We have located links that may give you full text access.
Aortic Surgery Outcomes of Marfan Syndrome and Ehlers-Danlos Syndrome Patients at Teaching and Non-Teaching Hospitals.
Annals of Vascular Surgery 2018 October 2
OBJECTIVE: Despite improvements in prevention and management, aortic aneurysm repair remains a high risk operation for patients with Marfan syndrome (MFS) and Ehlers-Danlos syndrome (EDS). The goal of this study was to examine differences in characteristics and outcomes of patients with MFS or EDS undergoing aortic aneurysm repair at teaching versus non-teaching hospitals.
METHODS: We used the National Inpatient Sample to study patients with MFS or EDS undergoing open or endovascular aortic aneurysm repair from 2000 to 2014.
RESULTS: Of 3487 patients (MFS=3375, EDS=112), 2974 (85%) had repair at a teaching hospital. Patients who underwent repair at a teaching hospital were slightly younger than those who underwent repair at a non-teaching hospital (38 vs 43 years, p<0.01) but otherwise were similar in gender (29% vs 28% female), race (70% vs 78% white), and connective tissue disorder diagnosis (97% vs 97% MFS, all p≥0.1). There were no differences in anatomy (17% vs 19% abdominal, 67% vs. 66% thoracic, and 15% vs 15% thoracoabdominal, all p≥0.1) or type of repair (5% vs 5% endovascular), but patients at non-teaching hospitals were more likely to have a dissection (49% vs. 38%, p=0.02). There was no difference in perioperative mortality (4% vs 6%, p=0.5) or length of stay (median 8 days vs. 7 days, p=0.3) between teaching and non-teaching hospitals. There was also no difference in hemorrhagic (47% vs 43%), pulmonary (9% vs 16%), renal (12% vs 14%), or neurologic (5% vs 6%) complications between teaching and non-teaching hospitals respectively (all p≥0.05). In analysis stratified by anatomic extent of repair, there was a lower prevalence of pulmonary complications in thoracic aorta repairs at teaching hospitals (8.1% vs. 18.4%, p=0.01) but a higher prevalence of hemorrhage in abdominal aortic repairs at teaching hospitals (45.6% vs. 20.6%, p=0.04) as compared to non-teaching hospitals.
CONCLUSION: Marfan and Ehlers-Danlos syndrome patients who undergo aortic aneurysm repair have their operations predominantly at teaching hospitals, but those patients who undergo repair at non-teaching hospitals do not have worse mortality or morbidity despite a higher incidence of dissection.
METHODS: We used the National Inpatient Sample to study patients with MFS or EDS undergoing open or endovascular aortic aneurysm repair from 2000 to 2014.
RESULTS: Of 3487 patients (MFS=3375, EDS=112), 2974 (85%) had repair at a teaching hospital. Patients who underwent repair at a teaching hospital were slightly younger than those who underwent repair at a non-teaching hospital (38 vs 43 years, p<0.01) but otherwise were similar in gender (29% vs 28% female), race (70% vs 78% white), and connective tissue disorder diagnosis (97% vs 97% MFS, all p≥0.1). There were no differences in anatomy (17% vs 19% abdominal, 67% vs. 66% thoracic, and 15% vs 15% thoracoabdominal, all p≥0.1) or type of repair (5% vs 5% endovascular), but patients at non-teaching hospitals were more likely to have a dissection (49% vs. 38%, p=0.02). There was no difference in perioperative mortality (4% vs 6%, p=0.5) or length of stay (median 8 days vs. 7 days, p=0.3) between teaching and non-teaching hospitals. There was also no difference in hemorrhagic (47% vs 43%), pulmonary (9% vs 16%), renal (12% vs 14%), or neurologic (5% vs 6%) complications between teaching and non-teaching hospitals respectively (all p≥0.05). In analysis stratified by anatomic extent of repair, there was a lower prevalence of pulmonary complications in thoracic aorta repairs at teaching hospitals (8.1% vs. 18.4%, p=0.01) but a higher prevalence of hemorrhage in abdominal aortic repairs at teaching hospitals (45.6% vs. 20.6%, p=0.04) as compared to non-teaching hospitals.
CONCLUSION: Marfan and Ehlers-Danlos syndrome patients who undergo aortic aneurysm repair have their operations predominantly at teaching hospitals, but those patients who undergo repair at non-teaching hospitals do not have worse mortality or morbidity despite a higher incidence of dissection.
Full text links
Related Resources
Trending Papers
Executive Summary: State-of-the-Art Review: Unintended Consequences: Risk of Opportunistic Infections Associated with Long-term Glucocorticoid Therapies in Adults.Clinical Infectious Diseases 2024 April 11
Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management.International Journal of Molecular Sciences 2024 April 13
Clinical practice guidelines on the management of status epilepticus in adults: A systematic review.Epilepsia 2024 April 13
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app