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Anesthesiology

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https://www.readbyqxmd.com/read/29329122/some-of-us-stay
#1
Rebekka DePew
No abstract text is available yet for this article.
January 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29324485/bearing-witness-to-anger-and-loss
#2
Suzanne Crowe
No abstract text is available yet for this article.
January 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29324484/fear-in-perspective
#3
Mary F Chisholm
No abstract text is available yet for this article.
January 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29324483/advancing-patient-safety-in-airway-management
#4
Michael F Aziz
No abstract text is available yet for this article.
January 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29324482/enhanced-needle-visibility-by-micro-air-bubble-contrast-in-ultrasound-guided-nerve-block
#5
Yong Liu, Wei Mei
No abstract text is available yet for this article.
January 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29324481/do-anesthetic-choices-signal-quality
#6
Catherine L Chen, Mark D Neuman
No abstract text is available yet for this article.
January 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29324480/anesthesiology-board-certification-changes-a-real-time-example-of-assessment-drives-learning
#7
David J Murray, John R Boulet
No abstract text is available yet for this article.
January 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29309282/utility-of-perioperative-lung-ultrasound-in-pediatric-cardiac-surgery-a-randomized-controlled-trial
#8
In-Kyung Song, Eun-Hee Kim, Ji-Hyun Lee, Pyoyoon Kang, Hee-Soo Kim, Jin-Tae Kim
BACKGROUND: Pediatric cardiac patients are at risk for perioperative respiratory insufficiency. The objective of this study was to assess the utility of perioperative lung ultrasound examination in pediatric cardiac surgery. METHODS: In this randomized, controlled trial, children (5 yr old or younger) undergoing cardiac surgery were allocated into a control (n = 61) or intervention (n = 61) group. The control group received only lung ultrasound examinations at the end of surgery and 6 to 12 h after surgery...
January 8, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29303790/relaxation-before-debriefing-during-high-fidelity-simulation-improves-memory-retention-of-residents-at-three-months-a-prospective-randomized-controlled-study
#9
Marc Lilot, Jean-Noel Evain, Christian Bauer, Jean-Christophe Cejka, Alexandre Faure, Baptiste Balança, Olivia Vassal, Cécile Payet, Bernard Bui Xuan, Antoine Duclos, Jean-Jacques Lehot, Thomas Rimmelé
BACKGROUND: High-fidelity simulation is known to improve participant learning and behavioral performance. Simulation scenarios generate stress that affects memory retention and may impact future performance. The authors hypothesized that more participants would recall three or more critical key messages at three months when a relaxation break was performed before debriefing of critical event scenarios. METHODS: Each resident actively participated in one scenario and observed another...
January 5, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29303789/sevoflurane-blocks-the-induction-of-long-term-potentiation-when-present-during-but-not-when-present-only-before-the-high-frequency-stimulation
#10
Jinyang Liu, Lie Yang, Daisy Lin, James E Cottrell, Ira S Kass
BACKGROUND: This study tests the hypothesis that sevoflurane blocks long-term potentiation only if it is present during the high-frequency stimulation that induces long-term potentiation. METHODS: Long-term potentiation, an electrophysiologic correlate of memory, was induced by high-frequency stimulation and measured as a persistent increase in the field excitatory postsynaptic potential slope in the CA1 region. RESULTS: Long-term potentiation was induced in the no sevoflurane group (171 ± 58% vs...
January 5, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29278533/a-clogged-dialysis-filter-caused-by-severe-acutely-induced-hypertriglyceridemia
#11
Ricardo Diaz Milian, Roberto Diaz Galdo, Manuel R Castresana
No abstract text is available yet for this article.
December 26, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29271804/exposure-of-developing-brain-to-general-anesthesia-what-is-the-animal-evidence
#12
Vesna Jevtovic-Todorovic
Recently, the U.S. Food and Drug Administration issued an official warning to all practicing physicians regarding potentially detrimental behavioral and cognitive sequelae of an early exposure to general anesthesia during in utero and in early postnatal life. The U.S. Food and Drug Administration concern is focused on children younger than three years of age who are exposed to clinically used general anesthetics and sedatives for three hours or longer. Although human evidence is limited and controversial, a large body of scientific evidence gathered from several mammalian species demonstrates that there is a potential foundation for concern...
December 22, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29271803/transcriptional-changes-in-dorsal-spinal-cord-persist-after-surgical-incision-despite-preemptive-analgesia-with-peripheral-resiniferatoxin
#13
Stephen J Raithel, Matthew R Sapio, Danielle M LaPaglia, Michael J Iadarola, Andrew J Mannes
BACKGROUND: Peripheral nociceptors expressing the ion channel transient receptor potential cation channel, subfamily V, member 1, play an important role in mediating postoperative pain. Signaling from these nociceptors in the peri- and postoperative period can lead to plastic changes in the spinal cord and, when controlled, can yield analgesia. The transcriptomic changes in the dorsal spinal cord after surgery, and potential coupling to transient receptor potential cation channel, subfamily V, member 1-positive nociceptor signaling, remain poorly studied...
