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International Journal of Infectious Diseases: IJID

Farida Almarzooqi, Aysha Alkhemeiri, Ahmed Aljaberi, Rayhan Hashmey, Taoufik Zoubeidi, Abdul-Kader Souid
OBJECTIVES: Intense migrations from tuberculosis endemic areas to Gulf countries create special risks to people in the region. The purpose of this study is to provide data that could justify implementing a universal, regular TB screening in UAE. DESIGN: This prospective, cross-sectional study used interferon-γ release assay (IGRA) to screen for TB among Emirati citizens between August-2016 and May-2017; expatriates were not included in this study. Participants were recruited from Emiratis attending Tawam Hospital Polyclinics for problems unrelated to TB risk assessment...
March 8, 2018: International Journal of Infectious Diseases: IJID
Yongming Zhou, Jingyun Zhang, Shukun Wang, Wen Xu, Weili Liang, Meiying Yan, Duochun Wang, Baowei Diao, Bo Pang, Xin Lu, Fenxia Fan, Jie Li, Jing Lou, Li Zhang, Ruibai Wang, Xiaoying Cui, Meng Zhao, Rui Wu, Hongyan Cai, Xiaoli Du, Zhigang Cui, Wenpeng Gu, Rusong Yang, Biao Kan
OBJECTIVES: To conduct a one-year pathogen surveillance of acute diarrheal disease based on outpatient clinics in township hospitals in rural Hongta District of Yunnan Province, China. METHODS: Fecal specimens of acute diarrhea cases and relevant epidemiological information were collected. Salmonella, Shigella, Vibrio, Aeromonas, Plesiomonas shigelloides and diarrheogenic Escherichia coli (DEC) were examined. RESULTS: Among the 797 stool specimens sampled, 198 samples (24...
March 5, 2018: International Journal of Infectious Diseases: IJID
Xiujuan Tang, Shisong Fang, Alice P Y Chiu, Qianying Lin, Edwin Yiu Nam Tang, Xin Wang, Daihai He
OBJECTIVE: This study aims to examine the synchrony of influenza epidemics between Hong Kong and Shenzhen, two neighboring subtropical cities in South China. METHODS: Laboratory-confirmed influenza data from January 2006 to December 2016 were obtained from the Shenzhen Center for Disease Control and Prevention and the Department of Health in Hong Kong. The population data were retrieved from the 2011 population censuses. The weekly rate of laboratory-confirmed influenza cases were compared between Shenzhen and Hong Kong...
March 3, 2018: International Journal of Infectious Diseases: IJID
Emma McGuire, Simon Tiberi, Holly Ciesielczuk, Mark Melzer
We present a rare case of Shigella flexneri bacteraemia and toxic megacolon, and discuss the challenges of conventional laboratory techniques versus molecular PCR platforms in differentiating between Shigella species and Escherichia coli.
March 1, 2018: International Journal of Infectious Diseases: IJID
Martin Rao, Davide Valentini, Alimuddin Zumla, Markus Maeurer
BACKGROUND: New tuberculosis (TB) drug treatment regimens are urgently needed. We evaluated the potential of the histone deacetylase inhibitors (HDIs) valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA) to enhance the effects of first-line TB drugs against intracellular Mycobacterium tuberculosis (M. tb). METHODS: M. tb H37Rv cultures were exposed to VPA or SAHA over six days, in the presence or absence of isoniazid (INH) and rifampicin (RIF). The efficacy of VPA and SAHA against intracellular M...
March 1, 2018: International Journal of Infectious Diseases: IJID
Wenjia Pearly Koh, Humaira Shafi
No abstract text is available yet for this article.
March 1, 2018: International Journal of Infectious Diseases: IJID
Alexandra Peters, Sarah Masson-Roy, Didier Pittet
No abstract text is available yet for this article.
February 28, 2018: International Journal of Infectious Diseases: IJID
Claudia Collu, Alessandro Fois, Paola Crivelli, Gianni Tidore, Claudio Fozza, Giovanni Sotgiu, Pietro Pirina
Clinical and radiological manifestations of tuberculosis (TB) are heterogeneous and differential diagnosis can include both benign and malignant diseases (e.g., sarcoidosis, metastatic diseases, and lymphoma). Diagnostic dilemmas can delay appropriate therapy, favoring Mycobacterium tuberculosis transmission.
