We have located links that may give you full text access.
Nano-based therapy for treatment of skin cancer.
Recent Patents on Anti-infective Drug Discovery 2018 September 11
BACKGROUND: According to the World Health Organization, skin cancer is the most common malignancy for the population. Conventional skin cancer treatment includes surgery and chemotherapy, but many of the chemotherapeutic agents used present undesirable properties. There are number of patents on topical nano formulation like nanoparticle (US9757453; US9457041), liposomes (US2018177726 (A1), has been covered in this review in the treatment of skin cancer.
METHODS: Encapsulated drugs are advantageous due to such properties as high stability, better bioavailability, controlled drug release, a long blood circulation time, selective organ or tissue distribution, a lower total required dose, and minimal toxic side effects. Today, researchers are constantly developing new formulations to meet unmet needs in the delivery of therapeutic agents for cancer therapy and diagnosis, respectively.
RESULTS: Of particular interest here are lipid-based nano formulations that are formulated from varieties of lipid and other chemical components that act collectively to overcome biological barriers, in order to preferentially accumulate in or around disease-target cells for the functional delivery of therapeutic agents. The article deals with recent development of nano sized topical lipid formulation approaches to treat skin cancer.
CONCLUSION: We focus especially on the topical lipid formulation approaches combined with chemotherapy, a field which specialises in target specificity, drug release control, and real time monitoring with the goal being to diminish unwanted side effects and their severity, achieving a cheaper treatment and a generally more efficient chemotherapy.
METHODS: Encapsulated drugs are advantageous due to such properties as high stability, better bioavailability, controlled drug release, a long blood circulation time, selective organ or tissue distribution, a lower total required dose, and minimal toxic side effects. Today, researchers are constantly developing new formulations to meet unmet needs in the delivery of therapeutic agents for cancer therapy and diagnosis, respectively.
RESULTS: Of particular interest here are lipid-based nano formulations that are formulated from varieties of lipid and other chemical components that act collectively to overcome biological barriers, in order to preferentially accumulate in or around disease-target cells for the functional delivery of therapeutic agents. The article deals with recent development of nano sized topical lipid formulation approaches to treat skin cancer.
CONCLUSION: We focus especially on the topical lipid formulation approaches combined with chemotherapy, a field which specialises in target specificity, drug release control, and real time monitoring with the goal being to diminish unwanted side effects and their severity, achieving a cheaper treatment and a generally more efficient chemotherapy.
Full text links
Related Resources
Trending Papers
Executive Summary: State-of-the-Art Review: Unintended Consequences: Risk of Opportunistic Infections Associated with Long-term Glucocorticoid Therapies in Adults.Clinical Infectious Diseases 2024 April 11
Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management.International Journal of Molecular Sciences 2024 April 13
Clinical practice guidelines on the management of status epilepticus in adults: A systematic review.Epilepsia 2024 April 13
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app