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European Heart Journal

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https://www.readbyqxmd.com/read/28087606/reinnervation-post-heart-transplantation
#1
Avishay Grupper, Henry Gewirtz, Sudhir Kushwaha
Heart transplantation results in complete denervation of the donor heart with loss of afferent and efferent nerve connections. The majority of patients remain completely denervated during the first 6-12 months following transplantation. Evidence of reinnervation is usually found during the second year after transplantation and involve the myocardial muscle, sinoatrial node, and coronary vessels, but remains incomplete and regionally limited many years post-transplant. Restoration of cardiac innervation can improve exercise capacity as well as blood flow regulation in the coronary arteries, and hence improve quality of life...
January 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28087605/histopathological-workup-of-a-hybrid-implanted-melody%C3%A2-valve-in-mitral-valve-position
#2
Martin Schmiady, Oliver Kretschmar, Michael Hübler, Matthias Sigler
No abstract text is available yet for this article.
January 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28087604/hiv-infection-acs-pci-and-high-platelet-reactivity-ingredients-for-a-perfect-thrombotic-storm
#3
EDITORIAL
Paul A Gurbel, Christopher R deFilippi, Kevin P Bliden, Udaya S Tantry
No abstract text is available yet for this article.
January 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28087603/coronary-microvascular-reserve-and-outcome-in-aortic-stenosis-pathophysiological-significance-vs-clinical-relevance
#4
EDITORIAL
Patrizio Lancellotti, Alain Nchimi
No abstract text is available yet for this article.
January 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28082329/tortuous-great-artery-in-association-with-partial-anomalous-pulmonary-venous-connection-in-an-infant
#5
Jianhua Li, Yunfei Ling, Sandeep Bhushan, Qi An
No abstract text is available yet for this article.
January 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28082330/defining-the-genetic-architecture-of-hypertrophic-cardiomyopathy-re-evaluating-the-role-of-non-sarcomeric-genes
#6
Roddy Walsh, Rachel Buchan, Alicja Wilk, Shibu John, Leanne E Felkin, Kate L Thomson, Tang Hak Chiaw, Calvin Chin Woon Loong, Chee Jian Pua, Claire Raphael, Sanjay Prasad, Paul J Barton, Birgit Funke, Hugh Watkins, James S Ware, Stuart A Cook
AIM: Hypertrophic cardiomyopathy (HCM) exhibits genetic heterogeneity that is dominated by variation in eight sarcomeric genes. Genetic variation in a large number of non-sarcomeric genes has also been implicated in HCM but not formally assessed. Here we used very large case and control cohorts to determine the extent to which variation in non-sarcomeric genes contributes to HCM. METHODS AND RESULTS: We sequenced known and putative HCM genes in a new large prospective HCM cohort (n = 804) and analysed data alongside the largest published series of clinically genotyped HCM patients (n = 6179), previously published HCM cohorts and reference population samples from the exome aggregation consortium (ExAC, n = 60 706) to assess variation in 31 genes implicated in HCM...
January 11, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28077467/gut-microbiota-dependent-trimethylamine-n-oxide-in-acute-coronary-syndromes-a-prognostic-marker-for-incident-cardiovascular-events-beyond-traditional-risk-factors
#7
Xinmin S Li, Slayman Obeid, Roland Klingenberg, Baris Gencer, François Mach, Lorenz Räber, Stephan Windecker, Nicolas Rodondi, David Nanchen, Olivier Muller, Melroy X Miranda, Christian M Matter, Yuping Wu, Lin Li, Zeneng Wang, Hassan S Alamri, Valentin Gogonea, Yoon-Mi Chung, W H Wilson Tang, Stanley L Hazen, Thomas F Lüscher
AIMS: Systemic levels of trimethylamine N-oxide (TMAO), a pro-atherogenic and pro-thrombotic metabolite produced from gut microbiota metabolism of dietary trimethylamine (TMA)-containing nutrients such as choline or carnitine, predict incident cardiovascular event risks in stable primary and secondary prevention subjects. However, the prognostic value of TMAO in the setting of acute coronary syndromes (ACS) remains unknown. METHODS AND RESULTS: We investigated the relationship of TMAO levels with incident cardiovascular risks among sequential patients presenting with ACS in two independent cohorts...
January 11, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28077471/individual-risk-stratification-in-adult-congenital-heart-disease-the-way-to-go
#8
EDITORIAL
Werner Budts
No abstract text is available yet for this article.
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28077470/comprehensive-efforts-to-increase-adherence-to-statin-therapy
#9
REVIEW
Alexander Vonbank, Stefan Agewall, Keld Per Kjeldsen, Basil S Lewis, Christian Torp-Pedersen, Claudio Ceconi, Christian Funck-Brentano, Juan Carlos Kaski, Alexander Niessner, Juan Tamargo, Thomas Walther, Sven Wassmann, Giuseppe Rosano, Harald Schmidt, Christoph H Saely, Heinz Drexel
No abstract text is available yet for this article.
