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Mayo Clinic Proceedings

M Elizabeth Sublette
No abstract text is available yet for this article.
May 9, 2018: Mayo Clinic Proceedings
Paul A McAuley, Steven J Keteyian, Clinton A Brawner, Zeina A Dardari, Mahmoud Al Rifai, Jonathan K Ehrman, Mouaz H Al-Mallah, Seamus P Whelton, Michael J Blaha
OBJECTIVES: To assess the influence of exercise capacity and body mass index (BMI) on 10-year mortality in patients with heart failure (HF) and to synthesize these results with those of previous studies. PATIENTS AND METHODS: This large biracial sample included 774 men and women (mean age, 60±13 years; 372 [48%] black) with a baseline diagnosis of HF from the Henry Ford Exercise Testing (FIT) Project. All patients completed a symptom-limited maximal treadmill stress test from January 1, 1991, through May 31, 2009...
May 3, 2018: Mayo Clinic Proceedings
Rafael Harpaz, Rebecca M Dahl
We used administrative data to study the impact of family history on the risk of herpes zoster (HZ). Our HZ cases and our HZ family history were both ascertained on the basis of medically attended diagnoses, without reliance on self-report or recall bias. Family history was associated with HZ risk among both siblings and parents. The strength of the association differed when the index child was latently infected with vaccine-strain vs wild-type varicella zoster virus.
May 3, 2018: Mayo Clinic Proceedings
Timothy R Long, Katherine W Arendt, Beth A Elliott, Steven H Rose
No abstract text is available yet for this article.
May 2, 2018: Mayo Clinic Proceedings
José Miguel Rivera-Caravaca, María Asunción Esteve-Pastor, Francisco Marín, Mariano Valdés, Vicente Vicente, Vanessa Roldán, Gregory Y H Lip
OBJECTIVE: To investigate the incidence and risk of adverse clinical outcomes in a "real- world" cohort of patients with atrial fibrillation (AF) anticoagulated with vitamin K antagonists (VKAs) from the Murcia AF Project in comparison with the warfarin arm of the randomized clinical trial (RCT) AMADEUS (Evaluating the Use of SR34006 Compared to Warfarin or Acenocoumarol in Patients With Atrial Fibrillation). PATIENTS AND METHODS: We included 1361 patients with AF from the Murcia AF Project (recruitment from May 1, 2007, to December 1, 2007) and 2293 from the AMADEUS trial (started in September 2003 and primary completed in March 2006), all taking VKA treatment...
May 2, 2018: Mayo Clinic Proceedings
Daniel V Dudenkov, Kristin C Mara, Tanya M Petterson, Julie A Maxson, Tom D Thacher
OBJECTIVE: To determine the relationship between 25-hydroxyvitamin D (25[OH]D) values and all-cause and cause-specific mortality. PATIENTS AND METHODS: We identified all serum 25(OH)D measurements in adults residing in Olmsted County, Minnesota, between January 1, 2005, and December 31, 2011, through the Rochester Epidemiology Project. All-cause mortality was the primary outcome. Patients were followed up until their last clinical visit as an Olmsted County resident, December 31, 2014, or death...
May 2, 2018: Mayo Clinic Proceedings
Augustine S Lee, Jay H Ryu
Aspiration is a syndrome with variable respiratory manifestations that span acute, life-threatening illnesses, such as acute respiratory distress syndrome, to chronic, sometimes insidious, respiratory disorders such as aspiration bronchiolitis. Diagnostic testing is limited by the insensitivity of histologic testing, and although gastric biomarkers for aspiration are increasingly available, none have been clinically validated. The leading mechanism for microaspiration is thought to be gastroesophageal reflux disease, largely driven by the increased prevalence of gastroesophageal reflux across a variety of respiratory disorders, including chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, and chronic cough...
May 2, 2018: Mayo Clinic Proceedings
Miguel Teixeira, Laura S Greenlund
No abstract text is available yet for this article.
April 20, 2018: Mayo Clinic Proceedings
Jack H Short, Ayan Sen
No abstract text is available yet for this article.
April 20, 2018: Mayo Clinic Proceedings
Tanner J Bommersbach, Megan M Chock, Jennifer L Geske, J Michael Bostwick
OBJECTIVE: To explore what percentage of suicide decedents (SDs) vs controls were assessed for suicidality at medical appointments in the year before death. PATIENTS AND METHODS: Using the Rochester Epidemiology Project, 66 SDs dying in Olmsted County, Minnesota, between January 1, 2000, and December 31, 2009, were identified and matched with 141 age- and sex-matched controls. Blinded chart review determined how often providers screened and subjects endorsed suicidal ideation (SI)...
April 17, 2018: Mayo Clinic Proceedings
Dan P Ly, Anupam B Jena
Limited data exist on differences in time spent on household activities and child care between male and female physicians, which may influence sex differences in hours worked professionally. We studied sex differences among married physicians in time spent on household activities (eg, cleaning and cooking) and child care (eg, bathing and homework) from 2003 through 2016 using the American Time Use Survey, a detailed time use survey administered by the US Census. Overall, we found that female physicians with children spent 100...
