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Clinical Neurology and Neurosurgery

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https://www.readbyqxmd.com/read/28092730/serum-agr2-as-a-useful-biomarker-for-pituitary-adenomas
#1
Mamatemin Tohti, Junyang Li, Chao Tang, Guodao Wen, Abdukeyum Abdujilil, Parhat Yizim, Chiyuan Ma
OBJECTIVE: This study aims to evaluate whether the serum Anterior Gradient-2 (AGR2) can be used as a potential biomarker screening in the diagnosis of Pituitary adenomas(PAs). PATIENTS AND METHODS: The serum AGR2 protein levels were preoperatively measured in 163 PA patients, 43 patients with other sellar lesions excluding PAs, 7 patients with prostate cancer as a positive control and 20 normal people(10 female and 10 male) using Enzyme-Linked ImmunoSorbent Assay (ELISA)...
January 9, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28086154/full-endoscopic-versus-micro-endoscopic-and-open-discectomy-a-systematic-review-and-meta-analysis-of-outcomes-and-complications
#2
Kevin Phan, Joshua Xu, Konrad Schultz, Mohammed Ali Alvi, Victor M Lu, Panagiotis Kerezoudis, Patrick R Maloney, Meghan E Murphy, Ralph J Mobbs, Mohamad Bydon
OBJECTIVES: The purpose of this study was to systematically compare the effectiveness and safety of full-endoscopic discectomy (FED) and micro-endoscopic discectomy (MED) with open discectomy (OD) for the treatment of symptomatic lumbar disc herniation. METHODS: Electronic searches were performed using six databases from their inception to February 2016, identifying all relevant randomized controlled trials and comparative observational studies comparing either FED or MED with OD...
January 8, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28076822/an-in-vitro-analysis-of-the-size-and-shape-of-cryolesions-for-facet-joint-denervation
#3
T Wolter, Y Bozhkov, S M Knoeller
OBJECTIVES: Lumbar facet joint syndrome (LFJS) is the cause of lower back pain in 15-54% of the patients. Clinical studies of cryotherapy for LFJS have reported promising outcomes. However, few studies have focused on the technical aspects of cryoneurolysis for LFJS. The aim of the study was to determine the size and shape of cryolesions in vitro and to determine how they are affected by the duration of freezing, size of the cryoprobe and distance and angulation to an osseous boundary layer...
January 4, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28068526/herniated-gyrus-rectus-causing-idiopathic-compression-of-the-optic-chiasm
#4
Jacob Smith, Megan M Jack, Jeremy C Peterson, Roukoz B Chamoun
Anomalies in the frontal lobe can interfere with visual function by compression of the optic chiasm and nerve. The gyrus rectus is located at the anterior cranial fossa floor superior to the intracranial optic nerves and chiasm. Compression of these structures by the gyrus rectus is often caused by neoplastic or dysplastic growth in the area. We report a rare case of a herniated gyrus rectus impinged on the optic chiasm and nerve without a clear pathological cause for the herniation.
January 3, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28088560/role-of-comorbidities-and-in-hospital-complications-in-short-term-status-epilepticus-outcome
#5
Marco Belluzzo, Giovanni Furlanis, Lara Stragapede, Fabrizio Monti
OBJECTIVE: pre-morbid patient conditions and hospitalization complications possibly play a role in status epilepticus short-term outcome, although evidence is incomplete and non-conclusive. The study's aim was to define whether comorbidities and in-hospital complications arising after status epilepticus affect its prognosis. METHODS: A retrospective single center study was carried out. All selected patients were adults presenting an EEG-proven status epilepticus episode between 2003 and 2014...
