We have located links that may give you full text access.
Preventing sarcopenic obesity among breast cancer patients who receive adjuvant chemotherapy: results of a feasibility study.
Clinical Exercise Physiology 2002 Februrary
PURPOSE: Weight gain is a common side effect of adjuvant chemotherapy for breast cancer - a side effect that decreases quality of life and also may decrease both disease-free and overall survival. This weight gain also is unique, since patients lose lean body mass while they gain weight. These body composition changes become apparent within six months of diagnosis. METHODS: We explored whether a clinic-based exercise program, which promoted a specialized program of strength training, aerobic activity and a healthful (</=20% fat; fruit, vegetable and calcium-rich) diet could prevent body composition change among Stage I/II premenopausal breast cancer patients who would receive adjuvant chemotherapy. Dual energy x-ray absorptiometry was used to assess body composition at both baseline and at six-month follow-up. Data from patients participating in the intervention (N=9) were compared to data from historic patient controls (N=36). RESULTS: Mean changes (SE) in body weight and composition at 6 month follow-up were as follows among historic patient controls and intervention participants, respectively: body weight +2.2(.4) kg vs. -2.0(1.3) kg (p=.02); % body fat +1.8(1.6)% vs. -1.3(1.2)% (p=.002); lean body mass -0.3(.01) kg vs. +0.1(1.5) kg (p=.80); and fat mass +2.0(.3) kg vs. -1.2(1.5) kg (p=.04). CONCLUSION: Data from this pilot study suggest that exercise/diet interventions may yield promise in preventing adverse chemotherapy-induced weight and body composition changes among young women who receive adjuvant chemotherapy for breast cancer, and that further study is needed. Since over half of the women approached for this intervention study refused on the basis of time and travel requirements, interventions that utilize home-based approaches may be necessary to reach greater numbers and a greater diversity of patients.
Full text links
Related Resources
Trending Papers
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Prevention and treatment of ischaemic and haemorrhagic stroke in people with diabetes mellitus: a focus on glucose control and comorbidities.Diabetologia 2024 April 17
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Eosinophilic Esophagitis: Clinical Pearls for Primary Care Providers and Gastroenterologists.Mayo Clinic Proceedings 2024 April
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app