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American Journal of Respiratory and Critical Care Medicine

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https://www.readbyqxmd.com/read/28231434/effects-of-retinoids-on-augmentation-of-club-cell-secretory-protein
#1
Yin Chen, Monica M Vasquez, Lingxiang Zhu, Rosa E Lizarraga, Mary Krutzsch, Janine Einspahr, David S Alberts, Peter Y P Di, Fernando D Martinez, Stefano Guerra
No abstract text is available yet for this article.
February 23, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28231028/high-flow-oxygen-peep-and-the-berlin-definition-of-ards-are-they-mutually-exclusive
#2
Jason Chertoff
No abstract text is available yet for this article.
February 23, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28231022/caution-regarding-catheter-directed-thrombolysis-cteph-mistaken-for-acute-submassive-pe
#3
Timothy M Fernandes, Victor G Pretorius, Nick H Kim
No abstract text is available yet for this article.
February 23, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28231020/could-niv-failure-rates-be-underestimated-in-the-lung-safe-study
#4
Rémi Coudroy, Jean-Pierre Frat, Arnaud W Thille
No abstract text is available yet for this article.
February 23, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28231018/reply-to-coudroy-et-al-and-chertoff
#5
Giacomo Bellani, Fabiana Madotto, Tài Pham, Eddy Fan, John G Laffey
No abstract text is available yet for this article.
February 23, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28222269/restoring-cftr-function-reduces-airway-bacteria-and-inflammation-in-people-with-cystic-fibrosis-and-chronic-lung-infections
#6
Katherine B Hisert, Sonya L Heltshe, Christopher Pope, Peter Jorth, Xia Wu, Rachael M Edwards, Matthew Radey, Frank J Accurso, Daniel J Wolter, Gordon Cooke, Ryan J Adam, Suzanne Carter, Brenda Grogan, Jan L Launspach, Seamas C Donnelly, Charles Gallagher, James E Bruce, David Stoltz, Michael J Welsh, Lucas R Hoffman, Edward F McKone, Pradeep K Singh
RATIONALE: Previous work indicates that ivacaftor improves CFTR activity and lung function in people with cystic fibrosis (CF) and G551D-CFTR mutations, but does not reduce density of bacteria or markers of inflammation in the airway. These findings raise the possibility that infection and inflammation may progress independently of CFTR activity once CF lung disease is established. OBJECTIVES: To better understand the relationship between CFTR activity, airway microbiology and inflammation, and lung function in subjects with CF and chronic airway infections...
February 21, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28222268/reply-to-complexity-analysis-of-respiratory-dynamics
#7
Cindy Thamrin, Urs Frey, David A Kaminsky, Helen K Reddel, Andrew J E Seely, Béla Suki, Peter J Sterk
No abstract text is available yet for this article.
February 21, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28222267/complexity-analysis-of-respiratory-dynamics
#8
Mohammad Reza Raoufy, Tara Ghafari, Ali R Mani
No abstract text is available yet for this article.
February 21, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28212057/pulse-pressure-variation-don-t-throw-the-baby-with-the-bathwater
#9
Sheila Nainan Myatra, Natesh R Prabu, Jigeeshu Vasishtha Divatia
No abstract text is available yet for this article.
February 17, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28212055/reply-to-lakhal-et-al-reply-to-myatra-et-al-and-reply-to-vistisen-et-al
#10
Philippe Vignon, Xavier Repessé, Julie Léger, Antoine Vieillard-Baron
No abstract text is available yet for this article.
February 17, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28212050/volume-controlled-ventilation-does-not-prevent-injurious-inflation-during-spontaneous-effort
#11
Takeshi Yoshida, Susumu Nakahashi, Maria Aparecida Miyuki Nakamura, Yukiko Koyama, Rollin Roldan, Vinicius Torsani, Roberta R De Santis, Susimeire Gomes, Akinori Uchiyama, Marcelo B P Amato, Brian P Kavanagh, Yuji Fujino
RATIONALE: Spontaneous breathing during mechanical ventilation increases transpulmonary pressure and tidal volume, and worsens lung injury. Intuitively, controlling tidal volume and transpulmonary pressure might limit injury from added spontaneous effort. OBJECTIVES: To test the hypothesis that during spontaneous effort in injured lungs, tidal volume and transpulmonary pressure limitation by volume-controlled ventilation results in less injurious patterns of inflation...