December 30, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28081463/analysis-of-the-results-of-recurrent-intracranial-meningiomas-treated-with-re-radiosurgery
#6
Moinay Kim, Do Hee Lee, Hyun Jung Kim Rn, Young Hyun Cho, Jeong Hoon Kim, Do Hoon Kwon
OBJECTS: Meningioma is the most common intracranial neoplasm, comprising approximately 30% of all primary intracranial tumors (Claus et al., 2005) [1]. Treatment options include observation, microsurgical resection, stereotactic radiosurgery (SRS), and whole brain radiation therapy (WBRT). Gamma knife radiosurgery (GKRS) is a very effective treatment for intracranial meningiomas; previous studies showed the tumor control rate at 5-10 years of follow-up as 84.3%-100% in all cases (Feigl et al...
December 29, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28073036/does-preoperative-oral-carbohydrate-treatment-reduce-the-postoperative-surgical-stress-response-in-lumbar-disc-surgery
#7
Ozlem Korkmaz Dilmen, Ercument Yentur, Yusuf Tunali, Huriye Balci, Mois Bahar
OBJECTIVES: Surgical trauma produces metabolic and hormonal responses, which are characterized by insulin resistance. Due to extension of the preoperative fasting period, which increases the magnitude of postoperative insulin resistance, preoperative oral carbohydrates (POC) have been developed. PATIENTS AND METHODS: This prospective, randomized, controlled study was performed on 43 ASA I-II patients undergoing elective microsurgical lumbar discectomy. The intervention group received oral carbohydrate solution 800mL the night before and 400mL 2h prior to operation...
December 29, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28061362/developing-easy-to-perform-routine-mri-measurements-as-potential-surrogates-for-cognitive-impairment-in-ms
#8
Sarah A Morrow, Suresh Menon, Heather Rosehart, Manas Sharma
OBJECTIVES: One of the most frequently disabling symptoms in Multiple Sclerosis (MS) is cognitive impairment which is often insidious in onset and therefore difficult to recognize in the early stages, for both persons with MS and clinicians. A biomarker that would help identify those at risk of cognitive impairment, or with only mild impairment, would be a useful tool for clinicians. Using MRI, already an integral tool in the diagnosis and monitoring of disease activity in MS, would be ideal...
December 29, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28056436/one-stage-posterior-surgical-management-of-lumbosacral-spinal-tuberculosis-with-nonstructural-autograft
#9
Jia-Ming Liu, Yang Zhou, Ai-Fen Peng, Xuan-Yin Chen, Wen-Zhao Chen, Xin-Hua Long, Shan-Hu Huang, Zhi-Li Liu
OBJECTIVE: Lumbosacral spinal tuberculosis is rare in current population. Previous studies have reported effective outcomes about anterior, antero-posterior and posterior surgery for treating tuberculosis of lumbosacral region. However, the bone grafts used in these studies are mainly structural bone and mesh cage. The purpose of this study is to evaluate the efficacy and safety of nonstructural autograft in the surgical treatment of lumbosacral tuberculosis by one-stage posterior procedure...
December 28, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28027505/impairment-of-dynamic-thiol-disulphide-homeostasis-in-patients-with-idiopathic-parkinson-s-disease-and-its-relationship-with-clinical-stage-of-disease
#10
Gonul Vural, Sadiye Gumusyayla, Hesna Bektas, Orhan Deniz, Murat Alisik, Ozcan Erel
OBJECTIVE: The aim of this study was to investigate dynamic thiol-disulphide homeostasis in patients with idiopathic Parkinson's disease and to determine its relationship with the clinical stage as assessed by the modified Hoehn and Yahr scale. DESIGN AND METHODS: Fifty-two patients with Parkinson's disease (PD), diagnosed according to the United Kingdom Brain Bank Criteria for idiopathic PD, and 41 healthy individuals were included in the study. Clinical staging of patients was performed according to the Hoehn and Yahr scale...
