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Endoscopy

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https://www.readbyqxmd.com/read/28107766/long-term-clinical-outcomes-of-endoscopic-submucosal-dissection-for-colorectal-neoplasms-in-423-cases-a-retrospective-study
#1
Masayoshi Yamada, Yutaka Saito, Hiroyuki Takamaru, Hayato Sasaki, Takuya Yokota, Yasushi Matsuyama, Yoshinori Sato, Taku Sakamoto, Takeshi Nakajima, Hirokazu Taniguchi, Shigeki Sekine, Takahisa Matsuda
Background and study aim Endoscopic submucosal dissection (ESD) is known as a curative treatment for colorectal superficial neoplasms. There is however a need for more long-term clinical data to establish the full advantages of colorectal ESD regarding very low recurrence rates. The aim of this retrospective study was to determine long-term clinical outcomes of colorectal ESD. Methods A total of 423 lesions treated by ESD for colorectal adenoma/dysplasia or adenocarcinoma between 1998 and 2008 at a single high volume referral center were included...
January 20, 2017: Endoscopy
https://www.readbyqxmd.com/read/28107765/lower-adenoma-miss-rate-with-fuse-vs-conventional-colonoscopy-with-proximal-retroflexion-a-randomized-back-to-back-trial
#2
Ioannis S Papanikolaou, Periklis Apostolopoulos, Georgios Tziatzios, Erasmia Vlachou, Athanasios D Sioulas, Dimitrios Polymeros, Andreas Karameris, Ioannis Panayiotides, Georgios Alexandrakis, George D Dimitriadis, Konstantinos Triantafyllou
Background and study aims Full-spectrum colonoscopy (FSC) promises to increase adenoma detection by providing a wider field of view. The aim of this study was to compare adenoma miss rates of FSC with those of conventional colonoscopy complemented by right-colon re-examination using scope retroflexion (CC/R). Patients and methods At two tertiary endoscopy facilities, patients who were scheduled for colonoscopy for the assessment of symptoms or for colorectal cancer screening/surveillance were randomized (1:1) to undergo same-day, back-to-back colonoscopies (FSC or CC/R first), performed by one of five endoscopists who had documented adenoma detection rates > 35 %...
January 20, 2017: Endoscopy
https://www.readbyqxmd.com/read/28107764/endoscopic-ultrasound-guided-biliary-access-versus-precut-papillotomy-in-patients-with-failed-biliary-cannulation-a-retrospective-study
#3
Alexander Lee, Anupam Aditi, Yasser M Bhat, Kenneth F Binmoeller, Chris Hamerski, Oriol Sendino, Steve Kane, John P Cello, Lukejohn W Day, Medi Mohamadnejad, V Raman Muthusamy, Rabindra Watson, Jason B Klapman, Sri Komanduri, Sachin Wani, Janak N Shah
Background and aims Precut papillotomy is widely used after failed biliary cannulation. Endoscopic ultrasound (EUS)-guided biliary access techniques are newer methods to facilitate access and therapy in failed cannulation. We evaluated the impact of EUS-guided biliary access on endoscopic retrograde cholangiopancreatography (ERCP) success and compared these techniques to precut papillotomy. Patients and methods We retrospectively compared two ERCP cohorts. One cohort consisted of biliary ERCPs (n = 1053) attempted in patients with native papillae and surgically unaltered anatomy in whom precut papillotomy and/or EUS-guided biliary access were routinely performed immediately after failed cannulation...
January 20, 2017: Endoscopy
https://www.readbyqxmd.com/read/28107763/virtual-chromoendoscopy-i-scan-detects-more-polyps-in-patients-with-lynch-syndrome-a-randomized-controlled-crossover-trial
#4
Raf Bisschops, Sabine Tejpar, Hilde Willekens, Gert De Hertogh, Eric Van Cutsem
: Background and study aims (Virtual) chromoendoscopy detects more polyps than standard white-light endoscopy in patients with Lynch syndrome. Previous back-to-back trials did not randomize for the examination order, creating a possible bias in favor of chromoendoscopy. We aimed to assess the difference in polyp detection between high definition white-light endoscopy (HD-WLE) and virtual chromoendoscopy with I-SCAN in patients with Lynch syndrome. Patients and methods In this prospective, controlled trial, patients were randomized to either HD-WLE followed by I-SCAN (Group 1; n = 31) or I-SCAN followed by HD-WLE (Group 2; n = 30)...
