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Mayo Clinic Proceedings

Silvana B Sandbakk, Javaid Nauman, Nina Zisko, Øyvind Sandbakk, Nils Petter Aspvik, Dorthe Stensvold, Ulrik Wisløff
OBJECTIVE: To determine whether meeting physical activity (PA) recommendations and/or having high age-specific cardiorespiratory fitness (CRF) attenuate the adverse effect of prolonged sedentary time on cardiovascular risk factor (CV-RF) clustering in older adults. PATIENTS AND METHODS: We conducted a cross-sectional study of Norwegian women (495) and men (379) aged 70 to 77 years from August 22, 2012, through June 30, 2013. Sedentary time and PA were assessed by accelerometers and CRF by directly measured peak oxygen uptake (VO2peak)...
October 8, 2016: Mayo Clinic Proceedings
Tetsuro Tsujimoto, Hiroshi Kajio, Takehiro Sugiyama
OBJECTIVE: To assess whether obese diabetic patients with coronary heart disease (CHD) have a lower risk for cardiovascular or cardiac mortalities than do nonobese diabetic patients with CHD. PATIENTS AND METHODS: We conducted a prospective cohort study using data from the National Health and Nutrition Examination Survey 1999-2010 and followed up the study participants from the survey participation date until December 31, 2011. For primary analyses, we built Cox proportional hazard models restricted to diabetic patients with CHD; unadjusted and adjusted hazard rates of cardiovascular mortality were compared between obese and nonobese participants...
October 8, 2016: Mayo Clinic Proceedings
Laura E Walker, Annie T Sadosty, James E Colletti, Deepi G Goyal, Kharmene L Sunga, Sharonne N Hayes
Since 1995, women have comprised more than 40% of all medical school graduates. However, representation at leadership levels in medicine remains considerably lower. Gender representation among the American Board of Medical Specialties (ABMS) boards of directors (BODs) has not previously been evaluated. Our objective was to determine the relative representation of women on ABMS BODs and compare it with the in-training and in-practice gender composition of the respective specialties. The composition of the ABMS BODs was obtained from websites in March 2016 for all Member Boards...
October 7, 2016: Mayo Clinic Proceedings
Ruth E Bates, Mohamed Omer, Sahar S Abdelmoneim, Adelaide M Arruda-Olson, Christopher G Scott, Kent R Bailey, Robert B McCully, Patricia A Pellikka
OBJECTIVE: To evaluate the impact of screening stress testing for coronary artery disease in asymptomatic patients with diabetes in a community-based population. PATIENTS AND METHODS: This observational study included 3146 patients from Olmsted County, Minnesota, with no history of coronary artery disease or cardiac symptoms in whom diabetes was newly diagnosed from January 1, 1992, through December 31, 2008. With combined all-cause mortality and myocardial infarction as the primary outcome, weighted Cox proportional hazards regression was performed with screening stress testing within 2 years of diabetes diagnosis as the time-dependent covariate...
October 6, 2016: Mayo Clinic Proceedings
Freek R van de Schoor, Vincent L Aengevaeren, Maria T E Hopman, David L Oxborough, Keith P George, Paul D Thompson, Thijs M H Eijsvogels
Myocardial fibrosis (MF) is a common phenomenon in the late stages of diverse cardiac diseases and is a predictive factor for sudden cardiac death. Myocardial fibrosis detected by magnetic resonance imaging has also been reported in athletes. Regular exercise improves cardiovascular health, but there may be a limit of benefit in the exercise dose-response relationship. Intense exercise training could induce pathologic cardiac remodeling, ultimately leading to MF, but the clinical implications of MF in athletes are unknown...
October 6, 2016: Mayo Clinic Proceedings
Philipe de Souto Barreto, Julien Delrieu, Sandrine Andrieu, Bruno Vellas, Yves Rolland
OBJECTIVE: To examine the associations of physical activity (PA) frequency (both moderate and vigorous intensity) and PA levels with cognitive function. PATIENTS AND METHODS: Data of individuals 50 years or older, from 20 European countries (along with Israel), were collected from 2004 to November 2013 in the biannual Survey of Health, Ageing and Retirement in Europe. A total of 104,909 participants were assessed for cognitive function at least once (mean follow-up length, 29...
October 6, 2016: Mayo Clinic Proceedings
Matthew L Carlson, Nicholas L Deep, Neil S Patel, Larry B Lundy, Nicole M Tombers, Christine M Lohse, Michael J Link, Colin L Driscoll
OBJECTIVE: To elucidate the long-term clinical behavior, treatment, and outcomes of sporadic facial nerve schwannoma (FNS) in a large cohort of patients managed in the post-magnetic resonance imaging era. PATIENTS AND METHODS: Retrospective review at a single tertiary health care system (January 1, 1990, through December 31, 2015), evaluating 80 consecutive patients with sporadic FNS. RESULTS: Ninety-eight patients with FNS were identified; 10 with incomplete data and 8 with neurofibromatosis type 2 were excluded...
