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EuroIntervention

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https://www.readbyqxmd.com/read/28262625/is-quantitative-coronary-angiography-reliable-in-assessing-the-late-lumen-loss-of-the-everolimus-eluting-bioresorbable-polylactide-scaffold-in-comparison-with-the-cobalt-chromium-metallic-stent
#1
Yohei Sotomi, Yoshinobu Onuma, Yosuke Miyazaki, Taku Asano, Yuki Katagiri, Erhan Tenekecioglu, Hans Jonker, Jouke Dijkstra, Robbert J de Winter, Joanna J Wykrzykowska, Gregg W Stone, Jeffrey J Popma, Ken Kozuma, Kengo Tanabe, Patrick W Serruys, Takeshi Kimura
AIMS: Immediately after stent/scaffold implantation, quantitative coronary angiography (QCA) with respect to optical coherence tomography (OCT) more severely underestimates the lumen diameter (LD) in Absorb than in XIENCE. This OCT-QCA discrepancy has not been evaluated at long-term follow-up. The present study aimed to assess the accuracy of QCA with reference to OCT in Absorb as compared to XIENCE. METHODS AND RESULTS: We assessed 2-year QCA and OCT in the ABSORB Japan randomized trial (Absorb n=87, XIENCE n=44)...
March 7, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28262624/a-novel-four-dimensional-angiographic-approach-to-assess-dynamic-superficial-wall-stress-of-coronary-arteries-in-vivo-initial-experience-in-evaluating-vessel-sites-with-subsequent-plaque-rupture
#2
Xinlei Wu, Clemens von Birgelen, Takashi Muramatsu, Yingguang Li, Niels Ramsing Holm, Johan H C Reiber, Shengxian Tu
AIMS: Repetitive and fluctuating stress is one important biomechanical mechanism that underlies the rupture of atherosclerotic plaques. We developed a novel coronary angiography-based method for in vivo 4-dimensional analysis of dynamic superficial wall stress (SWS) in coronary plaques and applied it for the first time in two clinical cases to investigate the potential relationship between dynamic stress concentration at baseline and plaque rupture during acute coronary syndrome (ACS) several months later...
March 7, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28262623/second-generation-magnesium-scaffold-magmaris-device-design-and-preclinical-evaluation-in-a-porcine-coronary-artery-model
#3
Ron Waksman, Philine Zumstein, Martin Pritsch, Eric Wittchow, Michael Haude, Capucine Lapointe-Corriveau, Guy Leclerc, Michael Joner
AIMS: The second-generation drug-eluting absorbable magnesium scaffold Magmaris, recently introduced for treatment of obstructive coronary atherosclerotic lesions, suggests a good safety profile, but preclinical assessment is important for predicting clinical performance. METHODS AND RESULTS: Ninety Magmaris scaffolds were implanted into non-diseased porcine and rabbit models. A bioresorbable vascular scaffold (Absorb) and the permanent drugeluting stent (Xience Xpedition) served as controls...
March 7, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28262622/in-vivo-long-term-evaluation-of-the-novel-mitra-spacertm-technology-experimental-validation-in-the-ovine-model
#4
Athanasios Peppas, Ariel Furer, Jon Wilson, Geng-Hua Yi, Yanping Cheng, Karl Van Wygerden, Christopher Seguin, Masahiko Shibuya, Grzegorz L Kałuża, Juan F Granada
AIMS: The Mitra-SpacerTM (Cardiosolutions, Bridgewater, MA, USA) is designed to treat mitral regurgitation by introducing a dynamic spacer that constantly adapts to the changing hemodynamic conditions during the cardiac cycle. We aimed to evaluate the performance and safety of this device in the chronic ovine model. METHODS AND RESULTS: Eight (8) sheep were enrolled in this study. Through a left thoracotomy, the Mitra-SpacerTM was inserted via trans-apical approach and advanced in to the left atrium (LA) under imaging guidance...
