Mineralization of Dentinal Lesions with Different Concentrations of Fluoride.

OBJECTIVES: The present study aimed to investigate the relationship between fluoride concentration and mineral distribution within the dentinal lesion body.

METHODS: Remineralization of artificial deep dentinal lesions with various levels of fluoride was studied using a scanning electron microscope, microhardness tests, and polarized light microscope. Human molars were exposed to demineralization at pH 5.0 for 2 weeks. Then, they were divided into different groups for remineralization with different fluoride concentrations (0.1-10.0 ppm) for 1, 2, 3, and 4 weeks.

RESULTS: The results indicated a proportional relationship between fluoride concentration and dentinal lesion remineralization from 0.1 to 10.0 ppm. In the present study, the formation of a well-remineralized surface layer inhibited remineralization at the lesion front. On the other hand, the lesion front remineralization was found to be independent of fluoride concentration.

CONCLUSION: Our results stated that for effective remineralization of dentinal lesions to the innermost part, fluoride levels from 1.0 to 5.0 ppm have the highest efficiency.