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Pancytopenia following adjuvant therapy with interferon gamma (IFN-γ) in a patient with disseminated nocardiosis.
International Journal of Infectious Diseases : IJID 2024 March 7
A patient with disseminated nocardiosis developed pancytopenia after treatment with recombinant interferon gamma (IFN-γ). While no prior clinical reports link pancytopenia to IFN-γ, our observations align with basic research on myelosuppressive effects of IFN-γ. Adjunctive IFN-γ may improve standard nocardiosis therapy, but vigilant monitoring of its hematological effects is necessary.
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