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https://www.readbyqxmd.com/read/28089953/transcatheter-treatment-of-severe-tricuspid-regurgitation-using-the-edge-to-edge-repair-technique
#1
Daniel Braun, Michael Nabauer, Mathias Orban, Martin Orban, Lisa Gross, Andrea Englmaier, Diana Rösler, Julinda Mehilli, Axel Bauer, Christian Hagl, Steffen Massberg, Jörg Hausleiter
AIMS: The aim of this study was to investigate the procedural feasibility and short-term durability of the transcatheter tricuspid valve edge-to-edge repair technique in highly symptomatic patients with severe tricuspid regurgitation (TR). METHODS AND RESULTS: Eighteen consecutive patients suffering from severe right-sided heart failure (NYHA Class III-IV), primarily due to moderate to severe tricuspid regurgitation, were included in the study. Applying a modified steering technique for the clip delivery system, six patients were treated for isolated severe TR, while 12 patients were treated for moderate to severe TR and concomitant severe mitral regurgitation...
January 17, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28089952/impact-of-tricuspid-valve-regurgitation-in-surgical-high-risk-patients-undergoing-mitraclip-implantation-results-from-the-trami-registry
#2
Daniel Kalbacher, Ulrich Schäfer, R Stephan Von Bardeleben, Christine S Zuern, Raffi Bekeredjian, Taoufik Ouarrak, Horst Sievert, Georg Nickenig, Peter Boekstegers, Jochen Senges, Wolfgang Schillinger, Edith Lubos
AIMS: We sought to assess the impact of TR severity on patient outcome in a collective with relevant mitral regurgitation undergoing MitraClip implantation. METHODS AND RESULTS: From 08/2010-07/2013, 766 patients (age 75.3±8.5 years, 61% male gender, median EuroSCORE 24.3%±18.4) were prospectively enrolled in the TRAMI registry and stratified by echocardiography in no/mild, moderate and severe TR. Overall, the mean of implanted MitraClips was higher in patients with severe TR but increasing TR severity was not associated with procedural success...
January 17, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28067200/quantitative-angiography-methods-for-bifurcation-lesions-a-consensus-statement-update-from-the-european-bifurcation-group
#3
Carlos Collet, Yoshinobu Onuma, Rafael Cavalcante, Maik Grundeken, Philippe Généreux, Jeffrey Popma, Ricardo Costa, Goran Stankovic, Shengxian Tu, Johan H C Reiber, Jean-Paul Aben, Jens Flensted Lassen, Yves Louvard, Alexandra Lansky, Patrick W Serruys
Bifurcation lesions represent one of the most challenging lesions subset in interventional cardiology. The European Bifurcation Club (EBC) is an academic consortium whose goal has been to assess and recommend the appropriate strategies to manage bifurcation lesions. The quantitative coronary angiography (QCA) methods for the evaluation of bifurcation lesions has been subject to extensive research. Single vessel quantitative coronary angiography (QCA) has shown to be inaccurate to assess bifurcation lesions dimensions...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28067199/ct-in-patients-with-tricuspid-regurgitation-prior-to-transcatheter-valve-repair-dynamic-analysis-of-the-annulus-with-an-individually-tailored-contrast-media-protocol
#4
Ricarda Hinzpeter, Matthias Eberhard, Philipp Burghard, Felix C Tanner, Maurizio Taramasso, Robert Manka, Gudrun Feuchtner, Francesco Maisano, Hatem Alkadhi
AIMS: To introduce a contrast media (CM)-protocol for the dynamic visualization of the tricuspid valve (TV) and tricuspid annulus (TA) with CT. METHODS AND RESULTS: Fifteen patients with no cardiac abnormalities (=controls), 15 patients with functional tricuspid regurgitation (FTR) <3+ and 13 patients with FTR ≥3+ underwent a dedicated cardiac CT protocol. Using an advanced visualization, segmentation and analysis software, the annular area, entire annular circumference, its three parts, and annular diameters were measured by two independent, blinded readers...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28067198/outcomes-of-patients-treated-with-durable-polymer-platinum-chromium-everolimus-eluting-stents-a-meta-analysis-of-randomized-trials
