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Clinical Neurology and Neurosurgery

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https://www.readbyqxmd.com/read/28719872/health-related-quality-of-life-in-patients-undergoing-lumbar-total-disc-replacement-a-comparison-with-the-general-population
#1
Clavel Pablo, Gheorghe Ungureanu, Catalá Ignasi, Guillermo Montes, Xavier Málaga, Moisés Ríos
OBJECTIVES: In up to half of the cases, low back pain (LBP) is thought to be related to a degeneration of the lumbar disc. Lumbar total disc replacement (LTDR) emerged as an alternative to fusion, but its use and indications are still subject to debate. The purpose of this paper was to compare Health-related Quality of life (HRQOL) in patients undergoing LTDR for one or two-level degenerative disc disease (DDD) with the paired age and gender general population values and to assess functional disability and residual pain at one year after the surgical procedure...
July 11, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28719871/optic-neuritis-in-pregnancy-after-tdap-vaccination-report-of-two-cases
#2
Jose M Cabrera-Maqueda, Rocio Hernández-Clares, Ana E Baidez-Guerrero, Julian Ignacio Bermúdez Pío-Rendón, Jose J Martín Fernández
Two pregnant women developed one-eye blurring vision within three weeks after Tdap vaccination. Neurophtalmologic and MR examination confirmed an unilateral optic neuritis without evidence of underlying disease. Both patients had a full recovery, one after intravenous metilprednisolone. This is the first report of optic neuritis related with Tdap vaccination in pregnancy.
July 11, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28709008/iatrogenic-b12-deficient-peripheral-neuropathy-following-nitrous-oxide-administration-for-functional-tonic-leg-spasm-a-case-report
#3
Diego Kaski, Prateek Kumar, Elaine Murphy, Thomas T Warner
No abstract text is available yet for this article.
July 6, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28715708/the-evaluation-of-brain-perfusion-spect-using-an-easy-z-score-imaging-system-in-the-mild-cognitive-impairment-subjects-with-brain-amyloid-%C3%AE-deposition
#4
Makoto Takemaru, Noriyuki Kimura, Yoshitake Abe, Megumi Goto, Etsuro Matsubara
OBJECTIVE: The analysis of (99)mTc-ECD single-photon emission computed tomography (SPECT) images using the easy Z-score imaging system (eZIS) program is useful for the diagnosis of early AD in daily medical practice. However, it remains unclear whether eZIS analysis can identify the amnestic mild cognitive impairment (MCI) subjects with brain amyloid-β deposition. The aim of this study was to evaluate the usefulness of an eZIS analysis for predicting amnestic MCI subjects with brain amyloid β deposition...
July 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28709007/a-patient-with-childhood-onset-aggressive-parasomnia-diagnosed-50-years-later-with-idiopathic-rem-sleep-behavior-disorder-and-a-history-of-sleepwalking
#5
Junying Zhou, Bing Liang, Lina Du, Lu Tan, Xiangdong Tang
No abstract text is available yet for this article.
July 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28704779/circulating-mir-128-as-a-potential-diagnostic-biomarker-for-glioma
#6
REVIEW
Ruo-Fei Liang, Mao Li, Yuan Yang, Xiang Wang, Qing Mao, Yan-Hui Liu
OBJECTIVE: miR-128 in circulation is a promising marker for early diagnosis of glioma. A meta-analysis was performed to evaluate the diagnostic accuracy and clinical value of circulating miR-128 in patients with glioma. MATERIALS AND METHODS: A comprehensive literature search for relevant published articles (last search updated on December 29, 2016) was conducted in the Chinese Biomedical Literature Database, PubMed, and Embase. The quality assessment of diagnostic accuracy studies (QUADAS) tool was used to score the quality of the eligible studies...
