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Mayo Clinic Proceedings

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https://www.readbyqxmd.com/read/28082018/association-between-exercise-capacity-and-late-onset-of-dementia-alzheimer-disease-and-cognitive-impairment
#1
Jan Müller, Khin Chan, Jonathan N Myers
OBJECTIVE: To address the association between exercise capacity and the onset of dementia, Alzheimer disease, and cognitive impairment. PATIENTS AND METHODS: For 6104 consecutive veteran patients (mean ± SD age: 59.2±11.4 years) referred for treadmill exercise testing, the combined end point of dementia, Alzheimer disease, and cognitive impairment was abstracted from the Veterans Affairs computerized patient record system. RESULTS: After mean ± SD follow-up of 10...
January 9, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28065514/review-of-childhood-obesity-from-epidemiology-etiology-and-comorbidities-to-clinical-assessment-and-treatment
#2
REVIEW
Seema Kumar, Aaron S Kelly
Childhood obesity has emerged as an important public health problem in the United States and other countries in the world. Currently 1 in 3 children in the United States is afflicted with overweight or obesity. The increasing prevalence of childhood obesity is associated with emergence of comorbidities previously considered to be "adult" diseases including type 2 diabetes mellitus, hypertension, nonalcoholic fatty liver disease, obstructive sleep apnea, and dyslipidemia. The most common cause of obesity in children is a positive energy balance due to caloric intake in excess of caloric expenditure combined with a genetic predisposition for weight gain...
January 5, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27955905/61-year-old-man-with-hypercalcemia-and-generalized-lymphadenopathy
#3
Ashley M Egan, Jarrett J Failing, Hiroshi Sekiguchi
No abstract text is available yet for this article.
December 9, 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27938891/reference-standards-for-cardiorespiratory-fitness-measured-with-cardiopulmonary-exercise-testing-using-cycle-ergometry-data-from-the-fitness-registry-and-the-importance-of-exercise-national-database-friend-registry
#4
Leonard A Kaminsky, Mary T Imboden, Ross Arena, Jonathan Myers
The importance of cardiorespiratory fitness (CRF) is well established. This report provides newly developed standards for CRF reference values derived from cardiopulmonary exercise testing (CPX) using cycle ergometry in the United States. Ten laboratories in the United States experienced in CPX administration with established quality control procedures contributed to the "Fitness Registry and the Importance of Exercise: A National Database" (FRIEND) Registry from April 2014 through May 2016. Data from 4494 maximal (respiratory exchange ratio, ≥1...
December 7, 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28017411/less-hidden-celiac-disease-but-increased-gluten-avoidance-without-a-diagnosis-in-the-united-states-findings-from-the-national-health-and-nutrition-examination-surveys-from-2009-to%C3%A2-2014
#5
Rok Seon Choung, Aynur Unalp-Arida, Constance E Ruhl, Tricia L Brantner, James E Everhart, Joseph A Murray
OBJECTIVE: To investigate the trends in the prevalence of diagnosed celiac disease (CD), undiagnosed CD, and people without celiac disease avoiding gluten (PWAG) in the civilian noninstitutionalized US population from 2009 to 2014. PATIENTS AND METHODS: We studied the occurrence of CD and PWAG in the 2009 to 2014 National Health and Nutrition Examination Surveys. The serum of all participants aged 6 years or older from the National Health and Nutrition Examination Surveys from 2009 to 2014 was tested for CD serology at Mayo Clinic...
December 5, 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27866655/prediction-of-cardiovascular-mortality-by-estimated-cardiorespiratory-fitness-independent-of-traditional-risk-factors-the-hunt-study
#6
Javaid Nauman, Bjarne M Nes, Carl J Lavie, Andrew S Jackson, Xuemei Sui, Jeff S Coombes, Steven N Blair, Ulrik Wisløff
OBJECTIVE: To assess the predictive value of estimated cardiorespiratory fitness (eCRF) and evaluate the additional contribution of traditional risk factors in cardiovascular disease (CVD) mortality prediction. PARTICIPANTS AND METHODS: The study included healthy men (n=18,721) and women (n=19,759) aged 30 to 74 years. A nonexercise algorithm estimated cardiorespiratory fitness. Cox proportional hazards models evaluated the primary (CVD mortality) and secondary (all-cause, ischemic heart disease, and stroke mortality) end points...
November 16, 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27855953/increasing-cardiac-rehabilitation-participation-from-20-to-70-a-road-map-from-the-million-hearts-cardiac-rehabilitation-collaborative
#7
REVIEW
Philip A Ades, Steven J Keteyian, Janet S Wright, Larry F Hamm, Karen Lui, Kimberly Newlin, Donald S Shepard, Randal J Thomas
The primary aim of the Million Hearts initiative is to prevent 1 million cardiovascular events over 5 years. Concordant with the Million Hearts' focus on achieving more than 70% performance in the "ABCS" of aspirin for those at risk, blood pressure control, cholesterol management, and smoking cessation, we outline the cardiovascular events that would be prevented and a road map to achieve more than 70% participation in cardiac rehabilitation (CR)/secondary prevention programs by the year 2022. Cardiac rehabilitation is a class Ia recommendation of the American Heart Association and the American College of Cardiology after myocardial infarction or coronary revascularization, promotes the ABCS along with lifestyle counseling and exercise, and is associated with decreased total mortality, cardiac mortality, and rehospitalizations...
