We have located links that may give you full text access.
Endovascular therapy for acute vertebrobasilar occlusion underlying atherosclerosis: A single institution experience.
Clinical Neurology and Neurosurgery 2019 January
OBJECTIVE: To compare the safety and efficacy of endovascular therapy in acute ischemic stroke (AIS) caused by large artery occlusion (LAO) in the posterior circulation with or without intracranial atherosclerosis (ICAS).
PATIENT AND METHODS: The study enrolled patients who underwent endovascular therapy for AIS caused by posterior circulation LAO. Inclusion criteria for endovascular therapy of vertebrobasilar occlusion were as follows: (1) CTA or MRA confirmed acute vertebrobasilar occlusion; (2) baseline NIHSS score ≥2; (3) premorbid mRS score ≤2; (4) onset or last known well time to puncture within 24 h; (5) pc-ASPECTS ≥6. Outcomes were compared between the ICAS group and the non-ICAS group.
RESULTS: A total of 67 patients were recruited in this study, of which 35 (52.2%) had underlying ICAS, while 32 (47.8%) did not. Rescue therapies were more commonly performed in the ICAS group (82.9% vs. 34.4%; p = 0.000). The proportion of favorable outcome at 90 days was higher in the ICAS group than in the non-ICAS group (71.4% vs. 46.9%; p = 0.041). There was no significant difference in symptomatic ICH (2.9% vs. 6.3%, p = 0.603) or death within 90 days (22.9% vs. 37.5%, p = 0.191) between the two groups. The baseline GCS score (OR 1.281, 95% CI: 1.085-1.513; p = 0.004) and PMI (OR 0.402, 95% CI: 0.233 to 0.693; p = 0.001) were independently associated with favorable outcome at 90 days.
CONCLUSIONS: Endovascular therapy with stent-retriever thrombectomy followed by rescue treatment can achieve high rates of successful revascularization and favorable outcome in the treatment of AIS caused by posterior circulation LAO.
PATIENT AND METHODS: The study enrolled patients who underwent endovascular therapy for AIS caused by posterior circulation LAO. Inclusion criteria for endovascular therapy of vertebrobasilar occlusion were as follows: (1) CTA or MRA confirmed acute vertebrobasilar occlusion; (2) baseline NIHSS score ≥2; (3) premorbid mRS score ≤2; (4) onset or last known well time to puncture within 24 h; (5) pc-ASPECTS ≥6. Outcomes were compared between the ICAS group and the non-ICAS group.
RESULTS: A total of 67 patients were recruited in this study, of which 35 (52.2%) had underlying ICAS, while 32 (47.8%) did not. Rescue therapies were more commonly performed in the ICAS group (82.9% vs. 34.4%; p = 0.000). The proportion of favorable outcome at 90 days was higher in the ICAS group than in the non-ICAS group (71.4% vs. 46.9%; p = 0.041). There was no significant difference in symptomatic ICH (2.9% vs. 6.3%, p = 0.603) or death within 90 days (22.9% vs. 37.5%, p = 0.191) between the two groups. The baseline GCS score (OR 1.281, 95% CI: 1.085-1.513; p = 0.004) and PMI (OR 0.402, 95% CI: 0.233 to 0.693; p = 0.001) were independently associated with favorable outcome at 90 days.
CONCLUSIONS: Endovascular therapy with stent-retriever thrombectomy followed by rescue treatment can achieve high rates of successful revascularization and favorable outcome in the treatment of AIS caused by posterior circulation LAO.
Full text links
Related Resources
Trending Papers
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows.Endocrine Reviews 2024 April 28
The Tricuspid Valve: A Review of Pathology, Imaging, and Current Treatment Options: A Scientific Statement From the American Heart Association.Circulation 2024 April 26
Intravenous infusion of dexmedetomidine during the surgery to prevent postoperative delirium and postoperative cognitive dysfunction undergoing non-cardiac surgery: a meta-analysis of randomized controlled trials.European Journal of Medical Research 2024 April 19
Interstitial Lung Disease: A Review.JAMA 2024 April 23
Management of Diverticulitis: A Review.JAMA Surgery 2024 April 18
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app