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American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation

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https://www.readbyqxmd.com/read/30219592/kidney-tattoos
#1
EDITORIAL
Jeffrey S Berns
No abstract text is available yet for this article.
September 12, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30201548/transplantation-of-a-gitelman-syndrome-kidney-ameliorates-hypertension-a-case-report
#2
Daniel Stewart, Daniela Iancu, Emma Ashton, Aisling E Courtney, Andrew Connor, Stephen B Walsh
Gitelman syndrome is caused by inactivating mutations of the gene that encodes the renal sodium/chloride cotransporter (NCC; encoded by SLC12A3), resulting in hypokalemia, hypomagnesemia, hypocalciuria, and metabolic alkalosis. Renal salt wasting commonly provokes mild hypotension. The paucity of previous kidney transplants from donors with known tubulopathies suggests that such conditions may be considered contraindications to donation. A 76-year-old man received a live unrelated kidney transplant from a donor with known Gitelman syndrome secondary to a pathogenic mutation of SLC12A3...
September 7, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30201547/use-of-renin-angiotensin-system-blockade-in-advanced-ckd-an-nkf-kdoqi-controversies-report
#3
Matthew R Weir, Jay I Lakkis, Bernard Jaar, Michael V Rocco, Michael J Choi, Holly Mattrix-Kramer, Elaine Ku
Multiple clinical trials have demonstrated that renin-angiotensin system (RAS) blockade with either angiotensin-converting enzyme inhibitors or angiotensin receptor blockers effectively reduces chronic kidney disease (CKD) progression. However, most clinical trials excluded participants with advanced CKD (ie, estimated glomerular filtration rate [eGFR]<30mL/min/1.73m2 ). It is acknowledged that initiation of RAS blockade is often associated with an acute reduction in eGFR, which is thought to be functional, but may result in long-term preservation of kidney function through the reductions in glomerular intracapillary pressure conferred by these agents...
September 7, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30201546/never-thought-i-would
#4
EDITORIAL
Ellen D Feld
No abstract text is available yet for this article.
September 7, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30201545/estimated-gfr-and-hospital-acquired-infections-following-major-surgery
#5
Junichi Ishigami, Marco Trevisan, Hong Xu, Josef Coresh, Kunihiro Matsushita, Juan-Jesus Carrero
RATIONALE & OBJECTIVE: Low estimated glomerular filtration rate (eGFR) increases infection risk, but its contribution to hospital-acquired infection following major surgery is unknown. STUDY DESIGN: Retrospective cohort study. SETTING & PARTICIPANTS: Residents of Stockholm, Sweden, 18 years or older with at least 1 recorded serum creatinine measurement, no recent diagnoses of infection, and hospitalized for orthopedic, abdominal, cardiothoracic and vascular, or neurologic surgery between January 2007 and December 2011...
September 7, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30177485/febuxostat-therapy-for-patients-with-stage-3-ckd-and-asymptomatic-hyperuricemia-a-randomized-trial
#6
Kenjiro Kimura, Tatsuo Hosoya, Shunya Uchida, Masaaki Inaba, Hirofumi Makino, Shoichi Maruyama, Sadayoshi Ito, Tetsuya Yamamoto, Yasuhiko Tomino, Iwao Ohno, Yugo Shibagaki, Satoshi Iimuro, Naohiko Imai, Masanari Kuwabara, Hiroshi Hayakawa, Hiroshi Ohtsu, Yasuo Ohashi
RATIONALE & OBJECTIVE: Epidemiologic and clinical studies have suggested that urate-lowering therapy may slow the progression of chronic kidney disease (CKD). However, definitive evidence is lacking. STUDY DESIGN: Randomized, double-blind, placebo-controlled trial. SETTING & PARTICIPANTS: 467 patients with stage 3 CKD and asymptomatic hyperuricemia at 55 medical institutions in Japan. INTERVENTION: Participants were randomly assigned in a 1:1 ratio to receive febuxostat or placebo for 108 weeks...
August 31, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30177484/incident-type-2-diabetes-among-individuals-with-ckd-findings-from-the-chronic-renal-insufficiency-cohort-cric-study
#7
Christopher Jepson, Jesse Y Hsu, Michael J Fischer, John W Kusek, James P Lash, Ana C Ricardo, Jeffrey R Schelling, Harold I Feldman
RATIONALE & OBJECTIVE: Few studies have examined incident type 2 diabetes mellitus (T2DM) in chronic kidney disease (CKD). Our objective was to examine rates of and risk factors for T2DM in CKD, using several alternative measures of glycemic control. STUDY DESIGN: Prospective cohort study. SETTING & PARTICIPANTS: 1,713 participants with reduced glomerular filtration rates and without diabetes at baseline, enrolled in the Chronic Renal Insufficiency Cohort (CRIC) Study...