December 23, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28043024/utility-of-a-questionnaire-tool-quaras-for-localizing-and-lateralizing-seizures-in-the-epilepsy-monitoring-unit-emu
#11
Rima M Chaudhari, Bhargavi Ramanujam, Renjith Appukuttan, Anubha Sharma, Yuvraj Kunwar, Gaurav Tejaniya, Ajay Garg, Madakasira Vasantha Padma, Madhavi Tripathi, Chandrashekhar Bal, Deepa Dash, Sarat P Chandra, Manjari Tripathi
OBJECTIVES: An accurate description of the seizure semiology improves the recognition of the ictal onset zone and helps in hypothesizing the possible epileptogenic zone (EZ). Semiology based on a reliable description of seizures may be as good as investigative modalities, as has been shown by numerous studies. The main objective of this study was to apply a questionnaire-tool for auras and semiology (QUARAS) in refractory epilepsy cohort and compare its yield to that of standard history-taking...
December 22, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28027506/posterior-short-segment-fixation-in-thoracolumbar-unstable-burst-fractures-transpedicular-grafting-or-six-screw-construct
#12
Jen-Chung Liao, Kuo-Fon Fan
OBJECTIVES: Early implant failure and donor-site complication remain a concern in patients with thoracolumbar burst fracture underwent one-above and-below short-segment posterior pedicle screw fixation with fusion. Our aim was to evaluate the results of short-segment pedicle instrumentation enforced by two augmenting screws or injectable artificial bone cement in the fractured vertebra, and compare the differences between these two PATIENTS AND METHODS: We conducted a retrospective clinical and radiographic study...
December 21, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28012354/microsurgical-resection-of-juxtafacet-cysts-without-concomitant-fusion-long-term-follow-up-of-74-patients
#13
Christoph Scholz, Ulrich Hubbe, Evangelos Kogias, Roland Roelz, Jan-Helge Klingler
OBJECT: We report on our experience with treating juxtafacet cysts focusing on clinical outcome, rate of recurrence and secondary surgery, especially fusion. METHODS: This retrospective study evaluates patients who underwent surgical resection of juxtafacet cysts without concomitant fusion from 2002 to 2013 with a minimum follow-up of one year. RESULTS: Complete follow-up is available in 74 patients. Mean follow-up in all 74 patients was 69±34months (range, 14-140 months)...
December 16, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28013184/variables-determining-mortality-in-patients-with-acinetobacter-baumannii-meningitis-ventriculitis-treated-with-intrathecal-colistin
#14
Bahadır Ceylan, Ferhat Arslan, Oguz Resat Sipahi, Mustafa Sunbul, Bahar Ormen, İsmail N Hakyemez, Tuba Turunc, Yeşim Yıldız, Hasan Karsen, Gul Karagoz, Recep Tekin, Burcu Hizarci, Vedat Turhan, Sebnem Senol, Nefise Oztoprak, Mesut Yılmaz, Kevser Ozdemir, Sinan Mermer, Omer F Kokoglu, Ali Mert
AIM: To examine the variables associated with mortality in patients with Acinetobacter baumannii-related central nervous system infections treated with intrathecal colistin. MATERIALS AND METHODS: This multi-centre retrospective case control study included patients from 11 centres in Turkey, as well as cases found during a literature review. Only patients with CNS infections caused by multidrug-resistant or extensively drug-resistant Acinetobacter baumannii treated with intrathecal colistin were included in this study...
December 14, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27992822/thrombolytic-treatment-to-stroke-mimic-patients-via-telestroke
#15
Ganesh Asaithambi, Amy L Castle, Michael A Sperl, Jayashree Ravichandran, Aditi Gupta, Bridget M Ho, Sandra K Hanson
OBJECTIVE: The safety and outcomes of intravenous thrombolysis (IVT) to stroke patients via telestroke (TS) is similar to those presenting to stroke centers. Little is known on the accuracy of TS diagnosis among those receiving IVT. We sought to compare the rate of patients receiving IVT with diagnosis of ischemic stroke as opposed to stroke mimic (SM) in our TS network to those who presented to our comprehensive stroke center (CSC). MATERIALS AND METHODS: Consecutive patients receiving IVT between August 2014 and June 2015 were identified at our CSC and TS network...
