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Very long-term outcome of coronary covered stents. A report from the SCAAR registry.
EuroIntervention 2018 October 31
AIMS: To elucidate the short and long-term outcome of patients treated with covered stents compared to all other stented patients. Covered stents are mostly used for coronary perforations with high risk of early adverse events, but their long-term outcome are unknown.
METHODS AND RESULTS: The Swedish national registries from 2005 - 2017 disclosed 265 patients receiving 366 covered stents. Their outcomes were compared to all other 197 948 stented patients receiving 320 784 stents. Compared to regular stents, significant differences (p<0.001) between covered stents in short and long-term in respect to in-stent restenosis (ISR); target lesion revascularization (TLR); re-infarction (MI), Re-PCI and mortality, were all higher. The higher mortality was concentrated within the first month, as a landmark analysis at that time-point adjusted for age and procedural indication demonstrated no future difference in mortality, HR 1.02 (0.78-1.33) p=0.877. Stent thrombosis (ST) within one year were reported higher in covered stents than in other stents. However, no ST was reported in equine pericardial covered stents.
CONCLUSIONS: This observational study including the entire Swedish population shows patients receiving a covered stents have a significantly higher risk of all adverse events. Reassuring, long-term the mortality appears to be similar to other stented patients.
METHODS AND RESULTS: The Swedish national registries from 2005 - 2017 disclosed 265 patients receiving 366 covered stents. Their outcomes were compared to all other 197 948 stented patients receiving 320 784 stents. Compared to regular stents, significant differences (p<0.001) between covered stents in short and long-term in respect to in-stent restenosis (ISR); target lesion revascularization (TLR); re-infarction (MI), Re-PCI and mortality, were all higher. The higher mortality was concentrated within the first month, as a landmark analysis at that time-point adjusted for age and procedural indication demonstrated no future difference in mortality, HR 1.02 (0.78-1.33) p=0.877. Stent thrombosis (ST) within one year were reported higher in covered stents than in other stents. However, no ST was reported in equine pericardial covered stents.
CONCLUSIONS: This observational study including the entire Swedish population shows patients receiving a covered stents have a significantly higher risk of all adverse events. Reassuring, long-term the mortality appears to be similar to other stented patients.
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