We have located links that may give you full text access.
Receiver operating characteristic analysis under tree orderings of disease classes.
Statistics in Medicine 2016 May 21
Receiver operating characteristic (ROC) curve and its summary statistics (e.g., the area under curve (AUC)) are commonly used to evaluate the diagnostic accuracy for disease processes with binary classification. The ROC curve has been extended to ROC surface for scenarios with three ordinal classes or to hyper-surface for scenarios with more than three classes. For classifier under tree or umbrella ordering in which the marker measurement for one class is lower or higher than those for the other classes, the commonly adopted diagnostic measures are the naive AUC (NAUC) based on a pooled class of all the unordered classes and the umbrella volume (UV) based on the concept of volume under surface. However, both NAUC and UV have some limitations. For example, NAUC depends on the sampling weights for all the classes in population, and UV has only been introduced for three-class settings. In this article, we initiate the idea of a new ROC framework for tree or umbrella ordering (denoted as TROC) and propose the area under TROC curve (denoted as TAUC) as an appropriate diagnostic measure. The proposed TROC and TAUC share many nice features with the traditional ROC and AUC. Both parametric and nonparametric approaches are explored to construct the confidence interval estimation of TAUC. The performances of these methods are compared in simulation studies under a variety settings. At the end, the proposed methods are applied to a published microarray data set.
Full text links
Related Resources
Trending Papers
British Society of Gastroenterology guidelines for the management of hepatocellular carcinoma in adults.Gut 2024 April 17
Systemic lupus erythematosus.Lancet 2024 April 18
Should renin-angiotensin system inhibitors be held prior to major surgery?British Journal of Anaesthesia 2024 May
Ventilator Waveforms May Give Clues to Expiratory Muscle Activity.American Journal of Respiratory and Critical Care Medicine 2024 April 25
Acute Kidney Injury and Electrolyte Imbalances Caused by Dapagliflozin Short-Term Use.Pharmaceuticals 2024 March 27
Colorectal polypectomy and endoscopic mucosal resection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2024.Endoscopy 2024 April 27
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app