October 5, 2016: Mayo Clinic Proceedings
Liyong Zhang, David J Tester, Di Lang, Yili Chen, Jinxiang Zheng, Rui Gao, Robert F Corliss, Shuangbo Tang, John W Kyle, Chao Liu, Michael J Ackerman, Jonathan C Makielski, Jianding Cheng
OBJECTIVE: To look for previously unrecognized cardiac structural abnormalities and address the genetic cause for sudden unexplained nocturnal death syndrome (SUNDS). METHODS: Data for 148 SUNDS victims and 444 controls (matched 1:3 on sex, race, and age of death within 1 year) were collected from Sun Yat-sen University from January 1, 1998, to December 31, 2014, to search morphological changes. An additional 17 patients with Brugada syndrome (BrS) collected from January 1, 2006, to December 31, 2014, served as a comparative disease cohort...
October 1, 2016: Mayo Clinic Proceedings
Walter A Rocca, Liliana Gazzuola-Rocca, Carin Y Smith, Brandon R Grossardt, Stephanie S Faubion, Lynne T Shuster, James L Kirkland, Elizabeth A Stewart, Virginia M Miller
OBJECTIVE: To study the association between bilateral oophorectomy and the rate of accumulation of multimorbidity. PATIENTS AND METHODS: In this historical cohort study, the Rochester Epidemiology Project records-linkage system was used to identify all premenopausal women who underwent bilateral oophorectomy before age 50 years between January 1, 1988, and December 31, 2007, in Olmsted County, Minnesota. Each woman was randomly matched to a referent woman born in the same year (±1 year) who had not undergone bilateral oophorectomy...
September 28, 2016: Mayo Clinic Proceedings
Kimberly G Harmon, Irfan M Asif, Joseph J Maleszewski, David S Owens, Jordan M Prutkin, Jack C Salerno, Monica L Zigman, Rachel Ellenbogen, Ashwin L Rao, Michael J Ackerman, Jonathan A Drezner
OBJECTIVE: To determine the incidence and etiology of sudden cardiac arrest and death (SCA/D) in US high school athletes. PATIENTS AND METHODS: A prospective media database of SCA/D was queried for cases aged 14 to 18 years from 7 states over 6 school years (September 1, 2007, to August 30, 2013). Event details were investigated to determine participation on a high school athletic team, sex, sport, and occurrence during school-sponsored activity or exertion. National sports participation numbers were used and a conversion factor was applied to account for multisport athletes...
September 28, 2016: Mayo Clinic Proceedings
Jeannette M Olazagasti Lourido, Janice E Ma, Christine M Lohse, Jerry D Brewer
OBJECTIVE: To estimate the age- and sex-adjusted incidence of melanoma in adults 61 years or older in Olmsted County, Minnesota, from 1970 through 2009. PATIENTS AND METHODS: Using Rochester Epidemiology Project resources, 397 patients were identified who were 61 years or older and who received a first lifetime diagnosis of melanoma from January 1, 1970, through December 31, 2009, in Olmsted County. The incidence of melanoma and the overall and disease-specific survival rates were compared by age, sex, year of diagnosis, and stage of disease...
September 28, 2016: Mayo Clinic Proceedings
Matthew R Starr, Stanislav Henkin, Laura S Greenlund
No abstract text is available yet for this article.
August 9, 2016: Mayo Clinic Proceedings
Donnesha B Clayton, Kayin B Jeffers, M Caroline Burton
No abstract text is available yet for this article.
August 9, 2016: Mayo Clinic Proceedings
Michael H Bourne, Lynn A Fussner, Eva M Carmona
No abstract text is available yet for this article.
August 5, 2016: Mayo Clinic Proceedings
Moritz Binder, Hassan B Alkhateeb, Ronald S Go
No abstract text is available yet for this article.
August 4, 2016: Mayo Clinic Proceedings
Margaret R Wentz
Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as researched and interpreted by the author.
October 2016: Mayo Clinic Proceedings
Ryan C Romano, Melanie C Bois, Lori A Erickson
No abstract text is available yet for this article.
October 2016: Mayo Clinic Proceedings
Haleigh A James, Robert A Wermers
No abstract text is available yet for this article.
October 2016: Mayo Clinic Proceedings
Adil E Bharucha, Tae Hee Lee
Although pelvic pain is a symptom of several structural anorectal and pelvic disorders (eg, anal fissure, endometriosis, and pelvic inflammatory disease), this comprehensive review will focus on the 3 most common nonstructural, or functional, disorders associated with pelvic pain: functional anorectal pain (ie, levator ani syndrome, unspecified anorectal pain, and proctalgia fugax), interstitial cystitis/bladder pain syndrome, and chronic prostatitis/chronic pelvic pain syndrome. The first 2 conditions occur in both sexes, while the latter occurs only in men...
October 2016: Mayo Clinic Proceedings
Stuart J McCarter, Michael J Howell
Sleep disorders and neurodegenerative diseases are commonly encountered in primary care. A common, but underdiagnosed sleep disorder, rapid eye movement sleep behavior disorder (RBD), is highly associated with Parkinson disease and related disorders. Rapid eye movement sleep behavior disorder is common. It is estimated to affect 0.5% of the general population and more than 7% of individuals older than 60 years; however, most cases go unrecognized. Rapid eye movement sleep behavior disorder presents as dream enactment, often with patients thrashing, punching, and kicking while they are sleeping...
October 2016: Mayo Clinic Proceedings
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