We have located links that may give you full text access.
Preemptive aortic side branch embolization during EVAR using the Excluder stent-graft system: A prospective multicenter study.
Journal of Vascular and Interventional Radiology : JVIR 2024 March 12
PURPOSE: The occurrence of endoleaks, particularly type 2 endoleaks (EL2), is the primary cause of poor long-term prognosis after endovascular aneurysm repair (EVAR). This study aimed to evaluate the efficacy and safety of preemptive transcatheter arterial embolization (P-TAE) for aortic side branches (ASBs) to prevent EL2 before EVAR using the Excluder stent-graft system (EXCLUDER).
MATERIALS AND METHODS: In this prospective, multicenter study, 80 patients (mean age, 79.1±6.7 years; 85.0% male patients; mean aneurysmal sac diameter, 48.4±7.4 mm) meeting the eligibility criteria were prospectively enrolled from nine hospitals. Before EVAR, p-TAE was performed to embolize the patent ASBs originating from the abdominal aortic aneurysm. Contrast-enhanced computed tomography was performed at 1 month and 6 months after EVAR. The primary endpoint was EL2 incidence at 6 months, and the secondary endpoints were aneurysmal sac diameter changes at 6 and 12 months, P-TAE outcomes, complications related to P-TAE, re-intervention, and aneurysm-related mortality.
RESULTS: All patients successfully underwent P-TAE without serious complications. Coil embolization was successful in 81.6% of ASBs. EL2 incidence at 6 months was identified in 18/70 (25.7%) patients. Aneurysmal sac diameter shrinkage (≥5 mm) was observed in 30.0% of patients at 6 months and in 40.9% at 12 months. Only one patient required re-intervention for EL2 within 1 year of EVAR; aneurysm-related deaths were not observed.
CONCLUSION: P-TAE for ASBs before EVAR using EXCLUDER is a safe and effective strategy. It aids in achieving early aneurysmal sac shrinkage and reduces EL2 re-intervention at 1 year after EVAR.
MATERIALS AND METHODS: In this prospective, multicenter study, 80 patients (mean age, 79.1±6.7 years; 85.0% male patients; mean aneurysmal sac diameter, 48.4±7.4 mm) meeting the eligibility criteria were prospectively enrolled from nine hospitals. Before EVAR, p-TAE was performed to embolize the patent ASBs originating from the abdominal aortic aneurysm. Contrast-enhanced computed tomography was performed at 1 month and 6 months after EVAR. The primary endpoint was EL2 incidence at 6 months, and the secondary endpoints were aneurysmal sac diameter changes at 6 and 12 months, P-TAE outcomes, complications related to P-TAE, re-intervention, and aneurysm-related mortality.
RESULTS: All patients successfully underwent P-TAE without serious complications. Coil embolization was successful in 81.6% of ASBs. EL2 incidence at 6 months was identified in 18/70 (25.7%) patients. Aneurysmal sac diameter shrinkage (≥5 mm) was observed in 30.0% of patients at 6 months and in 40.9% at 12 months. Only one patient required re-intervention for EL2 within 1 year of EVAR; aneurysm-related deaths were not observed.
CONCLUSION: P-TAE for ASBs before EVAR using EXCLUDER is a safe and effective strategy. It aids in achieving early aneurysmal sac shrinkage and reduces EL2 re-intervention at 1 year after EVAR.
Full text links
Related Resources
Trending Papers
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Prevention and treatment of ischaemic and haemorrhagic stroke in people with diabetes mellitus: a focus on glucose control and comorbidities.Diabetologia 2024 April 17
British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease.Rheumatology 2024 April 17
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Albumin: a comprehensive review and practical guideline for clinical use.European Journal of Clinical Pharmacology 2024 April 13
Eosinophilic Esophagitis: Clinical Pearls for Primary Care Providers and Gastroenterologists.Mayo Clinic Proceedings 2024 April
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app