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Michał Bialik, Artur Wiktor, Piotr Latocha, Ewa Gondek
The aim of this study was to analyze the impact of osmotic solutions and temperature on the osmotic dehydration (OD) of two cultivars of kiwiberry. OD was carried out in sucrose, xylitol and maltitol solutions at 30 °C and 50 °C, respectively. The process of osmotic dehydration was described by the means of water loss (WL), solid gain (SG), weight reduction (WR), and water content changes. Moreover, dehydration was described by mathematical models often used in the literature. The highest WL, WR and SG values were observed for samples treated by xylitol and maltitol at 50 °C...
May 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Eun Ju Yun, Eun Joong Oh, Jing-Jing Liu, Sora Yu, Dong Hyun Kim, Suryang Kwak, Kyoung Heon Kim, Yong-Su Jin
Background: Understanding the global metabolic network, significantly perturbed upon promiscuous activities of foreign enzymes and different carbon sources, is crucial for systematic optimization of metabolic engineering of yeast Saccharomyces cerevisiae . Here, we studied the effects of promiscuous activities of overexpressed enzymes encoded by foreign genes on rerouting of metabolic fluxes of an engineered yeast capable of assimilating sugars from renewable biomass by profiling intracellular and extracellular metabolites...
2018: Biotechnology for Biofuels
Haiming Wu, Ziyang Li, Hai Liu
In this study, polyhydric alcohols, including glycerol, erythritol, xylitol, mannitol, and inositol, were chosen as carbon precursors for preparation of carbon adsorbents via phosphoric acid activation. The thermal behaviors of phosphoric acid-treated polyhydric alcohols revealed the formation and decomposition of organic phosphates at low temperatures, which enhanced the creation of functional groups on activated carbon. In general, the activated carbons showed relative low surface area (the highest one of 509 m2 /g for AC-xylitol) due to the low activation temperature, and low yields (the highest one of 36...
April 30, 2018: Chemosphere
Aline-Bastos da Silva, Nayre-Maria-Lauande Rapôso, Isabella-Azevedo Gomes, Letícia-Machado Gonçalves, Marco-Aurélio-Benini Paschoal
Background: The widespread use of mouthwashes, specially in children, is a concern, since the long-term use may modify the topography of dental materials. However, this process still unclear regarding the wear related to infant mouthwashes on glass ionomer cement. Thus, the purpose of this investigation was evaluate the erosive potential of infant mouthwashes on glass ionomer cement specimens. Material and Methods: Forty round-shaped specimens were divided into 4 groups (N=10) and submitted to erosive cycling for 15 days, being exposed 2X/day in the following children's active agents mouthwash solutions: G1- cetylpyridinium chloride, G2- xylitol and triclosan and G3 - Malva sylvestris and xylitol...
March 2018: Journal of Clinical and Experimental Dentistry
Jian Guo, Siyao Huang, Yefu Chen, Xuewu Guo, Dongguang Xiao
BACKGROUND: Aureobasidium pullulans is a yeast-like fungus that can ferment xylose to generate high-value-added products, such as pullulan, heavy oil, and melanin. The combinatorial expression of two xylose reductase (XR) genes and two xylitol dehydrogenase (XDH) genes from Spathaspora passalidarum and the heterologous expression of the Piromyces sp. xylose isomerase (XI) gene were induced in A. pullulans to increase the consumption capability of A. pullulans on xylose. RESULTS: The overexpression of XYL1...
April 30, 2018: Microbial Cell Factories
Francis Marchal
Rhinology : balloon sinuplasty and its potential commercial links ; factors of recurrence of sinunasal polyposis ; olfactory dysfunction and biofilms. Otology : effect of music and headphones on children ; vaccination and otitis media. Pharyngo-laryngology : interest of DISE (Drug Induce Sleep Endoscopy) in case of Sleep Apnea Syndrome; adenotonsillectomy and interest of robotic surgery.Salivary glands : presence of Helicobacter pylori in buccal cavity ; pepsin testing in saliva in case of reflux ; antibacterial effect of xylitol ; interest of propolis in treating candidosis...
April 25, 2018: Revue Médicale Suisse
Masahiro Kurakake, Yukari Amai, Mizuki Konishi, Kaho Ikehira
β-N-Acetylhexosaminidase was identified from Bacillus sp. CH11 and found to have relatively high transferring activity. In this study, its enzymatic properties and transglycosylation activity including its acceptor specificity were investigated. Its molecular weight was estimated to be 90 kDa by SDS-PAGE and its optimal pH was approximately 7 with good stability from pH 6 to 8. Its optimal temperature was 40 °C, and its activity was stable at temperatures of up to 40 °C. To analyze its acceptor specificity for transglycosylation, N, N'-diacetylchitobiose was used as a donor substrate and alcohols, sugar alcohols, sugars and polyphenols were used as acceptors...
