Ayasreh, Gemma Bullich, Rosa Miquel, Mónica Furlano, Patricia Ruiz, Laura Lorente, Oliver Valero, Miguel Angel García-González, Nisrine Arhda, Intza Garin, Víctor Martínez, Vanessa Pérez-Gómez, Xavier Fulladosa, David Arroyo, Alberto Martínez-Vea, Mario Espinosa, Jose Ballarín, Elisabet Ars, Roser Torra
RATIONALE & OBJECTIVE: Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a rare underdiagnosed cause of end-stage renal disease (ESRD). ADTKD is caused by mutations in at least 4 different genes: MUC1, UMOD, HNF1B, and REN. STUDY DESIGN: Retrospective cohort study. SETTING & PARTICIPANTS: 56 families (131 affected individuals) with ADTKD referred from different Spanish hospitals. Clinical, laboratory, radiologic, and pathologic data were collected, and genetic testing for UMOD, MUC1, REN, and HNF1B was performed...
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29784614/tradeoffs-in-vascular-access-selection-in-elderly-patients-initiating-hemodialysis-with-a-catheter
#4
Timmy Lee, Joyce Qian, Mae Thamer, Michael Allon
RATIONALE & OBJECTIVE: National vascular access guidelines recommend placement of arteriovenous fistulas (AVFs) over grafts (AVGs) in hemodialysis patients, but have not been comprehensively assessed in the elderly. We evaluated clinically relevant vascular access outcomes in elderly patients receiving an AVF or AVG after hemodialysis therapy initiation. STUDY DESIGN: Retrospective cohort study using national administrative data. SETTINGS & PARTCIPANTS: Claims data from the US Renal Data System of 9,458 US patients 67 years and older who initiated hemodialysis therapy from July 1, 2010, to June 30, 2011, with a catheter and received an AVF (n=7,433) or AVG (n=2,025) within the ensuing 6 months...
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29784613/cryoglobulinemic-glomerulonephritis-associated-with-nodal-and-renal-infiltration-by-t-cell-lymphoma-of-t-follicular-helper-phenotype-a-case-report
#5
Jennifer Li, Marille Umakanathan, Chow Heok P'ng, Winny Varikatt, Fiona Kwok, Ming-Wei Lin, Mirna Vucak-Dzumhur
We present a unique case of cryoglobulinemic glomerulonephritis associated with nodal and renal infiltration by T-cell lymphoma of T-follicular helper phenotype. The patient presented with transient neurologic symptoms, severe nephritic syndrome with nephrotic-range proteinuria, and acute kidney injury. He had elevated double-stranded DNA levels, low complement levels, detectable cryoglobulin, and detectable immunoglobulin M (IgM) paraprotein. The kidney biopsy showed cryoglobulinemic glomerulonephritis with a membranoproliferative pattern and diffuse interstitial infiltrates on light microscopy; IgM, C3 but weak IgG, C1q, and negative C4d staining on immunofluorescence; and deposits with organized substructures on electron microscopy...
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29784612/risk-of-progression-of-nonalbuminuric-ckd-to-end-stage-kidney-disease-in-people-with-diabetes-the-cric-chronic-renal-insufficiency-cohort-study
#6
Digsu N Koye, Dianna J Magliano, Christopher M Reid, Christopher Jepson, Harold I Feldman, William H Herman, Jonathan E Shaw
BACKGROUND: Reduced glomerular filtration rate (GFR) in the absence of albuminuria is a common manifestation of chronic kidney disease (CKD) in diabetes. However, the frequency with which it progresses to end-stage kidney disease (ESKD) is unknown. STUDY DESIGN: Multicenter prospective cohort study. SETTING & PARTICIPANTS: We included 1,908 participants with diabetes and reduced GFR enrolled in the Chronic Renal Insufficiency Cohort (CRIC) Study in the United States...
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29784611/trends-in-left-ventricular-assist-device-implantation-and-associated-mortality-among-patients-with-and-without-esrd
#7
LETTER
Carl P Walther, Wolfgang C Winkelmayer, Anita Deswal, Jingbo Niu, Sankar D Navaneethan
No abstract text is available yet for this article.