March 7, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28246061/five-year-follow-up-of-underexpanded-and-overexpanded-bioresorbable-scaffolds-self-correction-and-impact-on-shear-stress
#5
Ryo Torii, Erhan Tenekecioglu, Christos Bourantas, Eric Poon, Vikas Thondapu, Frank Gijsen, Yohei Sotomi, Yoshinobu Onuma, Peter Barlis, Andrew S H Ooi, Patrick W Serruys
No abstract text is available yet for this article.
March 2, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28246060/predilation-sizing-and-post-dilation-scoring-in-patients-undergoing-everolimus-eluting-bioresorbable-scaffold-implantation-for-prediction-of-cardiac-adverse-events-development-and-internal-validation-of-the-psp-score
#6
Luis Ortega-Paz, Davide Capodanno, Tommaso Gori, Holger Nef, Azeem Latib, Giuseppe Caramanno, Carlo Di Mario, Christoph Naber, Maciej Lesiak, Piera Capranzano, Jens Wiebe, Julinda Mehilli, Aleksander Araszkiewicz, Stelios Pyxaras, Alessio Mattesini, Salvatore Geraci, Toru Naganuma, Antonio Colombo, Thomas Münzel, Manel Sabaté, Corrado Tamburino, Salvatore Brugaletta
AIMS: The aim of the study was to develop a scoring model to evaluate the quality of bioresorbable vascular scaffold (BVS) implantation and determine the model's usefulness in predicting adverse cardiac events. METHODS AND RESULTS: The implantation technique and clinical outcomes of 1,736 lesions treated with BVS were analysed using the GHOST-EU registry. Predilation, scaffold sizing, and post-dilation (PSP) were scored according to the hazard model derived from the weight of these variables...
March 2, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28246059/dmax-for-sizing-psp-1-psp-2-psp-3-or-oct-guidance-interventionalist-s-jargon-or-indispensable-implantation-techniques-for-short-and-long-term-outcomes-of-absorb-brs
#7
Patrick W Serruys, Yoshinobu Onuma
No abstract text is available yet for this article.
March 2, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28242589/intravenous-beta-blocker-therapy-in-st-segment-elevation-myocardial-infarction-treated-with-primary-percutaneous-coronary-intervention-is-not-associated-with-benefit-regarding-short-term-mortality-a-swedish-nationwide-observational-study
#8
Moman A Mohammad, Pontus Andell, Sasha Koul, Liyew Desta, Tomas Jernberg, Elmir Omerovic, Jonas Spaak, Ole Fröbert, Jens Jensen, Thomas Engstrøm, Claes Hofman-Bang, Hans Persson, David Erlinge
AIMS: To investigate the impact of intravenous (IV) beta-blocker therapy on short-term mortality and other in-hospital events in patients with ST-segment elevation myocardial infarction (STEMI) treated with dual antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PCI). METHODS AND RESULTS: Using the nationwide Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) registry, we identified all patients with STEMI undergoing PCI between 2006 and 2013...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28242588/effects-of-successful-percutaneous-coronary-intervention-of-chronic-total-occlusions-on-myocardial-perfusion-and-left-ventricular-function
#9
Wijnand J Stuijfzand, P Stefan Biesbroek, Pieter G Raijmakers, Roel S Driessen, Stefan P Schumacher, Pepijn van Diemen, Jeffrey van den Berg, Robin Nijveldt, Adriaan A Lammertsma, Simon J Walsh, Colm G Hanratty, James C Spratt, Albert C van Rossum, Alexander Nap, Niels van Royen, Paul Knaapen