#5
Salvatore Cassese, Gjin Ndrepepa, Robert A Byrne, Sebastian Kufner, Erion Xhepa, Antoinette de Waha, Tobias Rheude, Roisin Colleran, Daniele Giacoppo, Yukinori Harada, Karl-Ludwig Laugwitz, Heribert Schunkert, Massimiliano Fusaro, Adnan Kastrati
AIMS: The durable-polymer platinum-chromium everolimus-eluting stent (PtCr-EES) is a new- generation drug-eluting stent (DES) with a platinum-enriched metallic platform developed to improve the percutaneous treatment of patients with coronary artery disease. We sought to investigate the performance of durable-polymer PtCr-EES versus other new-generation DES. METHODS AND RESULTS: We undertook a meta-analysis of trials, in which patients receiving percutaneous coronary intervention (PCI) were randomly assigned to durable-polymer PtCr-EES versus other new-generation DES (other DES)...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28067197/comparison-of-procedural-and-clinical-outcomes-with-evolut-r-versus-medtronic-corevalve-a-swiss-tavi-registry-analysis
#6
Stephane Noble, Stefan Stortecky, Dik Heg, David Tuller, Raban Jeger, Stefan Toggweiler, Enrico Ferrari, Fabian Nietlispach, Maurizio Taramasso, Francesco Maisano, Jürg Grünenfelder, Peter Jüni, Christoph Huber, Thierry Carrel, Stephan Windecker, Peter Wenaweser, Marco Roffi
AIMS: Data on procedural and clinical outcomes after transcatheter aortic valve implantation (TAVI) with the new generation self-expanding Medtronic Evolut-R prosthesis in comparison with its predecessor, the Medtronic CoreValve, are scarce. METHODS AND RESULTS: In a nationwide, prospective, multi-center cohort study outcomes of consecutive transfemoral TAVI patients treated with the new- generation Medtronic Evolut-R (September 2014 - February 2016) and the Medtronic CoreValve (February 2011 - February 2016) were investigated...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28067196/management-of-st-elevation-myocardial-infarction-in-young-patients-by-limiting-implantation-of-durable-intracoronary-devices-and-guided-by-optical-frequency-domain-imaging-proof-of-concept-study
#7
Nicolas Combaret, Géraud Souteyrand, Nicolas Barber-Chamoux, Guilhem Malcles, Aimé Amonchot, Bruno Pereira, Louis Le Bivic, Romain Eschalier, Romain Trésorier, Pascal Motreff
AIMS: To demonstrate the feasibility and safety of ST-elevation myocardial infarction (STEMI) management in young patients by limiting implantation of durable intracoronary devices (using bioresorbable stent or medical treatment alone). METHODS AND RESULTS: Patients <50 years admitted for STEMI with single vessel disease received a two-stage management strategy. During a second coronary angiography performed between day 2 and day 7, optical frequency domain imaging (OFDI) enabled to guide therapeutic management: i) in the case of a stenosis greater that 70% or plaque prolapse, implantation of a BVS; ii) in the other cases, continuation of medical management alone without stenting...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28067195/combined-erythropoietin-and-iron-therapy-for-anemic-patients-undergoing-transcatheter-aortic-valve-replacement-the-epicure-randomized-clinical-trial
#8
Marina Urena, Maria Del Trigo, Omar Abdul-Jawad Altisent, Francisco Campelo-Prada, Ander Regueiro, Robert DeLarochellière, Daniel Doyle, Siamak Mohammadi, Jean-Michel Paradis, François Dagenais, Eric Dumont, Rishi Puri, Vincent Laroche, Josep Rodés-Cabau
