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Ole Kristian Møller-Helgestad, Janus A Hyldebrandt, Ann Banke, Charlotte S Rud, Nanna L J Udesen, Louise Linde, Lisette Okkels-Jensen, Henrik Schmidt, Hanne B Ravn, Jacob E Møller
Aims/ To evaluate ImpellaCP over Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) and their impact on left ventricular (LV) unloading and end-organ perfusion. Methods and results: cardiogenic shock (CS) was induced by injecting microspheres into the left coronary artery in fourteen adult female swine. ImpellaCP or VA-ECMO was initiated in the presence of CS and evaluated after 60 minutes. LV pressure-volume area (PVA, total mechanical work) was obtained from a conductance catheter. Results are presented as mean [95% CI] and rank sum test was used to assess differences between devices...
November 13, 2018: EuroIntervention
Niklas Schofer, Florian Deuschl, Nicole Rübsamen, Johanna Skibowski, Moritz Seiffert, Lisa Voigtländer, Andreas Schaefer, Yvonne Schneeberger, Johannes Schirmer, Hermann Reichenspurner, Stefan Blankenberg, Lenard Conradi, Ulrich Schäfer
AIMS: We aimed to assess prevalence and features of PPM following transcatheter aortic valve implantation (TAVI) and its prognostic impact considering baseline left ventricular ejection fraction (LVEF). METHODS AND RESULTS: Data from 1,309 patients undergoing TAVI for severe aortic stenosis was derived from a single-center dedicated TAVI registry. PPM was assessed according to echocardiography at discharge and was defined in accordance with VARC2. Follow-up time was 2...
November 13, 2018: EuroIntervention
Jeremías Bayón, Melisa Santás-Álvarez, Raymundo Ocaranza-Sánchez, Carlos González-Juanatey
No abstract text is available yet for this article.
November 13, 2018: EuroIntervention
Francisco J Morales-Ponce, Francisco J Lozano-Cid, Pedro Martinez-Romero, Pablo Gonzalez-Perez, Juan A Sanchez-Brotons, Isabel Diaz-Torres, Juan C Rodriguez-Yanez, Pilar Caro-Mateo, Ana M Serrador-Frutos
AIMS: We sought to compare the effects of intracoronary administration of a fibrinolytic drug (tenecteplase) to those of a glycoprotein IIb/IIIa inhibitor (abciximab) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). METHODS AND RESULTS: In this pilot trial, 76 patients (59 male) with anterior STEMI were randomised to intracoronary infusion of reduced-dose tenecteplase or abciximab during PPCI...
November 13, 2018: EuroIntervention
Sebastien Hascoet, Robert Dalla Pozza, Jamie Bentham, Ronald Giacomo Carere, Majed Kanaan, Peter Ewert, Elzbieta Katarzyna Biernacka, Oliver Kretschmar, Cornelia Deutsch, Florence Lecerf, Anja Lehner, Marinos Kantzis, Jana Kurucova, Martin Thoenes, Peter Bramlage, Nikolaus A Haas
AIMS: Multiple surgical revisions are often necessary in individuals with congenital heart defects affecting the RVOT or pulmonary valve. There are no multicentre data on the feasibility and safety of percutaneous pulmonary valve implantation using the SAPIEN 3 (S3) transcatheter heart valve. METHODS AND RESULTS: Pulmonic S3 is an observational registry of patients undergoing PPVI with the S3 valve across centres in Europe and Canada. Data for 82 patients (mean age 27...
November 13, 2018: EuroIntervention
Vlasis Ninios, Christos Tourmousoglou, Silvia Jancovici, Julian Kalin
No abstract text is available yet for this article.
November 6, 2018: EuroIntervention
Luis Cressa, David Hildick-Smith, Alejandro Herrara, Fabian Ruiz
No abstract text is available yet for this article.
November 6, 2018: EuroIntervention
Yuki Katagiri, Yoshinobu Onuma, Taku Asano, Andres Iñiguez, Lisette Okkels Jensen, Àngel Cequier, Sjoerd H Hofma, Evald Høj Christiansen, Maarten Suttorp, Salvatore Brugaletta, Lorenz Räber, Manel Sabaté, Stephan Windecker, Patrick W Serruys
No abstract text is available yet for this article.