AIMS: The aim of the present study was to investigate the effects of successful PCI CTO on absolute myocardial blood flow (MBF) and functional recovery. METHODS AND RESULTS: Patients with a documented CTO were prospectively examined for ischemia and viability with H215O positron emission tomography (PET) and late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR). Sixty-nine consecutive patients, in whom PCI was successful, underwent follow-up PET and CMR after approximately 12 weeks to evaluate potential improvement of MBF as well as systolic function...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28242587/impact-of-crossing-strategy-on-mid-term-outcomes-following-percutaneous-revascularisation-of-coronary-chronic-total-occlusions
#10
Lorenzo Azzalini, Rustem Dautov, Emmanouil S Brilakis, Soledad Ojeda, Susanna Benincasa, Barbara Bellini, Aris Karatasakis, Jorge Chavarría, Bavana V Rangan, Manuel Pan, Mauro Carlino, Antonio Colombo, Stéphane Rinfret
AIMS: To compare the impact of crossing strategies on mid-term outcomes following chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS AND RESULTS: We compiled a multicentre registry of consecutive patients undergoing successful CTO PCI. Patients were divided in three groups: true-to-true (TTT) approach, modern dissection/re-entry (DR) techniques (CrossBoss/Stingray, reverse CART), and old DR techniques (LAST, STAR, CART). Cox regression was used to identify independent predictors of major adverse cardiac events (MACE: cardiac death, myocardial infarction and target-vessel revascularisation)...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28242586/feasibility-and-safety-of-direct-catheter-based-thrombectomy-in-the-treatment-of-acute-ischemic-stroke-cooperation-of-cardiologists-neurologists-and-radiologists-prospective-registry-prague-16
#11
Petr Widimsky, Boris Koznar, Tomas Peisker, Peter Vasko, Filip Rohac, Jana Vavrova, Josef Kroupa, Ivana Stetkarova
AIMS: The aim of this study was to evaluate the role of direct catheter-based thrombectomy (d-CBT, without thrombolysis) and the feasibility and safety of d-CBT performed in an interventional cardiology center. METHODS AND PATIENTS: Single center, prospective observational registry based on the prespecified protocol included 3 months follow-up. The decision to perform acute stroke intervention was done by a neurologist based on the clinical and imaging findings...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28242585/at-least-7-days-delayed-stenting-using-minimalist-immediate-mechanical-intervention-mimi-in-st-segment-elevation-myocardial-infarction-the-super-mimi-study
#12
Petru Mester, Helene Bouvaist, Nicolas Delarche, Frédéric Bouisset, Mohamed Abdellaoui, Pierre-Yves Petiteau, Olivier Dubreuil, Ziad Boueri, Mohamed Chettibi, Géraud Souteyrand, Hend Madiot, Loic Belle
AIMS: To ascertain whether a minimalist immediate mechanical intervention (MIMI) aiming to restore an optimal Thrombolysis In Myocardial Infarction (TIMI) flow in the culprit artery, followed ≥7 days later by a second percutaneous coronary intervention with intentional stenting is safe in patients with ST- segment elevation myocardial infarction and large thrombotic burden. METHODS AND RESULTS: SUPER-MIMI was a prospective, observational trial conducted between January 2014 and April 2015 in 14 French centres...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28242584/impact-of-stent-overlapping-on-long-term-clinical-outcomes-in-patients-with-st-segment-elevation-myocardial-infarction-insights-from-the-5-year-follow-up-of-the-examination-trial
#13
Luis Ortega-Paz, Salvatore Brugaletta, Giuseppe Giacchi, Kohki Ishida, Angel Cequier, Andrés Iñiguez, Antonio Serra, Pilar Jiménez-Quevedo, Vicente Mainar, Gianluca Campo, Maurizio Tespili, Peter den Heijer, Marco Valgimigli, Patrick W Serruys, Manel Sabaté
