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Anesthesiology

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https://www.readbyqxmd.com/read/28212206/three-wise-men-%C3%A3-2-and-the-asa-physical-status-classification-system
#1
BobbieJean Sweitzer
No abstract text is available yet for this article.
February 17, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28212205/spontaneous-breathing-during-extracorporeal-membrane-oxygenation-in-acute-respiratory-failure
#2
Stefania Crotti, Nicola Bottino, Giulia Maria Ruggeri, Elena Spinelli, Daniela Tubiolo, Alfredo Lissoni, Alessandro Protti, Luciano Gattinoni
BACKGROUND: We evaluate the clinical feasibility of spontaneous breathing on extracorporeal membrane oxygenation and the interactions between artificial and native lungs in patients bridged to lung transplant or with acute exacerbation of chronic obstructive pulmonary disease (COPD) or acute respiratory distress syndrome. METHODS: The clinical course of a total of 48 patients was analyzed. Twenty-three of 48 patients were enrolled in the prospective study (nine bridged to lung transplant, six COPD, and eight acute respiratory distress syndrome)...
February 17, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28212204/1-2-4-dibromophenyl-3-6-6-trimethyl-1-5-6-7-tetrahydro-4h-indazol-4-one-a-novel-opioid-receptor-agonist-with-less-accompanying-gastrointestinal-dysfunction-than-morphine
#3
Po-Kuan Chao, Shau-Hua Ueng, Li-Chin Ou, Teng-Kuang Yeh, Wan-Ting Chang, Hsiao-Fu Chang, Shu-Chun Chen, Pao-Luh Tao, Ping-Yee Law, Horace H Loh, Ming-Fu Cheng, Jian-Ying Chuang, Chiung-Tong Chen, Chuan Shih, Shiu-Hwa Yeh
BACKGROUND: The authors investigated the pharmacology and signaling pathways of the opioid receptors modulated by compound 1, 1-(2,4-dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one. METHODS: In vitro studies of compound 1 were assessed by using a radioligand-binding assay (n = 3), a cyclic adenosine monophosphate assay (n = 3), a β-arrestin assay (n = 3), an internalization assay (n = 3), and an immunohistochemistry (n = 8). In vivo studies of compound 1 were characterized using a tail-flick test (n = 5 to 6), tail-clip test (n = 7), von Frey hair test (n = 5), and charcoal meal test (n = 5)...
February 17, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28212203/adding-examples-to-the-asa-physical-status-classification-improves-correct-assignment-to-patients
#4
Erin E Hurwitz, Michelle Simon, Sandhya R Vinta, Charles F Zehm, Sarah M Shabot, Abu Minhajuddin, Amr E Abouleish
BACKGROUND: Despite its widespread use, the American Society of Anesthesiologists (ASA)-Physical Status Classification System has been shown to result in inconsistent assignments among anesthesiologists. The ASA-Physical Status Classification System is also used by nonanesthesia-trained clinicians and others. In 2014, the ASA developed and approved examples to assist clinicians in determining the correct ASA-Physical Status Classification System assignment. The effect of these examples by anesthesia-trained and nonanesthesia-trained clinicians on appropriate ASA-Physical Status Classification System assignment in hypothetical cases was examined...
February 17, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28207437/lack-of-association-between-preoperative-statin-use-and-respiratory-and-neurologic-complications-after-cardiac-surgery
#5
Ryu Komatsu, Huseyin Oguz Yilmaz, Jing You, C Allen Bashour, Shobana Rajan, Edward G Soltesz, Daniel I Sessler, Alparslan Turan
BACKGROUND: Statins may reduce the risk of pulmonary and neurologic complications after cardiac surgery. METHODS: The authors acquired data for adults who had coronary artery bypass graft, valve surgery, or combined procedures. The authors matched patients who took statins preoperatively to patients who did not. First, the authors assessed the association between preoperative statin use and the primary outcomes of prolonged ventilation (more than 24 h), pneumonia (positive cultures of sputum, transtracheal fluid, bronchial washings, and/or clinical findings consistent with the diagnosis of pneumonia), and in-hospital all-cause mortality, using logistic regressions...
