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https://www.readbyqxmd.com/read/29769168/pressure-wire-compared-to-microcatheter-sensing-for-coronary-fractional-flow-reserve-the-perform-study
#1
Ziad A Ali, Yasir Parviz, Matthew Brinkman, Mitsuaki Matsumura, Björn Redfors, David A Brogno, Maria D Corral, Khady N Fall, Gary S Mintz, Gregg W Stone, Akiko Maehara, Allen Jeremias, Ajay J Kirtane
AIMS: Among technologies used to assess FFR, a monorail, sensor-tipped micro pressure catheter (PC) may be advantageous for delivery and re-assessment. We sought to determine whether the larger cross-sectional area of the PC influences FFR measurements compared to the pressure wire. METHODS AND RESULTS: PERFORM was a single-center, prospective study designed to determine the precision and accuracy of the PC compared with the pressure wire (PW) for measurement of FFR...
May 15, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29769167/impact-of-sex-on-comparative-outcomes-of-bivalirudin-versus-unfractionated-heparin-in-patients-with-acute-coronary-syndromes-undergoing-invasive-management-a-pre-specified-analysis-of-the-matrix-trial
#2
Giuseppe Gargiulo, Bruno R da Costa, Enrico Frigoli, Cataldo Palmieri, Marco Stefano Nazzaro, Camillo Falcone, Armando Liso, Carlo Vigna, Fabio Abate, Marco Comeglio, Roberto Diletti, Gabriele Gabrielli, Emilio Di Lorenzo, Pietro Mazzarotto, Marco Zimarino, Claudio Moretti, Antonio Colombo, Carlo Penzo, Giampaolo Pasquetto, Salvatore Brugaletta, Fabio Ferrari, Gavino Casu, Vincenzo Guiducci, Antonio Dellavalle, Francesco Liistro, Ciro Mauro, Arnoud W J Van't Hof, Elmir Omerovic, Salvatore Curello, Jose Maria de la Torre Hernandez, Stefano De Servi, Flavia Belloni, Stephan Windecker, Marco Valgimigli
AIMS: To assess whether bivalirudin compared with unfractionated heparin (UFH) is associated with consistent outcomes in male and female patients with acute coronary syndrome (ACS) undergoing invasive management. METHODS AND RESULTS: In the MATRIX program,7213 patients were randomized to bivalirudin or UFH.Patients in bivalirudin group were subsequently assigned to receive or not to receive a post-PCI infusion.The 30-day coprimary outcomes were major adverse cardiovascular and cerebrovascular events (MACE),defined as death,myocardial infarction,or stroke,and net adverse clinical events (NACE),defined as MACE or major bleeding...
May 15, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29769166/coronary-lesion-progression-as-assessed-by-fractional-flow-reserve-ffr-and-angiography
#3
Panagiotis Xaplanteris, Argyris Ntalianis, Bernard De Bruyne, Teresa Strisciuglio, Mariano Pellicano, Giovanni Ciccarelli, Anastasios Milkas, Emanuele Barbato
AIMS: To explore the evolution of coronary lesions that had repeated physiologic evaluation by FFR as an endpoint, describe the clinical significance of longitudinal FFR change (ΔFFR = FFR follow-up - FFR baseline), its correlation with angiographic indices and identify predictors of FFR follow-up. METHODS AND RESULTS: A retrospective, single-center analysis of 414 stenoses (331 patients) with consecutive FFR measurements at least six months apart was performed [median time interval: 24 (17, 37) months]...