February 22, 2018: International Journal of Infectious Diseases: IJID
Daniel B Chastain, Sarah Wheeler, Carlos Franco-Paredes, Babatunde Olubajo, W Anthony Hawkins
OBJECTIVE: The purpose of this study was to evaluate the use of empirical vancomycin for patients with neutropenic fever (NF) for adherence to treatment guidelines. METHODS: We identified adult patients with a diagnosis of neutropenia, who met the definition of NF as per treatment guidelines. Use of vancomycin was evaluated as part of empirical therapy and again, after 72hours. Outcomes were assessed using descriptive statistics, Chi square or Fisher's exact test, and univariate exact logistic regression analyses...
February 22, 2018: International Journal of Infectious Diseases: IJID
Rafael Aguiar Maciel, Helena Moreira Klück, Madeleine Durand, Eduardo Sprinz
OBJECTIVES: At present, limited data is available on comorbidity profiles associated to aging with HIV from the developing world, where most live. Our aim was to compare disease burden between older HIV-positive to HIV-negative matched controls in Brazil. METHODS: This was a cross sectional analysis of the South Brazilian HIV Cohort. Individuals aged 50 years or older were enrolled at Hospital de Clínicas de Porto Alegre and matched to HIV negative controls from the Primary Practice Unit of the same hospital...
February 21, 2018: International Journal of Infectious Diseases: IJID
Sandar Aye, Suman S Majumdar, Myo Minn Oo, Jaya Prasad Tripathy, S Satyanarayana, Nang Thu Thu Kyaw, Khine Wut Yee Kyaw, Nay Lynn Oo, Saw Thein, Myat Kyaw Thu, Kyaw Thu Soe, Si Thu Aung
OBJECTIVES: We assessed the effect of an active case finding (ACF) project on tuberculosis (TB) case notification and the yields from a household and neigbourhood intervention (screening contacts of historical index TB patients diagnosed >24months ago) and a community intervention (screening attendants of health education sessions/mobile clinics). DESIGN: Cross-sectional analysis of project records, township TB registers and annual TB reports. RESULTS: In the household and neigbourhood intervention, of 56,709 people screened, 1,076 were presumptive TB and 74 patients were treated for active TB with a screening yield of 0...
February 21, 2018: International Journal of Infectious Diseases: IJID
Anne Sofie Høgh Kølbæk Kjær, Thomas Aagaard Rasmussen, Niels Henrik Hjollund, Lotte Oerneborg Rodkjaer, Merete Storgaard
INTRODUCTION: Use of Patient-Reported Outcome (PRO) in outpatient care holds promise as a tool to enhance quality of care. The management of chronic HIV-infection is multidimensional, and clinical assessment includes broad screening to identify complications. With growing constraints on time and resources, the use of PROs may provide a much-needed tool to ensure optimal HIV-care. Here, we aimed to evaluate the clinical implementation and use of a web-based tool to collect PRO in a cohort of HIV-infected individuals...
February 21, 2018: International Journal of Infectious Diseases: IJID
Fred Bernardes Filho, Daiana Pess, Andressa Lumi Akabane, Norma Tiraboschi Foss, Marco Andrey Cipriani Frade
No Abstract.
February 21, 2018: International Journal of Infectious Diseases: IJID
Nese Saltoglu, Onder Ergonul, Necla Tulek, Mucahit Yemisen, Ayten Kadanali, Gul Karagoz, Ayse Batirel, Oznur Ak, Cagla Sonmezer, Haluk Eraksoy, Atahan Cagatay, Serkan Surme, Salih A Nemli, Tuna Demirdal, Omer Coskun, Derya Ozturk, Nurgul Ceran, Filiz Pehlivanoglu, Gonul Sengoz, Turan Aslan, Yasemin Akkoyunlu, Oral Oncul, Hakan Ay, Lutfiye Mulazımoglu, Buket Erturk, Fatma Yilmaz, Gulsen Yoruk, Nuray Uzun, Funda Simsek, Taner Yildirmak, Kadriye Kart Yaşar, Meral Sonmezoglu, Yasar Küçükardali, Nazan Tuna, Oguz Karabay, Nail Ozgunes, Fatma Sargın
OBJECTIVES: We described the clinical outcome of the diabetic patients who had foot infections with multidrug resistant organisms. METHODS: We included the patients with diabetic foot infections (DFI) from 19 centers, between May 2011 and December 2015. Infection was defined according to IDSA DFI guidelines. Patients with severe infection, complicated moderate infection were hospitalized. The patients were followed-up for 6 months after discharge. RESULTS: In total, 791 patients with DFI were included, 531(67%) was male, median age was 62 (19-90)...