July 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28704778/eradication-of-helicobacter-pylori-infection-might-improve-clinical-status-of-patients-with-parkinson-s-disease-especially-on-bradykinesia
#7
Huijing Liu, Wen Su, Shuhua Li, Wei Du, Xinxin Ma, Ying Jin, Kai Li, Haibo Chen
OBJECTIVES: Previous studies have shown that Helicobacter pylori infection might make clinical status worse in patients with Parkinson's disease and Helicobacter pylori eradication might improve clinical status by modifying the pharmacokinetics of L-dopa. Here, we investigate whether Helicobacter pylori eradication could benefit idiopathic parkinsonism and Helicobacter pylori infection will effect which aspect of motor symptom significantly. PATIENTS AND METHODS: A cohort study involving idiopathic Parkinson's disease patients, screened for Helicobacter status by (13)C urea breath test...
July 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28692908/surgical-outcomes-of-laminoplasty-for-cervical-spondylotic-myelopathy-in-very-elderly-patients-older-than-80-years-time-from-symptom-onset-to-surgery-and-changes-in-spinal-cord-signal-intensity-on-mri
#8
Naoki Notani, Masashi Miyazaki, Shozo Kanezaki, Toshinobu Ishihara, Hiroshi Tsumura
OBJECTIVE: We aimed to assess the surgical outcomes of laminoplasty for cervical spondylotic myelopathy (CSM) in very elderly patients (older than 80 years), focusing specifically on the time from symptom onset to surgery and on the loss in spinal cord signal intensity on magnetic resonance imaging (MRI). PATIENTS AND METHODS: We retrospectively reviewed 100 consecutive patients (61 males and 39 females) with CSM who underwent laminoplasty between 2006 and 2014...
July 1, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28704781/impacts-of-egfr-mutation-and-egfr-tkis-on-incidence-of-brain-metastases-in-advanced-non-squamous-nsclc
#9
Bao-Xiao Wang, Wei Ou, Xiao-Yong Mao, Zui Liu, Hui-Qi Wu, Si-Yu Wang
OBJECTIVE: Brain metastases remain lethal in lung cancer patients. The impacts of epidermal growth factor receptor (EGFR) mutations and EGFR tyrosine kinase inhibitors (TKIs) on the incidence of brain metastases in patients with advanced non-squamous non-small cell lung cancer (NSCLC) are still uncertain. PATIENTS AND METHODS: A total of 1672 patients with advanced non-squamous NSCLC with a definitive report on EGFR mutation status between January 2005 and June 2013 were retrospectively analyzed...
June 29, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28704780/acceleration-of-blood-flow-as-an-indicator-of-improved-hemodynamics-after-indirect-bypass-surgery-in-moyamoya-disease
#10
Sayaka Ogawa, Toshiyasu Ogata, Hirofumi Shimada, Hiroshi Abe, Toshiro Katsuta, Kenji Fukuda, Tooru Inoue
OBJECTIVE: The ultrasonography findings in the superficial temporal artery (STA) in Moyamoya disease patients treated with indirect bypass remain unclear. We evaluated the time-related changes in ultrasonography findings of the STA main trunk and branches in patients with Moyamoya disease who underwent encephalo-duro-arterio-synangiosis (EDAS). PATIENTS AND METHODS: Patients (n=21, 30 sides) with Moyamoya disease who underwent EDAS at Fukuoka University Hospital were prospectively registered between 2008 and 2015...
June 27, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28692909/pipeline-embolization-of-posterior-communicating-artery-aneurysms-associated-with-a-fetal-origin-posterior-cerebral-artery
#11
Adam N Wallace, Yasha Kayan, Matthew J Austin, Josser E Delgado Almandoz, Mudassar Kamran, DeWitte T Cross, Christopher J Moran, Joshua W Osbun, Akash P Kansagra
BACKGROUND AND PURPOSE: Flow diversion may have advantages in the treatment of posterior communicating artery (PComA) aneurysms associated with a fetal origin posterior cerebral artery (PCA), which can be challenging to treat with conventional techniques. However, a PComA incorporated into the aneurysm may prevent or delay aneurysm occlusion. Also, coverage of a fetal origin PCA risks infarction of a large vascular territory. The purpose of this study was to examine the safety and effectiveness of using the Pipeline Embolization Device (PED) to treat PComA aneurysms associated with a fetal origin PCA...
