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American Journal of Nephrology

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https://www.readbyqxmd.com/read/28633141/interaction-of-soluble-cxc-ligand-16-and-cardiac-injury-markers-in-hemodialysis-patients
#1
Wenjin Liu, Lulu Wang, Yongyue Wei, Xiurong Li, Chaoqing Gao, Jianmei Zhou, Liang Wang, Zhuxing Sun, Hong Chu, Youwei Bai, Junwei Yang
BACKGROUND: Recent data suggest that there is a pathogenic role for CXC ligand 16 (CXCL16) in cardiovascular diseases. Little is known about circulating CXCL16 in patients with kidney dysfunction. We explored the relationships of plasma CXCL16 with cardiac injury markers in a group of dialysis patients. METHODS: Plasma CXCL16 and C-reactive protein (CRP) were measured in 366 patients who were on maintenance hemodialysis. Cardiac injury was evaluated via measurements of the circulating B-type natriuretic peptide (BNP), N-terminal prohormone of brain natriuretic peptide (NT proBNP), Troponin I (TnI), and Troponin T (TnT)...
June 21, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28633134/peritoneal-water-transport-characteristics-of-diabetic-patients-undergoing-peritoneal-dialysis-a-longitudinal-study
#2
Ana Fernandes, Roi Ribera-Sanchez, Ana Rodríguez-Carmona, Antía López-Iglesias, Natacha Leite-Costa, Miguel Pérez Fontán
BACKGROUND: Volume overload is frequent in diabetics undergoing peritoneal dialysis (PD), and may play a significant role in the excess mortality observed in these patients. The characteristics of peritoneal water transport in this population have not been studied sufficiently. METHOD: Following a prospective, single-center design we made cross-sectional and longitudinal comparisons of peritoneal water transport in 2 relatively large samples of diabetic and nondiabetic PD patients...
June 21, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28618409/identification-of-8-novel-mutations-in-nephrogenesis-related-genes-in-chinese-han-patients-with-unilateral-renal-agenesis
#3
Hangdi Wu, Qian Xu, Jingyuan Xie, Jun Ma, Panpan Qiao, Wen Zhang, Haijin Yu, Weiming Wang, Ying Qian, Qianying Zhang, Yiqing Guo, Yonghua Tang, Xiao-Nong Chen, Zhaohui Wang, Nan Chen
BACKGROUND: Few genetic studies have focused on unilateral renal agenesis (URA), which is a disorder with insidious clinical manifestations and a tendency to result in renal failure. We aimed to detect pathogenic mutations in nephrogenesis-related genes, which were identified by a literature review conducted among a large cohort of Chinese Han patients with URA. METHODS: Totally, 86 unrelated URA patients were included. All URA patients were diagnosed by employing radiological methods...
June 16, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28614819/osteoprotegerin-is-the-strongest-predictor-for-progression-of-arterial-calcification-in-peritoneal-dialysis-patients
#4
Marcela Avila, Carmen Mora, María Del Carmen Prado, Miriam Zavala, Ramón Paniagua
BACKGROUND: Arterial calcification (AC) is frequent in patients with end stage renal disease and is also considered a risk factor for later morbidity and mortality. However, long-term factors associated with the process are not well known. We analyzed the trends over time of biomarkers related with development and progression of AC in incident patients on peritoneal dialysis (PD). METHODS: We performed a prospective study with 186 patients on PD followed up for 1 year...
June 15, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28614808/vascular-calcification-and-osteoprotegrin-in-chronic-kidney-disease
#5
M James Lenhard, Raelene E Maser
No abstract text is available yet for this article.
June 15, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28586769/validation-of-surrogates-of-urine-osmolality-in-population-studies
#6
Sonia Youhanna, Lise Bankir, Paul Jungers, David Porteous, Ozren Polasek, Murielle Bochud, Caroline Hayward, Olivier Devuyst
BACKGROUND: The importance of vasopressin and/or urine concentration in various kidney, cardiovascular, and metabolic diseases has been emphasized recently. Due to technical constraints, urine osmolality (Uosm), a direct reflect of urinary concentrating activity, is rarely measured in epidemiologic studies. METHODS: We analyzed 2 possible surrogates of Uosm in 4 large population-based cohorts (total n = 4,247) and in patients with chronic kidney disease (CKD, n = 146)...
