We have located links that may give you full text access.
Structural Differences in Hippocampal and Entorhinal Gray Matter Volume Support Individual Differences in First Person Navigational Ability.
Neuroscience 2018 June 2
The ability to update position and orientation to reach a goal is crucial to spatial navigation and individuals vary considerably in this ability. The current structural MRI study used voxel-based morphometry (VBM) analysis to relate individual differences in human brain morphology to performance in an active navigation task that relied on updating position and orientation in a landmark-free environment. Goal-directed navigation took place from either a first person perspective, similar to a person walking through the landmark-free environment, or Survey perspective, a bird's eye view. Critically, the first person perspective required a transformation of spatial information from an allocentric into an egocentric reference frame for goal-directed navigation. Significant structural volume correlations in the hippocampus, entorhinal cortex, and thalamus were related to first person navigational accuracy. Our results support the theory that hippocampus, entorhinal cortex, and thalamus are key structures for updating position and orientation during ground-level navigation. Furthermore, the results suggest that morphological differences in these regions underlie individual navigational abilities, providing an important link between animal models of navigation and the variability in human navigation.
Full text links
Related Resources
Trending Papers
Executive Summary: State-of-the-Art Review: Unintended Consequences: Risk of Opportunistic Infections Associated with Long-term Glucocorticoid Therapies in Adults.Clinical Infectious Diseases 2024 April 11
Clinical practice guidelines on the management of status epilepticus in adults: A systematic review.Epilepsia 2024 April 13
Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management.International Journal of Molecular Sciences 2024 April 13
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app