January 20, 2017: Endoscopy
https://www.readbyqxmd.com/read/28107762/thulium-laser-in-interventional-endoscopy-animal-and-human-studies
#5
Gian E Tontini, Helmut Neumann, Luca Pastorelli, Luisa Spina, Flaminia Cavallaro, Paola Soriani, Alessandro Rimondi, Barbara Bruni, Claudio Clemente, Filippo Fagnani, Pavlos Lagoussis, Luca Carmignani, Maurizio Vecchi
Background and study aims The thulium laser system (TLS) is an emerging surgical tool. The 2-μm wavelength provides a confined coagulation depth (0.2 - 0.4 mm) to reduce the potential for inadvertent injuries. For the first time ever, we assessed TLS feasibility for endoscopic hemostasis ex vivo in pigs. In addition, we performed the first in vivo hemostatic treatments in humans. Patients and methods Tissue damage induced by TLS using different settings and optical fibers was compared to that from argon plasma coagulation (APC) in established ex vivo animal models...
January 20, 2017: Endoscopy
https://www.readbyqxmd.com/read/28107761/pre-emptive-endoscopic-vacuum-therapy-for-treatment-of-anastomotic-ischemia-after-esophageal-resections
#6
Philipp-Alexander Neumann, Rudolf Mennigen, Daniel Palmes, Norbert Senninger, Thorsten Vowinkel, Mike G Laukoetter
Background and study aims Endoscopic vacuum therapy (EVT) is a promising new approach for the treatment of anastomotic leakage in the gastrointestinal tract. Here, we present the first case series demonstrating successful use of EVT for the treatment of post-esophagectomy anastomotic ischemia prior to development of leakage. Patients and methods Between 2012 and 2015, intraluminal EVT was performed in eight patients with anastomotic ischemia following esophagectomy. The primary outcome measure was successful mucosal recovery...
January 20, 2017: Endoscopy
https://www.readbyqxmd.com/read/28103621/development-and-validation-of-a-training-module-on-the-use-of-acetic-acid-for-the-detection-of-barrett-s-neoplasia
#7
Fergus J Q Chedgy, Kesavan Kandiah, Hugh Barr, Simon Dwerryhouse, Balint Eross, Charles Gordon, Susi Green, Andy Li, James Brown, Gaius Longcroft-Wheaton, Pradeep Bhandari
Background and study aims Acetic acid chromoendoscopy (AAC) enhances the ability to correctly identify Barrett's neoplasia, and is increasingly used by both expert and nonexpert endoscopists. Despite its increasing use, there is no validated training strategy to achieve competence. The aims of our study were to develop a validated training tool in AAC-assisted lesion recognition, to assess endoscopists' baseline knowledge of AAC-assisted lesion recognition, and to evaluate the efficacy and impact of this training tool...
January 19, 2017: Endoscopy
https://www.readbyqxmd.com/read/28103620/a-novel-and-effective-delivery-method-for-polyglycolic-acid-sheets-to-post-endoscopic-submucosal-dissection-ulcers
#8
Toshitatsu Takao, Yoshitaka Takegawa, Hiroyuki Ono, Madoka Takao, Shiro Oka, Noriko Shinya, Hiromu Kutsumi, Takeshi Azuma
Background and aims Shielding methods for post-endoscopic submucosal dissection (ESD) ulcers have delivery-related problems. We developed an enveloped device for this purpose and evaluated its usefulness. Materials and methods Polyglycolic acid (PGA) sheets were delivered to six 3.0-cm ulcers in two resected porcine stomachs and six 5.0-cm ulcers in another three stomachs. In the regular method group, small PGA sheets were delivered via forceps. In the novel method group, a large PGA sheet was delivered via the new device...
January 19, 2017: Endoscopy
https://www.readbyqxmd.com/read/27997963/efficacy-of-the-cryoballoon-focal-ablation-system-for-the-eradication-of-dysplastic-barrett-s-esophagus-islands
#9
Hannah T Künzli, Dirk W Schölvinck, Sybren L Meijer, Kees A Seldenrijk, Jacques G H M Bergman, Bas L A M Weusten
Background and study aim Cryoablation can be used for the treatment of Barrett's esophagus (BE). A recent dosimetry study, using the CryoBalloon Focal Ablation System (CryoBalloon), demonstrated that 10-second ablations result in complete eradication of BE. However, the efficacy of 10-second ablation in a larger cohort of patients has not been investigated, nor has the potential of precise targeting of specific areas. The aim of the study was to assess the efficacy and performance (i. e. targeting of BE islands) of a 10-second cryoablation using the CryoBalloon...
December 20, 2016: Endoscopy
https://www.readbyqxmd.com/read/27975337/hospital-volume-and-adverse-events-following-esophageal-endoscopic-submucosal-dissection-in-japan
#10
Hiroyuki Odagiri, Hideo Yasunaga, Hiroki Matsui, Shigeru Matsui, Kiyohide Fushimi, Mitsuru Kaise
Background and study aims Esophageal endoscopic submucosal dissection (ESD) has gradually acquired popularity as a minimally invasive surgery for early cancers not only in Japan, but also in other countries. However, most reported outcomes have been based on relatively small samples of patients from specialized centers. Therefore, the association between hospital volume and the rate of adverse events following esophageal ESD has been poorly understood. Patients and methods Using a nationwide administrative database in Japan, we identified patients who underwent esophageal ESD between 1 July 2007 and 31 March 2013...