May 15, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29769165/radial-hemostasis-is-facilitated-with-a-potassium-ferrate-hemostatic-patch-the-statseal-with-tr-band-assessment-trial-stat
#4
Arnold H Seto, William Rollefson, Mitul P Patel, William M Suh, David M Tehrani, Jacqueline A Nguyen, Daniel G Amador, Omid Behnamfar, Vinisha Garg, Mauricio G Cohen
AIMS: Hemostasis is a limiting factor for discharge after uncomplicated transradial procedures. The potassium ferrate hemostatic patch (PFHP) may serve as an adjunct to the air-bladder TR band (TRB) and allow expedited deflation of the TRB. METHODS AND RESULTS: Prospective multicenter randomized controlled trial comparing radial hemostatic protocols. Deflation of the TRB was attempted at 40 minutes with PFHP and at 120 minutes without the PFHP. The primary outcome was time to full deflation of the TRB with hemostasis...
May 15, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29769164/the-effectiveness-of-excimer-laser-angioplasty-to-treat-coronary-in-stent-restenosis-with-peri-stent-calcium-as-assessed-by-optical-coherence-tomography
#5
Tetsumin Lee, Richard A Shlofmitz, Lei Song, Theofanis Tsiamtsiouris, Thomas Pappas, Antonio Madrid, Allen Jeremias, Elizabeth S Haag, Ziad A Ali, Jeffery W Moses, Mitsuaki Matsumura, Gary S Mintz, Akiko Maehara
AIMS: We evaluated the effectiveness of excimer laser coronary angioplasty (ELCA) to treat in-stent restenosis (ISR) due to peri-stent calcium-related stent under-expansion as assessed by optical coherence tomography (OCT). METHODS AND RESULTS: We studied 81 patients (81 lesions with ISR, stent under-expansion, and peri-stent calcium >90°) who underwent OCT imaging both pre- and post-percutaneous coronary intervention and compared lesions treated with ELCA (n=23) vs without ELCA (n=58)...
May 15, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741489/initial-result-of-angioscopy-guided-wire-crossing-technique-under-continuous-saline-infusion-for-chronic-total-occlusion-in-femoropopliteal-disease
#6
Masamichi Yano, Keisuke Yasumura, Koji Yasumoto, Akihiro Tanaka, Naoki Mori, Daisuke Nakamura, Yasuyuki Egami, Ryu Shutta, Jun Tanouchi, Masami Nishino
AIMS: We occasionally experience endovascular therapy (EVT) failure as a consequence of wire-crossing into the subintima for chronic total occlusion (CTO) in peripheral arteries. Although several reports have demonstrated the importance of accurate wire-crossing into the ostial site of the CTO true lumen to succeed, it is difficult to visualize the CTO ostium before wiring using angiography or intravascular ultrasonography (IVUS). Thus, we directly visualize the ostial sites of lesions and wire manipulation during EVT by angioscopy and evaluate the efficacy and safety of angioscopy-guided EVT under continuous infusion of saline (AGECIS) in peripheral arteries...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741488/long-term-durability-and-hemodynamic-performance-of-a-self-expanding-transcatheter-heart-valve-beyond-5-years-after-implantation-a-prospective-observational-study-applying-the-standardized-definitions-of-structural-deterioration-and-valve-failure
#7
Erik W Holy, Julia Kebernik, Mohammad Abdelghani, Simon F Stämpfli, Jens Hellermann, Abdelhakim Allali, Mohamed El-Mawardy, Susanne Sachse, Thomas F Lüscher, Felix C Tanner, Gert Richardt, Mohamed Abdel-Wahab
AIMS: Long-term results of transcatheter aortic valve implantation (TAVI), in particular the incidence of bioprosthetic valve failure (BVF), are uncertain. METHODS AND RESULTS: The study prospectively included all 152 patients who had undergone TAVI with the self-expanding CoreValve™ up to December 2011 at the Heart Center, Bad Segeberg, Germany. Late BVF (>30 days) was defined as either: 1) Severe structural valve deterioration (trans-prosthetic mean pressure gradient ≥40 mmHg and/or ≥20 mmHg rise from baseline OR severe intra-prosthetic aortic regurgitation), OR 2) Bioprosthetic valve dysfunction leading to death or re-intervention...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741487/regular-drug-eluting-stents-versus-dedicated-bifurcation-drug-eluting-bioss%C3%A2-stents-for-coronary-bifurcation-treatment-four-year-results-of-randomized-polbos-i-and-polbos-ii-clinical-trials
