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Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

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https://www.readbyqxmd.com/read/30520997/reply-to-ambrosioni-et-al
#1
Huldrych F Günthard, Vincent Calvez, Roger Paredes, Deenan Pillay, Robert W Shafer, Annemarie M Wensing, Donna M Jacobsen, Douglas D Richman
No abstract text is available yet for this article.
December 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30520993/resistance-testing-for-integrase-strand-transfer-inhibitors-in-na%C3%A3-ve-hiv-infected-individuals
#2
Juan Ambrosioni, Mar Mosquera, José M Miró
No abstract text is available yet for this article.
December 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30520987/inflammatory-and-infectious-syndromes-associated-with-cancer-immunotherapies
#3
Jay A Fishman, John I Hogan, Marcela V Maus
Immunotherapy using antibodies to immune checkpoint molecules or targeted chimeric antigen receptor-modified T (CAR-T) cells represent dramatic advances in cancer treatment. These therapies mediate immune-related adverse events (irAEs) which may mimic or amplify infectious presentations. Checkpoint inhibitor therapy may be associated with diverse irAEs including mild skin, endocrine and autoimmune manifestations or severe inflammatory processes including colitis, pneumonitis, myocarditis, and shock. CAR-T-cell therapies may induce toxicities including Cytokine-Release Syndrome (CRS) with fevers and multiorgan dysfunction, CAR-T-cell-related encephalopathy syndrome (CRES) with altered mental status and neurologic dysfunction, or Hemophagocytic Lymphohistiocytosis-Macrophage-Activation Syndrome (HLH/MAS)...
December 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30520971/prevalence-of-human-papillomavirus-hiv-and-other-sexually-transmitted-infections-among-men-having-sex-with-men-in-togo-a-national-cross-sectional-survey
#4
Valentine Marie Ferré, Fifonsi A Gbeasor-Komlanvi, Gilles Collin, Anoumou Claver Dagnra, Quentin Le Hingrat, Antoine Jaquet, Mounerou Salou, Diane Descamps, Charlotte Charpentier, Didier Koumavi Ekouevi
Background: Sub-Saharan Africa is a region of both high HIV and anal cancer incidence. We conducted the first national study in Togo to assess HPV, HIV and other Sexually Transmitted Infections (STIs) prevalence among Men having Sex with Men (MSM). Methods: A multicentric cross-sectional study was conducted among MSM recruited in four Togolese cities based on the respondent-driven sampling method. Socio-demographic characteristics and sexual behaviors were recorded using a standardized questionnaire...
December 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30517612/performance-of-stool-testing-recommendations-for-acute-gastroenteritis-when-used-to-identify-children-with-nine-potential-bacterial-enteropathogens
#5
Gillian A M Tarr, Linda Chui, Bonita E Lee, Xiao-Li Pang, Samina Ali, Alberto Nettel-Aguirre, Otto G Vanderkooi, Byron M Berenger, James Dickinson, Phillip I Tarr, Steven Drews, Judy MacDonald, Kelly Kim, Stephen B Freedman
Background: The ability to identify bacterial pathogens that necessitate specific clinical management or public health action in children with acute gastroenteritis is crucial to patient care and public health. However, existing stool testing guidelines offer inconsistent recommendations, and their performance characteristics are unknown. We evaluated six leading gastroenteritis guidelines (e.g. those of the Centers for Disease Control and Prevention and Infectious Disease Society of America) that recommend when to test children's stool for bacterial enteropathogens...
December 4, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30517592/impact-of-a-prescriber-driven-antibiotic-time-out-on-antibiotic-use-in-hospitalized-patients
#6
Kerri A Thom, Pranita D Tamma, Anthony D Harris, Kathryn Dzintars, Daniel J Morgan, Shanshan Li, Lisa Pineles, Arjun Srinivasan, Edina Avdic, Sara E Cosgrove
A multicenter quasi-experimental study of a provider-driven antibiotic "time-out" in 3470 antibiotic courses showed no difference in antibiotic use before and after implementation, but did show a decrease in inappropriate therapy (45% vs 31%, P < .05). Single time-outs without input from antibiotic stewardship teams are insufficient to optimize prescribing.
December 4, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30508064/the-impact-of-prior-season-vaccination-on-subsequent-influenza-vaccine-effectiveness-ve-to-prevent-influenza-related-hospitalizations-over-four-influenza-seasons-in-canada
#7
M K Nichols, M K Andrew, L Ye, T F Hatchette, A Ambrose, G Boivin, W Bowie, G Dos Santos, M Elsherif, K Green, F Haguinet, K Katz, J Leblanc, M Loeb, D MacKinnon-Cameron, A McCarthy, J E McElhaney, A McGeer, J Powis, D Richardson, M Semret, R Sharma, V Shinde, D Smyth, S Trottier, L Valiquette, D Webster, S A McNeil
Background: Recent studies have demonstrated the possibility of negative associations between prior influenza vaccines and subsequent influenza vaccine effectiveness (VE), depending on season and strain. We investigated this association over 4 consecutive influenza seasons (2011/2012-2014/2015) in Canada. Methods: Using a matched test-negative design, laboratory-confirmed influenza cases and matched test-negative controls admitted to hospitals were enrolled. Patients were stratified into four groups according to influenza vaccine history (not vaccinated current and prior season [referent], vaccinated prior season only, vaccinated current season only, and vaccinated both current and prior season)...