June 7, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28564644/erythropoietin-hyporesponsiveness-in-dialysis-patients-possible-role-of-statins
#7
Takeshi Hasegawa, Junhui Zhao, Douglas S Fuller, Brian Bieber, Jarcy Zee, Hal Morgenstern, Norio Hanafusa, Masaomi Nangaku
BACKGROUND: Hypothesizing that statins may be useful as adjuvant treatment for renal anemia, we examined the association between statin prescription (Rx) and erythropoiesis-stimulating agent (ESA) hyporesponsiveness in Japanese hemodialysis (HD) patients prescribed ESAs. METHODS: We examined 3,602 patients in 60 HD facilities dialyzed 3 times/week for ≥4 months from the Japan Dialysis Outcomes and Practice Patterns Study phases 3-5 (2005-2015). Statin Rx was reported at the end of a 4-month interval (baseline) for each patient...
June 1, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28564640/impact-of-diabetes-on-extracellular-volume-status-in-patients-initiating-peritoneal-dialysis
#8
Aniema Udo, Catriona Goodlad, Andrew Davenport
BACKGROUND: Recent reports have highlighted that diabetic patients with kidney failure are at increased risk of technique failure and transfer to haemodialysis within 90 days of initiating peritoneal dialysis (PD). We wished to determine whether there were differences between diabetic and non-diabetic patients within the first 3 months of starting PD. METHODS: We reviewed results of corresponding bioimpedance and the 1st test of peritoneal membrane function (PET) in consecutive patients, 6-10 weeks after initiating PD electively...
June 1, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28554180/higher-ultrafiltration-rate-is-associated-with-longer-dialysis-recovery-time-in-patients-undergoing-conventional-hemodialysis
#9
Wael F Hussein, Rohini Arramreddy, Sumi J Sun, Marc Reiterman, Brigitte Schiller
BACKGROUND: Increased mortality and morbidity are reported in association with high ultrafiltration rate (UFR) and with long dialysis recovery time (DRT). We studied the association between UFR and DRT. METHODS: This is a cross-sectional, observational study was conducted. Patients on thrice-weekly hemodialysis (HD) with self-reported DRT between August and December 2014 were included. We examined the association of 30-day average UFR with recovery time. RESULTS: The total number of patients included in this study was 2,689...
May 30, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28554170/how-do-we-improve-the-quality-of-life-of-haemodialysis-patients-now-that-s-a-good-question
#10
Hugh C Rayner
No abstract text is available yet for this article.
May 30, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28554175/modification-of-potassium-mortality-relationship-by-ethnicity-and-race-solving-the-puzzle
#11
Rajiv Agarwal
No abstract text is available yet for this article.
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28538222/on-the-right-track-implementing-interventions-to-reduce-readmissions-in-dialysis-patients
#12
Laura C Plantinga, Bernard G Jaar
No abstract text is available yet for this article.
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28531901/a-comparison-between-intermittent-peritoneal-dialysis-and-automatic-peritoneal-dialysis-on-urgent-peritoneal-dialysis
#13
Chang Wang, Xiao Fu, Yuan Yang, Jun Deng, Hong-Qing Zhang, Hong-Mei Deng, Jia Lu, Youming Peng, Hong Liu, Fu-You Liu, Yinghong Liu
BACKGROUND: Urgent-start dialysis is a major problem for incident dialysis population. Urgent start on hemodialysis is associated with an increased risk of infectious or mechanical complications, and its mortality is equal to or higher than that of urgent start on peritoneal dialysis (PD). However, compared to patients starting PD in a planned setting, those on urgent-started PD have an increased risk of mechanical complications and lower technique survival. METHODS: In this study, 101 adult incident dialysis patients (≥18 years old) who underwent Tenckhoff catheter implantation were enrolled...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28531888/right-trac%C3%A2-post-hospitalization-care-transitions-program-to-reduce-readmissions-for-hemodialysis-patients
#14
Rebecca L Wingard, Kathryn McDougall, Billie Axley, Andrew Howard, Cathleen O''Keefe, Nancy Armistead, Janet R Lynch, Sophia Rosen, Len Usvyat, Franklin W Maddux