February 17, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28212049/dynamic-indices-derived-from-heart-lungs-interactions-incende-quod-adorasti
#12
Karim Lakhal, Stephan Ehrmann, Thierry Boulain
No abstract text is available yet for this article.
February 17, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28212048/can-passive-leg-raising-be-considered-gold-standard-in-predicting-fluid-responsiveness
#13
Simon T Vistisen, Johannes Enevoldsen, Thomas W L Scheeren
No abstract text is available yet for this article.
February 17, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28207282/treatment-of-post-transplant-complex-airway-stenosis-with-a-three-dimensional-computer-assisted-customized-airway-stent
#14
Nicolas Guibert, Alain Didier, Benjamin Moreno, Laurent Mhanna, Laurent Brouchet, Gavin Plat, Christophe Hermant, Julien Mazieres
No abstract text is available yet for this article.
February 16, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28207281/metastatic-cancer-mimicking-a-mycetoma
#15
Philip G Ong, Roberto F Casal, John Stewart, George A Eapen, Saadia A Faiz
No abstract text is available yet for this article.
February 16, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28207280/loss-of-atm-in-airway-epithelial-cells-is-associated-with-susceptibility-to-oxidative-stress
#16
Abrey J Yeo, Emmanuelle Fantino, Dorottya Czovek, Claire Wainwright, Peter D Sly, Martin F Lavin
No abstract text is available yet for this article.
February 16, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28207278/adult-langerhans-cell-histiocytosis-masquerading-as-hidradenitis-suppurativa
#17
Jason Chertoff, Julian Chung, Ali Ataya
N/A - Images.
February 16, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28199793/pulmonary-mucinous-cystadenocarcinoma-presenting-as-extensive-multifocal-cystic-lesions
#18
Vickie R Shannon, Amit S Nanda, Lavinia P Middleton, Saadia A Faiz
No abstract text is available yet for this article.
February 15, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28199173/accuracy-of-immunofluorescence-in-the-diagnosis-of-primary-ciliary-dyskinesia
#19
Amelia Shoemark, Emily Frost, Mellisa Dixon, Sarah Ollosson, Kate Kilpin, Mitali Patel, Juliet Scully, Andrew V Rogers, Hannah M Mitchison, Andrew Bush, Claire Hogg
Rationale The standard approach to diagnosis of primary ciliary dyskinesia (PCD) in the UK consists of assessing ciliary function by high-speed-microscopy and ultrastructure by election microscopy, but equipment and expertise is not widely available internationally. The identification of bi-allelic disease causing mutations is also diagnostic, but many disease causing genes are unknown, and testing is not widely available outside the USA. Fluorescent antibodies to ciliary proteins are used to validate research genetic studies, but diagnostic utility in this disease has not been systematically evaluated...
February 15, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28199135/extreme-trait-whole-genome-sequencing-identifies-ptpro-as-a-novel-candidate-gene-in-emphysema-with-severe-airflow-obstruction
#20
Josiah E Radder, Yingze Zhang, Alyssa D Gregory, Shibing Yu, Neil J Kelly, Joseph K Leader, Naftali Kaminski, Frank C Sciurba, Steven D Shapiro
RATIONALE: Genetic association studies in chronic obstructive pulmonary disease (COPD) have primarily tested for association with common variants, the results of which explain only a portion of disease heritability. As rare variation is also likely to contribute to susceptibility, we employed whole genome sequencing (WGS) of subjects with clinically extreme phenotypes to identify genomic regions enriched for rare variation contributing to COPD susceptibility. OBJECTIVE: Identify regions of rare genetic variation contributing to emphysema with severe airflow obstruction Methods: We identified heavy smokers that were resistant (n=65) or susceptible (n=64) to emphysema with severe airflow obstruction in the Pittsburgh SCCOR cohort...
February 15, 2017: American Journal of Respiratory and Critical Care Medicine
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