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British Journal of Anaesthesia

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https://www.readbyqxmd.com/read/30442271/hip-fracture-outcomes-in-patients-with-chronic-obstructive-pulmonary-disease
#1
LETTER
L Buss, T M McKeever, J Nightingale, R Akyea, B Ollivere, I K Moppett, C E Bolton
No abstract text is available yet for this article.
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442270/prospective-randomised-trial-of-the-integrated-pulmonary-index%C3%A2-in-low-acuity-inpatients
#2
LETTER
R E Freundlich, J P Walco, D M Mueller, J P Wanderer, B S Rothman, M S Shotwell, W S Sandberg, P P Pandharipande, L M Weavind
No abstract text is available yet for this article.
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442269/monitoring-transpulmonary-pressure-during-anaesthesia-using-the-peep-step-method
#3
LETTER
O Stenqvist, P Persson, C A Stahl, S Lundin
No abstract text is available yet for this article.
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442268/syringe-labels-seen-through-the-eyes-of-the-colour-deficient-clinician
#4
LETTER
P B M Thomas, J D Mollon
No abstract text is available yet for this article.
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442267/characterising-the-effect-of-propofol-on-complexity-and-stability-in-the-eeg-power-spectrum
#5
LETTER
M Darracq, J Sleigh, M I Banks, R D Sanders
No abstract text is available yet for this article.
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442266/neuroprotective-properties-of-xenon-in-different-types-of-cns-injury
#6
LETTER
L Van Hese, L Al Tmimi, S Devroe, R D Sanders, S Fieuws, S Rex
No abstract text is available yet for this article.
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442265/use-of-cardiopulmonary-exercise-testing-in-the-perioperative-period-comment-on-br-j-anaesth-2018-121-496-7
#7
LETTER
K Kerr, A Mannings, A Kojro, K Wagstaff, J Whitaker
No abstract text is available yet for this article.
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442264/the-asos-surgical-risk-calculator-development-and-validation-of-a-tool-for-identifying-african-surgical-patients-at-risk-of-severe-postoperative-complications
#8
H-L Kluyts, Y le Manach, D M Munlemvo, F Madzimbamuto, A Basenero, Y Coulibaly, S Rakotoarison, V Gobin, A L Samateh, M S Chaibou, A O Omigbodun, S D Amanor-Boadu, J Tumukunde, T E Madiba, R M Pearse, B M Biccard
BACKGROUND: The African Surgical Outcomes Study (ASOS) showed that surgical patients in Africa have a mortality twice the global average. Existing risk assessment tools are not valid for use in this population because the pattern of risk for poor outcomes differs from high-income countries. The objective of this study was to derive and validate a simple, preoperative risk stratification tool to identify African surgical patients at risk for in-hospital postoperative mortality and severe complications...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442263/organisational-factors-and-mortality-after-an-emergency-laparotomy-multilevel-analysis-of-39-903-national-emergency-laparotomy-audit-patients
#9
C M Oliver, M G Bassett, T E Poulton, I D Anderson, D M Murray, M P Grocott, S R Moonesinghe
BACKGROUND: Studies across healthcare systems have demonstrated between-hospital variation in survival after an emergency laparotomy. We postulate that this variation can be explained by differences in perioperative process delivery, underpinning organisational structures, and associated hospital characteristics. METHODS: We performed this nationwide, registry-based, prospective cohort study using data from the National Emergency Laparotomy Audit organisational and patient audit data sets...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442262/facilitated-self-reported-anaesthetic-medication-errors-before-and-after-implementation-of-a-safety-bundle-and-barcode-based-safety-system
#10
T A Bowdle, S Jelacic, B Nair, K Togashi, K Caine, L Bussey, C Kruger, R Grieve, D Grieve, C S Webster, A F Merry
BACKGROUND: Anaesthetic medication administration errors are a significant threat to patient safety. In 2002, we began collecting data about the rate and nature of anaesthetic medication errors and implemented a variety of measures to reduce errors. METHODS: Facilitated self-reporting of errors was carried out in 2002-2003. Subsequently, a medication safety bundle including 'smart' infusion pumps were implemented. During 2014 facilitated self-reporting commenced again...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442261/seldinger-vs-modified-seldinger-techniques-for-ultrasound-guided-central-venous-catheterisation-in-neonates-a-randomised-controlled-trial
