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Anesthesiology

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https://www.readbyqxmd.com/read/30418217/long-term-impact-of-crystalloid-versus-colloid-solutions-on-renal-function-and-disability-free-survival-after-major-abdominal-surgery
#1
Alexandre Joosten, Amélie Delaporte, Julien Mortier, Brigitte Ickx, Luc Van Obbergh, Jean-Louis Vincent, Maxime Cannesson, Joseph Rinehart, Philippe Van der Linden
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: The authors recently demonstrated that administration of balanced hydroxyethyl starch solution as part of intraoperative goal-directed fluid therapy was associated with better short-term outcomes than administration of a balanced crystalloid solution in patients having major open abdominal surgery. In the present study, a 1-yr follow-up of renal and disability outcomes in these patients was performed...
November 9, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30418213/low-incidence-of-biphasic-allergic-reactions-in-patients-admitted-to-intensive-care-after-anaphylaxis
#2
Sofie Højlund, Peter Søe-Jensen, Anders Perner, Morten H Bestle, Peder Carl, Katrin Thormar, Sandra Viggers, Sofie Elberling, Lene H Garvey
BACKGROUND: Biphasic allergic reactions-recurrence of allergy symptoms after a symptom-free period-are reported to occur in 1 to 23% of allergic reactions. Patients admitted to an intensive care unit after anaphylaxis potentially have more severe reactions and a higher risk of biphasic allergic reactions. The purpose of this study was to examine incidence, triggers, symptoms, and treatment of biphasic allergic reactions, in patients admitted to an intensive care unit. METHODS: Records of patients admitted to intensive care units with anaphylaxis from 2011 to 2014 were reviewed...
November 5, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30418212/contribution-of-baroreceptor-function-to-pain-perception-and-perioperative-outcomes
#3
Heberto Suarez-Roca, Rebecca Y Klinger, Mihai V Podgoreanu, Ru-Rong Ji, Martin I Sigurdsson, Nathan Waldron, Joseph P Mathew, William Maixner
Baroreceptors are mechanosensitive elements of the peripheral nervous system that maintain homeostasis by coordinating physiologic responses to external and internal stimuli. While it is recognized that carotid and cardiopulmonary baroreceptor reflexes modulate autonomic output to mitigate excessive fluctuations in arterial blood pressure and to maintain intravascular volume, increasing evidence suggests that baroreflex pathways also project to key regions of the central nervous system that regulate somatosensory, somatomotor, and central nervous system arousal...
November 5, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30418216/endovascular-retrieval-of-broken-arterial-cannulas
#4
Mathieu Béland, Catherine Lalonde, Guillaume Garneau, Mireille Méthot
No abstract text is available yet for this article.
November 2, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30418215/morphine-exacerbates-postfracture-nociceptive-sensitization-functional-impairment-and-microglial-activation-in-mice
#5
Wen-Wu Li, Karen-Amanda Irvine, Peyman Sahbaie, Tian-Zhi Guo, Xiao-You Shi, Vivianne L Tawfik, Wade S Kingery, J David Clark
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Emerging evidence suggests that opioid use immediately after surgery and trauma may worsen outcomes. In these studies, the authors aimed to determine whether morphine administered for a clinically relevant time period (7 days) in a tibia fracture orthopedic surgery model had adverse effects on postoperative recovery. METHODS: Mice were given morphine twice daily for 7 days after unilateral tibial fracture and intramedullary pin fixation to model orthopedic surgery and limb trauma...
November 2, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30418214/analgesic-effects-of-hydromorphone-versus-buprenorphine-in-buprenorphine-maintained-individuals
#6
Andrew S Huhn, Eric C Strain, George E Bigelow, Michael T Smith, Robert R Edwards, D Andrew Tompkins
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Managing acute pain in buprenorphine-maintained individuals in emergency or perioperative settings is a significant challenge. This study compared analgesic and abuse liability effects of adjunct hydromorphone and buprenorphine using quantitative sensory testing, a model of acute clinical pain, in persons maintained on 12 to 16 mg sublingual buprenorphine/naloxone. METHODS: Participants (N = 13) were enrolled in a randomized within-subject, double-blind, placebo-controlled three-session experiment...
