Abu Tayab Moin, Tanjin Barketullah Robin, Rajesh B Patil, Nurul Amin Rani, Anindita Ash Prome, Tahsin Islam Sakif, Mohabbat Hossain, Dil Umme Salma Chowdhury, Shah Samiur Rashid, A K M Moniruzzaman Mollah, Saiful Islam, Mohammad Helal Uddin, Mohammad Khalequzzaman, Tofazzal Islam, Nazneen Naher Islam
Rice blast disease, caused by the fungus Magnaporthe oryzae, poses a severe threat to rice production, particularly in Asia where rice is a staple food. Concerns over fungicide resistance and environmental impact have sparked interest in exploring natural fungicides as potential alternatives. This study aimed to identify highly potent natural fungicides against M. oryzae to combat rice blast disease, using advanced molecular dynamics techniques. Four key proteins (CATALASE PEROXIDASES 2, HYBRID PKS-NRPS SYNTHETASE TAS1, MANGANESE LIPOXYGENASE, and PRE-MRNA-SPLICING FACTOR CEF1) involved in M...
2024: PloS One