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28077469/risk-factors-for-excess-mortality-in-adults-with-congenital-heart-diseases
#10
Jose Maria Oliver, Pastora Gallego, Ana Elvira Gonzalez, Diego Garcia-Hamilton, Pablo Avila, Raquel Yotti, Ignacio Ferreira, Francisco Fernandez-Aviles
AIMS: To examine factors related to excess mortality in a cohort of adults with congenital heart disease (CHD). METHODS AND RESULTS: We conducted a survival analysis using prospective data of 3311 adults with CHD [50.5% males, median age at entry 22.5 years (IQR 18-39), median follow-up time 10.5 years (IQR: 4.4-18)]. Survival status of each patient was further verified by cross checking with the Spanish National Death Index. During a total follow-up of 37608 person-years, 336 (10%) patients died...
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28077468/integrated-imaging-of-echocardiography-and-computed-tomography-to-grade-mitral-regurgitation-severity-in-patients-undergoing-transcatheter-aortic-valve-implantation
#11
Philippe J van Rosendael, Suzanne E van Wijngaarden, Vasileios Kamperidis, William K F Kong, Melissa Leung, Nina Ajmone Marsan, Victoria Delgado, Jeroen J Bax
AIMS: Quantitative mitral regurgitation (MR) grading remains challenging. This study evaluated the concept of integrating echocardiography and computed tomography for grading MR severity. Specifically, an integrated parameter was developed that combines the true cross-sectional mitral regurgitant orifice area (ROA) assessed with multi-detector row computed tomography (MDCT) with flow data from echocardiography. METHODS AND RESULTS: Systolic MDCT data of 73 patients, referred for transcatheter aortic valve implantation (TAVI) who also had MR, were evaluated...
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28073865/angiogenic-gene-therapy-in-cardiovascular-diseases-dream-or-vision
#12
REVIEW
Seppo Ylä-Herttuala, Charles Bridges, Michael G Katz, Petra Korpisalo
Chronic cardiovascular diseases are significant health problems. Although current treatment strategies have tremendously improved disease management, up to 30% of these patients cannot be successfully treated with current treatment approaches and new treatment strategies are clearly needed. Gene therapy and therapeutic vascular growth may provide a new treatment option for these patients. Several growth factors, like vascular endothelial growth factors, fibroblast growth factors and hepatocyte growth factor have been tested in clinical trials...
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28073864/mitraclip-improves-mitral-valve-geometry-in-complex-organic-mitral-regurgitation-insights-from-three-dimensional-echocardiography
#13
Philippe Debonnaire, Frank van der Kley, Nina Ajmone Marsan, Victoria Delgado
No abstract text is available yet for this article.
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28073863/revisiting-sex-differences-in-outcomes-in-non-valvular-atrial-fibrillation-a-population-based-cohort-study
#14
Christel Renoux, Janie Coulombe, Samy Suissa
AIMS: In patients with non-valvular atrial fibrillation (NVAF), it is uncertain whether the higher risk of ischaemic stroke in women reported in some studies is due to residual confounding. We assessed this association using standard time-fixed and more accurate time-dependent adjustment for confounders. METHODS AND RESULTS: Using the computerized databases of the Régie de l'assurance maladie du Québec (RAMQ), we identified a cohort of patients with NVAF during 2000-2009 and RAMQ medication coverage...
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28073862/transcatheter-tricuspid-valve-repair-toward-a-surgical-standard-first-in-man-report-of-direct-annuloplasty-with-a-cardioband-device-to-treat-severe-functional-tricuspid-regurgitation
#15
Shingo Kuwata, Maurizio Taramasso, Fabian Nietlispach, Francesco Maisano
No abstract text is available yet for this article.
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28073861/the-quest-for-a-successful-cell-based-therapeutic-approach-for-heart-failure
#16
EDITORIAL
Ana Marie Landin, Joshua M Hare
No abstract text is available yet for this article.
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28073860/cardiac-dysfunction-and-cognitive-decline
#17
EDITORIAL
Jack C de la Torre
No abstract text is available yet for this article.
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28069736/too-weak-to-withstand-the-strain-another-piece-in-the-crt-puzzle
#18
EDITORIAL
Jedrzej Kosiuk, Emmanuel Koutalas, Ole-A Breithardt
No abstract text is available yet for this article.
January 9, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28069735/life-threatening-acute-occlusion-between-interposed-graft-and-left-coronary-artery-after-modified-bentall-operation
#19
Daigo Hiraya, Tomoya Hoshi, Kazutaka Aonuma, Akira Sato
No abstract text is available yet for this article.
January 9, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28069734/life-threatening-simultaneous-acute-stent-thrombosis-associated-with-anaphylactic-shock-due-to-contrast-material
#20
Akira Sato, Daiki Akiyama, Tomoya Hoshi, Kazutaka Aonuma
No abstract text is available yet for this article.
January 9, 2017: European Heart Journal
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