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Anesthesiology

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https://www.readbyqxmd.com/read/30222600/measuring-clinical-productivity-of-anesthesiology-groups-surgical-anesthesia-at-the-facility-level
#1
Amr E Abouleish, Mark E Hudson, Charles W Whitten
Benchmarking and comparing group productivity is an essential activity of data-driven management. For clinical anesthesiology, accomplishing this task is a daunting effort if meaningful conclusions are to be made. For anesthesiology groups, productivity must be done at the facility level in order to reduce some of the confounding factors. When industry or external comparisons are done, then the use of total ASA units per anesthetizing sites allows for overall productivity comparisons. Additional productivity components (total ASA units/h, h/case, h/operating room/d) allow for leaders to develop productivity dashboards...
September 17, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30222602/inadvertent-extracorporeal-membrane-oxygenation-cannulation-across-a-patent-foramen-ovale
#2
Jose R Navas-Blanco, Derrick V Williams
No abstract text is available yet for this article.
September 14, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30222601/succinylcholine-and-intracranial-pressure
#3
James E Cottrell
Intracranial and Hemodynamic Changes after Succinylcholine Administration in Cats. By Cottrell JE, Hartung J, Giffin JP, and Shwiry B. Anesthesia & Analgesia 1983; 62:1006-9. Reprinted with permission.Bolus injections of succinylcholine (1.5 mg/kg) significantly increased intracranial pressure (ICP) in cats under normal conditions from control levels of 8 +/- 1 mmHg to 16 +/- 3 mmHg (+/- SEM, P less than 0.01), and in the presence of artificially increased ICP from control levels of 27 +/- 1 mmHg to 47 +/- 4 mmHg (P less than 0...
September 14, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30212413/preclinical-pharmacology-in-the-rhesus-monkey-of-cw-1759-50-a-new-ultra-short-acting-nondepolarizing-neuromuscular-blocking-agent-degraded-and-antagonized-by-l-cysteine
#4
John J Savarese, Hiroshi Sunaga, Jeff D McGilvra, Matthew R Belmont, Matthew T Murrell, Erin Jeannotte, Farrell E Cooke, William B Wastila, Paul M Heerdt
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Structure-activity studies were performed to identify a new neuromuscular blocking agent retaining the ultra-short acting characteristics of gantacurium, including degradation and reversal by L-cysteine, but lacking its histaminoid properties in man. CW 1759-50 has emerged from this program. METHODS: Adduction of CW 1759-50 with L-cysteine was studied by high-performance liquid chromatography and mass spectrometry...
September 13, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30212412/morbidity-and-mortality-of-crystalloids-compared-to-colloids-in-critically-ill-surgical-patients-a-subgroup-analysis-of-a-randomized-trial
#5
Nicholas Heming, Laure Lamothe, Samir Jaber, Jean Louis Trouillet, Claude Martin, Sylvie Chevret, Djillali Annane
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: The multicenter randomized Colloids versus Crystalloids for the Resuscitation of the Critically Ill (CRISTAL) trial was designed to test whether colloids altered mortality compared to crystalloids in the resuscitation of intensive care unit patients with hypovolemic shock. This preplanned analysis tested the same hypothesis in the subgroup of surgical patients. METHODS: The CRISTAL trial prospectively defined patients as critically ill surgical patients whenever they underwent emergency or scheduled surgery immediately before or within 24 h of intensive care unit admission and had hypovolemic shock...
September 13, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30204595/workflow-eats-optimum-care-for-lunch
#6
Warren S Sandberg, Sorin J Brull
No abstract text is available yet for this article.
September 11, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30204594/perioperative-hyperglycemia-management-an-update-erratum
#7
(no author information available yet)
No abstract text is available yet for this article.
September 11, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30204593/ultrasound-elastography-for-rapid-real-time-detection-of-localized-muscular-reaction-in-malignant-hyperthermia-susceptible-pigs
#8
Stephan Johannsen, Ismail Türkmeneli, Susanne Isbary, Norbert Roewer, Frank Schuster
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Halothane and caffeine induce excessive sarcoplasmic calcium liberation and skeletal muscle contracture in patients susceptible to malignant hyperthermia (MH) and are utilized for diagnosis in the in vitro contracture test. Intramuscular injection previously caused a marked local lactate increase in MH-susceptible but not in MH-nonsusceptible individuals in vivo. Using shear-wave elastography, this study evaluated localized changes in muscle stiffness after intramuscular injection of halothane and caffeine...