AIMS: To compare long-term outcomes of STEMI patients treated with overlap vs. no-overlap stents. METHODS AND RESULTS: We analyzed the 1 and 5-year clinical outcomes of 1498 STEMI patients according to overlap stent implantation. The primary endpoint was a patient-oriented composite endpoint (PoCE) of all-cause death, myocardial infarction, and repeated revascularization. Stent thrombosis data was also analyzed. Four hundred four (27.0%) patients were treated with overlapping stents, whereas the remaining 1094 (73...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28242583/clinical-implications-of-the-residual-syntax-score-after-percutaneous-coronary-intervention-in-patients-with-chronic-total-occlusion-and-multi-vessel-coronary-artery-disease-a-comparison-with-coronary-artery-bypass-grafting
#14
Woo Jin Jang, Jeong Hoon Yang, Young Bin Song, Joo-Yong Hahn, Jin-Ho Choi, Woo Jung Chun, Ju Hyeon Oh, Yong Hwan Park, Wook Sung Kim, Young Tak Lee, Hyeon-Cheol Gwon, Seung-Hyuk Choi
AIMS: We evaluated clinical impact of residual SYNTAX score (rSS) after percutaneous coronary intervention (PCI) in patients with chronic total occlusion (CTO) and multi-vessel coronary artery disease (CAD). METHODS AND RESULTS: We analyzed data from 1,043 patients with CTO and multi-vessel CAD who were treated with PCI or coronary artery bypass grafting (CABG). Patients were divided into three groups: patients with rSS≤12 after PCI (rSS≤12 group, n=445), patients with rSS>12 after PCI (rSS>12 group, n=150), and patients who underwent CABG (CABG group, n=448)...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28218606/microvascular-dysfunction-following-st-elevation-myocardial-infarction-and-its-recovery-over-time-is-associated-with-short-and-long-term-cardiac-function
#15
Mariëlla E C J Hassell, Matthijs Bax, Martijn A van Lavieren, Robin Nijveldt, Alexander Hirsch, Lourens Robbers, Koen M Marques, Jan G P Tijssen, Felix Zijlstra, Albert C van Rossum, Ronak Delewi, Jan J Piek
AIMS: It is unclear whether microvascular dysfunction following ST-elevation myocardial infarction (STEMI) is prognostic for long-term left ventricular function (LVF). and whether recovery of the microvasculature status is associated with LVF improvement. METHODS AND RESULTS: In 62 patients, Coronary Flow Reserve (CFR) and Hyperemic Microvascular Resistance Index (HMRI) in the infarct related artery (IRA) was assessed by intracoronary Doppler flow measurements within 1 week and at 4 months...
February 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28218605/comparison-of-a-new-slender-6-french-sheath-with-a-standard-5-french-sheath-for-transradial-coronary-angiography-and-intervention-a-randomized-multicenter-trial-the-rap-and-beat-radial-artery-patency-and-bleeding-efficacy-adverse-event-trial
#16
Adel Aminian, Shigeru Saito, Akihiko Takahashi, Ivo Bernat, Robert Lee Jobe, Takashi Kajiya, Ian C Gilchrist, Yves Louvard, Ferdinand Kiemeneij, Niels Van Royen, Seiji Yamazaki, Takashi Matsukage, Sunil V Rao
AIMS: The 6 French(Fr) Glidesheath Slender (GSS6Fr, Terumo, Japan) is a recently developed thin-walled radial sheath with an outer diameter (OD) that is smaller than the OD of standard 6Fr sheaths. The effect of this introducer sheath on radial artery occlusion (RAO) is unknown. METHODS AND RESULTS: We conducted a randomized, multicenter, non-inferiority trial comparing the GSS6Fr against the standard 5Fr Glidesheath (GS5Fr, Terumo, Japan) in patients undergoing TR coronary angiography and/or intervention...