November 2, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30383544/mechanical-power-a-biomarker-for-the-lung
#7
Laurent Brochard, Andrew Bersten
No abstract text is available yet for this article.
October 31, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30383543/esophageal-pressure-monitoring-in-the-critically-ill-obese-subject
#8
Malcolm Lemyze, Aurélie Guiot, Maxime Granier
No abstract text is available yet for this article.
October 31, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30383542/blood-pressure-and-end-tidal-carbon-dioxide-ranges-during-aneurysm-occlusion-and-neurologic-outcome-after-an-aneurysmal-subarachnoid-hemorrhage
#9
Annemarie Akkermans, Judith A van Waes, Linda M Peelen, Gabriel J Rinkel, Wilton A van Klei
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Hypocapnia, hypotension, and hypertension during aneurysm occlusion in patients with an aneurysmal subarachnoid hemorrhage may lead to a poor prognosis, but evidence for end-tidal carbon dioxide (ETCO2) and mean arterial pressure (MAP) targets is lacking. Within the ranges of standardized treatment, the authors aimed to study the association between hypocapnia (PaCO2 < 35 mmHg), hypotension (MAP < 80 mmHg), and hypertension (MAP >100 mmHg) during general anesthesia for aneurysm occlusion and neurologic outcome...
October 31, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30379649/defining-an-intraoperative-hypotension-threshold-in-association-with-stroke-in-cardiac-surgery-erratum
#10
(no author information available yet)
No abstract text is available yet for this article.
October 30, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30376457/total-intravenous-anesthesia-versus-inhalation-anesthesia-for-breast-cancer-surgery-a-retrospective-cohort-study
#11
Seokha Yoo, Han-Byoel Lee, Wonshik Han, Dong-Young Noh, Sun-Kyung Park, Won Ho Kim, Jin-Tae Kim
WHAT WE KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: The association between type of anesthesia used and recurrence of cancer remains controversial. This retrospective cohort study compared the influence of total IV anesthesia and inhalation anesthesia on the primary outcome of recurrence-free survival after breast cancer surgery. METHODS: The authors reviewed the electronic medical records of patients who had breast cancer surgery at a tertiary care teaching hospital between January 2005 and December 2013...
October 29, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30362992/madelung-s-disease-and-airway-management
#12
Ángel Becerra-Bolaños, Lucía Valencia, Leonardo Cabrera-Ramírez, Aurelio Rodríguez-Pérez
No abstract text is available yet for this article.
October 17, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30362991/aging-and-relevance-in-academic-medicine
#13
Thomas J Papadimos
No abstract text is available yet for this article.
October 17, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30335626/cognitive-effects-of-perioperative-pregabalin-secondary-exploratory-analysis-of-a-randomized-placebo-controlled-study
#14
Marianne Myhre, Henrik Børsting Jacobsen, Stein Andersson, Audun Stubhaug
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Pregabalin has shown opioid sparing and analgesic effects in the early postoperative period; however, perioperative effects on cognition have not been studied. A randomized, parallel group, placebo-controlled investigation in 80 donor nephrectomy patients was previously performed that evaluated the analgesic, opioid-sparing, and antihyperalgesic effects of pregabalin. This article describes a secondary exploratory analysis that tested the hypothesis that pregabalin would impair cognitive function compared to placebo...
October 17, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30335625/norepinephrine-infusion-for-preventing-postspinal-anesthesia-hypotension-during-cesarean-delivery-a-randomized-dose-finding-trial
#15
Ahmed M Hasanin, Sarah M Amin, Nora A Agiza, Mohamed K Elsayed, Sherin Refaat, Hazem A Hussein, Tamer I Rouk, Mostafa Alrahmany, Mohamed E Elsayad, Khaled A Elshafaei, Amira Refaie
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Norepinephrine has been recently introduced for prophylaxis against postspinal hypotension during cesarean delivery; however, no data are available regarding its optimum dose. The objective of this study is to compare three infusion rates of norepinephrine for prophylaxis against postspinal hypotension during cesarean delivery. METHODS: The authors conducted a double-blinded, randomized, controlled study including full-term pregnant women scheduled for cesarean delivery...
