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International Journal of Infectious Diseases: IJID

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https://www.readbyqxmd.com/read/29793039/antimicrobial-resistance-in-the-context-of-the-syrian-conflict-drivers-before-and-after-the-onset-of-conflict-and-key-recommendations
#1
REVIEW
Aula Abbara, Timothy M Rawson, Nabil Karah, Wael El-Amin, James Hatcher, Bachir Tajaldin, Osman Dar, Omar Dewachi, Ghassan Abu Sitta, Bernt Eric Uhlin, Annie Sparrow
Current evidence describing antimicrobial resistance (AMR) in the context of the Syrian conflict is of poor quality and sparse in nature. In this paper we explore and report the major drivers of AMR that were present in Syria pre-conflict and those that have emerged since its onset in March 2011. Drivers which existed before the conflict included a lack of enforcement of existing legislation to regulate over the counter antibiotics and notification of communicable diseases. This contributed to a number of drivers of AMR after the onset of conflict which were also compounded by the exodus of trained staff, the increase in overcrowding and unsanitary conditions, the increase in injuries and economic sanctions limiting the availability of required laboratory medical materials and equipment...
May 21, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29793038/therapeutic-drug-monitoring-and-safety-of-voriconazole-therapy-in-patients-with-child-pugh-class-b-and-c-cirrhosis-a-multicenter-study
#2
Taotao Wang, Miao Yan, Dan Tang, Ling Xue, Tao Zhang, Yuzhu Dong, Li Zhu, Xinggang Wang, Yalin Dong
OBJECTIVES: The purpose of this study was to investigate the pharmacokinetic profile and safety of voriconazole treatment in patients with Child-Pugh class B and C cirrhosis. METHODS: Liver cirrhosis patients receiving recommended voriconazole maintenance dose (group A) and halved maintenance dose (group B) orally or intravenously were involved. Voriconazole-related adverse events (AEs) were defined according to Common Terminology Criteria for Adverse Events. RESULTS: A total of 110 voriconazole Cmin were monitored from 78 patients...
May 21, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29783175/hiv-viral-suppression-in-oman-encouraging-progress-toward-achieving-the-united-nations-third-90
#3
Ali Elgalib, Samir Shah, Zeyana Al-Habsi, Maha Al-Fouri, Halima Al-Sawafi, Jalila Al-Noumani, Adil Al-Baloushi, Saad Al-Alawi, Salma Al-Badi, Zainab Mohammed, Jokha Al-Ghafri, Asma Suleimani, Huda Al-Mashani, Jyothish Raju, Saada Al-Riyami, Muna Al-Shukri, Abdul Wahab, Bilal Hussain, Khalifa Al-Naabi, Anantha Narayan, Noreen Oliveros, George Prasad, Ahmed Hussein, Rajeev Kashyp, Khalid Al-Shardi, Ahmed Nada, Shakil Akhwand, Bina Kamble, Kawthar Al-Aamri, Suad Al-Mukhaini, Hanan Al-Kindi, Faryal Khamis, Amal Al-Maani, Idris Al-Abaidani, Seif Al-Abri
OBJECTIVE: To assess the impact of capacity-building interventions introduced by the Oman National AIDS Programme on the quality of HIV care in the country. METHODS: HIV viral load (VL) suppression and loss to follow-up (LTFU) rates were calculated for the period before (in December 2015; n=1098) and after (in June 2017; n=1185) the introduction of the interventions: training, support, and care pathway development. Three HIV VL cuts-offs at last measurement in the year of interest were used to define VL suppression...
May 18, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29782922/dengue-chikungunya-and-zika-infections-imported-to-paris-between-2009-and-2016-characteristics-and-correlation-with-outbreaks-in-the-french-overseas-territories-of-guadeloupe-and-martinique
#4
Victor Vasquez, Elie Haddad, Alice Perignon, Stéphane Jaureguiberry, Ségolène Brichler, Isabelle Leparc-Goffart, Eric Caumes
BACKGROUND: Dengue (DV), chikungunya (CV) and Zika virus (ZV) infections are rapidly expanding across countries and diagnosed in returned travelers who represent epidemiological sentinels. French Territories of America (FTA) such as Guadeloupe and Martinique are highly touristic places and have experienced three consecutive outbreaks by such viruses in the last decade. OBJECTIVE: We evaluated how ill returned travelers could be deemed as epidemiological sentinels for these three expanding arboviral diseases during eight consecutive years...