AIMS: The aim of this study was to evaluate, in anemic patients, the efficacy of erythropoietin (EPO) in reducing red-cell (RC) transfusion rates post-TAVI. METHODS AND RESULTS: This was a randomized double-blind trial. Patients with severe symptomatic aortic stenosis and concomitant anemia with an indication for TAVI were randomized (1:1) to receive 2 weight-based doses of EPO (darbepoetin alfa) + iron or placebo at days 10 (±4 days) and 1 (±1 day) pre- TAVI...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28044990/unfractionated-heparin-versus-bivalirudin-in-patients-undergoing-primary-percutaneous-coronary-intervention-a-swedeheart-study
#9
Per Grimfjärd, David Erlinge, Sasha Koul, Bo Lagerqvist, Bodil Svennblad, Christoph Varenhorst, Stefan K James
AIMS: To compare outcome in unfractionated heparin (UFH) and bivalirudin treated patients undergoing primary percutaneous coronary intervention (PPCI). METHODS AND RESULTS: This observational study contained 20,614 PPCI patients treated with either UFH monotherapy or bivalirudin with or without concomitant UFH. Patients with oral anticoagulant or glycoprotein IIb/IIIa-inhibitor (GPI) treatment were excluded. The primary outcome measure was definite early stent thrombosis (ST) that occurred at low and similar rates in UFH only and bivalirudin treated patients: 0...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28044989/surgical-mitral-valve-replacement-with-melody-valve-in-infants-and-children-the-italian-experience
#10
Alessandro Frigiola, Francesca Romana Pluchinotta, Antonio Saracino, Alessandro Giamberti, Carmelo Arcidiacono, Luciane Piazza, Matteo Reali, Gianfranco Butera, Alessandro Varrica, Mario Carminati
AIMS: Paediatric patients with mitral valve (MV) disease have limited options for prosthetic MV replacement. Based on a long experience with the stented bovine jugular vein graft (Melody Valve) in the right ventricular outflow tract, we tested the use of the Melody Valve as a surgical implant in the mitral position in patients with congenital mitral disease. METHODS AND RESULTS: Eight patients, age 3 months to 6.2 years, with congenital MV dysplasia had undergone Melody valve implantation in mitral position between March 2014 and October 2015...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28044988/feasibility-of-concomitant-mitraclip-and-left-atrial-appendage-occlusion
#11
Shingo Kuwata, Maurizio Taramasso, Michel Zuber, Gabor Suetsch, Adrian Attinger-Toller, David Wicki, Francesco Maisano, Fabian Nietlispach
AIMS: The aim of our study is to report our single center experience with concomitant MitraClip (MC) and left atrial appendage occlusion (LAAO) and to further assess feasibility, safety and short term outcome of such an approach. METHODS AND RESULTS: Twenty-five consecutive patients underwent MC with concomitant LAAO at our hospital (combined group). As a control group, 25 consecutive patients with atrial fibrillation (AF) undergoing standalone MC were selected...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28044987/drug-eluting-stents-versus-bare-metal-stents-for-the-prevention-of-restenosis-in-patients-with-renovascular-disease
#12
Christian Bradaric, Kristin Eser, Stephanie Preuss, Michael Dommasch, Isabell Wustrow, Nicolas Langwieser, Bernhard Haller, Ilka Ott, Massimiliano Fusaro, Uwe Heemann, Karl-Ludwig Laugwitz, Adnan Kastrati, Tareq Ibrahim
AIMS: To assess the impact of drug-eluting stents (DES) compared to bare-metal stents (BMS) for the endovascular treatment of atherosclerotic renal artery stenosis (ARAS). METHODS AND RESULTS: We retrospectively evaluated all of our endovascular BMS- and DES-implantations performed in de- novo ARAS between 2000-2014 at our institution. The occurrence of in-stent restenosis (ISR) detected by ultrasound or angiography, kidney function, blood pressure (BP), and the number of antihypertensive drugs were analyzed as endpoints...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28044986/ischemic-and-bleeding-outcomes-in-elderly-patients-undergoing-a-prolonged-versus-shortened-duration-of-dual-antiplatelet-therapy-after-percutaneous-coronary-intervention-insights-from-the-prodigy-randomized-trial
