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Growing Awareness: Limited Testing and Screening Bias for Hepatitis Delta Virus in Utah 2000-2021.
Journal of Infectious Diseases 2024 March 9
BACKGROUND: This study assessed the epidemiology of hepatitis delta virus (HDV) within the University of Utah UHealth health care system (2000-2021).
METHODS: Analysis of HDV/HBV testing, diagnostic codes, liver enzymes, and comorbidities was performed.
RESULTS: Among the 1962 HBV patients, only 22.2% underwent HDV testing, revealing an 8.3% positivity rate for HDV coinfections. This study observed a consistent increase in HBV and HDV cases, with higher HDV detection rates linked to increased testing. Limited HDV testing and potential screening biases were evident.
DISCUSSION: Improved HDV testing and surveillance are crucial for early detection and implementation of targeted therapies.
METHODS: Analysis of HDV/HBV testing, diagnostic codes, liver enzymes, and comorbidities was performed.
RESULTS: Among the 1962 HBV patients, only 22.2% underwent HDV testing, revealing an 8.3% positivity rate for HDV coinfections. This study observed a consistent increase in HBV and HDV cases, with higher HDV detection rates linked to increased testing. Limited HDV testing and potential screening biases were evident.
DISCUSSION: Improved HDV testing and surveillance are crucial for early detection and implementation of targeted therapies.
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