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Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

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https://www.readbyqxmd.com/read/28082270/modern-healthcare-versus-non-tuberculous-mycobacteria-who-will-have-the-upper-hand
#1
EDITORIAL
Matthew B Crist, Joseph F Perz
No abstract text is available yet for this article.
January 12, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28077522/increasing-numbers-of-new-kaposi-sarcoma-diagnoses-in-hiv-infected-children-and-adolescents-despite-the-wide-availability-of-antiretroviral-therapy-in-malawi
#2
LETTER
Nader Kim El-Mallawany, Jimmy Villiera, William Kamiyango, Joseph Mhango, Jeremy S Slone, Parth S Mehta, Peter N Kazembe, Michael E Scheurer
No abstract text is available yet for this article.
January 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28077521/reply-to-el-mllawanya-et-al
#3
LETTER
Julia Bohlius, Eliane Rohner, Matthias Egger
No abstract text is available yet for this article.
January 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28077520/hepatitis-e-virus-infection-in-anti-hev-igg-carryinfing-patients-after-successful-hcv-treatment-reactivation-or-reinfection
#4
Antonio Rivero-Juarez, Mario Frias, Pedro Lopez-Lopez, María de Los Angeles Risalde, Teresa Brieva, Isabel Machuca, Angela Camacho, Antonio Martinez-Peinado, Jose Carlos Gomez-Villamandos, Antonio Rivero
Although Hepatitis E (HEV) is regarded asa self-limiting infection and anti-HEV antibodies seem toprotect against reinfection, its pathogenesis is not well established. We describe two cases of acute symptomatic HEV infection after Hepatitis C therapy in patients carrying anti-HEV IgG antibodies raising two major questions: reactivation or reinfection?
January 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28077519/hiv-aids-in-iran
#5
Hossein Bannazadeh Baghi, Mohammad Aghazadeh, Jalil Rashedi, Behroz Mahdavi Poor
No abstract text is available yet for this article.
January 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28077518/th17-cytokine-responses-in-lyme-disease-correlate-with-borreliaburgdorferi-antibodies-during-early-infection-in-patients-with-erythema-migrans-and-with-autoantibodies-late-in-the-illness-in-patients-with-antibiotic-refractory-lyme-arthritis
#6
Klemen Strle, Katherine B Sulka, Annalisa Pianta, Jameson T Crowley, Sheila L Arvikar, Anthony Anselmo, Ruslan Sadreyev, Allen C Steere
BACKGROUND: Control of Lyme disease is attributed predominantly to innate and adaptive TH1 immune responses, whereas the role of TH17 responses is less clear. Here we characterized these inflammatory responses in patients with erythema migrans (EM) or Lyme arthritis (LA) to elucidate their role early and late in the infection. METHODS: Levels of 21 cytokines and chemokines, representative of innate, TH1, and TH17 immune responses, were assessed by Luminex in acute and convalescent sera from 91 EM patients, in serum and synovial fluid from 141 LA patients, and in serum from 57 healthy subjects...
January 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28077517/two-phase-hospital-associated-outbreak-of-mycobacterium-abscessus-investigation-and-mitigation
#7
Arthur W Baker, Sarah S Lewis, Barbara D Alexander, Luke F Chen, Richard J Wallace, Barbara A Brown-Elliott, Pamela J Isaacs, Lisa C Pickett, Chetan B Patel, Peter K Smith, John M Reynolds, Jill Engel, Cameron R Wolfe, Carmelo A Milano, Jacob N Schroder, Robert D Davis, Matthew G Hartwig, Jason E Stout, Nancy Strittholt, Eileen K Maziarz, Jennifer Horan Saullo, Kevin C Hazen, Richard J Walczak, Ravikiran Vasireddy, Sruthi Vasireddy, Celeste M McKnight, Deverick J Anderson, Daniel J Sexton
BACKGROUND: Nontuberculous mycobacteria (NTM) commonly colonize municipal water and cause healthcare-associated outbreaks. We investigated a biphasic outbreak of Mycobacterium abscessus at a tertiary care hospital. METHODS: Case patients had recent hospital exposure and laboratory-confirmed colonization or infection with M. abscessus from January 2013 through December 2015. We conducted a multidisciplinary epidemiologic, field, and laboratory investigation. RESULTS: The incidence rate of M...
January 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28077516/early-onset-invasive-candidiasis-in-extremely-low-birth-weight-infants-perinatal-acquisition-predicts-poor-outcome
#8
Michelle Barton, Alex Shen, Karel O'Brien, Joan L Robinson, H Dele Davies, Kim Simpson, Elizabeth Asztalos, Joanne Langley, Nicole Le Saux, Reginald Sauve, Anne Synnes, Ben Tan, Louis de Repentigny, Earl Rubin, Chuck Hui, Lajos Kovacs, Yvonne Cw Yau, Susan E Richardson
BACKGROUND: Neonatal invasive candidiasis (IC)presenting in the first week of life is less common and less well described than later onset IC. Risk factors, clinical features and disease outcomeshave not been studied in early onset disease (EOD, ≤7d) or compared to late onset disease (LOD, >7d). METHODS: All extremely low birth weight (ELBW, <1000g) cases with IC and controls froma multicentre study of neonatal candidiasisenrolledfrom 2001 to 2003were included in this study...