November 6, 2018: EuroIntervention
Hirofumi Hioki, Salvatore Brugaletta, Kohki Ishida, Gianluca Campo, Simone Biscaglia, Luis Ortega-Paz, Bernardo Cortese, Attilio Varricchio, Azeem Latib, Manel Sabaté, Maurizio Tespili, Alfonso Ielasi
AIMS: To evaluate the impact of bioresorbable vascular scaffold (BRS) implantation technique on post-procedural quantitative coronary angiography (QCA) parameters in ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS: We assessed 442 STEMI patients who underwent BRS implantation in the BVS STEMI STRATEGY-IT study. Optimal BRS implantation was assessed using PSP-score, developed and validated in the GHOST-EU registry. We analyzed post-implantation QCA parameters, including minimum lumen diameter (MLD) and maximum footprint, in patients with and without optimal BRS implantation, coded as maximum PSP score...
November 6, 2018: EuroIntervention
Yuki Katagiri, Patrick W Serruys, Taku Asano, Yosuke Miyazaki, Ply Chichareon, Rodrigo Modolo, Kuniaki Takahashi, Norihiro Kogame, Joanna J Wykrzykowska, Jan J Piek, Yoshinobu Onuma
Absorb bioresorbable scaffold (BRS), the most studied device among all BRS, suffered a major setback following the negative results of the ABSORB trials. However, approximately 34 BRSs from 22 companies are currently under development. The potential device specific factors related to increased event rate in Absorb were: 1) weaker mechanical properties, 2) larger strut thickness (less embedment and larger protrusion) and width (larger footprint) predisposing to underexpansion / protrusion of strut, eventually resulting in increased thrombogenicity, and 3) longer bioresorption time combined with failure of encapsulation of struts before dismantling process ensues...
November 6, 2018: EuroIntervention
Yohei Sotomi, Satoshi Suzuki, Tomoaki Kobayashi, Yuma Hamanaka, Shimpei Nakatani, Akio Hirata, Yasuharu Takeda, Yasunori Ueda, Yasushi Sakata, Yoshiharu Higuchi
AIMS: We aimed to test the hypothesis that presence of in-stent yellow plaque (YP) assessed by angioscopy would be a risk of very late stent failure (VLSF) of the cobalt chromium everolimus-eluting stent (CoCr-EES) in comparison with first-generation drug-eluting stents (DES). METHODS AND RESULTS: The DESNOTE-X study was a prospective cohort study, an extended study of the DESNOTE (UMIN000013515). All patients who received successful angioscopic examination at planned 1-year follow-up of DES were clinically followed...
November 6, 2018: EuroIntervention
Daxin Zhou, Wenzhi Pan, Hasan Jilaihawi, Gejun Zhang, Yuan Feng, Xin Pan, Jinfen Liu, Shiqiang Yu, Qiling Cao, Junbo Ge
AIMS: To assess the safety and efficacy of the Venus p-valve. METHODS AND RESULTS: Patients who had moderate or severe pulmonary regurgitation after surgical repair of the right ventricular outflow tract (RVOT) with a transannular or RVOT patch were included in the study. Fifty-five patients (67% female; average age 28.7±12.4 years) from 6 different hospitals in China were enrolled. The procedure success rate was 98.2%. One patient experienced valve dislodgement two days after the procedure...
November 6, 2018: EuroIntervention
Linying Xia, Yi Liu, Haitao Liu, Ling Tao
No abstract text is available yet for this article.
November 6, 2018: EuroIntervention
Tobias Wengenmayer, Christoph Bode, Manfred Zehender, Sebastian Grundmann
No abstract text is available yet for this article.
October 30, 2018: EuroIntervention
Rod H Stables, Mostafa Elguindy, Ian Kemp, Zoe Nicholas, Christine Mars, Liam Mullen, Nick Curzen
AIMS: We examined the relative performance of the new COMET wire from Boston Scientific (BS), and the established technology from St Jude/Abbott Vascular (SJ). METHODS AND RESULTS: We compared simultaneous readings from pairs of wires. Patients were randomised to one of three groups, BS/BS; SJ/SJ; SJ/BS. The latter group were sub-randomised to specify the wire passed first. After pressure equalisation at the guide catheter, we recorded paired observations in sequence: (a) distal to proximal pressure ratio at baseline; (b) FFR at maximum hyperaemia; (c) pressure on withdrawal into the guide catheter to quantify "drift"...