#8
Robert J Gil, Jacek Bil, Adam Kern, Luis A Ingio Garcia, Radoslaw Formuszewicz, Slawomir Dobrzycki, Dobrin Vassilev, Agnieszka Segiet
AIMS: The aim of this study was to analyze 4-year follow-up data of two clinical trials POLBOS I & II to compare regular DES (rDES) and dedicated bifurcation stents BiOSS®. METHODS AND RESULTS: In POLBOS trials BiOSS® stents were compared with rDES in patients with stable CAD or NSTE-ACS (POLBOS I: paclitaxel eluting BiOSS® Expert vs rDES; POLBOS II: sirolimus eluting BiOSS® LIM vs rDES). 445 patients with 222 patients in BiOSS group and 223 patients in rDES group were analyzed...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741486/computed-tomography-based-oversizing-and-incidence-of-para-valvular-aortic-regurgitation-and-permanent-pacemaker-implantation-with-a-new-generation-self-expanding-transcatheter-heart-valve
#9
Ung Kim, Philipp Blanke, Stephan Windecker, Albert M Kasel, Ulrich Schäfer, Darren Walters, Axel Linke, Herve Le Breton, Gerhard Schymik, Mark S Spence, Lars Sondergaard, Mohammed Abdel-Wahab, Stephen Worthley, Didier Tchetche, Hermann Reichenspurner, Mickael Ohana, Stephanie L Sellers, Jonathon A Leipsic
AIMS: We aimed to evaluate the relationship between CT-based annular perimeter oversizing and the incidence of paravalvular aortic regurgitation (PAR) and permanent pacemaker (PPM) implantation in patients treated with the new self-expanding CENTERA transcatheter heart valve (THV) for severe aortic stenosis. METHODS AND RESULTS: 198 patients in the CENTERA-EU trial were stratified priori into four groups based on the perimeter oversizing (2.5%-10%, 10-15%, 15-20% and >20%)...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741485/one-year-results-of-transcatheter-treatment-of-severe-tricuspid-regurgitation-using-the-edge-to-edge-repair-technique
#10
Daniel Braun, Michael Nabauer, Mathias Orban, Andrea Englmaier, Diana Rösler, Christian Hagl, Steffen Massberg, Jörg Hausleiter
AIMS: The aim of this study was to evaluate one-year durability and clinical outcome of transcatheter tricuspid valve repair using the edge-to-edge repair technique in symptomatic patients with severe tricuspid regurgitation (TR). METHODS AND RESULTS: We evaluated twenty-four consecutive patients suffering from severe right sided heart failure (NYHA III-IV) primarily due to moderate to severe primary tricuspid regurgitation. Applying a modified steering technique for clip delivery, 8 patients were treated for isolated severe TR, while 16 patients were treated for moderate to severe TR and concomitant severe mitral regurgitation...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741484/comparison-of-acute-thrombogenicity-for-magnesium-versus-stainless-steel-stents-in-a-porcine-arteriovenous-shunt-model
#11
Michael J Lipinski, Eduardo Acampado, Qi Cheng, Lila Adams, Sho Torii, Jiaxiang Gai, Rebecca Torguson, David G Hellinga, Michael Joner, Claus Harder, Philine Zumstein, Aloke V Finn, Frank D Kolodgie, Renu Virmani, Ron Waksman
Aims The aetiology for reduced thrombogenicity of the Magmaris resorbable magnesium scaffold (RMS) when compared with the Absorb bioresorbable vascular scaffold remains unclear. We therefore investigated whether the Magmaris RMS has platelet-repelling properties by comparing its acute thrombogenicity with an equivalent stainless steel stent in an arteriovenous shunt model. Methods and Results An ex vivo porcine carotid jugular arteriovenous shunt was established and connected to Sylgard tubing containing the Magmaris RMS with sirolimus-eluting PLLA coating and an equivalent 316L stainless steel stent with sirolimus-eluting PLLA coating...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741483/incidence-of-procedural-myocardial-infarction-and-cardiac-magnetic-resonance-imaging-detected-myocardial-injury-following-percutaneous-coronary-intervention-with-rotational-atherectomy
#12
Margaret McEntegart, David Corcoran, David Carrick, Guillaume Clerfond, Novalia Sidik, Damien Collison, Keith R Robertson, Aadil Shaukat, Stuart Watkins, Paul R Rocchicholi, Hany Eteiba, Mark P Petrie, Mitchell M Lindsay, Keith G Oldroyd, Colin Berry
No abstract text is available yet for this article.
