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British Journal of Anaesthesia

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https://www.readbyqxmd.com/read/29452827/erratum-to-intraoperative-permissive-oliguria-how-much-is-too-much-br-j-anaesth-119-2017-1075-1077
#1
G Kunst, M Ostermann
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452826/hyperoxia-is-a-modifiable-anaesthetic-risk-factor-that-varies-in-the-practice-of-individual-anaesthetists
#2
LETTER
A K Staehr-Rye, T Kurth, F T Scheffenbichler, L S Rasmussen, M Eikermann
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452825/reverse-causation
#3
LETTER
Stijn W de Jonge, Linda M Posthuma, Quirine J J Boldingh, Marja A Boermeester, Markus W Hollmann
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452824/monitoring-rather-than-dose-matters-when-using-non-depolarising-neuromuscular-blocking-agents
#4
LETTER
A Y Oh
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452823/response-to-murphy-and-shelley
#5
LETTER
F de la Gala
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452822/evolution-of-observational-research-and-implementation-science-in-neuromuscular-pharmacology-to-improve-the-value-of-care
#6
LETTER
T Thevathasan, K J Ruscic, M Eikermann
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452821/do-larger-doses-of-neuromuscular-blocking-drugs-increase-postoperative-morbidity
#7
LETTER
J Norman
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452820/postoperative-pulmonary-complications-and-reversal-agents
#8
LETTER
J M Hunter
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452819/evidence-of-residual-neuromuscular-block-with-sugammadex-vs-neostigmine
#9
LETTER
A Abad-Gurumeta
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452818/medication-errors-in-paediatric-anaesthesia-a-cultural-change-is-urgently-needed
#10
LETTER
Jost Kaufmann, Mark Schieren, Frank Wappler
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452817/drug-errors-in-paediatric-anaesthesia-are-common-but-often-unreported-unless-actual-harm-occurs
#11
LETTER
Z A Burton, N Woodman, Z Harclerode, T Engelhardt
No abstract text is available yet for this article.
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452816/transnasal-humidified-rapid-insufflation-ventilatory-exchange-for-oxygenation-of-children-during-apnoea-a-prospective-randomised-controlled-trial
#12
T Riva, T H Pedersen, S Seiler, N Kasper, L Theiler, R Greif, M Kleine-Brueggeney
BACKGROUND: Transnasal humidified rapid insufflation ventilatory exchange (THRIVE) comprises the administration of heated, humidified, and blended air/oxygen mixtures via nasal cannula at rates of ≥2 litres kg -1 min -1 . The aim of this randomized controlled study was to evaluate the length of the safe apnoea time using THRIVE with two different oxygen concentrations (100% vs 30% oxygen) compared with standard low-flow 100% oxygen administration. METHODS: Sixty patients, aged 1-6 yr, weighing 10-20 kg, undergoing general anaesthesia for elective surgery, were randomly allocated to receive one of the following oxygen administration methods during apnoea: 1) low-flow 100% oxygen at 0...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452815/variable-versus-conventional-lung-protective-mechanical-ventilation-during-open-abdominal-surgery-provar-a-randomised-controlled-trial
#13
P M Spieth, A Güldner, C Uhlig, T Bluth, T Kiss, C Conrad, K Bischlager, A Braune, R Huhle, A Insorsi, F Tarantino, L Ball, M J Schultz, N Abolmaali, T Koch, P Pelosi, M Gama de Abreu
BACKGROUND: Experimental studies showed that controlled variable ventilation (CVV) yielded better pulmonary function compared to non-variable ventilation (CNV) in injured lungs. We hypothesized that CVV improves intraoperative and postoperative respiratory function in patients undergoing open abdominal surgery. METHODS: Fifty patients planned for open abdominal surgery lasting >3 h were randomly assigned to receive either CVV or CNV. Mean tidal volumes and PEEP were set at 8 ml kg -1 (predicted body weight) and 5 cm H 2 O, respectively...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452814/deep-or-awake-removal-of-laryngeal-mask-airway-in-children-at-risk-of-respiratory-adverse-events-undergoing-tonsillectomy-a-randomised-controlled-trial
#14
A Ramgolam, G L Hall, G Zhang, M Hegarty, B S von Ungern-Sternberg
BACKGROUND: Laryngeal mask airways (LMA) are widely used during tonsillectomies. Contrasting evidence exists regarding the timing of the removal and the risk of perioperative respiratory adverse events. We assessed whether the likelihood of perioperative respiratory adverse events is influenced by the timing of LMA removal in children with at least one risk factor for these events. METHODS: Participants (n=290, 0-16 yr) were randomised to have their LMA removed either deep (in theatre by anaesthetist at end-tidal sevoflurane >1 minimum alveolar concentration) or awake (in theatre by anaesthetist or in postanaesthesia care unit by anaesthetist or trained nurse)...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452813/incidence-characteristics-and-predictive-factors-for-medication-errors-in-paediatric-anaesthesia-a-prospective-incident-monitoring-study