October 30, 2018: EuroIntervention
Hiroyuki Jinnouchi, Hiroyoshi Mori, Qi Cheng, Matthew Kutyna, Sho Torii, Atsushi Sakamoto, Liang Guo, Eduardo Acampado, Anuj Gupta, Frank D Kolodgie, Renu Virmani, Aloke V Finn
AIMS: To investigate the COBRA-PzF stent (C-PzF) with respect to thrombogenicity and healing versus conventional drug-eluting stents (DES) in dedicated preclinical models to evaluate their suitability for short-term dual anti-platelet therapy (DAPT). METHODS AND RESULTS: To examine acute thrombogenicity, C-PzF, durable polymer drug-eluting stent (DP-DES), and bioabsorable polymer DES (BP-DES) were compared in a porcine arteriovenous shunt model and in a rabbit model to evaluate endothelial coverage at 14 days...
October 30, 2018: EuroIntervention
Jan Harnek, Stefan K James, Bo Lagerqvist
AIMS: To elucidate the short and long-term outcome of patients treated with covered stents compared to all other stented patients. Covered stents are mostly used for coronary perforations with high risk of early adverse events, but their long-term outcome are unknown. METHODS AND RESULTS: The Swedish national registries from 2005 - 2017 disclosed 265 patients receiving 366 covered stents. Their outcomes were compared to all other 197 948 stented patients receiving 320 784 stents...
October 30, 2018: EuroIntervention
Antonio Mangieri, Alaide Chieffo, Won-Keun Kim, Giulio G Stefanini, Giuseppe Rescigno, Marco Barbanti, Corrado Tamburino, Andreas Rück, Matteo Pagnesi, Rickard Linder, Stefan Toggweiler, Matteo Montorfano, Antonio Colombo
AIMS: to assess the performance of a self-expandable valve in bicuspid aortic valves (BAV) stenosis. METHOD AND RESULTS: an international multicentre registry included a total of 712 patients with aortic stenosis treated with ACURATE neo in both bicuspid (n=54%; 7.5%) or tricuspid (n=658; 92,4%) anatomy. The overall mean age was 81±5.6 years. At baseline no significant differences were found between the 2 groups. BAV required more frequently both pre dilatation (94...
October 30, 2018: EuroIntervention
Adriano Caixeta, Carlos M Campos, Cordula Felix, Alaide Chieffo, Piera Capranzano, Hiroyoshi Kawamoto, Claudia Tamburino, Roberto Diletti, José de Ribamar Costa, Yoshinobu Onuma, Robert-Jan van Geuns, Antonio L Bartorelli, Antonio Colombo, Corrado Tamburino, Patrick W Serruys, Alexandre Abizaid
AIMS: To investigate the predictors of long-term adverse clinical events after implantation of the everolimus-eluting Absorb bioresorbable vascular scaffold (BVS). METHODS AND RESULTS: We pooled patient-level databases derived from the large-scale ABSORB EXTEND study and five high-volume international centers. Between November 2011 and November 2015, 1,933 patients underwent PCI with a total of 2,372 Absorb BVS implanted. The median age was 61.0 (IQR 53.0 to 68...
October 30, 2018: EuroIntervention
Osung Kwon, Pil Hyung Lee, Seung-Whan Lee, Jong-Young Lee, Do-Yoon Kang, Jung-Min Ahn, Duk-Woo Park, Soo-Jin Kang, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Seung-Jung Park
AIMS: We evaluated the contribution of the retrograde approach to real-world practice over time and its long-term outcomes in chronic total occlusion (CTO)-percutaneous coronary intervention (PCI). METHODS AND RESULTS: We evaluated 1,635 CTO procedures conducted at our high-volume center between 2003 and 2015. The retrograde approach has been actively adopted in practice since January 2007. The primary endpoint is target-vessel failure (TVF), a composite of cardiac death, target-vessel-related myocardial infarction, or target-vessel revascularization/re-occlusion...
October 30, 2018: EuroIntervention
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