BACKGROUND: Hemodialysis (HD) patients have high hospitalization rates. This nonrandomized trial tested the effect of a bundle of renal-specific "Right TraC™" strategies on 30-day all-cause readmission rates and, secondarily, 90-day readmissions and overall admissions among HD patients. METHODS: Twenty-six Fresenius clinics in West Virginia, Ohio, and Kentucky participated in the interventions. Eighteen matched clinics served as controls; intervention clinics also served as their own controls...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28528337/association-between-chronic-kidney-disease-and-risk-of-cataract-a-nationwide-retrospective-cohort-study
#15
Yin-Tzu Liu, Tzu-Yao Hung, Yi-Kung Lee, Ming-Yuan Huang, Chen-Yang Hsu, Yung-Cheng Su
BACKGROUND: Previous studies have established a relationship between chronic kidney disease (CKD) and cataract, but the relationship between the severity of renal impairment and risk of cataract is uncertain. This study investigates the relationship between the severity of renal disease and cataract in a nationwide sample from Taiwan. METHODS: The cohort from 1-million National Health Insurance beneficiaries from Taiwan was retrospectively analyzed. All adult beneficiaries were followed from January 1, 2005 until December 31, 2013, to identify patients who underwent cataract surgeries...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28528336/racial-and-ethnic-differences-in-mortality-associated-with-serum-potassium-in-a-large-hemodialysis-cohort
#16
Taehee Kim, Connie M Rhee, Elani Streja, Melissa Soohoo, Yoshitsugu Obi, Jason A Chou, Amanda R Tortorici, Vanessa A Ravel, Csaba P Kovesdy, Kamyar Kalantar-Zadeh
BACKGROUND: Hyperkalemia is observed in chronic kidney disease patients and may be a risk factor for life-threatening arrhythmias and death. Race/ethnicity may be important modifiers of the potassium-mortality relationship in maintenance hemodialysis (MHD) patients given that potassium intake and excretion vary among minorities. METHODS: We examined racial/ethnic differences in baseline serum potassium levels and all-cause and cardiovascular mortality using Cox proportional hazard models and restricted cubic splines in a cohort of 102,241 incident MHD patients...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28528335/chronic-kidney-disease-and-cataract-seeing-the-light
#17
Heather G Mack, Judy Savige
No abstract text is available yet for this article.
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28514783/dialysis-access-as-an-area-of-improvement-in-elderly-incident-hemodialysis-patients-results-from-a-cohort-study-from-the-international-monitoring-dialysis-outcomes-initiative
#18
Jochen G Raimann, Claudia Barth, Len A Usvyat, Priscila Preciado, Bernard Canaud, Michael Etter, Xiaoqi Xu, Adrian Guinsburg, Christina Marelli, Neill Duncan, Albert Power, Frank M van der Sande, Jeroen P Kooman, Stephan Thijssen, Yuedong Wang, Peter Kotanko
BACKGROUND: Commencing hemodialysis (HD) using a catheter is associated with a higher risk of adverse outcomes, and early conversion from central-venous catheter (CVC) to arteriovenous fistula/graft (non-CVC) improves outcomes. We investigated CVC prevalence and conversion, and their effects on outcomes during the first year of HD in a multinational cohort of elderly patients. METHODS: Patients ≥70 years from the MONDO Initiative who commenced HD between 2000 and 2010 in Asia-Pacific, Europe, North-, and South-America and survived at least 6 months were included in this investigation...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28511179/vascular-access-in-the-elderly-does-one-size-fit-all
#19
Miten J Dhruve, Christopher T Chan
No abstract text is available yet for this article.
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28511172/donor-specific-anti-human-leukocyte-antigens-antibodies-acute-rejection-renal-function-and-histology-in-kidney-transplant-recipients-receiving-tacrolimus-and-everolimus
#20
Alexandra Ferreira, Claudia Felipe, Marina Cristelli, Laila Viana, Geovana Basso, Suelen Stopa, Juliana Mansur, Mayara Ivani, Adrieli Bessa, Priscila Ruppel, Wilson Aguiar, Erika Campos, Maria Gerbase-DeLima, Henrique Proença, Helio Tedesco-Silva, José Medina-Pestana
BACKGROUND: This analysis compared efficacy, renal function, and histology in kidney transplant recipients receiving tacrolimus (TAC) combined with everolimus (EVR) or mycophenolate (MPS). METHODS: This was a retrospective analysis from a randomized trial in kidney transplant recipients who received a single 3 mg/kg dose of rabbit antithymocyte globulin (r-ATG), TAC, EVR, and prednisone (PRED; r-ATG/EVR, n = 85), basiliximab (BAS), TAC, EVR, and PRED (BAS/EVR, n = 102) or BAS, TAC, MPS, and PRED (BAS/MPS, n = 101)...
2017: American Journal of Nephrology
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