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29784610/assessing-nephron-hyperplasia-in-fetal-congenital-solitary-functioning-kidneys-by-measuring-renal-papilla-number
#8
LETTER
Rozemarijn Snoek, Roel de Heus, Keetje J de Mooij, Lou R Pistorius, Marc R Lilien, A Titia Lely, Mireille N Bekker, Tom P V M de Jong
No abstract text is available yet for this article.
May 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29778273/erratum-regarding-bidirectional-association-of-retinal-vessel-diameters-and-estimated-gfr-decline-the-beaver-dam-ckd-study-am-j-kidney-dis-2011-57-5-682-691
#9
(no author information available yet)
No abstract text is available yet for this article.
May 16, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29751980/preserve-the-end-or-the-beginning-of-a-new-era-in-prevention-of-contrast-associated-acute-kidney-injury
#10
EDITORIAL
Richard Solomon
No abstract text is available yet for this article.
May 8, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29728318/non-vitamin-k-dependent-oral-anticoagulants-for-nonvalvular-atrial-fibrillation-in-patients-with-ckd-pragmatic-considerations-for-the-clinician
#11
Gautam R Shroff, Rachel Stoecker, Allyson Hart
Management of atrial fibrillation (AF) in patients with advanced chronic kidney disease (CKD) poses a complex conundrum because of higher risks for both thromboembolic and bleeding complications compared to the general population. This makes it particularly important for clinicians to carefully weigh the risks versus benefits of anticoagulation therapy to determine the individualized net clinical benefit for every patient. During the past few years, 4 non-vitamin K-dependent oral anticoagulant (NOAC) agents have supplemented warfarin in the therapeutic armamentarium for the prevention of systemic thromboembolism in nonvalvular AF...
May 2, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29728317/obesity-metabolic-abnormality-and-progression-of-ckd
#12
Hae-Ryong Yun, Hyoungnae Kim, Jung Tak Park, Tae Ik Chang, Tae-Hyun Yoo, Shin-Wook Kang, Kyu Hun Choi, Suah Sung, Soo Wan Kim, Joongyub Lee, Kook-Hwan Oh, Curie Ahn, Seung Hyeok Han
RATIONALE & OBJECTIVE: Recent studies have yielded conflicting findings on the association between obesity and progression of chronic kidney disease (CKD). Few studies have evaluated whether metabolic abnormalities may accelerate the rate of progression of CKD. STUDY DESIGN: Prospective observational cohort study. SETTING & PARTICIPANTS: 1,940 participants from the Korean Cohort Study for Outcome in Patients With Chronic Kidney Disease (KNOW-CKD) PREDICTORS: Obesity and metabolic abnormality...
May 2, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29728316/cognitive-impairment-in-non-dialysis-dependent-ckd-and-the-transition-to-dialysis-findings-from-the-chronic-renal-insufficiency-cohort-cric-study
#13
Meera N Harhay, Dawei Xie, Xiaoming Zhang, Chi-Yuan Hsu, Eric Vittinghoff, Alan S Go, Stephen M Sozio, Jacob Blumenthal, Stephen Seliger, Jing Chen, Rajat Deo, Mirela Dobre, Sanjeev Akkina, Peter P Reese, James P Lash, Kristine Yaffe, Manjula Kurella Tamura
BACKGROUND: Advanced chronic kidney disease is associated with elevated risk for cognitive impairment. However, it is not known whether and how cognitive impairment is associated with planning and preparation for end-stage renal disease. STUDY DESIGN: Retrospective observational study. SETTING & PARTICIPANTS: 630 adults participating in the CRIC (Chronic Renal Insufficiency Cohort) Study who had cognitive assessments in late-stage CKD, defined as estimated glome-rular filtration rate ≤ 20mL/min/1...
May 2, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29728315/ckd-genetic-variation-and-the-epigenome-decrypting-the-code
#14
EDITORIAL
John F O'Toole, John R Sedor
No abstract text is available yet for this article.
