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A Kamat, Crispin Thompson, Mohammed Ben Husien
[This retracts the article DOI: 10.7759/cureus.401.].
January 22, 2018: Curēus
Nqobile S Thango, A Kamat, Mohamed Ben Husein, David Welsh
[This retracts the article DOI: 10.7759/cureus.391.].
January 22, 2018: Curēus
Sagar Panthi, Kishor Khatri, Krishna Kharel, Raju Vaishya, Amit Kumar Agarwal, Vipul Vijay
[This retracts the article DOI: 10.7759/cureus.953.].
December 13, 2017: Curēus
Georg A Weidlich, M Bret Schneider, John R Adler
The Zap-X is a self-contained and first-of-its-kind self-shielded therapeutic radiation device dedicated to brain as well as head and neck stereotactic radiosurgery (SRS). By utilizing an S-band linear accelerator (linac) with a 2.7 megavolt (MV) accelerating potential and incorporating radiation-shielded mechanical structures, the Zap-X does not typically require a radiation bunker, thereby saving SRS facilities considerable cost. At the same time, the self-shielded features of the Zap-X are designed for more consistency of radiation protection, reducing the risk to radiation workers and others potentially exposed from a poorly designed or constructed radiotherapy vault...
December 6, 2017: Curēus
Razia Awan, Haider Ghazanfar, Karen A Martes Pena, Rafi I Farkhad
Chondrocalcinosis is a common arthritic disorder among elderly patients. We present a case of a 71-year-old woman presenting with an acute episode of the left forearm with hand swelling. A provisional diagnosis of cellulitis was made and the patient was started on intravenous antibiotics. The patient's condition did not improve. Joint aspiration of the wrist joint was done and showed positive birefringent rhomboid-shaped crystals. A final diagnosis of acute chondrocalcinosis was made.
December 6, 2017: Curēus
Pradeep J Christopher, Senthilnathan Periasamy, Poorna Devadoss, Santhosh P Kumar
This case report presents the removal of complex composite odontoma in a young patient in the right body of mandible via the unilateral sagittal splitting of the mandible. This article shows that sagittal split osteotomy of the mandible can be very useful to access various pathologies in the body, angle, and ramus of the mandible and to navigate lesions that are in proximity to the inferior alveolar nerve. This technique also helps in avoiding postoperative morbidity when compared to other conventional surgical approaches...
December 6, 2017: Curēus
Zubair M Amin, Kerry Anne Rambaran, Steven W Fleming, Kevin Cho, Liza Chacko, Saeed K Alzghari
Increased experimentation with easily accessible synthetic opioids is posing a hazard to the public. We discuss one such synthetic opioid, U-50488. Much is unknown about U-50488; however, due to its structural similarity to U-47700, there is possible risk associated with its use. Curtailing the use of synthetic opioids such as U-50488 will require a concerted effort targeting multiple problems.
December 6, 2017: Curēus
Andrew King, Chad Mayer, Andrew Starnes, Kelly Barringer, Lancelot Beier, Harsh Sule
Each year, residency programs work diligently to identify the best applicants for their respective programs, given the increasing volume of applications. Interview offers are often based on a mix of subjective and objective measures, with different programs relying more or less on each. A holistic application review involves a flexible and individualized way of assessing an applicant's capabilities through a balanced consideration of experiences, attributes, and academic metrics. When considered collectively, these attributes may define how an individual may perform as a physician...
December 6, 2017: Curēus
Nilesh H Pawar, Ealing Loke, Derrick C Aw
Spinal cord infarction (SCI) is a rare type of stroke. The initial magnetic resonance imaging (MRI) is usually normal and can mimic the presentation of the acute transverse myelitis (ATM), acute inflammatory demyelinating polyneuropathy, and compressive myelopathies from neoplasm, epidural or subdural hematoma, or abscess. The aim of this report is to describe and discuss the case of a patient with SCI presenting as a diagnostic confusion with acute transverse myelitis. A 64-year-old male with a medical history of hypertension presented with an acute onset of urinary retention with lower limb weakness...
December 6, 2017: Curēus
Madeeha Subhan, Waleed Sadiq
Infectious diseases are one of the major causes of morbidity and mortality in developing countries. Typhoid has its own contribution to the disease burden, especially in Pakistan and other tropical countries. Herein, we present a case of enteric fever with a rare presentation. Our patient is a 20-year-old man who gradually developed high-grade fever lasting seven days associated with rigors and chills. No additional accompanying systemic signs helped to localize the infection. After extensive laboratory testing, his typhoid serology was positive along with leukocytopenia and thrombocytopenia...
December 6, 2017: Curēus
Gregory D Sloop, Joseph J Weidman, John A St Cyr
The authors hypothesize that thrombosis causes both the complications of atherosclerosis as well as the underlying lesion, the atherosclerotic plaque, which develops from the organization of mural thrombi. These form in areas of slow blood flow, which develop because of flow separation created by changing vascular geometry and elevated blood viscosity. Many phenomena typically ascribed to inflammation or "chronic oxidative stress", such as the development of fatty streaks, "endothelial dysfunction," "vulnerable plaques," and the association of mild elevations of C-reactive protein and cytokines with atherothrombosis are better explained by hemorheologic and hemodynamic abnormalities, particularly elevated blood viscosity...