May 18, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29778583/a-novel-view-on-the-pathogenesis-of-complications-after-intravesical-bcg-for-bladder-cancer
#5
Manu P Bilsen, Krista E van Meijgaarden, Hanna K de Jong, Simone A Joosten, Corine Prins, Lucia J M Kroft, Jacqueline T Jonker, Stijn Crobach, Rob C Pelger, Tom H M Ottenhoff, Sandra M Arend
Intravesical Bacillus Calmette-Guérin (BCG) is widely used for high-risk, non-muscle-invasive bladder cancer. We describe four cases which illustrate the spectrum of BCG-induced complications, varying from granulomatous prostatitis to sepsis. Considerable debate exists whether inflammation or infection is the predominant mechanism in the pathogenesis of BCG-disease. In two patients with systemic illness symptoms resolved first after adding prednisone, indicating a principle role for inflammation in systemic disease...
May 17, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29772272/letter-to-the-editor-on-a-rare-case-of-candida-glabrata-spondylodiscitis-case-report-and-literature-review-by-gagliano-et-al
#6
LETTER
Jeroen G V Habets J, Onno P M Teernstra, Wouter L W van Hemert, Catharina K Linssen, Roel J J Heijboer, Kim Rijkers
No abstract text is available yet for this article.
May 14, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29758278/prevalence-of-and-risk-factors-associated-with-latent-tuberculosis-in-singapore-a-cross-sectional-survey
#7
Peiling Yap, Kristin Hui Xian Tan, Wei Yen Lim, Timothy Barkham, Linda Wei Lin Tan, Mark Chen I-Cheng, Yee Tang Wang, Cynthia Bin Eng Chee
OBJECTIVES: We performed the first LTBI cross-sectional survey in Singapore, utilizing the QuantiFERON Gold In-tube (QFT-GIT) assay to collect data on the prevalence of LTBI and identify potential risk factors associated with it. METHODS: Nation-wide household addresses were randomly selected for enumeration, where Singaporeans or Permanent Residents (PRs), aged 18-79 years, were identified. One eligible member per household was selected using the Kish grid. Each participant answered a questionnaire, assessing medical history (including TB), socio-economic factors and lifestyle and provided a blood specimen for the QFT-GIT assay...
May 11, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29753877/developing-a-decision-support-system-for-patients-with-severe-infection-conditions-in-prehospital-care
#8
Niclas Johansson, Carl Spindler, John Valik, Veronica Vicente
OBJECTIVE: To develop and validate a prehospital decision support system (DSS) for the emergency medical services (EMS), enabling identification and steering of patients with critical infectious conditions - severe respiratory tract infections, severe CNS-infections and sepsis - to a specialized emergency department (ED) for infectious diseases. METHODS: The development process has involved four consecutive steps. The first step was gathering data from the electronic Patient Care Record on patients transported by the EMS, to identify retrospectively appropriate patient categories for steering...
May 10, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29753119/replicative-virus-shedding-in-the-respiratory-tract-of-the-patients-with-middle-east-respiratory-syndrome-coronavirus-infection
#9
Wan Beom Park, Leo Lm Poon, Su-Jin Choi, Pyoeng Gyun Choe, Kyoung-Ho Song, Ji Hwan Bang, Eu Suk Kim, Hong Bin Kim, Sang Won Park, Nam Joong Kim, Malik Peiris, Myoung-Don Oh
BACKGROUND: Information on the duration of replicative Middle East respiratory syndrome coronavirus (MERS-CoV) shedding is important for infection control. Detection of MERS-CoV subgenomic mRNAs indicates the virus is replicative. We examined the duration for detecting MERS-CoV subgenomic mRNA compared with genomic RNA in diverse respiratory specimens METHODS: From upper and lower respiratory samples of 17 MERS-CoV-infected patients, MERS-CoV subgenomic mRNA was detected by reverse transcription polymerase chain reaction (RT-PCR) and MERS-CoV genomic RNA was done by real time RT-PCR...
