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EuroIntervention

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https://www.readbyqxmd.com/read/29313819/real-world-safety-and-efficacy-of-watchman-laa-closure-at-one-year-in-patients-on-dual-antiplatelet-therapy-results-of-the-dapt-subgroup-from-the-ewolution-all-comers-study
#1
Martin W Bergmann, Hüseyin Ince, Stephan Kische, Thomas Schmitz, Felix Meincke, Boris Schmidt, David Foley, Timothy R Betts, Marek Grygier, Alexey V Protopopov, Kenneth M Stein, Lucas V A Boersma
AIMS: The study aims to confirm efficacy and safety of WATCHMAN LAA closure in AF patients unsuitable for oral anticoagulation. METHODS AND RESULTS: The EWOLUTION registry prospectively collects all clinical data on 1005 European patients implanted with a WATCHMAN device. Following the procedure, 605 patients (60.2%) received dual antiplatelet therapy according to the local standard; DAPT was discontinued in 85% of pts within 1 year. CHA2DS2-VASc and HAS-BLED scores were 4...
January 9, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29313818/long-term-mortality-in-patients-with-severe-secondary-mitral-regurgitation-and-normal-left-ventricular-ejection-fraction-interventional-perspective
#2
Amr F Barakat, Mohammad Q Raza, Kinjal Banerjee, Rayji S Tsutsui, Amgad Mentias, Karim Abdur Rehman, Badal Thakkar, Sajjad Gul, Raquib Faruqui, Amar Krishnaswamy, Leonardo L Rodriguez, Richard Grimm, Brian Griffin, Emin Murat Tuzcu, Samir R Kapadia
AIMS: Patients with severe secondary mitral regurgitation (MR) and normal ejection fraction are being excluded from clinical trials evaluating transcatheter mitral devices. We sought to evaluate the long-term mortality with medical management alone in this patient population. METHODS AND RESULTS: We retrospectively evaluated patients diagnosed with ≥3+ mitral MR at our institution over 15 years. Only patients with ejection fraction ≥ 60% were included in the study...
January 9, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29313817/prediabetes-and-its-impact-on-clinical-outcome-after-coronary-intervention-in-a-broad-patient-population
#3
Marlies M Kok, Clemens von Birgelen, Naveed Sattar, Paolo Zocca, Marije M Löwik, Peter W Danse, Carl E Schotborgh, Martijn Scholte, Marc Hartmann, Gert D Kant, Cees Doelman, Melvyn Tjon Joe Gin, Martin G Stoel, Gert van Houwelingen, Gerard C M Linssen, Maarten J IJzerman, Carine J M Doggen, Liefke C van der Heijden
AIMS: It is unclear whether detection of prediabetes(Pre-DM) by routine assessment of glycated haemoglobin A1c(HbA1c) and fasting plasma glucose(FPG) among patients undergoing percutaneous coronary intervention(PCI) with contemporary drug-eluting stents(DES) may help identify subjects with increased event risk. We assessed the relation between glycaemia status and 1-year outcome after PCI. METHODS AND RESULTS: Glycaemia status was determined in 2,362 non-diabetic BIO-RESORT participants, treated at all four study sites, to identify Pre-DM (HbA1c 42-47mmol/mol; FPG 6...
January 9, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29278354/long-term-clinical-outcomes-of-a-crystalline-sirolimus-eluting-coronary-stent-with-a-fully-bioabsorbable-polymer-coating-five-year-outcomes-from-the-dessolve-i-and-ii-trials
#4
William Wijns, Mathias Vrolix, Stefan Verheye, Danny Schoors, Ton Slagboom, Marcel Gosselink, Edouard Benit, David Kandzari, Dennis Donohoe, John A Ormiston
AIMS: The aim was to evaluate the five-year clinical results of a sirolimus-eluting stent (MiStent SES) with a bioabsorbable coating designed for sustained drug delivery during and after rapid polymer dissolution. METHODS AND RESULTS: The five-year results from the DESSOLVE I and II trials including major adverse cardiac events (MACE), target lesion failure (TLF), target vessel failure (TVF), and stent thrombosis (ST) at five-year follow-up are reported. In DESSOLVE I, 10...
