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https://www.readbyqxmd.com/read/28093269/invasive-disease-versus-urinary-antigen-confirmed-pneumococcal-community-acquired-pneumonia
#1
Adrian Ceccato, Antoni Torres, Catia Cilloniz, Rosanel Amaro, Albert Gabarrus, Eva Polverino, Elena Prina, Carolina Garcia-Vidal, Eva Muñoz-Conejero, Cristina Mendez, Isabel Cifuentes, Jorge Puig de la Bella Casa, Rosario Menendez, Michael S Niederman
OBJECTIVES: The burden of pneumococcal disease is measured only through patients with invasive pneumococcal disease. The urinary antigen test (UAT) for pneumococcus has exhibited a high sensitivity and specificity. We aimed to compare the pneumococcal pneumonias diagnosed as invasive disease with pneumococcal pneumonias defined by UAT. METHODS: Prospective observational study on consecutive non-immunosuppressed patients with community-acquired pneumonia from January 2000 to December 2014...
January 13, 2017: Chest
https://www.readbyqxmd.com/read/28093268/bronchiectasis-rheumatoid-overlap-syndrome-bros-is-an-independent-risk-factor-for-mortality-in-patients-with-bronchiectasis-a-multicentre-cohort-study
#2
Anthony De Soyza, Melissa J McDonnell, Pieter C Goeminne, Stefano Aliberti, Sara Lonni, John Davison, Lieven J Dupont, Thomas C Fardon, Robert M Rutherford, Adam T Hill, James D Chalmers
INTRODUCTION: We studied if Bronchiectasis (BR) and Rheumatoid arthritis (RA) when manifesting as an overlap syndrome (BROS) was associated with worse outcomes than other BR aetiologies applying the Bronchiectasis Severity Index (BSI). METHODS: We interrogated the Bronchiectasis Severity Index (BSI) databases of 1716 patients across 6 centres: Edinburgh, UK (608 patients), Dundee, UK (N=286), Leuven, Belgium (N=253), Monza, Italy (N=201), Galway Ireland (N=242) and Newcastle, UK (N=126)...
January 13, 2017: Chest
https://www.readbyqxmd.com/read/28089817/patient-centered-specialty-practice-defining-the-role-of-specialists-in-value-based-healthcare
#3
REVIEW
Lawrence Ward, Rhea E Powell, Michael L Scharf, Andrew Chapman, Mani Kavuru
Healthcare is at a crossroads, under pressure to add value by improving patient experience and health outcomes and reducing costs to the system. Efforts to improve the care model in primary care, such as the patient-centered medical home, have enjoyed some success. Yet primary care accounts for only a small portion of total healthcare spending, and there is a need for policies and frameworks to support high quality, cost-efficient care in specialty practices of the "medical neighborhood". The Patient-Centered Specialty Practice (PCSP) model offers ambulatory-based specialty practices one such framework, supported by a formal recognition program through the National Committee for Quality Assurance...
January 13, 2017: Chest
https://www.readbyqxmd.com/read/28089816/can-high-flow-nasal-cannula-reduce-the-rate-of-endotracheal-intubation-in-adult-patients-with-acute-respiratory-failure-compared-with-conventional-oxygen-therapy-and-noninvasive-positive-pressure-ventilation-a-systematic-review-and-meta-analysis
#4
Yue-Nan Ni, Jian Luo, He Yu, Dan Liu, Ni Zhong, Jiangli Cheng, Bin-Miao Liang, Zong-An Liang
BACKGROUND: The effects of high flow nasal cannula (HFNC) on adult patients with acute respiratory failure (ARF) are controversial. We aimed to further determine the effectiveness of HFNC in reducing the rate of endotracheal intubation in adult patients with ARF by comparison to noninvasive positive pressure ventilation (NIPPV) and conventional oxygen therapy (COT). METHODS: The Pubmed, Embase, Medline, Cochrane Central Register of Controlled Trials (CENTRAL) as well as the Information Sciences Institute (ISI) Web of Science were searched for all the controlled studies that compared HFNC with NIPPV and COT in adult patients having ARF...