May 9, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29751112/identification-and-molecular-typing-of-naegleria-fowleri-from-a-patient-of-primary-amebic-meningoencephalitis-pam-in-china
#10
Ling-Ling Zhang, Mao Wu, Bang-Chuan Hu, Hua-Liang Chen, Jin-Ren Pan, Wei Ruan, Li-Nong Yao
Naegleria fowleri (N. fowleri) is the only Naegleria spp. known to cause an acute, fulminant, and rapidly fatal central nervous system infection called primary amebic meningoencephalitis (PAM) in human. In 2016, a suspected PAM patient was found in Zhejiang Province of China. The pathogen was identified by microscopic examination and PCR. The positive PCR products were sequenced and the sequences were aligned using NCBI BLAST programme. The homologous and phylogenetic analysis was conducted using the MEGA 6 programme...
May 8, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29746903/randomized-clinical-trial-of-famciclovir-or-acyclovir-for-the-treatment-of-herpes-zoster-in-adults
#11
Henrique Pott Junior, Monalisa F Bocchi de Oliveira, Sheley Gambero, Roberto Bleuel Amazonas
BACKGROUND: This study investigated the safety and effectiveness of famciclovir compared to acyclovir in patients with herpes zoster to determine if both regimens are equally suited to treat uncomplicated herpes zoster patients for 7 days. METHODS: Patients were randomly assigned to receive either Famciclovir 500mg (one tablet) t.i.d. or Acyclovir 800mg (two capsules) five times daily for 7 days. The primary endpoint was defined as the time to full crusting of herpes zoster lesions...
May 7, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29746902/paracoccidioidomycosis-simulating-crohn-s-disease
#12
José Y Rodríguez, Gerson J Rodríguez, Carlos A Álvarez-Moreno, Victor G Ramirez
No abstract text is available yet for this article.
May 7, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29738826/co-infection-with-zika-and-chikungunya-viruses-associated-with-fetal-death
#13
Arnaldo Prata-Barbosa, Thaís Lira Cleto-Yamane, Jaqueline Rodrigues Robaina, Andrea Bittencourt Guastavino, Maria Clara de Magalhães-Barbosa, Rodrigo de Moraes Brindeiro, Roberto Andrade Medronho, Antonio José Ledo Alves da Cunha
We describe a case of fetal death associated with a recent infection by Chikungunya virus (CHIKV) in a Brazilian pregnant woman (positive RT-PCR in blood and placenta). Zika virus (ZIKV) infection during pregnancy was also identified, based on a positive RT-PCR in a fetal kidney specimen. The maternal infection caused by the ZIKV was asymptomatic and the CHIKV infection had a classical clinical presentation. The fetus had no apparent anomalies, but her weight was between the 3rd and 10th percentile for the gestational age...
May 5, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29738825/the-fifth-influenza-a-h7n9-epidemic-a-family-cluster-of-infection-in-suzhou-city-of-china-2016
#14
Jiajia Wang, Nan Su, Zefeng Dong, Cheng Liu, Pengwei Cui, Jian-An Huang, Cheng Chen, Yehan Zhu, Liling Chen
OBJECTIVE: Influenza A(H7N9) virus is known for its high pathogenicity in human. A family cluster of influenza A(H7N9) virus infection was identified in Suzhou, China. This study aimed to investigate the possibility of human-to-human transmission of the virus and examine the virologic features of this family cluster. METHODS: The clinical and epidemiologic data of two patients in the family cluster of influenza A(H7N9) virus infection were collected. Viral RNA in samples derived from the two patients, their close contacts, and the environments with likely influenza A(H7N9) virus transmission were tested by real-time reverse transcriptase polymerase chain reaction (rRT-PCR) assay...