February 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28218604/everolimus-eluting-bioresorbable-vascular-scaffold-for-treatment-of-complex-chronic-total-occlusions
#17
Jiang Ming Fam, Soledad Ojeda, Roberto Garbo, Azeem Latib, Alessio La Manna, Beatriz Vaquerizo, Marouane Boukhris, Georgios J Vlachojannis, Robert Jan van Geuns, Babu Ezhumalai, Hiroyoshi Kawamoto, Jors van der Sijde, Cordula Felix, Manuel Pan, Roberta Serdoz, Giacomo Giovanni Boccuzzi, Marcella De Paolis, Gennaro Sardella, Corrado Tamburino, Pieter C Smits, Carlo Di Mario, Ashok Seth, Antonio Serra, Antonio Colombo, Patrick Serruys, Alfredo R Galassi, Felix Zijlstra, Nicolas M van Mieghem, Roberto Diletti
AIMS: Bioresorbable vascular scaffolds (BVS) represent a novel therapeutic option for the treatment of coronary artery diseases. The objective of this study is to evaluate the feasibility of BVS implantation in complex chronic total occlusions (CTO). METHODS AND RESULTS: The present report is a multi-centre registry evaluating results after BVS deployment in challenging CTO lesions defined as J-CTO score≥2 (difficult or very difficult). A total of 105 patients were included in the present analysis...
February 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28218603/frequency-and-clinical-course-of-cerebral-embolism-in-patients-undergoing-transcatheter-left-atrial-appendage-closure
#18
Nicolas Majunke, Franziska Eplinius, Matthias Gutberlet, Sven Moebius-Winkler, Ingo Daehnert, Matthias Grothoff, Stephan Schürer, Norman Mangner, Philipp Lurz, Sandra Erbs, Katharina Kirsch, Gerhard Schuler, Marcus Sandri
AIMS: To assess silent and clinically apparent cerebral embolic events in patients undergoing transcatheter left atrial appendage closure. METHODS AND RESULTS: In this prospective single-center study 28 patients underwent percutaneous closure of the left atrial appendage. In all patients a diffusion-weighted magnetic resonance imaging (DWI-MRI) study was performed before, the day after the procedure and during routine follow-up after 45 days. All patients underwent neurological assessment at the time of DWI-MRI...
February 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28191876/clinical-and-angiographic-predictors-of-hemodynamically-significant-angiographic-lesions-development-and-validation-of-a-risk-score-to-predict-positive-fractional-flow-reserve
#19
Nishtha Sareen, Usman Baber, Safwan Kezbor, Sonny Sayseng, Melissa Aquino, Roxana Mehran, Joseph Sweeny, Nitin Barman, Annapoorna Kini, Samin K Sharma
AIMS: Coronary revascularization based upon physiological evaluation of lesions improves clinical outcomes. Angiographic or visual stenosis assessment alone is insufficient in predicting hemodynamic stenosis severity by Fractional Flow reserve (FFR) and therefore cannot be used to guide revascularization, particularly in the lesion subset (<70%). Accordingly, we sought to identify independent determinants of angiographic intermediate lesions with hemodynamic significance. METHODS AND RESULTS: We assessed consecutive intermediate lesions for patients from January 2014-April 2015 at our institution...
February 14, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28191875/clinical-outcomes-with-the-stentys-self-apposing-coronary-stent-in-patients-presenting-with-st-segment-elevation-myocardial-infarction-2-year-insights-from-the-appostion-iii-a-post-market-registry-to-assess-the-stentys-self-expanding-coronary-stent-in-acute
#20
Huangling Lu, Maik J Grundeken, Nicola S Vos, Alexander J J Ijsselmuiden, Robert-Jan van Geuns, Rainer Wessely, Thomas Dengler, Alessio La Manna, Johanne Silvain, Gilles Montalescot, René Spaargaren, Jan G P Tijssen, Giovanni Amoroso, Robbert J de Winter, Karel T Koch
AIMS: The APPOSITION III registry evaluated the feasibility and performance of the STENTYS self- apposing stent in a ST-segment elevation myocardial infarction (STEMI) population. This novel self- apposing stent device lowers stent strut malapposition rates and therefore bears the potential to prevent stent undersizing during primary percutaneous coronary intervention (PCI) in STEMI patients. Up to date, no long-term data is available using this device in the setting of STEMI. We aimed to evaluate long-term clinical outcomes of the APPOSITION III registry...
February 14, 2017: EuroIntervention
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