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Trevor J Fish, Abby D Benninghoff
Data in this article depict patterns of methylation in lung tissues obtained from the offspring of B6129SF1/J dams and 129S1/SvImJ sires exposed in utero to benzo[a]pyrene (BaP) or dibenzo[def,p]chrysene (DBC) as compared to non-exposed offspring. Genome-wide methylation of lung tumors in adult offspring was determined using methylated DNA immunoprecipitation (MeDIP) with the NimbleGen mouse DNA methylation CpG island array. This data article refers to the research article "DNA methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons," [1] in which comprehensive data interpretation and analysis are provided...
August 2017: Data in Brief
Zahir Qamar, Sardar Khan, Anwarzeb Khan, Muhammad Aamir, Javed Nawab, Muhammad Waqas
Vehicle-wash wastewater (VWW) contains elevated concentrations of different petrochemicals including polycyclic aromatic hydrocarbons (PAHs), a carcinogenic group of organic compounds. This study investigates the discharge of PAHs present in the untreated wastewater of vehicle-wash stations (VWS) located in district Peshawar, Pakistan. The data obtained was being novel with the detection of 16 USEPA PAHs (both individuals and total) and compared with earlier studies and international standards. The ∑16PAHs in wastewater from light vehicle-wash stations (LVWS) and heavy vehicle-wash stations (HVWS) ranged from 245-429μg/l and 957-1582μg/l, respectively...
June 26, 2017: Science of the Total Environment
Víctor Alonso García Londoño, Cora Marcela Reynoso, Silvia Resnik
Polycyclic aromatic hydrocarbons (PAHs) occurrence in forty-four samples of milk powder, marketed in Uruguay was determined. A high performance liquid chromatography (HPLC) method was applied with fluorescence detector (FLD) and UV-VIS diodes array detector (DAD). Milk powder was fortified with PAHs at three levels producing average recovery higher than 78.6% for all levels. The highest concentration of benzo(a)pyrene (BaP) was 2.85 μg kg(-1) in milk powder. Contamination of samples expressed as the sum of 16 analysed PAHs varied between 5...
June 29, 2017: Food Additives & Contaminants. Part B, Surveillance
Siti Khalijah Mahmad Rozi, Hamid Rashidi Nodeh, Muhammad Afzal Kamboh, Ninie Suhana Abdul Manan, Sharifah Mohamad
A novel adsorbent, palm fatty acid coated magnetic Fe3O4 nanoparticles (MNP-FA) was successfully synthesized with immobilization of the palm fatty acid onto the surface of MNPs. The successful synthesis of MNP-FA was further confirmed by X-Ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR) and Energy dispersive X-Ray spectroscopy (EDX) analyses and water contact angle (WCA) measurement. This newly synthesized MNP-FA was applied as magnetic solid phase extraction (MSPE) adsorbent for the enrichment of polycyclic aromatic hydrocarbons (PAHs), namely fluoranthene (FLT), pyrene (Pyr), chrysene (Cry) and benzo(a)pyrene (BaP) from environmental samples prior to High Performance Liquid Chromatography- Diode Array Detector (HPLC-DAD) analysis...
June 13, 2017: Journal of Oleo Science
Fabrice Gritti, Mike Leal, Thomas McDonald, Martin Gilar
The full baseline separation of two compounds (selectivity factors α<1.03) is either impractical (too long analysis times) or even impossible when using a single column of any length given the pressure limitations of current LC instruments. The maximum efficiency is that of an infinitely long column operated at infinitely small flow rates. It is determined by the maximum allowable system pressure, the column permeability (particle size), the viscosity of the eluent, and the intensity of the effective diffusivity of the analytes along the column...
June 10, 2017: Journal of Chromatography. A
Graciel Diamante, Gabrielle do Amaral E Silva Müller, Norma Menjivar-Cervantes, Elvis Genbo Xu, David C Volz, Afonso Celso Dias Bainy, Daniel Schlenk
One of the primary sources of polycyclic aromatic hydrocarbons (PAHs) in marine environments is oil. Photochemical oxidation and microbial transformation of PAH-containing oils can result in the formation of oxygenated products. Among the PAHs in crude oil, chrysene is one of the most persistent within the water column and may be transformed to 2- and 6-hydroxychrysene (OHCHR). Both of these compounds have been shown to activate (2-OHCHR) and antagonize (6-OHCHR) the estrogen receptor (ER). Previous studies in our lab have shown that estrogen can significantly alter zebrafish development...
June 3, 2017: Aquatic Toxicology
Ke-Jing An, Yu-Lan Liu, Hai-Lan Liu
Deep-fried dough sticks (a Chinese traditional breakfast) were fried individually in peanut, sunflower, rapeseed, rice bran, soybean and palm oil without any time lag for 32 h (64 batches fried, each for 30 min) and fried oil samples were obtained every 2 h. The frying-induced changes in the levels of total polar compounds (TPC) and polycyclic aromatic hydrocarbons (PAHs) were investigated by edible oil polar compounds (EOPC) fast separation chromatographic system and gas chromatography-mass spectrometry (GC-MS), respectively...
