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Konstantinos P Tsioufis, Lida Feyz, Kyriakos Dimitriadis, Dimitris Konstantinidis, Dimitrios Tousoulis, Michiel Voskuil, Felix Mahfoud, Joost Daemen
AIMS: To evaluate the safety and performance of renal nerve stimulation (RNS) for diagnostic mapping of the renal nerves. METHODS AND RESULTS: In this first-in-man study, twenty hypertensive patients underwent RNS using the ConfidenHT™ system. Bilateral stimulations were performed at 3 to 4 sites per artery at 2 and 4 mA. The primary endpoint was change in systolic blood pressure (SBP). Mean office blood pressure was 156/89 mmHg. No peri-procedural adverse events occurred...
September 18, 2018: EuroIntervention
Jun-Won Lee, Sang Wook Park, Jung-Woo Son, Sung-Gyun Ahn, Seung-Hwan Lee
AIMS: This study aimed to evaluate the feasibility and safety of the left distal transradial approach (ldTRA) as a default route for coronary angiography (CAG) and percutaneous coronary intervention (PCI). METHODS AND RESULTS: Between 11 Oct 2017 and 9 Jan 2018, 200 consecutive patients were enrolled in a single centre. The radial artery was punctured with a 20-gauge venipuncture catheter needle by three expert left radial approach operators. The success rates of arterial puncture, CAG, and PCI were 95...
September 18, 2018: EuroIntervention
Nicolas Amabile, Geraud Souteyrand, Pascal Motreff, Christophe Caussin
No abstract text is available yet for this article.
September 18, 2018: EuroIntervention
Alexandre Abizaid, Sasko Kedev, Elvin Kedhi, Suneel Talwar, Andrejs Erglis, Ota Hlinomaz, Monica Masotti, Farzin Fath-Ordoubadi, Pedro A Lemos, Krzysztof Milewski, Roberto Botelho, Ricardo Costa, Sripal Bangalore
AIMS: To evaluate the safety and efficacy of BioMime™ sirolimus-eluting coronary stent (SES) compared to the XIENCE family everolimus-eluting coronary stent (EES) in the treatment of patients with de novo native coronary artery lesions. METHODS AND RESULTS: The meriT-V is a prospective, multicenter, randomized, open-label, active-controlled, and non-inferiority trial. A total of 256 patients with up to two de novo native coronary artery lesions were enrolled and randomly assigned (2:1) to BioMime SES or XIENCE EES...
September 18, 2018: EuroIntervention
Eisuke Usui, Taishi Yonetsu, Yoshihisa Kanaji, Masahiro Hoshino, Masao Yamaguchi, Masahiro Hada, Rikuta Hamaya, Yoshinori Kanno, Tadashi Murai, Tetsumin Lee, Kenzo Hirao, Tsunekazu Kakuta
AIMS: We sought to investigate subclinical neoatherosclerotic changes and the healing response to sirolimus-eluting stents (SESs) to clarify the clinical safety and the neointimal pathology of SESs more than 10 years after implantation. METHODS AND RESULTS: We investigated a total of 180 SESs without stent failure in 103 patients who underwent optical coherence tomography (OCT) examination of stented vessels more than 5 years after implantation. We assessed the presence or absence of neoatherosclerosis and the healing process by OCT and compared the results between stents at 5 to 10 years after implantation (Group A, 114 stents with 19,873 struts) and stents more than 10 years after implantation (Group B, 66 stents with 10,937 struts)...
September 18, 2018: EuroIntervention
Fernando Macaya, Pablo Salinas, Nieves Gonzalo, Santiago J Camacho-Freire, Robert Jackson, Montse Massot, María R Ortas-Nadal, Ángel Sánchez-Recalde, José F Díaz-Fernández, José Moreu, David Adlam, Javier Escaned
No abstract text is available yet for this article.
September 18, 2018: EuroIntervention
Jean-Michel Paradis, Tamim M Nazif, Josep Rodés-Cabau
No abstract text is available yet for this article.
September 18, 2018: EuroIntervention
Laurens J C Van Zandvoort, Dariusz Dudek, Joachim Weber-Albers, Alexandre Abizaid, Evald Høj Christiansen, David W M Muller, Janusz Kochman, Łukasz Kołtowski, Jens Lassen, Roman Wojdyla, Joanna J Wykrzykowska, Yoshinobu Onuma, Joost Daemen
AIMS: FANTOM II is a prospective multicenter trial assessing the safety and efficacy of the Fantom Sirolimus-Eluting Bioresorbable Coronary Scaffold (BRS). The present substudy focuses on the 6 and 9 months IVUS findings. METHODS AND RESULTS: A total of 240 patients with de novo coronary artery lesions presenting with stable or unstable disease were included in 2 sequential cohorts (cohort A (n=117) and B (n=123) in which angiographic follow-up was performed at either 6 or 9 months respectively...
September 18, 2018: EuroIntervention
Fernando Alfonso, Javier Cuesta, Marcos García-Guimaraes, Fernando Rivero
No abstract text is available yet for this article.
September 4, 2018: EuroIntervention
Giovanna Sarno, Alaide Chieffo, Peter Ludman, Adam Witkowski, Christian Spaulding, Stefan James
No abstract text is available yet for this article.
September 4, 2018: EuroIntervention
Robert Schueler, Rasha Al-Lamee, Felix Mahfoud, Davide Capodanno, Mirvat Al Asnag, Michael Haude
No abstract text is available yet for this article.