December 3, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30508065/quantifying-how-different-clinical-presentations-levels-of-severity-and-healthcare-attendance-shape-the-burden-of-influenza-associated-illness-a-modeling-study-from-south-africa
#8
Stefano Tempia, Sibongile Walaza, Jocelyn Moyes, Adam L Cohen, Meredith L McMorrow, Florette K Treurnicht, Orienka Hellferscee, Nicole Wolter, Anne von Gottberg, Arthemon Nguweneza, Johanna M McAnerney, Halima Dawood, Ebrahim Variava, Shabir A Madhi, Cheryl Cohen
Background: Burden estimates of medically- and non-medically-attended influenza-associated illness across syndromes and levels of severity are lacking. Methods: We estimated the national burden of medically- and non-medically-attended influenza-associated illness among individuals with different clinical presentations (all-respiratory, all-circulatory and non-respiratory/non-circulatory) and levels of severity (mild, severe-non-fatal and fatal) using a combination of case-based (from laboratory-confirmed influenza surveillance) and ecological studies as well as data from healthcare utilization surveys in South Africa during 2013-2015...
December 2, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30508036/metagenomic-virome-sequencing-in-living-donor-recipient-kidney-transplant-pairs-revealed-jc-polyomavirus-transmission
#9
Peter W Schreiber, Verena Kufner, Kerstin Hübel, Stefan Schmutz, Osvaldo Zagordi, Amandeep Kaur, Cornelia Bayard, Michael Greiner, Andrea Zbinden, Riccarda Capaul, Jürg Böni, Hans H Hirsch, Thomas F Mueller, Nicolas J Mueller, Alexandra Trkola, Michael Huber
Background: Before kidney transplantation, donors and recipients are routinely screened for viral pathogens using specific tests. Little is known about unrecognized viruses of the urinary tract that potentially result in transmission. Using an open metagenomic approach, we aimed to comprehensively assess virus transmission in living donor kidney transplantation. Methods: Living kidney donors and their corresponding recipients were enrolled at the time of transplantation...
December 2, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30517606/reply-to-bouiller-et-al-and-to-lacout-et-al
#10
Elie Haddad, Eric Caumes
No abstract text is available yet for this article.
November 30, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30517603/respiratory-syncytial-virus-prophylaxis-in-infants-with-congenital-diaphragmatic-hernia-in-the-caress-registry-2005-2017
#11
Doyoung Kim, Mahwesh Saleem, Bosco Paes, Ian Mitchell, Krista L Lanctôt
Background: Infants with congenital diaphragmatic hernia (CDH) are at increased risk of respiratory morbidity from recurrent respiratory tract infections including those from respiratory syncytial virus (RSV). Data from prospective studies on RSV prophylaxis in CDH infants are limited. The objective was to determine the risk of respiratory illness- and RSV-related hospitalizations (RIH and RSVH, respectively) among infants prophylaxed for CDH, standard indications (SI), and those without increased risk (NR)...
November 30, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30496366/the-epidemiology-of-herpes-zoster-in-the-united-states-during-the-era-of-varicella-and-herpes-zoster-vaccines-changing-patterns-among-children
#12
Rafael Harpaz, Jessica W Leung
Varicella vaccination can have complex direct and indirect influences on the epidemiology of herpes zoster among children. We evaluated pediatric herpes zoster trends using administrative databases. Incidence declined in a step-wise pattern since the varicella vaccination program was introduced, suggesting that rates may eventually decline in the entire population.
November 29, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30496358/the-epidemiology-of-herpes-zoster-in-the-united-states-during-the-era-of-varicella-and-herpes-zoster-vaccines-changing-patterns-among-older-adults
#13
Rafael Harpaz, Jessica W Leung
Historic herpes zoster incidence trends in US adults have been hard to interpret. Using administrative databases, we extended previous descriptions of these trends through 2016. We observed an age-specific transition, with ongoing increases among younger adults but deceleration in older adults. The patterns are not readily explained.
November 29, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30496356/erratum
#14
(no author information available yet)
No abstract text is available yet for this article.