June 20, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Shunpei Nobusue, Kazuya Fujita, Yoshito Tobe
Treatment of a twisted polycyclic aromatic hydrocarbon containing cyclooctatetraene fused by two 9,9'-bifluorenylidene units under the Scholl reaction conditions (FeCl3 or 2,3-dichloro-5,6-dicyano-1,4-benzoquinone and scandium trifluoromethanesulfonate) led to stepwise skeletal rearrangements to afford initially a hydrocarbon with a seven-membered ring and then tetrabenzo[a,d,j,m]coronene with all six-membered rings. The course of the rearrangement was interpreted in terms of the acid-catalyzed isomerization of 9,9'-bifluorenylidene into dibenzo[g,p]chrysene moieties on the basis of theoretical investigations...
June 6, 2017: Organic Letters
Xiao Qian, Baocui Liang, Xuan Liu, Xinhui Liu, Juan Wang, Fei Liu, Baoshan Cui
The distribution, sources, and ecological risk of polycyclic aromatic hydrocarbons (PAHs) were investigated in surface sediments from the Haihe River. Total PAH concentrations varied from 171.4 to 9511.2 ng g(-1) with an average of 2125.4 ng g(-1), suggesting serious pollution of the Haihe River in comparison with other reported rivers worldwide. PAH contaminants differed significantly among 17 sampling locations with high values occurring in industrial areas and densely populated areas. The composition of PAHs was characterized by high abundance of 4-ring and 5-ring PAHs, and benzo[a]anthracene, chrysene, and benzo[a]pyrene were the predominant components...
July 2017: Environmental Science and Pollution Research International
Pil-Gon Kim, Ji-Yeon Roh, Yongseok Hong, Jung-Hwan Kwon
Passive sampling can be applied for measuring the freely dissolved concentration of hydrophobic organic chemicals (HOCs) in soil pore water. When using passive samplers under field conditions, however, there are factors that might affect passive sampling equilibrium and kinetics, such as soil water saturation. To determine the effects of soil water saturation on passive sampling, the equilibrium and kinetics of passive sampling were evaluated by observing changes in the distribution coefficient between sampler and soil (Ksampler/soil) and the uptake rate constant (ku) at various soil water saturations...
May 31, 2017: Chemosphere
N Grova, F Faÿs, E M Hardy, B M R Appenzeller
A gas chromatography tandem mass-spectrometry method dedicated to the analysis of 50 metabolites of polycyclic aromatic hydrocarbons (OH-PAHs) was applied to urine specimens collected from female Long Evans rats under controlled exposure to a mixture of PAHs (at 7 doses ranging from 0.01 to 0.8 mg/kg, by gavage, 3 times per week for 90 days). On four occasions (day 1, 28, 60 and 90), urine samples were collected over a 24 h period. Among these 50 OH-PAHs, 41 were detected in urine samples. Seven additional OH-PAHs were identified for the first time: 1 corresponding to metabolite of pyrene and 3 of anthracene...
May 30, 2017: Environmental Pollution
Karianne Skogland Enerstvedt, Magne O Sydnes, Daniela M Pampanin
Occurrence of polycyclic aromatic hydrocarbon (PAH) contamination in the marine environment represents a risk to marine life and humans. In this study, plasma samples from Atlantic cod (Gadus morhua) were analysed by shotgun mass spectrometry to investigate the plasma proteome in response to exposure to single PAHs (naphthalene or chrysene) and their corresponding metabolites (dihydrodiols). In total, 369 proteins were identified and ranked according to their relative abundance. The levels of 12 proteins were found significantly altered in PAH exposed fish and are proposed as new biomarker candidates...
May 19, 2017: Chemosphere
K Olof Johansson, Matthew F Campbell, Paolo Elvati, Paul E Schrader, Judit Zádor, Nicole K Richards-Henderson, Kevin R Wilson, Angela Violi, Hope A Michelsen
We have measured photoionization-efficiency curves for pyrene, fluoranthene, chrysene, perylene, and coronene in the photon energy range of 7.5-10.2 eV and derived their photoionization cross-section curves in this energy range. All measurements were performed using tunable vacuum ultraviolet (VUV) radiation generated at the Advanced Light Source synchrotron at Lawrence Berkeley National Laboratory. The VUV radiation was used for photoionization, and detection was performed using a time-of-flight mass spectrometer...
June 15, 2017: Journal of Physical Chemistry. A
Carmela Lestingi, Tamara Tavoloni, Valentina Bardeggia, Monia Perugini, Arianna Piersanti
A gas-chromatographic single quadrupole analytical method for the analysis of the sixteen priority EU polycyclic aromatic hydrocarbons (PAHs) in food is presented in this paper. The method fulfils the request of Regulation EU 836/2011 for an analytical procedure to be used for official control of PAHs in food, in EU member states. The sample preparation involves a Pressurised Liquid Extraction (PLE) with an in-cell clean-up step followed by a lipid removal using SPE on a styrene divinylbenzene stationary phase (SDVB) and a final gel permeation chromatography (GPC) step...