December 26, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29278353/long-term-safety-of-bioresorbable-scaffolds-insights-from-a-network-meta-analysis-including-91-trials
#5
Si-Hyuck Kang, Bill D Gogas, Ki-Hyun Jeon, Jie-Suck Park, Wonjae Lee, Chang-Hwan Yoon, Jung-Won Suh, Seung-Sik Hwang, Tae-Jin Youn, In-Ho Chae, Hyo-Soo Kim
AIMS: To investigate the long-term safety and efficacy of biodegradable scaffolds and metallic stents. METHODS AND RESULTS: We analyzed a total of 91 randomized controlled trials with a mean follow-up of 3.7 years in 105,842 patients which compared 2 or more coronary metallic stents or biodegradable scaffolds and reported the long-term clinical outcomes (≥2 years). Network meta-analysis showed that patients treated with the Absorb bioresorbable vascular scaffold (BVS) had significantly higher risk of definite or probable scaffold thrombosis (ScT) compared to those treated with metallic DES...
December 26, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29278352/impact-of-diagnostic-ecg-to-wire-delay-in-stemi-patients-treated-with-primary-pci-a-danami-3-substudy
#6
Lars Nepper-Christensen, Jacob Lønborg, Dan Eik Høfsten, Kiril Aleksov Ahtarovski, Kasper Kyhl, Christoffer Göransson, Lars Køber, Steffen Helqvist, Frants Pedersen, Henning Kelbæk, Niels Vejlstrup, Lene Holmvang, Thomas Engstrøm
AIMS: We evaluated the impact of delay from diagnostic pre-hospital electrocardiogram (ECG) to wiring of the infarct related vessel (ECG-to-wire) >120 minutes on cardiovascular magnetic resonance (CMR) markers of reperfusion success and clinical outcome in patients with ST-segment elevation myocardial infarction (STEMI). METHODS AND RESULTS: We included 1492 patients in the analyses of clinical outcome. CMR was performed in 748 patients to evaluate infarct size and myocardial salvage...
December 26, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29278351/controversies-surrounding-authorship-of-manuscripts-by-industry-employees-academic-and-industry-perspectives
#7
Nathaniel R Smilowitz, James J Ferguson, Giora Weisz
AIMS: The medical device and pharmaceutical industries play an essential role in the development of cardiovascular devices and drugs, and industry employees are frequently listed as co-authors of clinical trials published in peer-reviewed journals. Potential conflicts of interest in biomedical research have attracted significant attention in recent years, but issues and challenges surrounding authors who are industry employees have not received nearly as much scrutiny. METHODS AND RESULTS: We present a comprehensive discussion of the concerns and challenges regarding the role of industry in the authorship of scientific manuscripts...
December 26, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29278350/combined-use-of-coils-and-onyx-for-transcatheter-closure-of-coronary-artery-fistula
#8
Pan Li, Xudong Xu, Zheng Zhang, Feiyu Wang, Zhongkai Wang, Feng Chen, Bili Zhang, Yongwen Qin, Shaoping Chen, Xianxian Zhao
AIMS: To evaluate the safety and efficacy of combined of endovascular coiling as well as Onyx embolization in patients with coronary artery fistula (CAF). METHODS AND RESULTS: Between September 2014 and September 2016, 26 patients with CAFs were enrolled in our study for attempted combined therapy using coil and Onyx. The mean age of patients was 64.0±9.5 years (range, 44-78 years). CAFs were large in 10 and medium in 16 patients. The mean number of coils used was 3...
December 26, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29278349/characteristics-of-stent-thrombosis-in-bifurcation-lesions-analyzed-by-optical-coherence-tomography
#9
Mohamed Y Bechiri, Geraud Souteyrand, Thierry Lefèvre, Charlotte Trouillet, Gregoire Rangé, Guillaume Cayla, François Derimay, Lionel Mangin, Nicolas Meneveau, Christophe Caussin, Pascal Motreff, Nicolas Amabile
AIMS: This work aimed to investigate a cohort of patients presenting with stent thrombosis (ST) explored by optical coherence tomography (OCT) to identify the underlying mechanical abnormalities in case of bifurcation lesions. Methids and results: The PESTO study was a prospective national registry involving 29 French catheterization facilities. Patients with acute coronary syndromes were prospectively screened for presence of definite ST and analyzed by OCT after culprit lesion reopening...