January 13, 2017: Chest
https://www.readbyqxmd.com/read/28089815/do-patients-hospitalized-with-copd-have-airflow-obstruction
#5
Huimin Wu, Robert A Wise, Ann E Medinger
BACKGROUND: Guidelines recommend the confirmation of a COPD diagnosis with spirometry. ICD-9-CM diagnostic codes are used frequently to identify patients with COPD for administrative purposes. However, coding the diagnosis of COPD does not require spirometric confirmation. The purpose of this study was to determine how often the discharge diagnoses of COPD is supported by spirometric measurements in the VA health system. METHODS: We reviewed records of patients hospitalized for COPD in a VA teaching hospital between 2005 and 2015...
January 13, 2017: Chest
https://www.readbyqxmd.com/read/28087304/sleep-and-neurodegeneration-a-critical-appraisal
#6
REVIEW
Jagan A Pillai, James B Leverenz
Sleep abnormalities are clearly recognized as distinct clinical symptom of concern in neurodegenerative disorders. Appropriate management of sleep related symptoms has a positive impact on the quality of life of patients with neurodegenerative disorders. This review provides an overview of mechanisms that are currently being considered that tie sleep with neurodegeneration. It appraises the literature regarding specific sleep changes among common neurodegenerative diseases with a focus on Alzheimer's disease and synucleinopathies (i...
January 10, 2017: Chest
https://www.readbyqxmd.com/read/28087303/activity-levels-and-exercise-motivation-in-copd-patients-and-their-resident-loved-ones
#7
Rafael Mesquita, Nienke Nakken, Daisy J A Janssen, Esther H A van den Bogaart, Jeannet M L Delbressine, Johannes M N Essers, Kenneth Meijer, Monique van Vliet, Geeuwke J de Vries, Jean W M Muris, Fabio Pitta, Emiel F M Wouters, Martijn A Spruit
BACKGROUND: Resident loved ones of patients with COPD can play an important role in helping patients to engage in physical activity. We aimed to compare activity levels and exercise motivation between COPD patients and their resident loved ones; to compare the same outcome measures in patients after stratification for the physical activity level of the loved ones; and to predict the likelihood of being physically active in patients with a physically active resident loved one. METHODS: 125 patient-loved one dyads were cross-sectionally and simultaneously assessed...
January 10, 2017: Chest
https://www.readbyqxmd.com/read/28087302/the-long-term-effect-of-bacille-calmette-gu%C3%A3-rin-vaccination-on-tuberculin-skin-testing-a-55-year-follow-up-study
#8
James D Mancuso, Rupal M Mody, Cara H Olsen, Lee H Harrison, Mathuram Santosham, Naomi E Aronson
BACKGROUND: Bacille Calmette-Guérin vaccination (BCG) is known to cause false positive tuberculin skin test (TST) results from cross-reactions to mycobacterial antigens. However, the duration of BCG influence on the TST is poorly characterized. The objective of the study was to assess the long-term effect of BCG vaccination on TST reactivity. METHODS: Data on TST reactivity were prospectively collected during 1935-47 as part of a clinical trial among American Indians / Alaskan Natives and retrospectively thereafter between 1948 and 1998...
January 10, 2017: Chest
https://www.readbyqxmd.com/read/28040521/bronchodilator-response-in-fvc-is-larger-and-more-relevant-than-in-fev1-in-severe-airflow-obstruction
#9
Philip H Quanjer, Gregg L Ruppel, Arnulf Langhammer, Abhishek Krishna, Frans Mertens, Ane Johannessen, Ana M B Menezes, Fernando C Wehrmeister, Rogelio Perez-Padilla, Maureen P Swanney, Wan C Tan, Jean Bourbeau
BACKGROUND: Recommendations on interpreting tests of bronchodilator responsiveness (BDR) are conflicting. We investigated the dependence of BDR criteria on sex, age, height, ethnicity and severity of respiratory impairment. METHODS: BDR tests were available from clinical patients in the Netherlands, New Zealand and the USA (N=15,278, 51.7% females) and surveys in Canada, Norway and five Latin-American countries (N=16,250, 54.7% females). BDR in FEV1, FVC and FEV1/ FVC was expressed as absolute change, % baseline, % predicted and z-score...