January 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28039340/intraseason-waning-of-influenza-vaccine-protection-evidence-from-the-us-influenza-vaccine-effectiveness-network-2011-12-through-2014-15
#9
Jill M Ferdinands, Alicia M Fry, Sue Reynolds, Joshua Petrie, Brendan Flannery, Michael L Jackson, Edward A Belongia
BACKGROUND: Recent studies suggest that influenza vaccine effectiveness (VE) may wane over the course of an influenza season, leading to suboptimal VE during late influenza seasons. METHODS: We examined the association between influenza VE and time since vaccination among patients ≥9 years old with medically-attended acute respiratory illness in the US Influenza Vaccine Effectiveness Network using data pooled from the 2011-12 through 2014-15 influenza seasons...
December 29, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28034888/ultra-short-course-antibiotics-for-patients-with-suspected-ventilator-associated-pneumonia-but-minimal-and-stable-ventilator-settings
#10
Michael Klompas, Lingling Li, John T Menchaca, Susan Gruber
PURPOSE: Many patients started on antibiotics for possible ventilator-associated pneumonia (VAP) do not have pneumonia. Patients with minimal and stable ventilator settings may be suitable candidates for early antibiotic discontinuation. We compared outcomes amongst patients with suspected VAP but minimal and stable ventilator settings treated with 1-3 versus >3 days of antibiotics. METHODS: We identified consecutive adult patients started on antibiotics for possible VAP with daily minimum PEEPs ≤5cm H2O and FiO2s ≤40% for at least 3 days within a large tertiary care hospital between 2006-2014...
December 29, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28034881/impact-of-intravenous-immunoglobulin-on-survival-in-necrotizing-fasciitis-with-vasopressor-dependent-shock-a-propensity-score-matched-analysis-from-130-us-hospitals
#11
Sameer S Kadri, Bruce J Swihart, Stephanie L Bonne, Samuel F Hohmann, Laura V Hennessy, Peter Louras, Heather L Evans, Chanu Rhee, Anthony F Suffredini, David C Hooper, Dean A Follmann, Eileen Bulger, Robert L Danner
BACKGROUND: Shock frequently complicates necrotizing fasciitis (NF) caused by group A streptococcus (GAS) or Staphylococcus aureus (SA). Intravenous immunoglobulin (IVIG) is sometimes administered for presumptive toxic shock syndrome (TSS), but its frequency of use and efficacy are unclear. METHODS: Adult patients with NF and vasopressor-dependent shock undergoing surgical debridement from 2010 to 2014 were identified at 130 U.S. hospitals. IVIG cases were propensity-matched and risk-adjusted...
December 29, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28034887/implementation-of-a-rapid-genotypic-assay-to-promote-targeted-ciprofloxacin-therapy-of-neisseria-gonorrhoeae-in-a-large-health-system
#12
Lao-Tzu Allan-Blitz, Romney M Humphries, Peera Hemarajata, Ashima Bhatti, Mark W Pandori, Mark J Siedner, Jeffrey D Klausner
Multidrug-resistant Neisseria gonorrhoeae is a top threat to public health. In November 2015, UCLA Health introduced a rapid gyrase A (gyrA) genotypic assay for prediction of Neisseria gonorrhoeae susceptibility to ciprofloxacin. We found a significant reduction in ceftriaxone use with a concomitant increase in targeted therapy.
December 28, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28034886/sustained-antibody-responses-six-years-following-one-two-or-three-doses-of-quadrivalent-hpv-vaccine-in-adolescent-fijian-girls-and-subsequent-responses-to-a-single-dose-of-bivalent-hpv-vaccine-a-prospective-cohort-study
#13
Zheng Quan Toh, Fiona M Russell, Rita Reyburn, James Fong, Evelyn Tuivaga, Tupou Ratu, Cattram D Nguyen, Rachel Devi, Mike Kama, Silivia Matanitobua, Sepehr N Tabrizi, Suzanne M Garland, Rohit Sinha, Ian Frazer, Lisi Tikoduadua, Joseph Kado, Eric Rafai, Edward K Mulholland, Paul V Licciardi
BACKGROUND: The antibody response following reduced HPV vaccine doses has not been determined. We compared the antibody responses in girls previously vaccinated with zero, one, two or three doses of 4vHPV (Gardasil(®),Merck Inc.) six years previously. METHODS: A prospective cohort study was undertaken in 200 Fijian girls (15-19 years old). Approximately equal numbers of girls from two main ethnic groups (Fijians-of-Indian-Descent;FIDs) and (Indigenous-Fijians;iTaukei) in Fiji were recruited for each dosage groups...