December 14, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27987387/possible-common-neurological-breakdowns-for-alexithymia-and-humour-appreciation-deficit-a-case-study
#16
Panayiotis Patrikelis, George Konstantakopoulos, Giuliana Lucci, Vasileios K Katsaros, Damianos E Sakas, Stylianos Gatzonis, Giorgos Stranjalis
This brief work is an attempt to point to the possible common neurological breakdowns in giving rise to alexithymia, and impaired appreciation of humour. In particular, we present the case of a patient who lost the ability to enjoy humour after the surgical removal of a frontal groove meningioma, although he was still able to detect it, while at the same time was diagnosed with organic alexithymia. Our results indicate that problems in the affective appreciation of humour and in emotionalizing (alexithymic symptoms) may be the result of damage to the ventral-rostral portions of the ACG/mPFC, which prevent the patient from assessing the salience of emotion and motivational information, and generating emotional reactions; as a result he has trouble experiencing emotions, knowing how he and others feel, and enjoy humour...
December 12, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28006728/is-clipping-better-than-coiling-in-the-treatment-of-patients-with-oculomotor-nerve-palsies-induced-by-posterior-communicating-artery-aneurysms-a-systematic-review-and-meta-analysis
#17
REVIEW
Feng Zheng, Ying Dong, Peng Xia, Anastasios Mpotsaris, Pantelis Stavrinou, Gerrit Brinker, Roland Goldbrunner, Boris Krischek
OBJECTIVE: Posterior communicating artery aneurysms (PcomAAs) are the second most common aneurysm, accounting for 25% of all aneurysms and 50% of internal carotid artery aneurysms. It has been estimated that oculomotor nerve palsy (ONP) occurs in up to one-third of patients with posterior communicating artery (PcomA) aneurysms. Recent research showed a better outcome of ONP in patients with PcomAA after surgical clipping when compared to endovascular coiling. We compared the effect of clipping and coiling on recovery of ONP in the management of patients with PcomAAs...
December 11, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28012353/impact-of-timing-of-cranioplasty-on-hydrocephalus-after-decompressive-hemicraniectomy-in-malignant-middle-cerebral-artery-infarction
#18
Tobias Finger, Vincent Prinz, Evelyn Schreck, Alexandra Pinczolits, Simon Bayerl, Thomas Liman, Johannes Woitzik, Peter Vajkoczy
OBJECTIVE: Patients with malignant middle cerebral artery infarction frequently develop hydrocephalus after decompressive hemicraniectomy. Hydrocephalus itself and known shunt related complications after ventriculo-peritoneal shunt implantation may negatively impact patientś outcome. Here, we aimed to identify factors associated with the development of hydrocephalus after decompressive hemicraniectomy in malignant middle cerebral artery infarction. PATIENTS AND METHODS: A total of 99 consecutive patients with the diagnosis of large hemispheric infarctions and the indication for decompressive hemicraniectomy were included...
December 9, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27992823/the-effect-of-renal-dysfunction-on-short-term-outcomes-after-lumbar-fusion
#19
Taylor E Purvis, Remi A Kessler, Christine Boone, Benjamin D Elder, C Rory Goodwin, Daniel M Sciubba
OBJECTIVE: To compare post-lumbar decompression and fusion complication rates and mortality for patients without preoperative hemodialysis (HD) use with and without renal dysfunction as estimated by glomerular filtration rate (GFR) and creatinine levels. PATIENTS AND METHODS: Baseline and outcome data were obtained from the 2005-2014 American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database for patients over the age of 18 who underwent non-emergent lumbar fusion surgery...
December 6, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28012355/a-hero-in-the-strife
#20
EDITORIAL
Georges F Haddad, Patrick W Hitchon
No abstract text is available yet for this article.
December 5, 2016: Clinical Neurology and Neurosurgery
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