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741482/mortality-risk-after-transcatheter-aortic-valve-implantation-analysis-of-the-predictive-accuracy-of-the-transcatheter-valve-therapy-registry-risk-assessment-model
#13
Pablo Codner, Waqas Malick, Remi Kouz, Amisha Patel, Cheng-Han Chen, Juan Terre, Uri Landes, Torsten Peter Vahl, Isaac George, Tamim Nazif, Ajay J Kirtane, Omar K Khalique, Rebecca T Hahn, Martin B Leon, Susheel Kodali
AIMS: Risk assessment tools currently used to predict mortality in transcatheter aortic valve implantation (TAVI) were designed for patients undergoing cardiac surgery. We aim to assess the accuracy of the TAVI dedicated American College of Cardiology / Transcatheter Valve Therapies (ACC/TVT) risk score in predicting mortality outcomes. METHODS AND RESULTS: Consecutive patients (n=1038) undergoing TAVI at a single institution from 2014 to 2016 were included. The ACC/TVT registry mortality risk score, the Society of Thoracic Surgeons - Patient Reported Outcomes (STS-PROM) score and the EuroSCORE II were calculated for all patients...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741481/urgent-balloon-aortic-valvuloplasty-in-patients-with-cardiogenic-shock-related-to-severe-aortic-stenosis-time-matters
#14
Nicolas Debry, Patrick Kone, Flavien Vincent, Gilles Lemesle, Cédric Delhaye, Guillaume Schurtz, Hugues Spillemaeker, Sina Porouchani, Augustin Coisne, Jean-Luc Auffray, Arnaud Sudre, Nicolas Lamblin, Laurent Bonello, Eric Van Belle
AIMS: To assess outcomes of balloon aortic valvuloplasty (BAV) as a rescue therapy in patients with cardiogenic shock (CS) related to severe aortic stenosis (AS). METHODS AND RESULTS: Forty-four consecutive patients, n=31 with hypotensive-CS (HCS) and n=13 with non-hypotensive CS (NHCS) due to acutely decompensated severe AS, from two centres were treated with emergency BAV. Composite primary endpoint was mortality or recurrent CS at 1-year follow-up. These patients (77...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29701178/fourier-to-odyssey-the-end-of-the-journey-for-lipid-lowering-therapy-trials-lessons-from-recent-clinical-trials-with-anti-pcsk9-antibodies
#15
Pierre Sabouret, Denis Angoulvant, Atul Pathak
No abstract text is available yet for this article.
April 27, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29688182/intravascular-ultrasound-in-the-evaluation-and-treatment-of-left-main-coronary-artery-disease-a-consensus-statement-from-the-european-bifurcation-club-ebc
#16
Gary S Mintz, Thierry Lefèvre, Jens Lassen, Luca Testa, Manuel Pan, Jag Singh, Goran Stankovic, Adrian P Banning
No abstract text is available yet for this article.
