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Changes in Weight or Body Composition by Frailty Status: A Pilot Study.
Journal of Nutrition in Gerontology and Geriatrics 2024 March 13
Weight loss may benefit older adults with obesity. However, it is unknown whether individuals with different frailty phenotypes have different outcomes following weight loss. Community-dwelling adults aged ≥65 ( n = 53) with a body mass index ≥30 kg/m2 were recruited for a six-month, single-arm, technology-based weight loss study. A 45-item frailty index identified frailty status using subjective and objective measures from a baseline geriatric assessment. At baseline, n = 22 participants were classified as pre-frail (41.5%) and n = 31 were frail (58.5%), with no differences in demographic characteristics. While weight decreased significantly in both groups (pre-frail: 90.8 ± 2.7 kg to 85.5 ± 2.4 kg ( p < 0.001); frail: 102.7 ± 3.4 kg to 98.5 ± 3.3 kg ( p < 0.001), no differences were observed between groups for changes in weight ( p = 0.30), appendicular lean mass/height2 ( p = 0.47), or fat-free mass ( p = 0.06). Older adults with obesity can safely lose weight irrespective of frailty status using a technology-based approach. Further investigation is needed to determine whether the impact of specific lifestyle interventions differ by frailty status.
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