April 12, 2018: Mayo Clinic Proceedings
Elad Maor, Jaskanwal D Sara, Diana M Orbelo, Lilach O Lerman, Yoram Levanon, Amir Lerman
OBJECTIVE: Voice signal analysis is an emerging noninvasive diagnostic tool. The current study tested the hypothesis that patient voice signal characteristics are associated with the presence of coronary artery disease (CAD). METHODS: The study population included 138 patients who were enrolled between January 1, 2015, and February 28, 2017: 37 control subjects and 101 subjects who underwent planned coronary angiogram. All subjects had their voice signal recorded to their smartphone 3 times: reading a text, describing a positive emotional experience, and describing a negative emotional experience...
April 12, 2018: Mayo Clinic Proceedings
Xin He, Chen Liu, Yili Chen, Jiangui He, Yugang Dong
OBJECTIVE: To assess the association of overweight without central obesity with risks of mortality. PATIENTS AND METHODS: We included 14,299 participants in the Third National Health and Nutrition Examination Survey (from October 18, 1988, through October 15, 1994). According to their body mass index and waist circumference, participants were categorized into 7 anthropometric groups. Logistic regression models were used to assess the relation of cardiovascular risk factors (hypertension, diabetes, or hypercholesterolemia) and 10-year cardiovascular risk to anthropometric groups...
April 12, 2018: Mayo Clinic Proceedings
Robert A Kyle, Dirk R Larson, Ellen D McPhail, Terry M Therneau, Angela Dispenzieri, Shaji Kumar, Prashant Kapoor, James R Cerhan, S Vincent Rajkumar
OBJECTIVE: To determine the incidence of Waldenström macroglobulinemia (WM) in a strictly defined geographic area over a 50-year period. PATIENTS AND METHODS: All residents of Olmsted County with a diagnosis of WM, consisting of a monoclonal IgM protein of any size and/or 10% or more lymphoplasmacytic infiltration of the bone marrow along with anemia, constitutional symptoms, hyperviscosity, lymphadenopathy, or hepatosplenomegaly requiring therapy, were identified from January 1, 1961, to December 31, 2010...
April 12, 2018: Mayo Clinic Proceedings
Hilda Guerra, Sean J Pittock, Kevin G Moder, James P Fryer, Avi Gadoth, Eoin P Flanagan
Antiphospholipid (aPL) antibodies have historically been postulated to cause a poorly understood inflammatory myelitis. Neuromyelitis optica spectrum disorder (NMOSD) causes an inflammatory longitudinally extensive transverse myelitis (LETM). In 2004, aquaporin-4 immunoglobulin G (AQP4-IgG) was first reported as a highly specific (>99%) serum diagnostic biomarker of NMOSD, distinguishing it from other disorders (eg, multiple sclerosis). We sought to assess the frequency of AQP4-IgG (and thus NMOSD diagnosis) in LETM with aPL antibodies...
April 11, 2018: Mayo Clinic Proceedings
Thom Rooke
No abstract text is available yet for this article.
April 9, 2018: Mayo Clinic Proceedings
Michael J Joyner
No abstract text is available yet for this article.
April 7, 2018: Mayo Clinic Proceedings
Steven Y Lin, Tait D Shanafelt, Steven M Asch
No abstract text is available yet for this article.
April 6, 2018: Mayo Clinic Proceedings
Trude Carlsen, Øyvind Salvesen, Xuemei Sui, Carl J Lavie, Steven N Blair, Ulrik Wisløff, Linda Ernstsen
OBJECTIVE: To assess the independent and combined associations of long-term changes in depressive symptoms (DSs) and estimated cardiorespiratory fitness (eCRF) with all-cause mortality. PARTICIPANTS AND METHODS: This is a longitudinal cohort study of 15,217 middle-aged and older individuals attending both the second (from August 15, 1995, through June 18, 1997) and third (from October 3, 2006, through June 25, 2008) health surveys of the Nord-Trøndelag Health Study, Norway, and followed until December 31, 2014...
March 24, 2018: Mayo Clinic Proceedings
Alvise Berti, Eric L Matteson, Cynthia S Crowson, Ulrich Specks, Divi Cornec
OBJECTIVE: To assess the cardiovascular disease (CVD) and venous thromboembolism (VTE) risks among patients with newly diagnosed antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV). PATIENTS AND METHODS: A population-based incident AAV cohort of 58 patients diagnosed between 1996 and 2015 in Olmsted County, MN, was identified by medical record review. For each patient, 3 age- and sex-matched non-AAV comparators were randomly selected from the same population and assigned an index date corresponding to the AAV incidence date...
March 24, 2018: Mayo Clinic Proceedings
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