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American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation

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https://www.readbyqxmd.com/read/28549537/regional-differences-in-the-associations-between-prescribed-dialysate-sodium-concentration-and-interdialytic-weight-gain-in-the-dialysis-outcomes-and-practice-patterns-study
#1
LETTER
Manfred Hecking, Michelle M Y Wong, Friedrich K Port, Bruce M Robinson, Keith P McCullough
No abstract text is available yet for this article.
May 24, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28549536/non-gfr-determinants-of-low-molecular-weight-serum-protein-filtration-markers-in-the-elderly-ages-kidney-and-mesa-kidney
#2
Meredith C Foster, Andrew S Levey, Lesley A Inker, Tariq Shafi, Li Fan, Vilmundur Gudnason, Ronit Katz, Gary F Mitchell, Aghogho Okparavero, Runolfur Palsson, Wendy S Post, Michael G Shlipak
BACKGROUND: Studies in chronic kidney disease populations suggest that the non-glomerular filtration rate (GFR) determinants of serum levels of the low-molecular-weight protein filtration markers cystatin C, β2-microglobulin (B2M), and beta-trace protein (BTP) are less affected by age, sex, and ethnicity than those of creatinine. STUDY DESIGN: Cross-sectional study. SETTING & PARTICIPANTS: Predominantly elderly participants selected from the Age, Gene/Environment Susceptibility Kidney Study (AGES-Kidney; N=683; mean [SD] age, 79 [4] years; GFR, 62 [17]mL/min/1...
May 24, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28549535/relationships-of-measured-iohexol-gfr-and-estimated-gfr-with-ckd-related-biomarkers-in-children-and-adolescents
#3
Derek K Ng, George J Schwartz, Bradley A Warady, Susan L Furth, Alvaro Muñoz
BACKGROUND: 2 valid and reliable estimated glomerular filtration rate (GFR) equations for the pediatric population have been developed from directly measured GFR data in the Chronic Kidney Disease in Children (CKiD) cohort: the full CKiD and bedside CKiD equations. Although adult GFR estimating equations replicate relationships of measured GFR with biomarkers, it is unclear whether similar patterns exist among children and adolescents with chronic kidney disease (CKD). STUDY DESIGN: Prospective cohort study in children and adolescents...
May 24, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28549534/dabigatran-reversal-in-a-patient-with-end-stage-liver-disease%C3%A2-and-acute-kidney-injury
#4
James E Novak, Khalid Alamiri, Jerry Yee
Dabigatran, a direct thrombin inhibitor and one of the new class of direct oral anticoagulants, is increasingly used in preference to warfarin because of its efficacy and ease of administration. However, because the drug is cleared by the kidneys, it can accumulate in plasma and increase the risk for bleeding in patients with decreased kidney function. We report a patient with end-stage liver disease who developed life-threatening hemorrhage and acute kidney injury while taking dabigatran, 150mg, twice daily...
May 24, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28535904/evidence-and-renovascular-disease-trials-and-mistrials
#5
EDITORIAL
Stephen C Textor, Sandra M Herrmann
No abstract text is available yet for this article.
May 20, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28506789/assessing-the-effect-of-spironolactone-on-acute-kidney-injury-after-cardiac-surgery
#6
LETTER
Wei Zhang, Feng Xue, Hai Chen Chu
No abstract text is available yet for this article.
May 9, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28506788/in-reply-to-assessing-the-effect-of-spironolactone-on-acute-kidney-injury-after-cardiac-surgery
#7
LETTER
Magdalena Madero, Armando Vazquez-Rangel, Gerardo Gamba
No abstract text is available yet for this article.
May 9, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28495360/fractures-and-osteomalacia-in-a-patient-treated-with-frequent-home-hemodialysis
#8
Mark R Hanudel, Larry Froch, Barbara Gales, Harald Jüppner, Isidro B Salusky
Bone deformities and fractures are common consequences of renal osteodystrophy in the dialysis population. Persistent hypophosphatemia may be observed with more frequent home hemodialysis regimens, but the specific effects on the skeleton are unknown. We present a patient with end-stage renal disease treated with frequent home hemodialysis who developed severe bone pain and multiple fractures, including a hip fracture and a tibia-fibula fracture complicated by nonunion, rendering her nonambulatory and wheelchair bound for more than a year...
May 9, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28501241/in-reply-to-urinary-excretion-of-%C3%AE-1-microglobulin-does-not-predict-graft-loss-in-stable-kidney-transplant-recipients
#9
LETTER
Joachim H Ix, Vasantha Jotwani, Michael G Shlipak
No abstract text is available yet for this article.
May 5, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28501240/urinary-excretion-of-%C3%AE-1-microglobulin-does-not-predict-graft-loss-in-stable-kidney-transplant-recipients
#10
LETTER
Anneke P Bech, Judith M Hoogendijk, Jack F Wetzels
No abstract text is available yet for this article.
