We have located links that may give you full text access.
Relationship between global and cortical cerebral blood flow in patients with head injuries
Neurosurgery 1999 June
OBJECTIVE: The goal of this study was to analyze the use of thermal diffusion-cerebral blood flow (TD-CBF) monitoring as a continuous monitoring method for patients with head injuries in the intensive care unit. METHODS: The TD-CBF probe was placed on normal-appearing frontal or parietal cortex at the time of surgery to treat traumatic intracranial hematomas in 35 patients, and cortical cerebral blood flow (CBF) was monitored for up to 7 days after surgery. We compared TD-CBF values with global CBF values measured by the standard Kety-Schmidt technique, and we compared changes in TD-CBF with changes in jugular venous oxygen saturation observed during intracranial pressure elevations. RESULTS: The average value for the global CBF measurements was 50.5+/-0.9 ml/100 g/min and that for the TD-CBF measurements was 60.5+/-1.4 ml/100 g/min; the average difference was 9.3+/-1.2 ml/100 g/min. The overall slope of the regression between the global CBF and TD-CBF measurements (n = 206) was 0.636 (comparison of observed slope with a slope of 0, P < 0.001). The relationship between the TD-CBF and global CBF values during 546 episodes of increased intracranial pressure was examined by comparing the changes in TD-CBF with the changes in jugular venous oxygen saturation. When the change in TD-CBF was at least 10 ml/100 g/min during an intracranial pressure elevation, the TD-CBF change reflected the change in jugular venous oxygen saturation on 85% of the occasions. CONCLUSION: The TD-CBF method is very convenient because of the continuous and automatic nature of the measurements. Most of the time, a change in TD-CBF indicated a similar change in global CBF. However, the limitations of local measurements of CBF must be kept in mind during therapeutic decision-making.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app