May 17, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Bi-Cheng Yang, Shu-Fen Fang, Xiao-Ju Wan, Yong Luo, Jiang-Yan Zhou, You Li, Yun-Jun Li, Feng Wang, Ou-Ping Huang
Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants with carcinogenic effect raising worldwide concerns. Hydroxylated PAHs (OH-PAHs) could be formed in the body as metabolites of PAHs in human urine samples and thus considered as biomarkers of PAH exposure. In this study, five OH-PAHs including 3-phenanthrol, 1-naphthol, 2-hydroxy fluorene, 1-hydroxprene and 6-hydroxy chrysene in human urine samples were selectively enriched by C18 solid-phase microextraction (SPME), then SPME fiber was connected high voltage and then was inserted into a glass-capillary to elute and ionize the analytes for mass spectrometric (MS) detection...
June 22, 2017: Analytica Chimica Acta
Trevor J Fish, Abby D Benninghoff
Polycyclic aromatic hydrocarbons (PAHs) comprise an important class of environmental pollutants that are known to cause lung cancer in animals and are suspected lung carcinogens in humans. Moreover, evidence from cell-based studies points to PAHs as modulators of the epigenome. The objective of this work was to assess patterns of genome-wide DNA methylation in lung tissues of adult offspring initiated in utero with the transplacental PAH carcinogens dibenzo [def,p]chrysene (DBC) or benzo [a]pyrene (BaP). Genome-wide methylation patterns for normal (not exposed), normal adjacent and lung tumor tissues obtained from adult offspring were determined using methylated DNA immunoprecipitation (MeDIP) with the NimbleGen mouse DNA methylation CpG island array...
May 2, 2017: Food and Chemical Toxicology
Linlin Yao, Luqing Pan, Ruiming Guo, Jingjing Miao
Aquatic organisms are increasingly exposed to polycyclic aromatic hydrocarbons (PAHs) due to anthropogenic pressure. This study aimed at evaluating the response of Glutathione S-transferases (GSTs) in scallop Chlamys farreri against benzo[a]pyrene (BaP) and chrysene (CHR) exposure under laboratory conditions. Nine published GST genes were classified into six subfamilies and a new member of rho family was identified for the first time. Twelve GSTs (including nine published GST genes and three in transcriptome established by our laboratory) mRNA transcript levels in the gills, digestive glands, adductor muscle, mantle, testis, ovaries, blood cells of scallops were measured by real-time PCR...
August 2017: Ecotoxicology and Environmental Safety
Marco Capolupo, Silvia Franzellitti, Alisar Kiwan, Paola Valbonesi, Enrico Dinelli, Emanuela Pignotti, Manfred Birke, Elena Fabbri
This study aimed at evaluating the environmental quality of a coastal lagoon (Pialassa Piomboni, NW-Adriatic, Italy) by combining analyses of biomarkers of environmental stress and bioaccumulation of contaminants in marine mussels (Mytilus galloprovincialis) transplanted for 28days to six selected sites. Assessed biomarkers encompassed lysosomal endpoints, oxidative stress and detoxification parameters, specific responses to metals, neuro- and genotoxic substances; chemical analyses focused on PAHs, metals, pesticide and pharmaceuticals...
November 15, 2017: Science of the Total Environment
Xuan Zhang, Zhanqiang Xu, Weili Si, Kazuaki Oniwa, Ming Bao, Yoshinori Yamamoto, Tienan Jin
The extended polycyclic aromatic hydrocarbons (PAHs) have received significant interdisciplinary attention due to their semiconducting applications in diverse organic electronics as well as intriguing structural interests of well-defined graphene segments. Herein, a highly efficient oxidative spirocyclization and 1,2-aryl migration tandem synthetic method for the construction of extended polyaromatic hydrocarbons (PAHs) has been developed. The CuCl-catalyst/PhCO3(t)Bu or DDQ oxidation system in the presence of trifluoroacetic acid enables the selective single-electron oxidation to take place preferentially at the more electron-rich alkene moiety of o-biphenylyl-substituted methylenefluorenes, giving rise to the subsequent tandem process...
April 25, 2017: Nature Communications
Małgorzata Wroniak, Agnieszka Rękas
The purpose of this study was to investigate the levels of polycyclic aromatic hydrocarbons [benzo(a)anthracene, chrysene, benzo(b)fluoranthene, and benzo(a)pyrene], polychlorinated biphenyls (6 marker and 12 dioxin-like), pesticides (74 compounds) and heavy metals (Pb, Cd, As, Hg, Fe, Cu), in the cold-pressed rapeseed oils from conventional (RC) and ecological cultivations (RE). Similar level of PAHs, PCBs and heavy metals was found in the investigated cold-pressed oils; moreover, no effect of rapeseeds cultivation practice on the level of pesticide residues was found...
April 2017: Journal of Food Science and Technology
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