#13
Raffaele Piccolo, Giulia Magnani, Sara Ariotti, Giuseppe Gargiulo, Marcello Marino, Andrea Santucci, Anna Franzone, Matteo Tebaldi, Dik Heg, Stephan Windecker, Marco Valgimigli
AIMS: To evaluate the efficacy and safety of 24-month vs. 6-month dual antiplatelet therapy (DAPT) among elderly (≥75 years) and non-elderly patients (<75 years) undergoing percutaneous coronary intervention. METHODS AND RESULTS: The primary efficacy endpoint of the PRODIGY trial was the composite of death, myocardial infarction, or cerebrovascular accident at 24-month follow-up. The key safety endpoint was type 2, 3 or 5 bleeding according to the BARC criteria...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28044985/radiation-dose-absorbed-by-operators-during-transradial-percutaneous-coronary-procedures-comparing-different-protective-drapes-the-radiation-study
#14
Alessandro Sciahbasi, Stefano Rigattieri, Alessandro Sarandrea, Maria Cera, Cristian Di Russo, Silvio Fedele, Silvio Romano, Francesco Rocco Pugliese, Maria Penco
AIMS: To compare different radiation protection drapes in term of radiation dose absorbed by operators during right or left transradial procedures. METHODS AND RESULTS: Patients who underwent transradial coronary procedures were randomized initially in 4 groups: Group 1 (no drapes), Group 2 (drape on patient's arm), Group 3 (pelvic drape), Group 4 (combined arm and pelvic drapes). Subsequently each group was further randomized to right or left radial access. The primary end-point was the operator radiation dose at thorax...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28044984/serial-quantitative-magnetic-resonance-angiography-follow-up-of-renal-artery-dimensions-following-treatment-by-four-different-renal-denervation-systems
#15
Laurens van Zandvoort, Matthijs van Kranenburg, Antonios Karanasos, Nicolas Van Mieghem, Mohammed Ouhlous, Robert-Jan van Geuns, Ron van Domburg, Joost Daemen
AIMS: Renal sympathetic denervation (RDN) is being studied as a therapeutic option for patients with therapy resistant hypertension. It remains unclear if the procedure affects the renal arteries in such a way that luminal narrowing might occur at the mid- to longer-term. METHODS AND RESULTS: In a prospective cohort of 27 patients referred for RDN, quantitative magnetic resonance angiography (MRA) was used to assess 52 vessels at baseline, 6-, and 12 months post treatment with one out of four different devices...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28044983/chronic-total-occlusion-in-non-infarct-related-artery-is-closely-associated-with-increased-five-year-mortality-in-patients-with-st-segment-elevation-acute-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention-from-the-credo-kyoto-ami-registry
#16
Hiroki Watanabe, Takeshi Morimoto, Hiroki Shiomi, Yutaka Furukawa, Yoshihisa Nakagawa, Kenji Ando, Kazushige Kadota, Takeshi Kimura
AIMS: We sought to investigate the clinical impact of chronic total occlusion (CTO) in non-infarct-related artery (IRA) on long-term cardiovascular outcomes in patients with ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS: Among 5429 patients enrolled in the CREDO-Kyoto AMI registry, the current study population consisted of 2045 STEMI patients with multi-vessel disease (MVD) who underwent primary PCI within 24 hours after the symptom onset. The cumulative 5-year, 30-day and 30-day-to-5-year incidences of all-cause death were all significantly higher in the CTO group than in the non-CTO group (37...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/27993758/first-in-man-6-month-results-of-qvanteq-surface-modified-coronary-stent-system-in-native-coronary-stenosis
#17