August 31, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30166202/maintenance-of-certification-self-regulation-and-the-decline-of-physician-autonomy
#8
EDITORIAL
Tod Ibrahim
No abstract text is available yet for this article.
August 24, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30166201/transforming-the-american-board-of-internal-medicine-abim-and-maintenance-of-certification-moc
#9
EDITORIAL
Samir Nangia
No abstract text is available yet for this article.
August 24, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30149958/the-validity-of-drug-effects-on-proteinuria-albuminuria-serum-creatinine-and-estimated-gfr-as-surrogate-end-points-for-eskd-a-systematic-review
#10
Suetonia C Palmer, Marinella Ruospo, Armando Teixeira-Pinto, Jonathan C Craig, Petra Macaskill, Giovanni F M Strippoli
RATIONALE & OBJECTIVE: Proteinuria, albuminuria, and serum creatinine level are widely used as surrogate end point measures of end-stage kidney disease (ESKD). We evaluated the correlation between antihypertensive drug effects on surrogate renal end points and ESKD. STUDY DESIGN: Systematic review. SETTING & PARTICIPANTS: Randomized controlled trials of blood pressure-lowering therapy. SELECTION CRITERIA FOR STUDIES: Trials of pharmacological blood pressure-lowering strategies reporting drug effects on albuminuria, proteinuria, or serum creatinine level and ESKD through March 26, 2018...
August 24, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30149957/the-role-for-protein-restriction-in-addition-to-renin-angiotensin-aldosterone-system-inhibitors-in-the-management-of-ckd
#11
Laetitia Koppe, Denis Fouque
In experimental studies a low-protein diet (LPD) and renin-angiotensin-aldosterone system (RAAS) inhibitors are both reported to slow the progression of chronic kidney disease (CKD) and reduce proteinuria. RAAS activity contributes to increased blood pressure, fluid retention, and positive sodium balance, but also to kidney damage by enhancing glomerular capillary filtration pressure and synthesis of profibrotic molecules such as transforming growth factor β. It has been well established that an LPD decreases glomerular hyperfiltration and the generation of uremic toxins, as well as the burden of acid load, phosphorus, and sodium...
August 24, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30146423/risk-of-esrd-and-mortality-in-kidney-and-bladder-stone-formers
#12
Tsering Dhondup, Wonngarm Kittanamongkolchai, Lisa E Vaughan, Ramila A Mehta, Jasdeep K Chhina, Felicity T Enders, LaTonya J Hickson, John C Lieske, Andrew D Rule
RATIONALE & OBJECTIVES: Kidney stones have been associated with increased risk for end-stage renal disease (ESRD). However, it is unclear whether there is also an increased risk for mortality and if these risks are uniform across clinically distinct categories of stone formers. STUDY DESIGN: Historical matched-cohort study. SETTING & PARTICIPANTS: Stone formers in Olmsted County, MN, between 1984 and 2012 identified using International Classification of Diseases, Ninth Revision codes...
August 23, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30146422/innovations-in-wearable-and-implantable-artificial-kidneys
#13
Megha Salani, Shuvo Roy, William H Fissell
More than 2 million people worldwide receive treatment for end-stage renal disease (ESRD). Current modalities of renal replacement therapy include in-center hemodialysis, peritoneal dialysis, home hemodialysis, and kidney transplantation. Patient survival has gradually increased during the past 2 decades and efforts continue to improve mortality and quality of life for patients with ESRD. Developments in sorbent technology, nanotechnology, and cell culture techniques provide promise for new innovations in ESRD management...