December 28, 2016: Chest
https://www.readbyqxmd.com/read/28025056/non-malignant-pleural-effusions-nmpe-a-prospective-study-of-356-consecutive-unselected-patients
#10
Steven P Walker, Anna J Morley, Louise Stadon, Duneesha De Fonseka, David A Arnold, Andrew Rl Medford, Nick A Maskell
BACKGROUND: Pleural effusions secondary to a non-malignant aetiology can represent significant morbidity and mortality. These non-malignant pleural effusions (NMPE) are common, with congestive heart failure (CHF) representing the leading cause. Despite this, there is limited data on mortality risk and the factors which influence them. METHODS: We recruited 782 consecutive patients presenting to a pleural service, between 03/2008 and 03/2015, with an undiagnosed pleural effusion...
December 23, 2016: Chest
https://www.readbyqxmd.com/read/28065564/rebuttal-from-dr-hemnes
#11
EDITORIAL
Anna R Hemnes
No abstract text is available yet for this article.
December 22, 2016: Chest
https://www.readbyqxmd.com/read/28065563/point-should-wireless-pulmonary-artery-hemodynamic-monitoring-be-used-to-monitor-patients-with-pulmonary-hypertension-yes
#12
EDITORIAL
Mark Jay Zucker
No abstract text is available yet for this article.
December 22, 2016: Chest
https://www.readbyqxmd.com/read/28065562/rebuttal-from-dr-zucker
#13
EDITORIAL
Mark Jay Zucker
No abstract text is available yet for this article.
December 22, 2016: Chest
https://www.readbyqxmd.com/read/28065561/counterpoint-should-wireless-pulmonary-artery-hemodynamic-monitoring-be-used-to-monitor-patients-with-pulmonary-hypertension-no
#14
EDITORIAL
Anna R Hemnes
No abstract text is available yet for this article.
December 22, 2016: Chest
https://www.readbyqxmd.com/read/28012804/improved-cough-and-cough-specific-quality-of-life-in-patients-treated-for-scleroderma-related-interstitial-lung-disease-ssc-ild-results-of-scleroderma-lung-study-ii
#15
Donald P Tashkin, Elizabeth R Volkmann, Chi-Hong Tseng, Michael D Roth, Dinesh Khanna, Daniel E Furst, Philip J Clements, Arthur Theodore, Suzanne Kafaja, Grace Hyun Kim, Jonathan Goldin, Edgar Ariolla, Robert M Elashoff
BACKGROUND: Cough is a common symptom of scleroderma-related interstitial lung disease (SSc-ILD), but its relationship to other characteristics of SSc-ILD, impact on cough-specific QoL and response to therapy for SSc-ILD have not been well studied. METHODS: We investigated frequent cough (FC) in SSc-ILD patients (N=142) enrolled in Scleroderma Lung Study II, a randomized controlled trial comparing mycophenolate mofetil (MMF) and oral cyclophosphamide (CYC) as treatments for ILD...
December 22, 2016: Chest
https://www.readbyqxmd.com/read/28041890/point-should-only-primary-care-physicians-provide-shared-decision-making-services-to-discuss-the-risks-benefits-of-a-low-dose-chest-ct-for-lung-cancer-screening-yes
#16
EDITORIAL
https://www.readbyqxmd.com/read/28041889/rebuttal-from-dr-goodson
#17
EDITORIAL
John D Goodson
No abstract text is available yet for this article.
December 21, 2016: Chest
https://www.readbyqxmd.com/read/28041888/rebuttal-from-dr-powell
#18
EDITORIAL
Charles A Powell
No abstract text is available yet for this article.
December 21, 2016: Chest
https://www.readbyqxmd.com/read/28041887/counterpoint-should-only-primary-care-physicians-provide-shared-decision-making-services-to-discuss-the-risks-benefits-of-a-low-dose-chest-ct-for-lung-cancer-screening-no
#19
EDITORIAL
https://www.readbyqxmd.com/read/28012806/shift-work-and-shift-work-sleep-disorder-clinical-and-organizational-perspectives
#20
REVIEW
Emerson M Wickwire, Jeanne Geiger-Brown, Steven M Scharf, Christopher L Drake
Throughout the industrialized world, nearly one in five employees works some form of non-traditional shift. Such shift work is associated with numerous negative health consequences, ranging from cognitive complaints to cancer, as well as diminished quality of life. Further, a substantial percentage of shift workers develop shift work disorder (SWD), a circadian rhythm sleep disorder characterized by excessive sleepiness, insomnia, or both as a result of shift work. In addition to adverse health consequences and diminished quality of life at the individual level, SWD incurs significant costs to employers through diminished workplace performance and increased accidents and errors...
December 21, 2016: Chest
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