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29688181/saline-induced-pd-pa-ratio-predicts-functional-significance-of-coronary-stenosis-assessed-using-fractional-flow-reserve
#17
Yoshiharu Fujimori, Tomoko Baba, Kyohei Yamazaki, Satoshi Hashimoto, Yasushi Yamanaka, Kenichiro Ebisuda, Kazuto Kurihara, Naoki Koike, Nao Takeuchi, Shigeru Nishiyama, Yuya Terasawa, Tadamasa Wakabayashi, Taku Imai
AIMS: Fractional flow reserve (FFR), assessed using distal coronary pressure/aortic pressure (Pd)/(Pa) ratio, functionally evaluates coronary stenosis. An assessment method without vasodilators would be helpful. A single intracoronary bolus of saline decreases Pd because of the speculated low-viscosity effect. We hypothesized that saline-induced Pd/Pa ratio (SPR) could functionally evaluate coronary stenosis. This study aimed to test the accuracy and utility of SPR for predicting FFR ≤0...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29688180/patient-selection-echocardiographic-screening-and-treatment-strategies-for-interventional-tricuspid-repair-using-the-edge-to-edge-repair-technique
#18
Jörg Hausleiter, Daniel Braun, Mathias Orban, Azeem Latib, Philipp Lurz, Peter Boekstegers, Ralph Stephan von Bardeleben, Marek Kowalski, Rebecca T Hahn, Francesco Maisano, Christian Hagl, Steffen Massberg, Michael Nabauer
Severe tricuspid regurgitation (TR) has long been neglected despite its well known association with mortality. While surgical mortality rates remain high in isolated tricuspid valve surgery, interventional TR repair is rapidly evolving as an alternative to cardiac surgery in selected patients at high surgical risk. Currently, interventional edge-to-edge repair is the most frequently applied technique for TR repair even though the device has not been developed for this particular indication. Due to the inherent differences in tricuspid and mitral valve anatomy and pathology, percutaneous repair of the tricuspid valve is challenging due to a variety of factors including the complexity and variability of tricuspid valve anatomy, echocardiographic visibility of the valve leaflets, and device steering to the tricuspid valve...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29688179/comprehensive-physiological-evaluation-of-epicardial-and-microvascular-coronary-domains-using-vascular-conductance-and-zero-flow-pressure
#19
Nina W van der Hoeven, Guus A de Waard, Alicia Quirós, Alfonso De Hoyos, Christopher Broyd, Sukhjinder S Nijjer, Tim P van de Hoef, Ricardo Petraco, Roel S Driessen, Hernán Mejía-Rentería, Yuetsu Kikuta, Mauro Echavarría Pinto, Peter M van de Ven, Martijn Meuwissen, Paul Knaapen, Jan J Piek, Justin E Davies, Niels van Royen, Javier Escaned
AIMS: Assessment of the coronary circulation has largely been based on pressure ratios (epicardial-) and resistance (micro-vessels). Simultaneous assessment of epicardial- (CEPI) and microvascular conductance (CMICRO) provides an intuitive approach using the same units for both compartments and expressing the actual deliverability of blood. The aim of study was to develop a novel integral method to assessing the functional severity of epicardial and microvascular disease. METHODS AND RESULTS: We performed intracoronary Doppler and pressure in 403 vessels in 261 stable patients...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29688178/coronary-sinus-reducer-implantation-improves-symptoms-ischemia-and-physical-capacity-in-patients-with-refractory-angina-unsuitable-for-myocardial-revascularization-a-single-center-experience
#20
Maayan Konigstein, Samuel Bazan, Miri Revivo, Shmuel Banai
AIMS: To evaluate the clinical efficacy of the Coronary Sinus Reducer implantation in alleviating angina symptoms and improving objective ischemia parameters and indices of physical capacity Methods and results: Patient with refractory angina (CCS class 3-4) were treated with the Reducer. Baseline, and follow-up evaluation consisted of clinical assessment including completion of Seattle angina Questionnaire (SAQ) and CCS class evaluation, and objective assessment by treadmill exercise test, Dobutamine echocardiography and 6-minute walk test (6MWT)...
April 24, 2018: EuroIntervention
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