June 27, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28689103/-123-i-meta-iodobenzylguanidine-mibg-myocardial-scintigraphy-in-patients-showing-scans-without-evidence-of-dopaminergic-deficits-swedds
#12
Fumihito Yoshii, Yusuke Moriya, Tomohide Ohnuki, Masafuchi Ryo, Wakoh Takahashi, Saori Kohara, Jun Hashimoto
OBJECTIVE: Scans without evidence of dopaminergic deficits (SWEDDs) in dopamine transporter single-photon emission computed tomography (DAT-SPECT) are found in 3.6-19.6% of patients with clinically suspected Parkinson's disease (PD). We investigated whether combined use of (123)I-meta-iodobenzylguanidine (MIBG) myocardial scintigraphy would be helpful to differentiate PD among SWEDDs patients. PATIENTS AND METHODS: 145 patients with clinically suspected PD underwent both DAT-SPECT and MIBG myocardial scintigraphy...
June 27, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28689102/monthly-methylprednisolone-in-combination-with-interferon-beta-or-glatiramer-acetate-for-relapsing-remitting-multiple-sclerosis-a-multicentre-single-blind-prospective-trial
#13
Serkan Ozakbas, Bilge Piri Cinar, Gorkem Kosehasanoğullari, Turhan Kahraman, Didem Oz, Behice Bircan Kursun
OBJECTIVES: Multiple sclerosis is usually clinically characterized by repeated subacute relapses followed by remissions. Corticosteroids are used for relapses, and this treatment has been shown to increase the speed of recovery from these. We aimed to evaluate the efficacy and safety of pulsed methylprednisolone given every month as an add-on therapy to interferon beta or glatiramer acetate in patients with relapsing-remitting multiple sclerosis. PATIENTS AND METHODS: This was a multi-center, examiner-blinded, prospective study...
June 27, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28686948/posterior-communicating-artery-aneurysms-causing-facial-pain-a-comprehensive-review
#14
REVIEW
Javier Ros de San Pedro
Posterior communicating aneurysms are commonly associated with oculomotor nerve palsy. However, trigeminal nerve involvement among these aneurysms is a rare event with no previous analysis. In order to describe the main features of posterior communicating aneurysms causing trigeminal neuralgia (TGN-PComAAs) eight cases (six from the literature plus two more illustrative cases) were included in the present series. All cases were thoroughly studied in order to collect their epidemiological, radiological, clinical, therapeutic, pathogenic, and outcome data...
June 23, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28648954/fosphenytoin-induced-purple-glove-syndrome-a-case-report
#15
Joseph W Newman, Joseph R Blunck, Ronald K Fields, John E Croom
BACKGROUND: Purple glove syndrome (PGS) is a poorly understood severe adverse drug reaction that is typically associated with intravenous phenytoin administration. Although fosphenytoin is thought to circumvent this risk of PGS, we reveal a rare case of PGS in a patient treated with fosphenytoin therapy. CASE SUMMARY: A 71-year-old male with history of epilepsy was admitted for seizures and traumatic brain injury and intravenous fosphenytoin and levetiracetam were initiated...
June 19, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28668524/effects-of-dexmedetomidine-on-cd42a-cd14-hladr-cd14-and-inflammatory-cytokine-levels-in-patients-undergoing-multilevel-spinal-fusion
#16
Hongmei Zhou, Jian Lu, Yingyan Shen, Shuai Kang, Youming Zong
OBJECTIVE: To assess the effects of dexmedetomidine (Dex) on CD42a(+)/CD14(+),HLADR(+)/CD14(+) and inflammatory cytokine levels in patients undergoing multilevel spinal fusion. Patients and methods Forty ASA I-II patients undergoing multilevel spinal fusion were randomly divided into Dex and control groups (n=20). A continuous intravenous infusion of Dex (0.5μg/kg/h) or normal saline was started 10min prior to induction and was stopped 15min before operation completion. Serum levels of CD42a(+)/CD14(+), HLADR(+)/CD14(+), WBC, PLT, CRP, IL-6, IL-10, and TNF-α were measured before induction (T1), 30min (T2) after operation initiation, and 60min (T3), 1d (T4), 3d (T5), and 5d (T6) post-operation...