December 28, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28034885/occupational-hiv-infection-in-a-research-laboratory-with-unknown-mode-of-transmission-a-case-report
#14
Alessandro Soria, Claudia Alteri, Gabriella Scarlatti, Ada Bertoli, Monica Tolazzi, Emanuela Balestra, Maria Concetta Bellocchi, Fabio Continenza, Luca Carioti, Mara Biasin, Daria Trabattoni, Alessandra Bandera, Francesca Ceccherini-Silberstein, Carlo Federico Perno, Andrea Gori
A lab-worker was infected with HIV-1 in a biosafety level-2 of containment, without any apparent breach. Through full-genome sequencing and phylogenetic analyses, we could identify the source of infection in a replication-competent clone, unknowingly contaminating a safe experiment. Mode of transmission remains unclear. Caution is warranted when handling HIV-derived constructs.
December 28, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28034884/prognosticating-dengue
#15
EDITORIAL
Jenny Gh Low, Eng Eong Ooi
No abstract text is available yet for this article.
December 28, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28034883/an-evidence-based-algorithm-for-early-prognosis-of-severe-dengue-in-the-outpatient-setting
#16
Minh Tuan Nguyen, Thi Nhan Ho, Van Vinh Chau Nguyen, Thanh Hung Nguyen, Manh Tuan Ha, Van Tram Ta, Le Da Ha Nguyen, Loi Phan, Khoi Quang Han, Thi Hue Kien Duong, Nguyen Bich Chau Tran, Wills Bridget, Marcel Wolbers, Cameron P Simmons
BACKGROUND: Early prediction of severe dengue could significantly assist patient triage and case management METHODS: We prospectively investigated 7563 children with ≤3 days of fever recruited in the outpatient departments of six hospitals in southern Vietnam between 2010 and 2013. The primary endpoint of interest was severe dengue (2009 WHO Guidelines) and pre-defined risk variables were collected at the time of enrolment to enable prognostic model development. RESULTS: The analysis population comprised 7544 patients, of whom 2060 (27...
December 28, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28034882/a-risk-assessment-tool-for-identifying-pregnant-and-postpartum-women-who-may-benefit-from-pre-exposure-prophylaxis-prep
#17
LETTER
Jillian Pintye, Alison L Drake, John Kinuthia, Jennifer A Unger, Daniel Matemo, Renee Heffron, Ruanne Barnabas, Pamela Kohler, R Scott McClelland, Grace John-Stewart
BACKGROUND: An HIV risk assessment tool for pregnant women could identify women who would most benefit from PrEP while minimizing unnecessary PrEP exposure METHODS: Data from a prospective study of incident HIV among pregnant/postpartum women in Kenya was randomly divided into derivation (n=654) and validation (n=650) cohorts. A risk score was derived using multivariate Cox proportional hazards models and standard clinical prediction rules. Ability of the tool to predict maternal HIV acquisition was assessed using the area under the curve (AUC) and Brier score...
December 28, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28013258/epidemiology-of-carbapenem-resistant-klebsiella-pneumoniae-in-a-network-of-long-term-acute-care-hospitals
#18
Jennifer H Han, Ellie J C Goldstein, Jacqueleen Wise, Warren B Bilker, Pam Tolomeo, Ebbing Lautenbach
BACKGROUND: The rapid emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) represents a major public health threat, including in the long-term acute care hospital (LTACH) setting. The objective of this study was to describe the epidemiologic characteristics of CRKP in a network of United States LTACHs. METHODS: An observational study was performed among 64 LTACHs from January 2014 to March 2015. Clinical cultures were included, with the first CRKP isolate recovered from each patient per study quarter evaluated...
December 24, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28013257/use-of-proton-pump-inhibitors-and-the-risk-of-listeriosis-a-nationwide-registry-based-case-control-study
#19
Anne Kvistholm Jensen, Jacob Simonsen, Steen Ethelberg
BACKGROUND: Recent studies suggest that proton pump inhibitors (PPIs) may increase the risk for listeriosis. We aimed to investigate a potential association in cases of non-pregnancy associated listeriosis, using registry data. METHODS: We conducted a population-based case-control study using Danish health registries. Case-patients (n=721) were defined as patients ≥45 years notified with listeriosis, July 1994 to December 2012. We selected 34,800 control-subjects by risk-set sampling...
December 24, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28011615/impact-and-cost-effectiveness-of-selective-human-papillomavirus-vaccination-of-men-who-have-sex-with-men
#20
Allen Lin, Koh J Ong, Peter Hobbelen, Eleanor King, David Mesher, W John Edmunds, Pam Sonnenberg, Richard Gilson, Irenjeet Bains, Yoon H Choi, Clare Tanton, Kate Soldan, Mark Jit
BACKGROUND: Men who have sex with men (MSM) have a high lifetime risk of anogenital warts and cancers related to infection with human papillomavirus (HPV). They also benefit less from herd protection than heterosexual males in settings with female-only HPV vaccination. METHODS: We evaluated the potential health impact and cost-effectiveness of offering vaccination to MSM who visit genito-urinary medicine clinics. We used a mathematical model of HPV 6/11/16/18 sexual transmission within an MSM population in England, parameterised with sexual behaviour, GUM attendance, HPV prevalence, HIV prevalence, warts and cancer incidence data...
December 23, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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