December 22, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29252510/astrocytic-n-myc-downstream-regulated-gene-2-is-involved-in-nuclear-transcription-factor-%C3%AE%C2%BAb-mediated-inflammation-induced-by-global-cerebral-ischemia
#14
You-Liang Deng, Yu-Long Ma, Zeng-Li Zhang, Li-Xia Zhang, Hang Guo, Pei Qin, Yu-Shu Hou, Zi-Jun Gao, Wu-Gang Hou
BACKGROUND: Inflammation is a key element in the pathophysiology of cerebral ischemia. This study investigated the role of N-Myc downstream-regulated gene-2 in nuclear transcription factor κB-mediated inflammation in ischemia models. METHODS: Mice (n = 6 to 12) with or without nuclear transcription factor κB inhibitor pyrrolidinedithiocarbamate pretreatment were subjected to global cerebral ischemia for 20 min. Pure astrocyte cultures or astrocyte-neuron cocultures (n = 6) with or without pyrrolidinedithiocarbamate pretreatment were exposed to oxygen-glucose deprivation for 4 h or 2 h...
December 18, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29252509/dexmedetomidine-prevents-cognitive-decline-by-enhancing-resolution-of-high-mobility-group-box-1-protein-induced-inflammation-through-a-vagomimetic-action-in-mice
#15
Jun Hu, Susana Vacas, Xiaomei Feng, David Lutrin, Yosuke Uchida, Ieng Kit Lai, Mervyn Maze
BACKGROUND: Inflammation initiated by damage-associated molecular patterns has been implicated for the cognitive decline associated with surgical trauma and serious illness. We determined whether resolution of inflammation mediates dexmedetomidine-induced reduction of damage-associated molecular pattern-induced cognitive decline. METHODS: Cognitive decline (assessed by trace fear conditioning) was induced with high molecular group box 1 protein, a damage-associated molecular pattern, in mice that also received blockers of neural (vagal) and humoral inflammation-resolving pathways...
December 18, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29252508/abuse-deterrent-opioid-formulations
#16
Ronald S Litman, Olivia H Pagán, Theodore J Cicero
Abuse-deterrent opioid formulations have been suggested as one way to decrease the abuse, addiction, and overdose of orally prescribed opioids. Ten oral opioid formulations have received abuse-deterrent labeling by the U.S. Food and Drug Administration (FDA). Their properties consist of physical and/or chemical means by which the pills resist manipulation and create a barrier to unintended administration, such as chewing, nasal snorting, smoking, and intravenous injection. In this review, we describe the mechanisms of abuse-deterrent technology, the types of premarketing studies required for FDA approval, the pharmacology of the currently approved abuse-deterrent opioid formulations, and the evidence for and against their influence on opioid abuse...
December 18, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29251646/use-of-uncrossmatched-erythrocytes-in-emergency-bleeding-situations
#17
Mark H Yazer, Jonathan H Waters, Philip C Spinella, Col Andrew Cap, Capt Roland L Fahie, Emmett Gourdine, Donald H Jenkins, Steven Kleinman, Ernest E Moore, Paul Ness, Eilat Shinar, Steve R Sloan, James R Stubbs, Kevin R Ward
No abstract text is available yet for this article.
December 15, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29251645/dopamine-d2-receptor-antagonist-droperidol-deepens-sevoflurane-anesthesia
#18
Ryuhei Araki, Kazuko Hayashi, Teiji Sawa
BACKGROUND: Although midbrain dopaminergic pathways are known to contribute to arousal and emergence from anesthesia, few reports exist regarding the anesthetic effects of dopamine D2 receptor antagonism in humans. This study examined the effect of the D2 receptor antagonist droperidol on sevoflurane anesthesia by examining α and slow wave electroencephalogram oscillations. METHODS: Forty-five patients, age 20 to 60 yr, were enrolled. Frontal electroencephalograms were continuously collected for offline analysis via Bispectral Index monitoring...
December 15, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29251644/pharmacodynamics-and-pharmacokinetics-of-lidocaine-in-a-rodent-model-of-diabetic-neuropathy
#19
Werner Ten Hoope, Markus W Hollmann, Kora de Bruin, Hein J Verberne, Arie O Verkerk, Hanno L Tan, Camiel Verhamme, Janneke Horn, Marcel Rigaud, Susanne Picardi, Philipp Lirk
BACKGROUND: Clinical and experimental data show that peripheral nerve blocks last longer in the presence of diabetic neuropathy. This may occur because diabetic nerve fibers are more sensitive to local anesthetics or because the local anesthetic concentration decreases more slowly in the diabetic nerve. The aim of this study was to investigate both hypotheses in a rodent model of neuropathy secondary to type 2 diabetes. METHODS: We performed a series of sciatic nerve block experiments in 25 Zucker Diabetic Fatty rats aged 20 weeks with a neuropathy component confirmed by neurophysiology and control rats...
December 15, 2017: Anesthesiology
https://www.readbyqxmd.com/read/29251643/then-it-was-dark-and-cold
#20
Jay Harnden
No abstract text is available yet for this article.
December 15, 2017: Anesthesiology
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