#11
I-K Song, E-H Kim, J-H Lee, Y-E Jang, H-S Kim, J-T Kim
BACKGROUND: Central venous catheterisation in neonates is difficult. The purpose of this study was to compare the Seldinger and modified Seldinger techniques for ultrasound-guided internal jugular vein catheterisation in neonates. METHODS: In this randomised, controlled trial, 120 neonates (≤1 month old) requiring central venous catheterisation under general anaesthesia were allocated into either the Seldinger (n=60) or the modified Seldinger (n=60) group. The primary outcome was the incidence of successful catheterisation on the first attempt...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442260/diagnostic-accuracy-of-a-calibrated-abdominal-compression-to-predict-fluid-responsiveness-in-children
#12
M Jacquet-Lagrèze, N Tiberghien, J-N Evain, N Hanna, S Courtil-Teyssedre, M Lilot, F Baudin, L Chardonnal, D Bompard, C Koffel, A Portefaix, E Javouhey, J-L Fellahi
BACKGROUND: Fluid administration to increase stroke volume index (SVi) is a cornerstone of haemodynamic resuscitation. We assessed the accuracy of SVi variation during a calibrated abdominal compression manoeuvre (ΔSVi-CAC) to predict fluid responsiveness in children. METHODS: Patients younger than 8 yr with acute circulatory failure, regardless of their ventilation status, were selected. SVi, calculated as the average of five velocity-time integrals multiplied by the left ventricular outflow tract surface area, was recorded at four different steps: baseline, after an abdominal compression with a calibrated pressure of 25 mm Hg, after return to baseline, and then after a volume expansion (VE) of 10 ml kg-1 lactated Ringer solution over 10 min...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442259/validation-of-the-pictorial-baxter-retching-faces-scale-for-the-measurement-of-the-severity-of-postoperative-nausea-in-spanish-speaking-children
#13
M F Watcha, E Medellin, A D Lee, M A Felberg, S A Bidani
BACKGROUND: As the intensity of nausea, a subjective symptom, is difficult to estimate in children, vomiting is used as the objective clinical endpoint in managing paediatric postoperative nausea and vomiting. The pictorial Baxter Retching Faces (BARF) scale is a validated quantitative measure of paediatric nausea, but versions in languages other than English have not been validated. METHODS: Healthy Spanish-speaking children aged 7-18 yr (n=184) undergoing elective ambulatory surgery rated perioperative pain and nausea using visual analogue (VAS) and pictorial Faces Pain Scale - Revised and BARF scales, along with a Likert scale measurement of symptom changes...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442258/effects-of-moderate-and-severe-arterial-hypotension-on-intracerebral-perfusion-and-brain-tissue-oxygenation-in-piglets
#14
S K Ringer, N G Clausen, N Spielmann, S Ohlerth, A Schwarz, M Weiss
BACKGROUND: Hypotension is common in anaesthetised children, and its impact on cerebral oxygenation is unknown. The goal of the present study was to investigate the effects of moderate systemic arterial hypotension (mHT) and severe hypotension (sHT) on cerebral perfusion and brain tissue oxygenation in piglets. METHODS: Twenty-seven anaesthetised piglets were randomly allocated to a control group, mHT group, or sHT group. Cerebral monitoring comprised a tissue oxygen partial pressure ( [Formula: see text] ) and laser Doppler (LD) perfusion probe advanced into the brain tissue, and a near-infrared spectroscopy sensor placed over the skin measuring regional oxygen saturation (rSO2 )...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442257/sevoflurane-based-anaesthesia-does-not-affect-already-impaired-cerebral-autoregulation-in-patients-with-type-2-diabetes-mellitus
#15
N H Sperna Weiland, J Hermanides, B J P van der Ster, M W Hollmann, B Preckel, W J Stok, J J van Lieshout, R V Immink
BACKGROUND: The baroreflex regulates arterial blood pressure (BP). During periods when blood pressure changes, cerebral blood flow (CBF) is kept constant by cerebral autoregulation (CA). In patients with diabetes mellitus (DM), low baroreflex sensitivity (BRS) is associated with impaired CA. As sevoflurane-based anaesthesia obliterates BRS, we hypothesised that this could aggravate the already impaired CA in patients with DM resulting in a 'double-hit' on cerebral perfusion leading to increased fluctuations in blood pressure and cerebral perfusion...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442256/mismatch-negativity-to-predict-subsequent-awakening-in-deeply-sedated-critically-ill-patients
