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British Journal of Anaesthesia

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https://www.readbyqxmd.com/read/29793617/corrigendum-to-perioperative-outcomes-in-the-context-of-mode-of-anaesthesia-for-patients-undergoing-hip-fracture-surgery-systematic-review-and-meta-analysis-br-j-anaesth-2018-120-37-50
#1
C M O'Donnell, L McLoughlin, C C Patterson, M Clarke, K C McCourt, M E McBrien, D F McAuley, M O Shields
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793616/alfaxalone-and-comments-on-thiopental-to-desflurane-an-anaesthetic-journey-where-are-we-going-next-br-j-anaesth-2017-119-i44-52
#2
LETTER
J Serrao, C Goodchild
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793615/safety-of-subsequent-general-anaesthesia-in-patients-allergic-to-neuromuscular-blocking-agents-value-of-allergy-skin-testing
#3
LETTER
A M Chiriac, C Tacquard, N B Fadhel, C Pellerin, J M Malinovsky, P M Mertes, P Demoly
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793614/occupational-exposure-to-methoxyflurane-administered-for-procedural-sedation-an-observational-study-of-40-exposures
#4
LETTER
R Ruff, S Kerr, D Kerr, D Zalcberg, J Stevens
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793613/over-delivery-of-desflurane-via-aisys-carestation-aladin2-cassette-%C3%A2-vaporiser
#5
LETTER
T W Foong, Y K G Tan
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793612/another-nail-in-the-saline-coffin
#6
LETTER
H-J Priebe
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793611/education-the-last-mile-to-universal-videolaryngoscopy
#7
LETTER
T-Y Wu
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793610/difficult-paediatric-airways-what-to-do
#8
LETTER
K Railton, I Adedugbe
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793609/attempting-tracheal-intubation-without-paralysis
#9
LETTER
J R Sneyd, E P O'Sullivan
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793608/fit-for-surgery-evidence-supporting-prehabilitation-programs
#10
LETTER
M Coca-Martinez, A Barberan-Garcia, R Risco, M Lopez-Baamonde, G Martinez-Palli
No abstract text is available yet for this article.
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793607/adverse-outcomes-after-planned-surgery-with-anticipated-intensive-care-admission-in-out-of-office-hours-time-periods-a-multicentre-cohort-study
#11
D J Morgan, K M Ho, M L Kolybaba, Y J Ong
BACKGROUND: Increasing mortality for patients admitted to hospitals during the weekend is a contentious but well described phenomenon. However, it remains uncertain whether adverse outcomes, including prolonged hospital length-of-stay (LOS), may also occur after patients undergoing major planned surgery are admitted to an intensive care unit (ICU) out-of-office-hours, either during weeknights (after 18:00) or on weekends. METHODS: All planned surgical admissions requiring admission to one of 183 ICUs across Australia and New Zealand between 2006 and 2016 were included in this retrospective population-based cohort study...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793606/the-anion-study-effect-of-different-crystalloid-solutions-on-acid-base-balance-physiology-and-survival-in-a-rodent-model-of-acute-isovolaemic-haemodilution
#12
N J Ekbal, P Hennis, A Dyson, M Mythen, M F M James, M Singer
BACKGROUND: Commercially available crystalloid solutions used for volume replacement do not exactly match the balance of electrolytes found in plasma. Large volume administration may lead to electrolyte imbalance and potential harm. We hypothesised that haemodilution using solutions containing different anions would result in diverse biochemical effects, particularly on acid-base status, and different outcomes. METHODS: Anaesthetised, fluid-resuscitated, male Wistar rats underwent isovolaemic haemodilution by removal of 10% blood volume every 15 min, followed by replacement with one of three crystalloid solutions based on acetate, lactate, or chloride...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793605/safety-and-clinical-effect-of-i-v-infusion-of-cyclopropyl-methoxycarbonyl-etomidate-abp-700-a-soft-analogue-of-etomidate-in-healthy-subjects
#13
B I Valk, A R Absalom, P Meyer, S Meier, I den Daas, K van Amsterdam, J A Campagna, S P Sweeney, M M R F Struys
BACKGROUND: Cyclopropyl-methoxycarbonyl metomidate, or ABP-700, is a second generation analogue of etomidate, developed to retain etomidate's beneficial haemodynamic and respiratory profile but diminishing its suppression of the adrenocortical axis. The objective of this study was to characterise the safety and efficacy of 30-min continuous infusions of ABP-700, and to assess its effect on haemodynamics and the adrenocortical response in healthy human volunteers. METHODS: Five cohorts involving 40 subjects received increasing infusion doses of ABP-700, propofol 60 μg kg-1  min-1 or placebo...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793604/influence-of-xenon-on-pulmonary-mechanics-and-lung-aeration-in-patients-with-healthy-lungs
#14
M S Schaefer, T A Treschan, J Gauch, M Neukirchen, P Kienbaum