May 5, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28457656/stimulating-patient-engagement-in-medical-device-development%C3%A2-in-kidney-disease-a-report-of-a-kidney-health%C3%A2-initiative-workshop
#11
Frank P Hurst, Dolph Chianchiano, Linda Upchurch, Benjamin R Fisher, Jennifer E Flythe, Celeste Castillo Lee, Terri Hill, Carolyn Y Neuland
New technologies challenge current dialysis treatment paradigms as devices become smaller, more portable, and increasingly used outside the dialysis clinic. It is unclear how patients will view this care transition, and it will be important to consider patient and care partner perspectives during all aspects of development for novel dialysis therapies, from design and clinical trials to regulatory approval. To gain insight into this area, the Kidney Health Initiative, a public-private partnership between the American Society of Nephrology, the US Food and Drug Administration, and nearly 80 member organizations and companies dedicated to enhancing patient safety and fostering innovation in kidney disease, convened a workshop of patients, care partners, and other kidney community stakeholders...
April 27, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28456346/management-of-gout-and-hyperuricemia-in-ckd
#12
Ana Beatriz Vargas-Santos, Tuhina Neogi
Hyperuricemia and gout, the clinical manifestation of monosodium urate crystal deposition, are common in patients with chronic kidney disease (CKD). Although the presence of CKD poses additional challenges in gout management, effective urate lowering is possible for most patients with CKD. Initial doses of urate-lowering therapy are lower than in the non-CKD population, whereas incremental dose escalation is guided by regular monitoring of serum urate levels to reach the target level of <6mg/dL (or <5mg/dL for patients with tophi)...
April 26, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28456345/urinary-anomalies-in-22q11-2-deletion-digeorge-syndrome-from-copy-number-variations-to-single-gene-determinants%C3%A2-of%C3%A2-phenotype
#13
EDITORIAL
Gentzon Hall, Jonathan C Routh, Rasheed A Gbadegesin
No abstract text is available yet for this article.
April 26, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28450093/modified-creatinine-index-and-the-risk-of-bone-fracture-in-patients-undergoing-hemodialysis-the-q-cohort-study
#14
Shunsuke Yamada, Masatomo Taniguchi, Masanori Tokumoto, Ryota Yoshitomi, Hisako Yoshida, Narihito Tatsumoto, Hideki Hirakata, Satoru Fujimi, Takanari Kitazono, Kazuhiko Tsuruya
BACKGROUND: Hemodialysis patients are at increased risk for bone fracture and sarcopenia. There is close interplay between skeletal muscle and bone. However, it is still unclear whether lower skeletal muscle mass increases the risk for bone fracture. STUDY DESIGN: Cross-sectional study and prospective longitudinal cohort study. SETTING & PARTICIPANTS: An independent cohort of 78 hemodialysis patients in the cross-sectional study and 3,030 prevalent patients undergoing maintenance hemodialysis prospectively followed up for 4 years...
April 25, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28454686/opioid-overuse-or-nsaid-underuse-a%C3%A2-response-to-the-pain-guide
#15
LETTER
Swapnil Hiremath, David S Goldfarb, David N Juurlink
No abstract text is available yet for this article.
April 20, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28454685/in-reply-to-opioid-overuse-or-nsaid-underuse-a-response-to-the-pain-guide
#16
LETTER
Holly M Koncicki, Mark Unruh, Jane O Schell
No abstract text is available yet for this article.
April 20, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28438342/why-elain-and-akiki-should-not-be-compared-resolving-discordant-studies
#17
LETTER
Didier Dreyfuss, David Hajage, Stéphane Gaudry
No abstract text is available yet for this article.
April 18, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28438341/in-reply-to-why-elain-and-akiki-should-not-be-compared-resolving-discordant-studies
#18
LETTER
Ron Wald, Martin Gallagher, Sean M Bagshaw
No abstract text is available yet for this article.
April 18, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28416322/nephrologists-and-integrated-kidney-disease-care-roles-and-skills-essential-for-nephrologists-for-future-success
#19
Allen R Nissenson, Franklin W Maddux
As the costs of caring for patients with end-stage renal disease have grown, so has the pressure to provide high-quality care at a lower cost. Prompted in large part by regulatory and legislative changes, reimbursement is shifting from a fee-for-service environment to one of value-based payment models. Nephrologists in this new environment are increasingly responsible not only for direct patient care, but also for population management and the associated clinical outcomes for this vulnerable population. This Perspective article aims to recognize the key role and skills needed in order to successfully practice within these new value-based care models...
April 14, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28416321/targeted-deprescribing-in-an-outpatient-hemodialysis-unit-a%C3%A2-quality-improvement-study-to-decrease-polypharmacy
#20
Caitlin McIntyre, Rory McQuillan, Chaim Bell, Marisa Battistella
BACKGROUND: Polypharmacy in hemodialysis patients can result in adverse patient outcomes. Deprescribing tools can reduce polypharmacy, yet no method exists for an outpatient hemodialysis population. DESIGN: Quality improvement study. SETTING & PARTICIPANTS: 240 patients in a tertiary-care outpatient hemodialysis unit. QUALITY IMPROVEMENT PLAN: We aimed to: (1) develop a deprescribing tool for target medications with poor evidence for efficacy and safety, (2) determine its effectiveness in decreasing polypharmacy, and (3) monitor patient safety and satisfaction...
April 14, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
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