December 14, 2016: Endoscopy
https://www.readbyqxmd.com/read/27951611/clinical-implications-of-low-grade-dysplasia-found-during-inflammatory-bowel-disease-surveillance-a-retrospective-study-comparing-chromoendoscopy-and-white-light-endoscopy
#11
Joren R Ten Hove, Erik Mooiweer, Andrea E van der Meulen de Jong, Evelien Dekker, Cyriel Y Ponsioen, Peter D Siersema, Bas Oldenburg
Background and study aims: Current guidelines recommend the use of pancolonic chromoendoscopy for surveillance of patients with inflammatory bowel disease (IBD). It is currently unknown whether low grade dysplasia (LGD) found using chromoendoscopy carries a similar risk of high grade dysplasia (HGD) or colorectal cancer (CRC) compared with LGD detected using white-light endoscopy (WLE). The aim of this study was to compare the risk of advanced neoplasia, a combined endpoint of HGD and CRC, during follow-up after detection of lesions containing LGD identified with either chromoendoscopy or WLE...
December 12, 2016: Endoscopy
https://www.readbyqxmd.com/read/27951610/elipse-the-first-procedureless-gastric-balloon-for-weight-loss-a-prospective-observational-open-label-multicenter-study
#12
Evzen Machytka, Shantanu Gaur, Ram Chuttani, Martina Bojkova, Tomas Kupka, Marek Buzga, Andreas Giannakou, Kandiliotis Ioannis, Elisabeth Mathus-Vliegen, Samuel Levy, Ioannis Raftopoulos
Background and study aims: Conventional gastric balloons for weight loss require endoscopy for placement and removal. The Elipse device is swallowed, resides in the stomach for 4 months, and is then expelled. The objectives of this study were to assess the safety of Elipse and to measure its effects on weight loss, metabolic parameters, and quality of life. Methods: Each participant swallowed one Elipse device, which was filled with 550 mL of filling fluid through a thin delivery catheter that was then removed...
December 12, 2016: Endoscopy
https://www.readbyqxmd.com/read/27931050/improved-detection-of-right-colon-adenomas-with-additional-retroflexion-following-two-forward-view-examinations-a-prospective-study
#13
Hyun Seok Lee, Seong Woo Jeon, Hye Yoon Park, Seong Jae Yeo
Background and study aims Colonoscopy in the right colon is less effective than in the left colon in screening for colorectal cancer. The aim of this study was to prospectively evaluate the diagnostic value of retroflexion in the right colon. Patients and methods A total of 1020 patients undergoing screening or surveillance colonoscopy were enrolled. After the first cecal intubation, the scope was withdrawn from the cecum to the hepatic flexure in the standard forward view and all identified polyps were resected...
December 8, 2016: Endoscopy
https://www.readbyqxmd.com/read/27875855/endoscopic-ultrasound-guided-gallbladder-drainage-reduces-adverse-events-compared-with-percutaneous-cholecystostomy-in-patients-who-are-unfit-for-cholecystectomy
#14
Anthony Yuen Bun Teoh, Carlos Serna, Irene Penas, Charing Ching Ning Chong, Manuel Perez-Miranda, Enders K W Ng, James Yun Wong Lau
Background and study aim: There are no data comparing endoscopic ultrasound (EUS)-guided gallbladder drainage (EGBD) with percutaneous cholecystostomy as a treatment for patients with acute cholecystitis. Patients and methods: This was a 1 : 1 matched cohort study of all patients who were unfit for cholecystectomy and underwent EGBD or percutaneous cholecystostomy instead for the treatment of acute cholecystitis. The outcomes were matched for age, sex, and American Society of Anesthesiologists grade. Outcome measures included the technical and clinical success rates, adverse events, hospital stay, the number of unplanned admissions, and mortality...
November 22, 2016: Endoscopy
https://www.readbyqxmd.com/read/27855466/detection-of-lesions-in-dysplastic-barrett-s-esophagus-by-community-and-expert-endoscopists
#15
Dirk W Schölvinck, Kim van der Meulen, Jacques J G H M Bergman, Bas L A M Weusten
Background and aims: Endoscopic treatment of Barrett's esophagus (BE) consists of endoscopic resection of visible lesions followed by radiofrequency ablation (RFA) for any remaining flat BE. Because RFA is only justified in flat BE, detection of neoplastic lesions (high grade dysplasia [HGD] and early adenocarcinoma [EAC]) is crucial. We hypothesized that the detection of visible lesions containing HGD or EAC would be superior in BE expert centers compared with community hospitals, thereby supporting centralization of therapy for BE-related neoplasia...