BACKGROUND: The anaesthetic xenon shows potent organ-protective properties. Due to high density and dynamic viscosity, peak inspiratory pressure (Pmax ) increases during xenon application. Thus, barotrauma may counteract organ protection. Accordingly, we investigated the influence of xenon on lung mechanics and lung aeration in patients with normal and reduced thoracic wall compliance. METHODS: After registration and ethical approval, 20 patients free of pulmonary disease undergoing routine xenon-based anaesthesia were mechanically ventilated...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793603/effects-of-avoidance-or-use-of-neuromuscular-blocking-agents-on-outcomes-in-tracheal-intubation-a-cochrane-systematic-review
#15
REVIEW
L H Lundstrøm, C H V Duez, A K Nørskov, C V Rosenstock, J L Thomsen, A M Møller, S Strande, J Wetterslev
Cohort studies have indicated that avoidance of neuromuscular blocking agents (NMBA) is a risk factor for difficult tracheal intubation. However, the impact of avoiding NMBA on tracheal intubation, possible adverse effects, and postoperative discomfort has not been evaluated in a systematic review of randomised trials. We searched several databases for trials published until January 2017. We included randomised controlled trials comparing the effect of avoiding vs using NMBA. Two independent authors assessed risk of bias and extracted data...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793602/systematic-review-of-the-effects-of-fascia-iliaca-compartment-block-on-hip-fracture-patients-before-operation
#16
REVIEW
J Steenberg, A M Møller
BACKGROUND: Fascia iliaca compartment block is used for hip fractures in order to reduce pain, the need for systemic analgesia, and prevent delirium, on this basis. This systematic review was conducted to investigate the analgesic and adverse effects of fascia iliaca block on hip fracture in adults when applied before operation. METHODS: Nine databases were searched from inception until July 2016 yielding 11 randomised and quasi-randomised controlled trials, all using loss of resistance fascia iliaca compartment block, with a total population of 1062 patients...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793601/adiponectin-regulates-thermal-nociception-in-a-mouse-model-of-neuropathic-pain
#17
L Sun, H Li, L W Tai, P Gu, C W Cheung
BACKGROUND: Adiponectin, a cytokine secreted by adipocytes, plays an important role in regulating glucose and lipid metabolism. However, the role of adiponectin in pain conditions is largely unknown. This study aimed to identify the role and mechanism of adiponectin in nociceptive sensitivity under physiological and pathological states utilising adiponectin knockout (KO) mice. METHODS: Wild type (WT) and adiponectin KO mice were subjected to partial sciatic nerve ligation (pSNL) or sham operation...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793600/association-of-opioid-prescribing-practices-with-chronic-pain-and-benzodiazepine-co-prescription-a-primary-care-data-linkage-study
#18
N Torrance, R Mansoor, H Wang, S Gilbert, G J Macfarlane, M Serpell, A Baldacchino, T G Hales, P Donnan, G Wyper, B H Smith, L Colvin
BACKGROUND: Opioid prescribing is increasing worldwide with associated increases in misuse and other harms. We studied variations in national opioid prescription rates, indicators of prescribing quality, co-prescribing of benzodiazepines and relationship with pain severity in Scotland. METHODS: Electronic linkages of opioid prescribing in Scotland were determined from: (i) national data from Information Services Division, NHS Scotland (2003-2012); and (ii) individual data from Generation Scotland: Scottish Family Health Study...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793599/incidence-of-iatrogenic-opioid-dependence-or-abuse-in-patients-with-pain-who-were-exposed-to-opioid-analgesic-therapy-a-systematic-review-and-meta-analysis
#19
REVIEW
C Higgins, B H Smith, K Matthews
BACKGROUND: The prevalence and incidence of chronic conditions, such as pain and opioid dependence, have implications for policy development, resource allocation, and healthcare delivery. The primary objective of the current review was to estimate the incidence of iatrogenic opioid dependence or abuse after treatment with opioid analgesics. METHODS: Systematic electronic searches utilised six research databases (Embase, Medline, PubMed, Cinahl Plus, Web of Science, OpenGrey)...
June 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29793598/analgesic-mechanisms-of-gabapentinoids-and-effects-in-experimental-pain-models-a-narrative-review
#20
REVIEW
M Chincholkar
The focus of perioperative pain management should be to attempt to minimise the nociceptive input and reduce the risk of transition to central sensitisation. Gabapentinoids are being increasingly used as adjuncts for management of perioperative pain. Although gabapentinoids are classed as calcium channel blockers, their mechanisms of action are poorly understood. The analgesic effect in neuropathic pain is well evidenced but the role in postoperative pain is less certain. Medline and EMBASE database searches were conducted to identify studies relating to mechanisms of action and effects in experimental animal models of inflammatory and postoperative pain and human models of experimental pain...
June 2018: British Journal of Anaesthesia
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