#16
E Azabou, B Rohaut, R Porcher, N Heming, S Kandelman, J Allary, G Moneger, F Faugeras, J D Sitt, D Annane, F Lofaso, F Chrétien, J Mantz, L Naccache, T Sharshar
BACKGROUND: Mismatch negativity (MMN) is the neurophysiological correlate of cognitive integration of novel stimuli. Although MMN is a well-established predictor of awakening in non-sedated comatose patients, its prognostic value in deeply sedated critically ill patients remains unknown. The aim of this prospective, observational pilot study was to investigate the prognostic value of MMN for subsequent awakening in deeply sedated critically ill patients. METHODS: MMN was recorded in 43 deeply sedated critically ill patients on Day 3 of ICU admission using a classical 'odd-ball' paradigm that delivers rare deviant sounds in a train of frequent standard sounds...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442255/remifentanil-as-an-adjunct-to-anaesthesia-for-electroconvulsive-therapy-fails-to-confer-long-term-benefits
#17
U Kessler, J Bjorke-Bertheussen, E Søreide, P A Hunderi, L Bache-Mathiesen, K J Oedegaard, A Sartorius, H Schoeyen
BACKGROUND: Adding the μ-opioid receptor agonist remifentanil to agents used to induce general anaesthesia in electroconvulsive therapy (ECT) can reduce the required doses of induction agents and their unfavourable effects on seizure threshold and quality. However, whether remifentanil has favourable long-term treatment effects in terms of response and remission rates, speed of response and remission, and side-effects has not been studied. METHODS: This retrospective, register-based cohort study involved patients with major depression consecutively treated at two units at different hospitals in Norway with the same ECT procedure...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442254/neuroprotection-by-anaesthetics-in-rodent-models-of-traumatic-brain-injury-a-systematic-review-and-network-meta-analysis
#18
REVIEW
D P Archer, S K McCann, A M Walker, Z A Premji, K J Rogan, M J H Hutton, L J Gray
BACKGROUND: Anaesthetic neuroprotection in the setting of traumatic brain injury (TBI) remains unproved and is based upon the results in preclinical experiments. Here, we sought to synthesise the results in rodent models of TBI, and to evaluate the effects of publication bias, experimental manipulation, and poor study quality on the effect estimates. METHODS: After a systematic review, we used pairwise meta-analysis to estimate the effect of anaesthetics, opioids, and sedative-hypnotics on neurological outcome, and network meta-analysis to compare their relative efficacy...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442253/dexmedetomidine-attenuation-of-renal-ischaemia-reperfusion-injury-requires-sirtuin-3-activation
#19
Y Si, H Bao, L Han, L Chen, L Zeng, L Jing, Y Xing, Y Geng
BACKGROUND: Dexmedetomidine attenuates renal ischaemia and reperfusion (I/R) injury, but its mechanism of action is unclear. As sirtuin 3 (SIRT3) activation can alleviate acute kidney injury, we investigated whether dexmedetomidine acts through SIRT3 to reduce renal I/R injury. METHODS: The potential involvement of SIRT3 in dexmedetomidine attenuation of renal I/R injury was tested in HK2 cells subjected to hypoxia/reoxygenation and C57BL/6J mice subjected to renal I/R...
December 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30442252/micro-fragmented-fat-injection-reduces-sepsis-induced-acute-inflammatory-response-in-a-mouse-model
#20
A Bouglé, P Rocheteau, M Hivelin, A Haroche, D Briand, C Tremolada, J Mantz, F Chrétien
BACKGROUND: Severe sepsis has a high mortality rate. There is increasing evidence that human mesenchymal stem cells possess immunomodulatory properties in sepsis, particularly those from adipose tissue. We hypothesised that micro-fragmented human fat, obtained with minimal alteration of the stromal vascular niche, attenuates the inflammatory response and improves outcome in a murine model of sepsis. METHODS: Micro-fragmented fat, lipoaspirate, or saline was administered intraperitoneally 2 h after caecal ligation and puncture (CLP) in C57Bl/6RJ ketamine-xylazine anaesthetised mice...
December 2018: British Journal of Anaesthesia
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