April 6, 2018: Journal of Food Science
Silvana Rissi, Roselei Claudete Fontana, Mateus Arduvino Reck, Rosa Mara Borges da Silveira, Aldo José Pinheiro Dillon, Marli Camassola
The potential to produce ethanol and xylitol from xylose by the macro basidiomycete Trametes membranacea was evaluated. All strains studied showed ethanol and xylitol production. The highest ethanol production of xylose was obtained by T. membranacea strain TM158/10 with 5.65 ± 0.21 g/L at pH 4 and 28 °C with 288 h of fermentation and 5.59 ± 0.05 g/L ethanol concentration at pH 5 and 24 °C with 360 h of fermentation. When the conversion was carried out using sugars generated from enzymatic hydrolysis of sugarcane bagasse, there were higher yields from 74 to 15% for ethanol and xylitol, respectively...
April 3, 2018: Bioprocess and Biosystems Engineering
Yuki Tazawa, Keisuke Kagami, Yuko Watanabe, Kosei Kubota, Sachiko Harada, Masaki Kobayashi, Takehiro Yamada, Ken Iseki
 Indomethacin (IM) oral spray is a hospital preparation that is used to reduce pain from oral mucositis induced by radiotherapy and chemotherapy. IM oral spray consists of IM (0.25%) dissolved in KH2 PO4 -NaOH buffer (Formulation A) or Formulation A containing xylitol (Xyl) and glycerin (Gly) (Formulation B). To clarify the stability of IM oral spray in two different formulation conditions, we evaluated the residual rates of IM in these formulations to determine the optimal storage temperature and shelf-life...
2018: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
Tomoko Kemmei, Shuji Kodama, Atsushi Yamamoto, Yoshinori Inoue, Kazuichi Hayakawa
In this study, we developed a simple and sensitive reversed phase ion-pair chromatographic method for the analysis of C4-C6 sugar alcohols. The method is based on the on-line complexation of sugar alcohols with molybdate ion. The resulting dinuclear anionic complexes can be separated on a reversed-phase C18 column using tetrabutylammonium chloride as an ion-pairing reagent. The mobile phase (pH 3.1) consisted of 0.1 mM disodium molybdate, 1 mM hydrochloric acid and 0.4 mM tetrabutylammonium chloride - 10% v/v methanol...
March 12, 2018: Journal of Chromatography. A
Cristiane Patricia Pissinato Pere, Sophia N Economidou, Gurprit Lall, Clémentine Ziraud, Joshua S Boateng, Bruce D Alexander, Dimitrios A Lamprou, Dennis Douroumis
In this study, polymeric microneedle patches were fabricated by stereolithography, a 3D printing technique, for the transdermal delivery of insulin. A biocompatible resin was photopolymerized to build pyramid and cone microneedle designs followed by inkjet print coating of insulin formulations., trehalose and xylitol were used as drug carriers with the aim to preserve insulin integrity and stability but also facilitate rapid release rates. Circular dichroism and Raman analysis demonstrated that all carriers maintained the native form of insulin with xylitol presenting the best performance...
March 16, 2018: International Journal of Pharmaceutics
Weizheng Wang, Feng Chen, Yaqi Wang, Lina Wang, Haiyan Fu, Fuping Zheng, Lance Beecher
Reducing sugars have strong reactivity with 1-phenyl-3-methyl-5-pyrazolone (PMP) to form the sugar-PMP derivatives, which can be more accurately analyzed by HPLC-UV at 248 nm. Glucose and glucosamine reacted with the PMP based on the response surface methodology within a range of temperature between 60 °C and 80 °C, and time between 60 and 180 min. The optimal conditions for the glucose-PMP and glucosamine-PMP reactions were obtained at 71 °C for 129 min, and 73 °C for 96 min, respectively...
July 15, 2018: Food Chemistry
Aylin W Sahin, Claudia Axel, Emanuele Zannini, Elke K Arendt
Burger buns are a source of added sugar, containing 7-12%, in order to ensure their unique texture and taste. Hence, suitable sugar substitutes for burger buns are urgently needed. This study aimed to elucidate the effect of three different polyols on dough and product quality of burger buns. Xylitol, mannitol and maltitol were incorporated individually in a burger bun system, by replacing added sucrose by 30%, 50% and 100%. Wheat starch was used to compare the impact of polyols with another non-sweet bulking agent...