June 15, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28644969/premotor-symptoms-and-the-risk-of-parkinson-s-disease-a-case-control-study-in-mexican-population
#17
Mayela Rodríguez-Violante, Adib Jorge de Saráchaga, Amin Cervantes-Arriaga, Ned Merari Davila-Avila, Edith Carreón-Bautista, Ingrid Estrada-Bellmann, Guillermo Parra-López, Diego Cruz-Fino, Francisco Pascasio-Astudillo
OBJECTIVES: To assess the prevalence of pre-motor symptoms and estimate the risk for developing Parkinson's disease in Mexican population. PATIENTS AND METHODS: A case-control study was carried out with consecutive subjects with Parkinson's disease from two different referral centers in Mexico. Gender- and age-matched controls were randomly selected from the participating hospitals. All subjects were assessed using a structured questionnaire for the assessment of pre-motor symptoms (hyposmia, depression, anxiety, constipation, and sleep disorders)...
June 15, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28641127/deep-brain-stimulation-of-subthalamic-nucleus-helps-in-improving-late-phase-motor-planning-in-parkinson-s-disease
#18
Patil Ashlesh, Sood Sanjay Kumar, Kochhar Kanwal Preet, Goyal Vinay
OBJECTIVE: Deep brain stimulation of subthalamic nucleus (DBS-STN) is a well-accepted treatment for Parkinson's disease (PD) but its effect on motor planning in the disease is yet unclear. This study examines the effect of switching the stimulation ON and OFF on components of bereitschaftspotentials in PD. PATIENTS AND METHODS: Scalp bereitschaftspotentials were recorded during self-paced right wrist extensions at Fz, Cz, Pz, C3 and C4 sites in patients on DBS-STN plus medications (DBS-STN group) as treatment modality or on medications only (Med group) and compared with age matched healthy controls...
June 15, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28644968/serum-lipoprotein-associated-phospholipase-a2-predicts-the-formation-of-carotid-artery-plaque-and-its-vulnerability-in-anterior-circulation-cerebral-infarction
#19
Yuping Yang, Tao Xue, Juehua Zhu, Jiayi Xu, Xiaowei Hu, Penghao Wang, Tao Kong, Yan Yan, Lihui Yang, Shouru Xue
OBJECTIVE: Circulation inflammation markers such as high-sensitive C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) are considered as predictors of cerebral and cardiac vascular diseases. However, the role of hsCRP and Lp-PLA2 in the anterior circulation cerebral infarction (ACI) is to be elaborated. PATIENTS AND METHODS: We included 100 patients with acute anterior circulation cerebral infarction (AaCI group) and 50 non-infarction subjects (control group)...
June 12, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28622584/stmn1-as-a-candidate-gene-associated-with-atypical-meningioma-progression
#20
Haiyu Liu, Ye Li, Yunbo Li, Lixiang Zhou, Li Bie
OBJECTIVES: Meningiomas are the most common type of primary intracranial tumor. Atypical meningiomas are especially difficult to manage due to frequent disease recurrence. This study aimed to examine the role of stathmin (coded by the gene STMN1) as a factor in atypical meningioma recurrence. PATIENTS AND METHODS: A total of 59 sporadic atypical meningioma formalin-fixed paraffin-embedded (FFPE) samples were collected. The mRNA levels of the biomarker gene STMN1 were tested using quantitative RT-PCR...
June 10, 2017: Clinical Neurology and Neurosurgery
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