Pannipa Suwannasom, Yohei Sotomi, Roberto Corti, David J Kurz, Marco Roffi, Clemens von Birgelen, Stefano Buzzi, Arik Zucker, Jouke Dijkstra, Joanna J Wykrzykowska, Robbert J de Winter, Stephan Windecker, Yoshinobu Onuma, Patrick W Serruys, Joost Daemen, Lorenz Räber
AIMS: In pre-clinical studies, a bare metal cobalt-chromium stent with an active surface oxide layer modification (BMSmod) has shown to effectively inhibited neointimal hyperplasia. We sought to assess both clinical safety and feasibility of the BMSmod. METHODS AND RESULTS: In this prospective, nonrandomized, first-in-man multicenter study, a total of 31 patients with de novo coronary lesions, reference lumen diameters of 2.5 - 3.5 mm and lesion length ≤16 mm were enrolled...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27993757/percutaneous-intervention-in-chronic-total-coronary-occlusions-caused-by-in-stent-restenosis-procedural-results-and-long-term-clinical-outcomes-in-the-toro-spanish-registry-of-chronic-total-occlusion-secondary-to-an-occlusive-in-stent-restenosis-multicenter
#18
José M de la Torre Hernandez, José R Rumoroso, Asier Subinas, Nieves Gonzalo, Soledad Ojeda, Manuel Pan, Victoria Martín Yuste, Alfonso Suárez, Felipe Hernández, Luis Teruel, José Moreu, José M Cubero, José D Cascón, Hugo Vinhas, Íñigo Lozano, Javier Martin Moreiras, Armando Pérez de Prado, Javier Goicolea, Javier Escaned
AIMS: Limited data exist on the treatment and outcomes of patients with chronic total occlusions due to in-stent restenosis (CTO-ISR). We sought to evaluate results and clinical outcomes in percutaneous interventions over CTO-ISR. METHODS AND RESULTS: Registry in 16 centers involving consecutive patients undergoing attempt of percutaneous intervention over CTO-ISR. A total of 233 patients were included, 192 (82.4%) with successful acute result. Success rate was significantly lower in patients with: lesion in circumflex artery, ostial lesion, J score > 3 and no femoral access...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27993756/change-in-lumen-eccentricity-and-asymmetry-after-treatment-with-absorb-bioresorbable-vascular-scaffolds-in-the-absorb-cohort-b-trial-a-five-year-serial-optical-coherence-tomography-imaging-study
#19
Pannipa Suwannasom, Yohei Sotomi, Taku Asano, Jaryl Ng Chen Koon, Hiroki Tateishi, Yaping Zeng, Erhan Tenekecioglu, Joanna J Wykrzykowska, Nicolas Foin, Robert J de Winter, John A Ormiston, Patrick W Serruys, Yoshinobu Onuma
AIMS: To investigate long-term changes in lumen eccentricity and asymmetry at 5 years after implantation of the bioresorbable vascular scaffold (BVS). METHODS AND RESULTS: Out of 101 patients from Absorb cohort B trial, 28 patients(29 lesions) with serial Optical Coherence Tomography(OCT) examination at 4 different time points(Cohort B1: post-procedure,6 months, 2, and 5 years[n=13]; Cohort B2:post-procedure,1, 3, and 5 years[n=16]) were evaluated. The longitudinal variance in lumen diameter was assessed by asymmetry index(AI)...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27993755/clinical-angiographic-ivus-and-oct-predictors-for-irregular-protrusion-after-coronary-stenting
#20
Krzysztof L Bryniarski, Seung-Jea Tahk, So-Yeon Choi, Tsunenari Soeda, Takumi Higuma, Erika Yamamoto, Lei Xing, Jiannan Dai, Thomas Zanchin, Hang Lee, Ik-Kyung Jang
AIMS: Irregular protrusion identified by optical coherence tomography (OCT) immediately following stent implantation has been reported as an independent predictor for adverse cardiac events at 1 year. However, baseline characteristics for development of irregular protrusion are unknown. The aim of the study was to identify predictors for irregular protrusion following stent implantation. METHODS AND RESULTS: A total of 900 lesions in 786 patients who had post-stent OCT imaging were analyzed...
December 20, 2016: EuroIntervention
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