We have located links that may give you full text access.
Racial Disparities in End-Stage Kidney Disease Outcomes Among Asians and Native Hawaiians and Other Pacific Islanders Across Geographic Residence.
American Journal of Nephrology 2023 September 20
INTRODUCTION: While Asians and Native Hawaiian and other Pacific Islanders (NHOPIs) have a high prevalence of kidney disease risk factors, there are sparse data examining their end-stage kidney disease (ESKD) outcomes. As Hawaii has high representation of Asians and NHOPIs, we compared their ESKD outcomes based on residence in the Mainland US vs. Hawaii/Pacific Islands (PIs).
MATERIALS AND METHODS: Using United States Renal Data System data, we examined the impact of geographic residence in the Mainland vs. Hawaii/PIs on race-mortality associations among incident ESKD patients transitioning to dialysis over 1/1/2000-12/31/2016 using Cox regression. We examined likelihood of post-dialysis kidney transplantation using Cox models and cumulative incidence curves.
RESULTS: Compared with White patients in the Mainland, Asians and NHOPIs in the Mainland had lower mortality: Adjusted HRs (aHRs) (95%CIs) 0.67 (0.66-0.67) and 0.72 (0.70-0.73), respectively. When examining Asians and NHOPIs in Hawaii/PIs, survival benefit was attenuated in Asians and diminished to the null in NHOPIs (ref: Mainland White patients). Cumulative incidence curves comparing Asian, NHOPI, and White patients showed Asians and NHOPIs in the Mainland had the highest likelihood of transplantation, whereas NHOPIs and Asians in Hawaii/PIs had the lowest likelihood.
DISCUSSION/CONCLUSION: In the Mainland, Asians and NHOPIs had lower mortality vs. White patients, whereas in Hawaii/PIs this survival benefit was diminished in Asians and mitigated in NHOPIs. NHOPIs and Asians in Hawaii/PIs had less transplantation vs. those in the Mainland. Further research is needed to uncover factors contributing to differential ESKD outcomes among Asians and NHOPIs across geographic residence.
MATERIALS AND METHODS: Using United States Renal Data System data, we examined the impact of geographic residence in the Mainland vs. Hawaii/PIs on race-mortality associations among incident ESKD patients transitioning to dialysis over 1/1/2000-12/31/2016 using Cox regression. We examined likelihood of post-dialysis kidney transplantation using Cox models and cumulative incidence curves.
RESULTS: Compared with White patients in the Mainland, Asians and NHOPIs in the Mainland had lower mortality: Adjusted HRs (aHRs) (95%CIs) 0.67 (0.66-0.67) and 0.72 (0.70-0.73), respectively. When examining Asians and NHOPIs in Hawaii/PIs, survival benefit was attenuated in Asians and diminished to the null in NHOPIs (ref: Mainland White patients). Cumulative incidence curves comparing Asian, NHOPI, and White patients showed Asians and NHOPIs in the Mainland had the highest likelihood of transplantation, whereas NHOPIs and Asians in Hawaii/PIs had the lowest likelihood.
DISCUSSION/CONCLUSION: In the Mainland, Asians and NHOPIs had lower mortality vs. White patients, whereas in Hawaii/PIs this survival benefit was diminished in Asians and mitigated in NHOPIs. NHOPIs and Asians in Hawaii/PIs had less transplantation vs. those in the Mainland. Further research is needed to uncover factors contributing to differential ESKD outcomes among Asians and NHOPIs across geographic residence.
Full text links
Related Resources
Trending Papers
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Prevention and treatment of ischaemic and haemorrhagic stroke in people with diabetes mellitus: a focus on glucose control and comorbidities.Diabetologia 2024 April 17
British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease.Rheumatology 2024 April 17
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Albumin: a comprehensive review and practical guideline for clinical use.European Journal of Clinical Pharmacology 2024 April 13
Eosinophilic Esophagitis: Clinical Pearls for Primary Care Providers and Gastroenterologists.Mayo Clinic Proceedings 2024 April
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app