August 23, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30146421/missed-hemodialysis-treatments-international-variation-predictors-and-outcomes-in-the-dialysis-outcomes-and-practice-patterns-study-dopps
#14
Issa Al Salmi, Maria Larkina, Mia Wang, Lalita Subramanian, Hal Morgenstern, Stefan H Jacobson, Raymond Hakim, Francesca Tentori, Rajiv Saran, Takashi Akiba, Natalia A Tomilina, Friedrich K Port, Bruce M Robinson, Ronald L Pisoni
RATIONALE & OBJECTIVE: Missed hemodialysis (HD) treatments not due to hospitalization have been associated with poor clinical outcomes and related in part to treatment nonadherence. Using data from the Dialysis Outcomes and Practice Patterns Study (DOPPS) phase 5 (2012-2015), we report findings from an international investigation of missed treatments among patients prescribed thrice-weekly HD. STUDY DESIGN: Prospective observational study. SETTING & PARTICIPANTS: 8,501 patients participating in DOPPS, on HD therapy for more than 120 days, from 20 countries...
August 23, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30146420/optimized-reference-intervals-for-plasma-free-metanephrines-in-patients-with-ckd
#15
LETTER
Christina Pamporaki, Aleksander Prejbisz, Robert Małecki, Frank Pistrosch, Mirko Peitzsch, Steffen Bishoff, Petra Mueller, Iris Meyer, Doreen Reimann, Katarzyna Hanus, Andrzej Januszewicz, Stefan R Bornstein, Simon Parmentier, Carola Kunath, Jacques W M Lenders, Graeme Eisenhofer, Jens Passauer
No abstract text is available yet for this article.
August 23, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30146419/emerging-concepts-in-hematopoietic-stem-cell-transplantation-associated-renal-thrombotic-microangiopathy-and-prospects-for-new-treatments
#16
REVIEW
Rimda Wanchoo, Ruthee L Bayer, Claude Bassil, Kenar D Jhaveri
Thrombotic microangiopathy associated with hematopoietic stem cell transplantation (HSCT-TMA) is a well-recognized complication of HSCT that has a high risk for death. Even in patients who survive, HSCT-TMA is associated with long-term morbidity and chronic organ injury. HSCT-TMA is a multisystem disease that often affects the kidneys. Renal manifestations of HSCT-TMA include reduced glomerular filtration rate, proteinuria, and hypertension. Understanding of the pathophysiology of HSCT-TMA has expanded in the last decade...
August 23, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30126676/erratum-regarding-risk-of-venous-thromboembolism-in-patients-by-albuminuria-and-estimated-gfr-am-j-kidney-dis-2017-70-6-826-833
#17
(no author information available yet)
No abstract text is available yet for this article.
August 17, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30122547/monitoring-urine-flow-to-prevent-overcorrection-of-hyponatremia-derivation-of-a-safe-upper-limit-based-on-the-edelman-equation
#18
LETTER
Florian Buchkremer, Stephan Segerer, Andreas Bock
No abstract text is available yet for this article.
August 16, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30122546/renal-disorders-in-pregnancy-core-curriculum-2019
#19
REVIEW
Maria L Gonzalez Suarez, Andrea Kattah, Joseph P Grande, Vesna Garovic
As the incidence of chronic kidney disease increases and women pursue pregnancy at more advanced ages, the management of kidney disease in pregnancy has become increasingly relevant to the practicing nephrologist. Women with kidney disorders face several challenges in pregnancy due to increased physiologic demands on the kidney and risk for disease progression, the potential teratogenicity of medications, and the increased risk for complications such as preeclampsia and preterm delivery. Challenges posed by an underlying disease process in pregnancy, such as autoimmune disease or diabetes mellitus, necessitate an interdisciplinary team to ensure good maternal and fetal outcomes...
August 16, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/30122545/outcomes-of-the-first-and-second-hemodialysis-fistula-a-cohort-study
#20
Fareed Kamar, Robert R Quinn, Matthew J Oliver, Andrea K Viecelli, Swapnil Hiremath, Jennifer MacRae, Lisa Miller, Peter Blake, Louise Moist, Amit X Garg, Ngan N Lam, Rameez Kabani, Alix Clarke, Ping Liu, Brenda Gillespie, Pietro Ravani
RATIONALE & OBJECTIVE: Fistulas are the preferred form of hemodialysis access; however, many fistulas fail to mature into usable accesses after creation. Data for outcomes after placement of a second fistula are limited. STUDY DESIGN: Cohort study. SETTING & PARTICIPANTS: People who initiated hemodialysis therapy in any of 5 Canadian dialysis programs (2004-2012) and had at least 1 hemodialysis fistula placed. PREDICTOR: Second versus initial fistula; receipt of 2 versus 1 fistula; second versus first fistula in recipients of 2 fistulas...
August 16, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
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