September 4, 2018: EuroIntervention
Ana Belen Cid Alvarez, Fernando Gomez-Peña, Alfredo Redondo-Dieguez, Alejandro Avila, Diego López, Xoan Sanmartin, Jose R González-Juanatey, Ramiro Trillo-Nouche
AIMS: This study aimed to investigate the prognostic impact of the SYNTAX II score (SS-II) of ST-segment elevation myocardial infarction (STEMI) patients undergoing a primary percutaneous coronary intervention (pPCI). METHODS AND RESULTS: This retrospective cohort study included 1689 patients with STEMI who underwent pPCI between January 2008 and December 2016. The patients were categorized into three groups based on SS-II tertiles [SS-II low tertile < 24 (n=585), 25 ≤SS-II intermediate tertile ≤ 33 (n=567), and SS-II high tertile > 34 (n=537)]...
September 4, 2018: EuroIntervention
Claudia Tiburtius, Julian Witt, Joachim Schofer
No abstract text is available yet for this article.
September 4, 2018: EuroIntervention
Christina Brinkmann, Amnon Eitan, Carsten Schwencke, Detlef G Mathey, Joachim Schofer
AIMS: To determine the feasibility of Rotational Atherectomy (RA) in chronic total occlusion (CTO)-PCI and compare success- and complication rates of RA in CTO-lesions versus non-occluded lesions. Data on RA in CTO is rare and it is unknown how procedural success and risk of RA in CTO-lesions compare to RA in non-CTO-lesions. METHODS AND RESULTS: RA was performed in 392 out of 17919 PCI procedures (2.2% of PCI cohort) and classified as RA-CTO (n=75) and RA-non-CTO (n=317)...
September 4, 2018: EuroIntervention
Roberto Nerla, Antonio Micari, Fausto Castriota, Eligio Miccichè, Maria Antonella Ruffino, Gianmarco de Donato, Carlo Setacci, Alberto Cremonesi
No abstract text is available yet for this article.
September 4, 2018: EuroIntervention
Christian Pristipino, Horst Sievert, Fabrizio D'Ascenzo, Jean-Louis Mas, Bernhard Meier, Paolo Scacciatella, David Hildick-Smith, Fiorenzo Gaita, Danilo Toni, Paul Kyrle, John Thomson, Geneviève Derumeaux, Eustaquio Onorato, Dirk Sibbing, Peter Germonpré, Sergio Berti, Massimo Chessa, Francesco Bedogni, Dariusz Dudek, Marius Hornung, Jose Zamorano
The presence of a patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions; however, the subject remains controversial and no official statements have been published. This interdisciplinary paper, prepared with involvement of eight European scientific societies, aims to review the available trial evidence and to define the principles needed to guide decision making in patients with PFO. In order to guarantee a strict process, position statements were developed with the use of a modified grading of recommendations assessment, development, and evaluation (GRADE) methodology...
August 25, 2018: EuroIntervention
Neil P Fam, Sondos Samargandy, Sumeet Gandhi, Janine Eckstein
No abstract text is available yet for this article.
August 21, 2018: EuroIntervention
Francesco Maisano, Stephen Worthley, Josep Rodés-Cabau, Axel Hans-Peter Linke, Stephan Fichtlscherer, Ulrich Schäfer, Raj R Makkar, Gregory Fontana, Federico M Asch, Lars Søndergaard
AIMS: The aim of this study was to investigate the procedural and short-term outcomes of transcatheter aortic valve implantation (TAVI) with the Portico™ self-expanding, resheathable TAVI system from an ongoing long-term multicentre study. METHODS AND RESULTS: A total of 941 patients (82.4±5.9 years, 65.7% female, STS score 5.8±4.9%) with severe symptomatic aortic stenosis underwent TAVI using the Portico bioprosthesis. Patients were clinically and echocardiographically assessed at implantation, discharge and 30 days post TAVI...
August 17, 2018: EuroIntervention
Andreas Schaefer, Edith Lubos, Jan Benjamin Pietzsch, Malte Pietzsch, Simon Weber, Stefan Blankenberg, Hermann Reichenspurner, Ulrich Schäfer, Lenard Conradi
AIMS: The German healthcare system was among the first to introduce transcatheter mitral valve repair (TMVR) in routine care. Objective of this study was to analyze adoption and utilization patterns and to estimate impact of TMVR availability on mitral valve (MV) procedure volumes in the first 8 years after commercialization. METHODS AND RESULTS: Procedure volumes were collected from German Federal Statistics Office databases for TMVR and mitral valve surgery (MVS) from 2008-2015...
August 14, 2018: EuroIntervention
Shmuel Chen, Björn Redfors, Yangbo Liu, Ori Ben-Yehuda, Marie-Claude Morice, Martin B Leon, David E Kandzari, Roxana Mehran, Nicholas J Lembo, Adrian P Banning, Béla Merkely, A Pieter Kappetein, Joseph F Sabik, Patrick W Serruys, Gregg W Stone
AIMS: We sought to compare clinical outcomes and procedural characteristics with transradial access (TRA) versus transfemoral access (TFA) in patients who were treated with PCI for left main coronary artery (LM) coronary artery disease. METHODS AND RESULTS: The EXCEL trial was a prospective, international, open-label, multicenter trial that randomized 1905 patients with LM disease and SYNTAX scores ≤32 to PCI with everolimus-eluting stents versus coronary artery bypass grafting...
August 14, 2018: EuroIntervention
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