December 5, 2017: Curēus
Hale Z Toklu, Jacklyn C Fuller
Scholarly activities (i.e., the discovery of new knowledge; development of new technologies, methods, materials, or uses; integration of knowledge leading to new understanding) are intended to measure the quality and quantity of dissemination of knowledge. A successful mentorship program is necessary during residency to help residents achieve the six core competencies (patient care, medical knowledge, practice-based learning and improvement, systems-based practice, professionalism, interpersonal and communication skills) required by the Accreditation Council for Graduate Medical Education (ACGME)...
December 5, 2017: Curēus
Homa Timlin, Laurence Magder, Michelle Petri
Background and objective The rate of end-stage renal disease from lupus nephritis has not declined, in spite of recent advances in therapeutics, such as mycophenolate mofetil (MMF). To provide insight into rates of the clinical outcomes in current practice after biopsy-proven lupus nephritis, we used a prospective cohort of the patients with newly diagnosed lupus nephritis, treated with MMF and observed their outcomes. Method Twenty systemic lupus erythematosus (SLE) patients who began mycophenolate mofetil shortly after a biopsy-confirmed diagnosis of lupus nephritis were included in the analysis...
December 4, 2017: Curēus
Fatima Ezzeddine, Shadia Jalal
Spontaneous pneumothoraces and hemothoraces are rare manifestations of sarcomas occurring more commonly in specific histologic types, chemotherapy and/or anti-angiogenic therapy. Early identification of spontaneous pneumothoraces and hemothoraces improves the clinical outcomes. In this article, we present a case series of three patients with soft tissue and bone sarcomas who developed spontaneous pneumothoraces and/or hemothoraces and discuss the current literature highlighting the evidence behind these complications...
December 3, 2017: Curēus
Chong Yau Ong, Farhad F Vasanwala
Immune thrombocytopaenia (also known as idiopathic thrombocytopaenic purpura) (ITP) is a chronic condition with isolated low platelet counts. Although it is largely perceived that ITP predisposes to bleeding risks, thrombotic events, such as ischaemic strokes, do happen paradoxically in patients with ITP. A 68-year-old lady presented with right upper limb weakness and was diagnosed with an ischaemic stroke and was started on clopidogrel. She had a history of ITP. Two months later, she again had another ischaemic stroke...
December 3, 2017: Curēus
Ahmed Nahari, Salem M AlGhamdi, Abdulsalam Alawfi, Hassan Faqeehi, Saeed Alzahrani, Amani Abu-Shaheen, Abdulrahman Al-Hussaini
Background In Saudi Arabia, there is a lack of recently published, appropriately conducted epidemiological studies on rotavirus (RV) diarrhea, which emphasizes the need for up-to-date and comprehensive studies. Objective Our objective was to provide more recent data on the clinical and epidemiological characteristics as well as the economic burden of RV diarrhea among young children admitted to a tertiary care hospital in the city of Riyadh in the year prior to the initiation of the RV vaccine. Design We conducted a prospective observational study at a children's specialized hospital at King Fahad Medical City...
December 2, 2017: Curēus
Hiroshi Doi, Shogo Harui, Hiroki Nakajima, Akira Ando, Keiji Kamino, Masayuki Fujiwara, Takayoshi Nakajima, Shinichi Ikura, Tsukasa Aihara, Naoki Yamanaka
A 0.5%-iron-containing fiducial marker, Gold AnchorTM (Naslund Medical AB, Huddinge, Sweden), has been recently developed. Herein, we report our initial experiences with the clinical use of the Gold AnchorTM (GA) in radiotherapy for liver tumors. Data of four consecutive patients with liver tumors, including two liver metastases and two hepatocellular carcinomas, were retrospectively analyzed. The GA was percutaneously placed under local anesthesia, close to the tumor. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (MRI) was performed after the placement of the GA...
December 1, 2017: Curēus
Carlo Aleci, Marzia Piccoli, Valentina Melotti, Elena Melis, Lorenzo Canavese
Purpose A model aimed at detecting the proportion of visuoperceptive and visuomotor coordination impairment in children with ascertained or suspected learning disability is described. The final purpose is to provide customized rehabilitation programs. Methods In this pilot study, four children (8-9 years) were administered a set of standardized tests to evaluate their ability to perform visuoperceptive and visuomotor tasks. Depending on the individual outcomes, two indexes have been computed from the resulting z-scores: η (Eta) that quantifies the visuoperceptive impairment, and μ (Mu) that expresses the alteration in visuomotor coordination...
December 1, 2017: Curēus
Aditya Mahadevan, Matthew C Strehlow, Khandregzen Dorjsuren, Jennifer A Newberry
Background Soft skills are essential for employee success in the global marketplace; however, many developing countries lack content experts to provide the requisite instruction to an emerging workforce. One possible solution is to use an online, open-access curriculum. To date, no studies on soft skills curricula using an online learning platform have been undertaken in Mongolia. Objective To evaluate the efficacy of an online versus classroom platform to deliver a novel soft skills course in Mongolia. Methods A series of eight lectures along with corresponding surveys and multiple choice question tests were developed and translated into the Mongolian language...
November 30, 2017: Curēus
Jeet J Mehta, Arjun K Mahendran, Ravi K Bajaj, Arpan R Doshi
A 16-year-old male presented to the emergency department with chest pain after smoking a synthetic cannabinoid from a vape pen. He had rising troponin I levels, and his exercise stress echocardiogram showed distal apical and septal hypokinesis that resolved at six-month follow-up. This case report raises concern about cardiac ischemia related to synthetic cannabinoid abuse in the pediatric population in the current era of cannabis legalization.
November 30, 2017: Curēus
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