April 25, 2018: Food & Function
K Geirhos, P Lunkenheimer, A Loidl
Experimental evidence for the Gardner transition, theoretically predicted to arise deep in the glassy state of matter, is scarce. At this transition, the energy landscape sensed by the particles forming the glass is expected to become more complex. In the present Letter, we report the dielectric response of two typical glass formers with well-pronounced Johari-Goldstein β relaxation, following this response down to unprecedented low temperatures, far below the glass transition. As the Johari-Goldstein process is believed to arise from the local structure of the energy landscape, its investigation seems an ideal tool to seek evidence for the Gardner transition...
February 23, 2018: Physical Review Letters
Chandran Sathesh-Prabu, Sung Kuk Lee
The production of α,ω-dicarboxylic acids (DCAs) by whole-cell biocatalysis is often limited by cofactor regeneration. Here, ω-oxidation pathway genes (monooxygenase, alcohol dehydrogenase, and aldehyde dehydrogenase) were coexpressed with a xylose reductase (XR) gene to regenerate cofactors in an engineered Escherichia coli strain that cometabolizes glucose and xylose. The resulting strain exhibited a 180% increase in DCA production compared with the control strain without XR, and produced xylitol in the presence of xylose...
April 4, 2018: Journal of Agricultural and Food Chemistry
Edit Páyer, Judit Szabó-Papp, Lídia Ambrus, Attila Gábor Szöllősi, Mónika Andrási, Shabtay Dikstein, Lajos Kemény, István Juhász, Andrea Szegedi, Tamás Bíró, Attila Oláh
Polyols (e.g. glycerol, xylitol) are implicated as moisturizers of the skin and other epithelial tissues. However, we lack information about their exact cellular mechanisms and their effects on the gene expression profiles. Therefore, in this study, we aimed at investigating the effects of glycerol and xylitol on human epidermal keratinocytes. The polyols (identical osmolarities; xylitol: 0.0045%-0.45%; glycerol: 0.0027%-0.27%) did not alter cellular viability or intracellular calcium concentration. However, they exerted differential effects on the expression of certain genes and signalling pathways...
March 2018: Experimental Dermatology
E Arat Maden, C Altun, G Guven Polat, F Basak
Aim: The aim of this study was to evaluate the effect of fluoride, Xylitol, Probiotic, and Whitening toothpastes on the permanent teeth enamel roughness and microhardness. Materials and Methods: One hundred and twenty teeth were randomly divided into 2 groups, each group having 60 samples. G1: The group in which enamel roughness was examined (n = 60). G2: The group in which enamel microhardness was examined (n = 60). Then, these groups were randomly divided into 4 groups among themselves (n = 15)...
March 2018: Nigerian Journal of Clinical Practice
Chika Ifeanyi Chukwuma, Shahidul Islam
The present study investigated the anti-oxidative effects of xylitol both in vitro and in vivo in normal and type 2 diabetes (T2D) rat model. Free radical scavenging and ferric reducing potentials of different concentrations of xylitol were investigated in vitro. For in vivo study, six weeks old male Sprague-Dawley rats were divided into four groups, namely: Normal Control (NC), Diabetic Control (DBC), Normal Xylitol (NXYL) and Diabetic Xylitol (DXYL). T2D was induced in the DBC and DXYL groups. After the confirmation of diabetes, a 10% xylitol solution was supplied instead of drinking water to NXYL and DXYL, while normal drinking water was supplied to NC and DBC ad libitum...
May 2017: Acta Poloniae Pharmaceutica
Ping Yang, Wu Jun Long, Li Wei
Background: A number of studies with conflicting results have evaluated the effect of chewing gum on post-operative gastrointestinal recovery in patients after major colorectal surgery. Objective: The objective of the study was to study the efficacy of chewing gum in patients with rectal cancer after elective open proctectomy only. Methods: A randomized controlled clinical trial was performed. We recruited patients who would undergo elective open proctectomy for rectal cancer in Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Giorgia Pertile, Jacek Panek, Karolina Oszust, Anna Siczek, Magdalena Frąc
The aim of the study was an analysis of the intraspecific genetic and functional diversity of the new isolated fungal strains of P. setifera . This is the first report concerning the genetic and metabolic diversity of Petriella setifera strains isolated from industrial compost and the first description of a protocol for AFLP fingerprinting analysis optimised for these fungal species. The results showed a significant degree of variability among the isolates, which was demonstrated by the clearly subdivision of all the isolates into two clusters with 51% and 62% similarity, respectively...
2018: PeerJ
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