November 29, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30496350/efficacy-and-safety-of-ascending-dosages-of-tribendimidine-against-hookworm-infections-in-children-a-randomized-controlled-trial
#15
Jean T Coulibaly, Noemi Hiroshige, Yves K N'Gbesso, Jan Hattendorf, Jennifer Keiser
Background: The global strategy to control soil-transmitted helminthiasis is mainly focused on preventive chemotherapy based on albendazole and mebendazole. We assessed the efficacy and safety of ascending tribendimidine doses against hookworm infections in African school-aged children, key information to be able to include tribendimidine in preventive deworming campaigns. Methods: We performed a single blind randomized controlled trial in Côte d'Ivoire between June and August 2017...
November 29, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30517601/the-potential-of-laiv-for-the-prevention-of-influenza-in-children
#16
Robert B Belshe
No abstract text is available yet for this article.
November 27, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30481273/prevalence-and-determinants-of-quantiferon-diagnosed-tuberculosis-infection-in-9-810-mongolian-schoolchildren
#17
Davaasambuu Ganmaa, Polyna Khudyakov, Uyanga Buyanjargal, Badamtsetseg Jargalsaikhan, Delgerekh Baigal, Oyunsuren Munkhjargal, Narankhuu Yansan, Sunjidmaa Bolormaa, Enkhsaikhan Lkhagvasuren, Christopher T Sempos, Sabri Bromage, Zhenqiang Wu, Batbayar Ochirbat, Batbaatar Gunchin, Adrian R Martineau
Background: There is controversy regarding the potential influence of vitamin D deficiency, exposure to environmental tobacco smoke, BCG vaccination, season and body habitus on susceptibility to Mycobacterium tuberculosis (MTB) infection. Methods: We conducted a cross-sectional analysis to identify determinants of a positive QuantiFERON®-TB Gold (QFT) assay result in children aged 6-13 years attending 18 schools in Ulaanbaatar, Mongolia. Data relating to potential risk factors for MTB infection were collected by questionnaire, physical examination and determination of serum 25-hydroxyvitamin D (25[OH]D) concentrations...
November 27, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30481272/a-canopy-conundrum-can-wind-induced-movement-help-to-increase-crop-productivity-by-relieving-photosynthetic-limitations
#18
Alexandra J Burgess, Jonathon A Gibbs, Erik H Murchie
Wind-induced movement is a ubiquitous occurrence for all plants grown in natural or agricultural settings and in the context of high, damaging wind speeds it has been well studied. However, the impact of lower wind speeds (that do not cause any damage) on mode of movement, light transmission and photosynthetic properties has, surprisingly, not been fully explored. This is likely to be influenced by biomechanical properties and architectural features of the plant and canopy. A limited number of eco-physiological studies have indicated that movement in wind has the potential to alter light distribution within canopies, improving canopy productivity by relieving photosynthetic limitations...
November 27, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30481269/the-effect-of-pre-existing-immunity-on-virus-detection-and-immune-responses-in-a-phase-ii-randomized-trial-of-a-russian-backbone-live-attenuated-influenza-vaccine-in-bangladeshi-children
#19
Elizabeth B Brickley, Peter F Wright, Alexey Khalenkov, Kathleen M Neuzil, Justin R Ortiz, Larisa Rudenko, Min Z Levine, Jacqueline M Katz, W Abdullah Brooks
Background: In a 2012 phase II clinical trial (NCT01625689), 300 Bangladeshi children aged 24 to 59 months with no prior influenza vaccine exposure were randomized to receive a single dose of intra-nasally administered trivalent Russian-backbone live attenuated influenza vaccine (LAIV) or placebo. Protocol-defined analyses, presented in the companion manuscript, demonstrate decreased viral detection and immunogenicity for A/H1N1pdm09 relative to the A/H3N2 and B strains. This post-hoc analysis of the trial data aims to investigate the LAIV strain differences by testing the hypothesis that pre-existing immunity may influence viral recovery and immune responses after LAIV receipt...
November 27, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30476007/hiv-1-transmission-among-persons-with-acute-hiv-1-infection-in-malawi-demographic-behavioral-and-phylogenetic-relationships
#20
Ann M Dennis, Myron S Cohen, Katherine B Rucinski, Sarah E Rutstein, Kimberly A Powers, Dana K Pasquale, Sam Phiri, Mina C Hosseinipour, Gift Kamanga, Dominic Nsona, Cecilia Massa, Irving F Hoffman, Audrey E Pettifor, William C Miller
Background: Understanding of sexual networks involving acute HIV-1 infections (AHI) may lead to prevention opportunities to mitigate high rates of onward transmission. We evaluated HIV-1 phylogenetic and behavioral characteristics among persons with AHI and their referred partners. Methods: Between 2012 and 2014, 46 persons with AHI in Malawi participated in a combined behavioral and biomedical intervention. Participants referred sexual partners for HIV-1 testing by passive referral...
November 26, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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