November 14, 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28029347/enhancing-the-clinical-reasoning-skills-of-postgraduate-students-in-internal-medicine-through-medical-nonfiction-and-nonmedical-fiction-extracurricular-books
#8
H S Kiran, Thomas V Chacko, K A Sudharshana Murthy, H Basavana Gowdappa
OBJECTIVE: To improve the clinical reasoning skills of postgraduate students in internal medicine through 2 kinds of extracurricular books: medical nonfiction and nonmedical fiction. METHODS: Clinical reasoning is difficult to define, understand, observe, teach, and measure. This is an educational innovation under an experimental framework based on a cognitive intervention grounded in constructivist and cognitivist theories. This study was conducted from June 1, 2014, through May 31, 2015...
October 28, 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27902443/association-between-cataract-and-risk-of-incident-atrial-fibrillation-a-nationwide-population-based-retrospective-cohort-study
#9
Wei-Syun Hu, Cheng-Li Lin
OBJECTIVE: To identify the association between cataract and the subsequent atrial fibrillation (AF) risk. PATIENTS AND METHODS: Our retrospective cohort study was designed to analyze the Longitudinal Health Insurance Database 2000 of the Taiwan National Health Insurance program. We established a cataract cohort (n=39,347) and a noncataract cohort (n=39,347) to observe the incidence of AF. The cataract cohort included patients who were newly diagnosed with cataract from January 1, 2000, to December 31, 2010...
October 27, 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062069/the-medical-doctors-of-star-trek-leonard-bones-mccoy-and-beverly-crusher
#10
David P Steensma, Robert A Kyle
No abstract text is available yet for this article.
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062068/cervical-minimal-deviation-adenocarcinoma-in-peutz-jeghers-syndrome
#11
J Kenneth Schoolmeester, Lori A Erickson
No abstract text is available yet for this article.
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062067/applique-quilt-prince-s-feather-pattern-circa-1845
#12
Margaret R Wentz
Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author.
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062066/28-year-old-woman-with-malaise-cough-myalgia-and-dark-urine
#13
Mark Gurney, Thomas G Cotter, Christopher M Wittich
No abstract text is available yet for this article.
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062065/expanding-the-mayo-clinic-proceedings-mission-introducing-mayo-clinic-proceedings-innovations-quality-outcomes-mcp-iq-o
#14
EDITORIAL
William L Lanier, Thomas C Gerber
No abstract text is available yet for this article.
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062064/introduction-to-the-symposium-on-precision-medicine
#15
EDITORIAL
Timothy B Curry, Eric L Matteson, A Keith Stewart
No abstract text is available yet for this article.
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062063/an-uncommon-cause-of-new-onset-heart-failure
#16
Ami Schattner, Ina Dubin
No abstract text is available yet for this article.
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062062/whole-genome-sequencing-in-healthy-people
#17
REVIEW
Noralane M Lindor, Stephen N Thibodeau, Wylie Burke
Recent technological advances have radically changed genetic testing from an expensive and burdensome undertaking to a rapid and less costly option for many purposes. The utility of "next-generation" sequencing has been found to establish the diagnosis for hundreds of genetic disorders, to assess pharmacogenomic variants, and to identify treatable targets within malignant neoplasms. The ready availability of genomic information has led to the question of whether there would be clinical benefit of sequencing the genome of individuals who are not seeking a diagnosis, that is, genomic screening in generally healthy people, to provide anticipatory insights for their health care...
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062061/a-meta-analysis-of-randomized-controlled-trials-and-prospective-cohort-studies-of-eicosapentaenoic-and-docosahexaenoic-long-chain-omega-3-fatty-acids-and-coronary-heart-disease-risk
#18
Dominik D Alexander, Paige E Miller, Mary E Van Elswyk, Connye N Kuratko, Lauren C Bylsma
OBJECTIVE: To conduct meta-analyses of randomized controlled trials (RCTs) to estimate the effect of eicosapentaenoic and docosahexaenoic acid (EPA+DHA) on coronary heart disease (CHD), and to conduct meta-analyses of prospective cohort studies to estimate the association between EPA+DHA intake and CHD risk. METHODS: A systematic literature search of Ovid/Medline, PubMed, Embase, and the Cochrane Library from January 1, 1947, to November 2, 2015, was conducted; 18 RCTs and 16 prospective cohort studies examining EPA+DHA from foods or supplements and CHD, including myocardial infarction, sudden cardiac death, coronary death, and angina, were identified...
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062060/providing-appropriate-end-of-life-care-to-religious-and-ethnic-minorities
#19
REVIEW
Daniel K Partain, Cory Ingram, Jacob J Strand
There is overwhelming evidence that racial and ethnic minorities face multiple health care disparities. Recognizing and addressing cultural and religious/spiritual (RS) values is a critical aspect of providing goal-concordant care for patients facing a serious illness, especially at the end of life. Failure to address a patient's cultural and RS needs can lead to diminished quality of care and worse health outcomes. Given the multitude of cultural and RS values, we believe that a framework of cultural and RS curiosity along with a willingness to engage patients in discussions about these elements of their care within an interdisciplinary team should be the goal of all providers who are discussing goals, preferences, and values with patients facing advanced terminal illness...
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28062059/omega-3-fatty-acid-therapy-the-tide-turns-for-a-fish-story
#20
EDITORIAL
James H O'Keefe, Dany Jacob, Carl J Lavie
No abstract text is available yet for this article.
January 2017: Mayo Clinic Proceedings
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