November 17, 2016: Endoscopy
https://www.readbyqxmd.com/read/27852099/meta-analysis-of-the-performance-of-ultrathin-vs-standard-colonoscopes
#16
Aijaz Ahmed Sofi, Ali Nawras, Muhammad Ali Khan, Colin W Howden, Wade M Lee
Background and study aims: Colonoscopy should reliably intubate the cecum with minimal patient discomfort and without complications. Use of thinner endoscopes to overcome pain during the procedure has shown promise. However, the use of thinner scopes could lead to excess looping and difficulty with therapeutic procedures. The aim of this meta-analysis was to analyze the performance of ultrathin colonoscopes (UTC) and standard colonoscopes for routine colonoscopy. Patients and methods: We searched several electronic databases for all randomized controlled trials and nonrandomized (prospective) studies that compared the efficacies of UTC (diameter ≤ 9...
November 16, 2016: Endoscopy
https://www.readbyqxmd.com/read/27852098/premedication-with-simethicone-and-n-acetylcysteine-in-improving-visibility-during-upper-endoscopy-a-double-blind-randomized-trial
#17
Luís Elvas, Miguel Areia, Daniel Brito, Susana Alves, Sandra Saraiva, Ana T Cadime
Background and study aim: Upper endoscopy is the most common method for the diagnosis of upper gastrointestinal tract diseases. The aim of this study was to determine whether premedication with simethicone or N-acetylcysteine improves mucosal visualization during upper endoscopy. Patients and methods: This was a randomized, double-blind, placebo-controlled study of 297 patients scheduled for upper endoscopy who were premedicated 15 - 30 minutes before the procedure with: 100 mL of water (placebo, group A); water plus 100 mg simethicone (group B); water plus 100 mg simethicone plus 600 mg N-acetylcysteine (group C)...
November 16, 2016: Endoscopy
https://www.readbyqxmd.com/read/27842423/endoscopic-submucosal-dissection-for-early-rectal-neoplasia-experience-from-a-european-center
#18
Andreas Probst, Alanna Ebigbo, Bruno Märkl, Tina Schaller, Matthias Anthuber, Carola Fleischmann, Helmut Messmann
Background and study aims: Endoscopic resection is a curative treatment option for large nonpedunculated colorectal polyps (LNPCPs). Endoscopic submucosal dissection (ESD) allows en bloc resection but ESD experience is still limited outside Asia. The aim of our study was to evaluate the role of ESD in the treatment of early rectal neoplasia in a European center. Patients and methods: 330 patients referred for endoscopic resection of rectal LNPCPs were included prospectively. Results: ESD was performed for 302 LNPCPs (median diameter 40 mm)...
November 14, 2016: Endoscopy
https://www.readbyqxmd.com/read/27842422/the-adenoma-miss-rate-of-blue-laser-imaging-vs-white-light-imaging-during-colonoscopy-a-randomized-tandem-trial
#19
Ryo Shimoda, Yasuhisa Sakata, Takehiro Fujise, Kohei Yamanouchi, Nanae Tsuruoka, Megumi Hara, Atsushi Nakayama, Daisuke Yamaguchi, Takashi Akutagawa, Kazuma Fujimoto, Ryuichi Iwakiri
Background and study aims: The aim of the present study was to determine whether blue-laser imaging (BLI) reduced the miss rate of colon adenomatous lesions compared with conventional white-light imaging (WLI). Patients and methods: This was a prospective randomized study of patients undergoing screening and/or surveillance colonoscopy at Saga Medical School, Japan. A total of 127 patients were randomized to tandem colonoscopy with BLI followed by WLI (BLI-WLI group) or WLI followed by WLI (WLI-WLI group). The main outcome measure was the adenoma miss rate...
November 14, 2016: Endoscopy
https://www.readbyqxmd.com/read/27842421/a-newly-developed-continuous-zoom-focus-endocytoscope
#20
Youichi Kumagai, Kaiyo Takubo, Kenro Kawada, Morihiro Higashi, Toru Ishiguro, Jun Sobajima, Minoru Fukuchi, Kei-Ichiro Ishibashi, Erito Mochiki, Junko Aida, Tatsuyuki Kawano, Hideyuki Ishida
Background and study aims: We report the features of a newly developed endocytoscopy system (ECS), the GIF-Y0074. Patients and methods: The GIF-Y0074 offers high-definition resolution with a consecutive increase of magnification to × 500. Using ECS, we observed 32 cases of esophageal squamous cell carcinoma (ESCC), 11 cases of gastric cancer, and five cases of duodenal adenoma. Results: The images of cells obtained using the GIF-Y0074 at maximum magnification were brighter and clearer than those obtained with previous ECS systems...
November 14, 2016: Endoscopy
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