February 16, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28187023/validation-and-calibration-of-the-risk-stratification-index
#6
George F Chamoun, Linyan Li, Nassib G Chamoun, Vikas Saini, Daniel I Sessler
BACKGROUND: The Risk Stratification Index was developed from 35 million Medicare hospitalizations from 2001 to 2006 but has yet to be externally validated on an independent large national data set, nor has it been calibrated. Finally, the Medicare Analysis and Provider Review file now allows 25 rather than 9 diagnostic codes and 25 rather than 6 procedure codes and includes present-on-admission flags. The authors sought to validate the index on new data, test the impact of present-on-admission codes, test the impact of the expansion to 25 diagnostic and procedure codes, and calibrate the model...
February 10, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28187022/carotid-body-paraganglioma-a-rare-tumor-with-serious-anesthetic-challenges
#7
Angela T Truong, Sudip Thakar, Dam-Thuy Truong
No abstract text is available yet for this article.
February 10, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28187021/on-the-road-to-professionalism
#8
David H Chestnut
Many observers have concluded that we have a crisis of professionalism in the practice of medicine. In this essay, the author identifies and discusses personal attributes and commitments important in the development and maintenance of physician professionalism: humility, servant leadership, self-awareness, kindness, altruism, attention to personal well-being, responsibility and concern for patient safety, lifelong learning, self-regulation, and honesty and integrity. Professionalism requires character, but character alone is not enough...
February 10, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28187020/torus-palatinus-and-airway-management
#9
Jesse Aron, Stephen J Raithel, Andrew J Mannes
No abstract text is available yet for this article.
February 10, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28187019/persistent-left-superior-vena-cava-unusual-catheter-position-on-chest-x-ray-film
#10
Ranjit Deshpande, Matthew Band, Viji Kurup
No abstract text is available yet for this article.
February 10, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28187018/anomalous-single-coronary-artery-from-the-pulmonary-artery
#11
Kelly A Machovec, Brad Taicher, Robert D B Jaquiss, Kevin D Hill
No abstract text is available yet for this article.
February 10, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28182586/anesthetic-neuroprotection-it-s-complicated
#12
David S Warner, Huaxin Sheng
No abstract text is available yet for this article.
February 9, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28182585/anesthetic-neuroprotection-in-experimental-stroke-in-rodents-a-systematic-review-and-meta-analysis
#13
David P Archer, Andrew M Walker, Sarah K McCann, Joanna J Moser, Ramana M Appireddy
BACKGROUND: Patients undergoing endovascular therapy for acute ischemic stroke may require general anesthesia to undergo the procedure. At present, there is little clinical evidence to guide the choice of anesthetic in this acute setting. The clinical implications of experimental studies demonstrating anesthetic neuroprotection are poorly understood. Here, the authors evaluated the impact of anesthetic treatment on neurologic outcome in experimental stroke. METHODS: Controlled studies of anesthetics in stroke using the filament occlusion model were identified in electronic databases up to December 15, 2015...
February 9, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28182584/impact-of-pain-on-incident-risk-of-disability-in-elderly-japanese-cause-specific-analysis
#14
Yu Kaiho, Yumi Sugawara, Kemmyo Sugiyama, Yasutake Tomata, Yasuhiro Endo, Hiroaki Toyama, Masanori Yamauchi, Ichiro Tsuji
BACKGROUND: Although several cross-sectional studies have reported that pain is associated with functional disability in the elderly, data regarding a longitudinal association between pain and disability are inconsistent. This study aimed to investigate the association of pain severity with subsequent functional disability due to all causes as well as stroke, dementia, and joint disease/fracture. METHODS: The authors conducted a prospective cohort study of 13,702 Japanese individuals aged 65 yr or older...