September 11, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30199420/brain-dynamics-and-temporal-summation-of-pain-predicts-neuropathic-pain-relief-from-ketamine-infusion
#9
Rachael L Bosma, Joshua C Cheng, Anton Rogachov, Junseok A Kim, Kasey S Hemington, Natalie R Osborne, Lakshmikumar Venkat Raghavan, Anuj Bhatia, Karen D Davis
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Ketamine is an N-methyl-D-aspartate receptor antagonist that reduces temporal summation of pain and modulates antinociception. Ketamine infusions can produce significant relief of neuropathic pain, but the treatment is resource intensive and can be associated with adverse effects. Thus, it is crucial to select patients who might benefit from this treatment. The authors tested the hypothesis that patients with enhanced temporal summation of pain and the capacity to modulate pain via the descending antinociceptive brain pathway are predisposed to obtain pain relief from ketamine...
September 7, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30199419/differences-of-recovery-from-rocuronium-induced-deep-paralysis-in-response-to-small-doses-of-sugammadex-between-elderly-and-nonelderly-patients
#10
Takahiro Muramatsu, Shiroh Isono, Teruhiko Ishikawa, Natsuko Nozaki-Taguchi, Junko Okazaki, Yuji Kitamura, Noriko Murakami, Yasunori Sato
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Complete recovery from rocuronium-induced muscle paralysis with sugammadex is reported to be delayed in elderly patients. The authors tested a hypothesis that recovery from deep neuromuscular block with low-dose sugammadex is slower (primary hypothesis) and incidence of recurarization is higher (secondary hypothesis) in elderly patients than in nonelderly patients. METHODS: In anesthetized elderly (n = 20; 76...
September 7, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30199418/caseous-calcification-of-the-mitral-annulus-mimic-and-malady
#11
Alexander D Shapeton, Abirami Kumaresan, David C Liu, Megan L Krajewski
No abstract text is available yet for this article.
September 7, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30192242/repair-of-a-giant-ascending-aortic-pseudoaneurysm-requiring-awake-institution-of-cardiopulmonary-bypass
#12
Sarah A Dunn, Oscar Aljure, Tomas Salerno, Yiliam F Rodriguez-Blanco
No abstract text is available yet for this article.
September 6, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30192241/blue-rubber-bleb-nevus-syndrome
#13
Cornelius A Sullivan
No abstract text is available yet for this article.
September 6, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30192240/preoperative-cardiac-evaluation-before-noncardiac-surgery-reverend-bayes-s-risk-indices-and-optimal-variables
#14
Lee A Fleisher
No abstract text is available yet for this article.
September 6, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30192239/double-chambered-right-ventricle
#15
John S McNeil, Jeffrey E Vergales, Allison J Bechtel, Amanda M Kleiman
No abstract text is available yet for this article.
September 6, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30169378/pulmonary-thromboembolism
#16
Denis H Jablonka, Abhay Srinivasan, Alan Jay Schwartz, Rajeev Subramanyam
No abstract text is available yet for this article.
August 31, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30161037/simultaneous-color-change-at-opposite-ends-of-carbon-dioxide-absorbent-canisters
#17
Robert G Loeb, Nikolaus Gravenstein
No abstract text is available yet for this article.
August 30, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30161036/profound-vasoconstriction-implications-for-percutaneous-arterial-access
#18
Daniel G Taylor, Luigi Camporota
No abstract text is available yet for this article.
August 30, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30157038/midazolam-and-dexmedetomidine-affect-neuroglioma-and-lung-carcinoma-cell-biology-in-vitro-and-in-vivo
#19
Chunyan Wang, Tanweer Datoo, Hailin Zhao, Lingzhi Wu, Akshay Date, Cui Jiang, Robert D Sanders, Guolin Wang, Charlotte Bevan, Daqing Ma
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Several factors within the perioperative period may influence postoperative metastatic spread. Dexmedetomidine and midazolam are widely used general anesthetics during surgery. The authors assessed their effects on human lung carcinoma (A549) and neuroglioma (H4) cell lines in vitro and in vivo. METHODS: Cell proliferation and migration were measured after dexmedetomidine (0...
August 29, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30157037/prothrombin-complex-concentrates-for-perioperative-vitamin-k-antagonist-and-non-vitamin-k-anticoagulant-reversal
#20
Jerrold H Levy, James Douketis, Thorsten Steiner, Joshua N Goldstein, Truman J Milling
Vitamin K antagonist therapy is associated with an increased bleeding risk, and clinicians often reverse anticoagulation in patients who require emergency surgical procedures. Current guidelines for rapid anticoagulation reversal for emergency surgery recommend four-factor prothrombin complex concentrate and vitamin K coadministration. The authors reviewed the current evidence on prothrombin complex concentrate treatment for vitamin K antagonist reversal in the perioperative setting, focusing on comparative studies and in the context of intracranial hemorrhage and cardiac surgery...
August 29, 2018: Anesthesiology
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