Xylooligosaccharides from lignocellulosic biomass and their applications as nutraceuticals: a review on their production, purification, and characterization.

Xylooligosaccharides (XOS) are considered a potent source of prebiotics for humans. The global prebiotic market is expanding in size, was valued at USD 6.05 billion in 2021, and is expected to grow at a 14.9% compound annual growth rate (CAGR) between 2022 and 2030, indicating a huge demand. These XOS are non-digestible pentose sugar oligomers comprising mainly xylose. Xylose is naturally present in the lignocellulosic biomass (LCB), fruits, and vegetables. Apart from the prebiotic effect, these XOS have been reported to reduce blood cholesterol, antioxidant effect, increase calcium absorption, reduction of colon cancer risk, and benefit diabetic patients. Primary use of XOS is reported in the feed industry followed by health, medical use, food, and drinks. LCB mainly contains glucan, xylan, and lignin. After glucan, xylan is the second-highest available sugar on the globe composed of xylose. Therefore, the xylan fraction of LCB has great significance in producing food, feed, and energy. Glucan has been exploited for the commercial production of ethanol, xylitol, furfural, hydroxymethyl furfural, and glucose. Whereas as of now xylan has limited applications. Therefore, xylan can be exploited to convert to XOS. Production of XOS from LCB fraction not only helps to produce these at a very low price but also helps in the reduction of greenhouse gases. Its use in food and drinks is increasing as it can be derived from the abundantly and cheaply available LCB. The article provides review on production, purification, and characterization of XOS in view of their use as nutraceuticals. This article is protected by copyright. All rights reserved.