October 17, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30325744/activation-of-parabrachial-nucleus-glutamatergic-neurons-accelerates-reanimation-from-sevoflurane-anesthesia-in-mice
#16
Tian-Xiao Wang, Bo Xiong, Wei Xu, Hao-Hua Wei, Wei-Min Qu, Zong-Yuan Hong, Zhi-Li Huang
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: The parabrachial nucleus (PBN), which is a brainstem region containing glutamatergic neurons, is a key arousal nucleus. Injuries to the area often prevent patient reanimation. Some studies suggest that brain regions that control arousal and reanimation are a key part of the anesthesia recovery. Therefore, we hypothesize that the PBN may be involved in regulating emergence from anesthesia. METHODS: We investigated the effects of specific activation or inhibition of PBN glutamatergic neurons on sevoflurane general anesthesia using the chemogenetic "designer receptors exclusively activated by designer drugs" approach...
October 16, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30312182/triple-low-alerts-do-not-reduce-mortality-a-real-time-randomized-trial
#17
Daniel I Sessler, Alparslan Turan, Wolf H Stapelfeldt, Edward J Mascha, Dongsheng Yang, Ehab Farag, Jacek Cywinski, Claudene Vlah, Tatyana Kopyeva, Allen L Keebler, Mauricio Perilla, Mangakalaraip Ramachandran, Sean Drahuschak, Kristina Kaple, Andrea Kurz
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Triple-low events (mean arterial pressure less than 75 mmHg, Bispectral Index less than 45, and minimum alveolar fraction less than 0.8) are associated with mortality but may not be causal. This study tested the hypothesis that providing triple-low alerts to clinicians reduces 90-day mortality. METHODS: Adults having noncardiac surgery with volatile anesthesia and Bispectral Index monitoring were electronically screened for triple-low events...
October 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30277932/positive-end-expiratory-pressure-and-mechanical-power
#18
Francesca Collino, Francesca Rapetti, Francesco Vasques, Giorgia Maiolo, Tommaso Tonetti, Federica Romitti, Julia Niewenhuys, Tim Behnemann, Luigi Camporota, Günter Hahn, Verena Reupke, Karin Holke, Peter Herrmann, Eleonora Duscio, Francesco Cipulli, Onnen Moerer, John J Marini, Michael Quintel, Luciano Gattinoni
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Positive end-expiratory pressure is usually considered protective against ventilation-induced lung injury by reducing atelectrauma and improving lung homogeneity. However, positive end-expiratory pressure, together with tidal volume, gas flow, and respiratory rate, contributes to the mechanical power required to ventilate the lung. This study aimed at investigating the effects of increasing mechanical power by selectively modifying its positive end-expiratory pressure component...
October 2, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30277930/identifying-and-treating-opioid-side-effects-the-development-of-methylnaltrexone
#19
Jonathan Moss
Methylnaltrexone Reverses Chronic Opioid-induced Constipation: A Randomized, Controlled Trial. By Yuan CS, Foss JF, O'Connor M, Osinski J, Karrison T, Moss J, Roizen MF. JAMA 2000; 283:367-72. Reprinted with permission. CONTEXT: Constipation is the most common chronic adverse effect of opioid pain medications in patients who require long-term opioid administration, such as patients with advanced cancer, but conventional measures for ameliorating constipation often are insufficient. OBJECTIVE: To evaluate the efficacy of methylnaltrexone, the first peripheral opioid receptor antagonist, in treating chronic methadone-induced constipation...
October 2, 2018: Anesthesiology
https://www.readbyqxmd.com/read/30260896/sphygmomanometer-for-invasive-blood-pressure-monitoring-in-a-medical-mission
#20
Kun-Ming Tao, Sann Sokha, Hong-Bin Yuan
No abstract text is available yet for this article.
September 26, 2018: Anesthesiology
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