February 9, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28169844/standard-setting-for-clinical-performance-of-basic-perioperative-transesophageal-echocardiography-moving-beyond-the-written-test
#15
Julian S Bick, Jonathan P Wanderer, Conrad S Myler, Andrew D Shaw, Matthew D McEvoy
BACKGROUND: Credible methods for assessing competency in basic perioperative transesophageal echocardiography examinations have not been reported. The authors' objective was to demonstrate the collection of real-world basic perioperative transesophageal examination performance data and establish passing scores for each component of the basic perioperative transesophageal examination, as well as a global passing score for clinical performance of the basic perioperative transesophageal examination using the Angoff method...
February 7, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28169843/a-road-map-to-assess-clinical-competency-in-basic-transesophageal-echocardiography
#16
Nikolaos J Skubas
No abstract text is available yet for this article.
February 7, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28166110/high-sensitivity-cardiac-troponin-elevation-after-electroconvulsive-therapy-a-prospective-observational-cohort-study
#17
Andreas Duma, Swatilika Pal, Joshua Johnston, Mohammad A Helwani, Adithya Bhat, Bali Gill, Jessica Rosenkvist, Christopher Cartmill, Frank Brown, J Philip Miller, Mitchell G Scott, Francisco Sanchez-Conde, Michael Jarvis, Nuri B Farber, Charles F Zorumski, Charles Conway, Peter Nagele
BACKGROUND: While electroconvulsive therapy is widely regarded as a lifesaving and safe procedure, evidence regarding its effects on myocardial cell injury is sparse. The objective of this investigation was to determine the incidence and magnitude of new cardiac troponin elevation after electroconvulsive therapy using a novel high-sensitivity cardiac troponin I assay. METHODS: This was a prospective cohort study in adult patients undergoing electroconvulsive therapy in a single academic center (up to three electroconvulsive therapy treatments per patient)...
February 6, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28157135/hospital-experience-caring-for-the-frail-a-new-concern-for-surgical-patients
#18
Han Ting Wang, Hannah Wunsch
No abstract text is available yet for this article.
February 3, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28157134/association-of-the-hospital-volume-of-frail-surgical-patients-cared-for-with-outcomes-after-elective-major-noncardiac-surgery-a-retrospective-population-based-cohort-study
#19
Daniel I McIsaac, Duminda N Wijeysundera, Allen Huang, Gregory L Bryson, Carl van Walraven
BACKGROUND: Frailty is a risk factor for adverse postoperative outcomes. Hospitals that perform higher volumes of surgery have better outcomes than low-volume providers. We hypothesized that frail patients undergoing elective surgery at hospitals that cared for a higher volume of similarly frail patients would have improved outcomes. METHODS: We conducted a retrospective, population-based cohort study using linked administrative data in Ontario, Canada. We identified all adult major, elective noncardiac surgery patients who were frail according to the validated Johns Hopkins Adjusted Clinical Groups (ACG) frailty-defining diagnoses indicator...
February 3, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28121635/lidocaine-induces-apoptosis-and-suppresses-tumor-growth-in-human-hepatocellular-carcinoma-cells-in-vitro-and-in-a-xenograft-model-in-vivo
#20
Wei Xing, Dong-Tai Chen, Jia-Hao Pan, Yong-Hua Chen, Yan Yan, Qiang Li, Rui-Feng Xue, Yun-Fei Yuan, Wei-An Zeng
BACKGROUND: Recent epidemiologic studies have focused on the potential beneficial effects of regional anesthetics, and the differences in cancer prognosis may be the result of anesthetics on cancer biologic behavior. However, the function and underlying mechanisms of lidocaine in hepatocellular carcinoma both in vitro and in vivo have been poorly studied. METHODS: Human HepG2 cells were treated with lidocaine. Cell viability, colony formation, cell cycle, and apoptosis were assessed...
January 25, 2017: Anesthesiology
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