December 26, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29260723/compare-and-contrast-tricuspid-and-mitral-valve-anatomy-interventional-perspectives-for-transcatheter-tricuspid-valve-therapies
#10
Maurizio Taramasso, Alberto Pozzoli, Cristina Basso, Gaetano Thiene, Paolo Denti, Shingo Kuwata, Fabian Nietlispach, Ottavio Alfieri, Rebecca T Hahn, Georg Nickenig, Joachim Schofer, Martin B Leon, Mark Reisman, Francesco Maisano
Moving treanscatheter valve intervention towards atrioventricular (AV) valves implies increasing complexity. Part of the knowledge that has been generated during the development of mitral devices can be transferred to the tricuspid valve (TV). A deep understanding of the peculiar anatomy of the TV and of the right heart chambers, with differences and similarities between the two AV valves is fundamental to overcome the specific challenges related to transcatheter TV therapies. The aim of this report is to explore similarities and differences between mitral and tricuspid apparatus, and their interventional implications...
December 19, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29260713/correlates-of-non-target-vessel-related-adverse-events-in-patients-with-st-segment-elevation-myocardial-infarction-insights-from-5-year-follow-up-of-the-examination-trial
#11
Giosafat Spitaleri, Elisabetta Moscarella, Salvatore Brugaletta, Alberto Pernigotti, Luis Ortega-Paz, Josep Gomez-Lara, Angel Cequier, Andrés Íñiguez-Romo, Antonio Serra, Pilar Jiménez-Quevedo, Vicente Mainar, Gianluca Campo, Maurizio Tespili, Peter den Heijer, Armando Bethencourt, Nicolás Vazquez, Marco Valgimigli, Patrick W Serruys, Manel Sabaté
AIMS: to determine the 5-year correlates of non-TV related adverse events (AE) in STEMI patients included in the EXAMINATION trial. METHODS AND RESULTS: the EXAMINATION trial randomized 1498 STEMI patients to bare-metal or everolimus-eluting stent. In this sub-study, patients were analyzed according to non-TV related AE, defined as the composite of either non-TV revascularization (non-TVR) or non-TV related myocardial infarction (MI). At 5-year follow-up, 125 patients (8...
December 19, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29260712/in-vitro-hydrodynamic-and-acute-clinical-performance-of-a-novel-self-expanding-thv-in-various-surgical-bioprostheses
#12
Alexander Sedaghat, Jan-Malte Sinning, Nikos Werner, Georg Nickenig, Lenard Conradi, Stefan Toggweiler, Ulrich Schäfer
AIMS: The aim of this study was to assess the in-vitro hydrodynamic performance of a novel self-expanding transcatheter heart valve prosthesis (THV), the NVT AllegraTM, in 5 different surgical bioprostheses. In addition, we present a series of valve-in-valve implantations in the clinical setting using the 23mm AllegraTM prosthesis. METHODS AND RESULTS: The 23mm NVT AllegraTM was implanted in 5 different surgical bioprostheses of 23mm nominal size, namely the Edwards Perimount, the Sorin MitroFlow, the St...
December 19, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29235436/bioprosthetic-aortic-valve-leaflet-thrombosis-detected-by-multidetector-computed-tomography-is-associated-with-adverse-cerebrovascular-events-a-meta-analysis-of-observational-studies
#13
Hashrul N Rashid, Robert P Gooley, Nitesh Nerlekar, Abdul R Ihdayhid, Liam M McCormick, Arthur Nasis, James D Cameron, Adam J Brown
AIMS: Leaflet thrombosis (LT) has become increasingly recognised following transcatheter and surgical aortic ABV replacement and can be reliably identified by MDCT. However, it is ongoing debate whether MDCT-defined LT is associated with adverse cerebrovascular outcomes. We performed a systematic review and meta-analysis to assess the incidence and clinical outcomes associated with multidetector computed tomography (MDCT)-defined leaflet thrombosis following aortic bioprosthetic valve (ABV) replacement...