February 21, 2018: International Journal of Infectious Diseases: IJID
Ali AlBarrak, Badriah Alotaibi, Yara Yassin, Abdulaziz Mushi, Fuad Maashi, Yassein Seedahmed, Mohamed Alshaer, Abdulaziz Altaweel, Husameddin Elshiekh, Abdulhafiz Turkistani, Tanaz Petigara, John Grabenstein, Saber Yezli
BACKGROUND: The Hajj mass gathering is a risk for pneumococcal disease. We evaluated the proportion of adult community-acquired pneumonia (CAP) cases attributable to Streptococcus pneumoniae among Hajj pilgrims in 2016. To add sensitivity to etiologic attribution, we used a urine-antigen test, in addition to culture-based methods METHODS: Adults hospitalized with x-ray confirmed CAP were prospectively enrolled from all general hospitals designated to treat Hajj pilgrims in the holy cities of Mecca and Medina...
February 20, 2018: International Journal of Infectious Diseases: IJID
Breno S Aguiar, Camila Lorenz, Flávia Virginio, Lincoln Suesdek, Francisco Chiaravalloti-Neto
OBJECTIVES: While Brazil has witnessed an unprecedented Zika (ZIK) epidemic, in recent times, Chikungunya (CHIK) has also come into prominence as a threat, in the Americas. We aimed to identify the regions with increased probabilities of ZIK and CHIK occurrence, based on environmental and social conditions. METHODS: To assess the potential spatial risk of ZIK and CHIK dissemination, we used a statistical Maxent model, which considered the number of probable autochthonous ZIK and CHIK cases, in 2015 and 2016, with environmental variables and social indicators...
February 14, 2018: International Journal of Infectious Diseases: IJID
Adnan Alatoom, Mohammad Sartawi, Karen Lawlor, Laila AbdelWareth, Jens Thomsen, Ahmad Nusair, Imran Mirza
In this case, we report an elderly patient with multiple chronic conditions and prolonged intensive care units (ICU) stay who had recurrent Candida auris (C. auris) in blood despite antifungal therapy. C. auris was misidentified using conventional automated identification system as Candida haemulonii resulting in delayed diagnosis. The isolate showed increasing minimum inhibitory concentrations (MICs) to different antifungal drugs and persisted in the patient's blood before the patient deceased. This is the first case of C...
February 13, 2018: International Journal of Infectious Diseases: IJID
F Del Bianco, M Morotti, M F Pedna, P Farabegoli, V Sambri
OBJECTIVES: To start a surveillance program to investigate the possible diffusion of mobilized colistin resistance genes in Enterobacteriaceae strains isolated in the Unit of Microbiology of the Great Romagna Hub Laboratory. METHODS: All the colistin resistant Enterobacteriaceae, isolated from August 1st 2016 to July 31st 2017, were prospectively evaluated for mcr-1 a mcr-2. Backdated survey of mcr-3, mcr-4 and mcr-5 was performed on the same group of isolates. Species identification was achieved by Vitek MS and the antibiotic susceptibility testing was performed both with Vitek-2 and Sensititre systems...
February 12, 2018: International Journal of Infectious Diseases: IJID
Armel M Sanou, Kenza Benkirane, Bachirou Tinto, Assana Cissé, Tani Sagna, Abdoul Kader Ilboudo, Claire Dording, Zekiba Tarnagda, Claude P Muller, Judith M Hübschen
OBJECTIVES: In this study, we monitored the seroprevalence of HBV-HDV co-infection in different population groups in the Western part of Burkina Faso, and described the genetic diversity of the detected virus strains. METHODS: Between October 2013 and December 2014, venous blood samples were collected from different cohorts (blood donors, pregnant women, outpatients) in the western region of Burkina Faso. Samples were tested for HBsAg and total anti-HDV antibodies...
February 9, 2018: International Journal of Infectious Diseases: IJID
Zil-E-Rubab, Saeeda Baig, Uzma Zaman, Mohammad Haris Lucky
AIM: To find out the association between Human Papilloma Virus (HPV) genotypes 16/18 in Pakistani patients with oral squamous cell carcinoma (OSCC). METHODS: DNA from oral rinse of 300 subjects (100 cases with OSCC and 200 controls(100 subjects with pre malignant oral lesions and 100 normal persons) were analyzed by both conventional and real time PCR using HPV consensus Gp5+/Gp6+ and HPV 16, 18 specific primers. RESULTS: Out of 300 persons, 74/300 (25%) were found to be infected with HPV: (46/100(46%) from cases and 74/200(14%) from controls...
February 9, 2018: International Journal of Infectious Diseases: IJID
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