May 5, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29730383/fulminant-septic-shock-caused-by-capnocytophaga-canimorsus-in-italy-case-report
#15
Giorgio Piccinelli, Francesca Caccuri, Elena De Peri, Andrea Tironi, Silvia Odolini, Lucia Dora Notarangelo, Franco Gargiulo, Francesco Castelli, Nicola Latronico, Fabio Facchetti, Arnaldo Caruso
Capnocytophaga canimorsus infection was recently recognized as a zoonosis. We report the first case of fulminant septic shock in Italy caused by this pathogen. The patient, with a history of splenectomy, died at the main hospital in Brescia with a presumptive diagnosis of sepsis. PCR and sequencing on post mortem samples confirmed C. canimorsus as a causative organism. Our purpose is to alert medical professionals to the virulence of C. canimorsus in asplenic and immunocompromised patients.
May 3, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29730382/medical-imagery-isolated-abducens-palsy-due-to-acute-sphenoid-sinusitis
#16
Oscar H Del Brutto, Rafael Caputi
No abstract text is available yet for this article.
May 3, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29730381/timeliness-in-the-notification-of-spotted-fever-in-brazil-evaluating-compulsory-reporting-strategies-and-digital-disease-detection
#17
Stefan Vilges de Oliveira, Rodrigo Nogueira Angerami
Spotted fever caused by rickettsial species, the most important tick-borne disease. In Brazil, is nationwide communicable compulsory disease to the Ministry of Health. Since 2007, all suspected cases of spotted fever have been integrated into the Notifiable Diseases Information System (SINAN). In this descriptive study we evaluate the timeliness (expressed in number of days between time of clinical suspicion and reporting) of the compulsory notification of spotted fever cases in SINAN and the strategy for digital disease detection (DDD)...
May 3, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29702266/genome-sequence-of-mycobacterium-yongonense-rt-955-2015-isolate-from-a-patient-misdiagnosed-with-multi-drug-resistant-tuberculosis-first-clinical-isolate-in-tanzania
#18
Nicholaus Peter Mnyambwa, Dong-Jin Kim, Esther Ngadaya, Jongsik Chun, Sung-Min Ha, Pammla Petrucka, Kennedy Kwasi Addo, Rudovick R Kazwala, Sayoki G Mfinanga
BACKGROUND: Mycobacterium yongonense is a recently described novel species belonging to Mycobacterium avium complex which is the most prevalent etiology of non-tuberculous mycobacteria associated with pulmonary infections, and posing tuberculosis diagnostic challenges in high-burden, resource-constrained settings. METHODS: We used whole genome shotgun sequencing and comparative microbial genomic analyses to characterize the isolate from a patient diagnosed with multi-drug resistant tuberculosis (MDR-TB) after relapse...
April 24, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29702265/cost-of-managing-meningitis-and-encephalitis-among-adult-patients-in-the-united-states
#19
J M Balada-Llasat, Ning Rosenthal, Rodrigo Hasbun, Louise Zimmer, Christine C Ginocchio, Steven Duff, Jessica Chung, Samuel Bozzette
OBJECTIVES: To determine the associated cost related to diagnosis and treatment of meningoencephalitis (ME) in adult patients in the United States. METHODS: A retrospective observational study design was used to assess the use and costs of diagnostic tests, antimicrobial treatment and total hospitalization for adult patients with suspected ME who received a lumbar puncture (LP) procedure during an emergency department visit or during the first two service days of an inpatient stay...
April 24, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29702264/severe-laryngeal-and-pulmonary-tuberculosis-under-anti-tnf-alpha-therapy
#20
Alexie Bosch, Anne Conrad, Carine Fuchsmann, Bénédicte Prot, Oana Dumitrescu, Tristan Ferry, Christian Chidiac, Florence Ader, Florent Valour
No abstract text is available yet for this article.
April 24, 2018: International Journal of Infectious Diseases: IJID
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