May 2, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29705074/kidney-transplantation-in-hiv-positive-patients-a-single-center-16-year-experience
#15
Gregory E Malat, Suzanne M Boyle, Rahul M Jindal, Stephen Guy, Gary Xiao, Meera N Harhay, Dong H Lee, Karthik M Ranganna, Mysore S Anil Kumar, Alden M Doyle
Hahnemann University Hospital has performed 120 kidney transplantations in human immunodeficiency virus (HIV)-positive individuals during the last 16 years. Our patient population represents ∼10% of the entire US population of HIV-positive kidney recipients. In our earlier years of HIV transplantation, we noted increased rejection rates, often leading to graft failure. We have established a multidisciplinary team and over the years have made substantial protocol modifications based on lessons learned. These modifications affected our approach to candidate evaluation, donor selection, perioperative immunosuppression, and posttransplantation monitoring and resulted in excellent posttransplantation outcomes, including 100% patient and graft survival at 1 year and patient and graft survival at 3 years of 100% and 96%, respectively...
April 25, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29699886/blood-lead-levels-and-decreased-kidney-function-in-a-population-based-cohort
#16
Florencia Harari, Gerd Sallsten, Anders Christensson, Marinka Petkovic, Bo Hedblad, Niklas Forsgard, Olle Melander, Peter M Nilsson, Yan Borné, Gunnar Engström, Lars Barregard
BACKGROUND: Environmental lead exposure has been associated with decreased kidney function, but evidence from large prospective cohort studies examining low exposure levels is scarce. We assessed the association of low levels of lead exposure with kidney function and kidney disease. STUDY DESIGN: Prospective population-based cohort. SETTING & PARTICIPANTS: 4,341 individuals aged 46 to 67 years enrolled into the Malmö Diet and Cancer Study-Cardiovascular Cohort (1991-1994) and 2,567 individuals subsequently followed up (2007-2012)...
April 23, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29699885/impact-of-a-primary-care-ckd-registry-in-a-us-public-safety-net-health-care-delivery-system-a-pragmatic-randomized-trial
#17
Delphine S Tuot, Charles E McCulloch, Alexandra Velasquez, Dean Schillinger, Chi-Yuan Hsu, Margaret Handley, Neil R Powe
BACKGROUND: Many individuals with chronic kidney disease (CKD) do not receive guideline-concordant care. We examined the impact of a team-based primary care CKD registry on clinical measures and processes of care among patients with CKD cared for in a public safety-net health care delivery system. STUDY DESIGN: Pragmatic trial of a CKD registry versus a usual-care registry for 1 year. SETTING & PARTICIPANTS: Primary care providers (PCPs) and their patients with CKD in a safety-net primary care setting in San Francisco...
April 23, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29699884/impact-of-telehealth-interventions-on-processes-and-quality-of-care-for-patients-with-esrd
#18
Meaghan Lunney, Raymond Lee, Karen Tang, Natasha Wiebe, Aminu K Bello, Chandra Thomas, Doreen Rabi, Marcello Tonelli, Matthew T James
Caring for patients with end-stage renal disease (ESRD) requiring dialysis is intensive and expensive. Telehealth may improve the access and efficiency of ESRD care. For this perspective, we systematically reviewed studies that examined the effectiveness of telehealth versus or in addition to usual care for ESRD management. 10 studies were identified, including 7 randomized trials and 3 cohort studies. Study populations, modes of delivery (including telephone, telemetry, or videoconferencing), and the outcomes evaluated varied substantially between studies...
April 23, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29680364/erratum-regarding-low-sodium-versus-standard-sodium-peritoneal-dialysis-solution-in-hypertensive-patients-a-randomized-controlled-trial-am-j-kidney-dis-2016-67-5-753-761
#19
(no author information available yet)
No abstract text is available yet for this article.
April 18, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29661542/helping-patients-with-esrd-and-earlier-stages-of-ckd-to-quit-smoking
#20
REVIEW
Perry Formanek, Elizabeth Salisbury-Afshar, Majid Afshar
Among the many adverse effects of tobacco exposure is the increased risk for progression of kidney disease. Individuals with chronic kidney disease (CKD), who already face increased cardiovascular event rates compared to the general population, are at even greater risk if they smoke. Despite these risks and the increased focus on smoking cessation in the general population in recent years, national guidelines have not specifically targeted individuals with CKD. There are similarly sparse data specific to individuals with CKD regarding the safety and efficacy of evidence-based smoking cessation modalities...
April 13, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
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