December 12, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29235435/transcatheter-aortic-valve-in-valve-treatment-in-prior-sorin-freedom-solo-valve
#14
Mohammed Shamim Rahman, James Cockburn, Uday Trivedi, David Hildick-Smith
No abstract text is available yet for this article.
December 12, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29205158/prognostic-impact-of-non-culprit-chronic-total-occlusions-in-infarct-related-cardiogenic-shock-results-of-the-randomized-iabp-shock-ii-trial
#15
Mohammed Saad, Georg Fuernau, Steffen Desch, Ingo Eitel, Suzanne de Waha, Janine Pöss, Taoufik Ouarrak, Steffen Schneider, Uwe Zeymer, Holger Thiele
AIMS: To investigate the impact of a chronic total occlusion (CTO) in a non-infarct-related coronary artery (non-IRA) on 1-year mortality and occurrence of cardiac arrhythmia in patients with cardiogenic shock (CS) complicating acute myocardial infarction (AMI). METHODS AND RESULTS: In a retrospective sub-analysis of the Intraaortic Balloon Pump in Cardiogenic Shock II trial (IABP-SHOCK II) and its accompanying registry, 201 (26%) of 761 patients had a CTO in a non-IR major coronary artery...
December 5, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29205157/a-comparison-of-an-ultrathin-strut-biodegradable-polymer-sirolimus-eluting-stent-with-a-durable-polymer-everolimus-eluting-stent-for-patients-with-acute-stsegment-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention-rationale
#16
Juan F Iglesias, Olivier Muller, Serge Zaugg, Marco Roffi, David J Kurz, André Vuilliomenet, Daniel Weilenmann, Christoph Kaiser, Maxime Tapponnier, Dik Heg, Marco Valgimigli, Eric Eeckhout, Peter Jüni, Stephan Windecker, Thomas Pilgrim
AIMS: A novel ultrathin-strut biodegradable polymer sirolimus-eluting stent (Orsiro™, Biotronik, Bülach, Switzerland; BP-SES) was shown to be superior to a thin-strut durable polymer everolimus-eluting stent (Xience™ Xpedition/Alpine, Abbott Vascular, Santa Clara, USA; DP-EES) with respect to the primary endpoint of target lesion failure (TLF) at 12 months in the prespecified subgroup of patients with ST-segment elevation myocardial infarction (STEMI) included in the BIOSCIENCE trial...
December 5, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29205156/edge-to-edge-repair-of-a-large-anterior-leaflet-notch-with-severe-tricuspid-regurgitation
#17
Neil P Fam, Edwin C Ho, Jeremy Edwards, Kim A Connelly
No abstract text is available yet for this article.
December 5, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29175771/recovery-of-absolute-coronary-flow-and-resistance-1-week-after-percutaneous-coronary-intervention-of-a-chronic-total-occluded-coronary-artery-using-the-novel-rayflow%C3%A2-infusion-catheter
#18
Daniëlle C J Keulards, Frederik M Zimmermann, Nico H J Pijls, Koen Teeuwen
No abstract text is available yet for this article.
November 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29175770/catheter-based-therapies-in-acute-pulmonary-embolism
#19
Jacob Schultz, Asger Andersen, Christopher Kabrhel, Jens Erik Nielsen-Kudsk
AIMS: To provide a systematic review of catheter-based therapies of acute pulmonary embolism. METHODS AND RESULTS: Studies published in peer-reviewed journals before February 2017 were included and categorized according to the mechanism of thrombus removal: fragmentation, rheolytic therapy, aspiration or catheter-directed thrombolysis. Strengths, challenges and the level of evidence of each device were evaluated. We found 16 different catheter-based therapies for acute PE; all but one being used off-label...
November 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29175769/valve-in-valve-transcatheter-aortic-valve-implantation-into-a-novel-sutureless-bioprosthesis-technical-considerations
#20
Martin Andreas, Iuliana Coti, Guenther Laufer, Johannes Kastner
No abstract text is available yet for this article.
November 28, 2017: EuroIntervention
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