#15
C Gariel, B Cogniat, F-P Desgranges, D Chassard, L Bouvet
BACKGROUND: Medication errors are not uncommon in hospitalized patients. Paediatric patients may have increased risk for medication errors related to complexity of weight-based dosing calculations or problems with drug preparation and dilution. This study aimed to determine the incidence of medication errors in paediatric anaesthesia in a university paediatric hospital, and to identify their characteristics and potential predictive factors. METHODS: This prospective incident monitoring study was conducted between November 2015 and January 2016 in an exclusively paediatric surgical centre...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452812/randomised-trial-comparing-forced-air-warming-to-the-upper-or-lower-body-to-prevent-hypothermia-during-thoracoscopic-surgery-in-the-lateral-decubitus-position
#16
S-H Min, S Yoon, S-H Yoon, J-H Bahk, J-H Seo
BACKGROUND: In the supine position, forced-air warming is more effective on the lower body than on the upper body to prevent intraoperative hypothermia. However, it is unknown in the lateral decubitus position. We thus compared forced-air warming on the upper and lower bodies in the lateral position. METHODS: Patients (n=123) were randomised to receive forced-air warming on the upper body or lower body during thoracoscopic surgery in the lateral position. We measured the nasopharyngeal temperature at 0, 30, 60, 90, and 120 min after lateral positioning during surgery and the infrared tympanic membrane temperature at 0, 30, 60, 90, and 120 min after surgery...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452811/effects-on-adult-cognitive-function-after-neonatal-exposure-to-clinically-relevant-doses-of-ionising-radiation-and-ketamine-in-mice
#17
S Buratovic, B Stenerlöw, S Sundell-Bergman, A Fredriksson, H Viberg, T Gordh, P Eriksson
BACKGROUND: Radiological methods for screening, diagnostics and therapy are frequently used in healthcare. In infants and children, anaesthesia/sedation is often used in these situations to relieve the patients' perception of stress or pain. Both ionising radiation (IR) and ketamine have been shown to induce developmental neurotoxic effects and this study aimed to identify the combined effects of these in a murine model. METHODS: Male mice were exposed to a single dose of ketamine (7...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452810/interleukin-6-is-both-necessary-and-sufficient-to-produce-perioperative-neurocognitive-disorder-in-mice
#18
J Hu, X Feng, M Valdearcos, D Lutrin, Y Uchida, S K Koliwad, M Maze
BACKGROUND: Perioperative neurocognitive disorders (PND) result in long-term morbidity and mortality with no effective interventions available. Because interleukin-6 (IL-6), a pro-inflammatory cytokine, is consistently up-regulated by trauma, including after surgery, we determined whether IL-6 is a putative therapeutic target for PND in a mouse model. METHODS: Following institutional approval, adult (12-14 weeks) male C57/Bl6 mice were pretreated with the IL-6 receptor (IL6R) blocking antibody tocilizumab prior to open tibia fracture with internal fixation under isoflurane anaesthesia...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452809/test-of-neural-inertia-in-humans-during-general-anaesthesia
#19
M H Kuizenga, P J Colin, K M E M Reyntjens, D J Touw, H Nalbat, F H Knotnerus, H E M Vereecke, M M R F Struys
BACKGROUND: Neural inertia is defined as the tendency of the central nervous system to resist transitions between arousal states. This phenomenon has been observed in mice and Drosophila anaesthetized with volatile anaesthetics: the effect-site concentration required to induce anaesthesia in 50% of the population (C50 ) was significantly higher than the effect-site concentration for 50% of the population to recover from anaesthesia. We evaluated this phenomenon in humans using propofol or sevoflurane (both with or without remifentanil) as anaesthetic agents...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452808/norepinephrine-exerts-an-inotropic-effect-during-the-early-phase-of-human-septic-shock
#20
O Hamzaoui, M Jozwiak, T Geffriaud, B Sztrymf, D Prat, F Jacobs, X Monnet, P Trouiller, C Richard, J L Teboul
BACKGROUND: We conducted this study to investigate whether norepinephrine increases cardiac contractility when administered during the early phase of septic shock. METHODS: We studied 38 patients with septic shock who had been resuscitated for <3 h and whose mean arterial pressure (MAP) remained <65 mm Hg. Echocardiographic variables were obtained before (T 0 ) and after either initiation or an increase in the dose of a norepinephrine infusion to increase MAP to ≥ 65 mm Hg (T 1 )...
March 2018: British Journal of Anaesthesia
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