Using Routine EMR Registration on a National Scale for Evaluating the Impact of HIV and ART on Childbirth in Burundi.

A number of international studies have reported that HIV+ mothers under ART on average deliver babies that have low birth weight (LBW), are smaller (LBH) and are more often premature [1,2,3,4,5,6,7,8,9]. These 3 elements are well known risk factors for neonatal mortality. In our study we wanted to assess the actual status of such supposed HIV and ART related neonatal mortality risks in Burundi by taking advantage of the country's large scale EMR implementation. A total of 64,682 birth records were extracted from EMRs in 17 hospitals for the period between January 1, 2018 and October 31, 2022. After quality control for missing or impossible data, 54,180 records were retained for the study. This study demonstrated that the use of ART during HIV+ pregnancies has no statistically significant impact on risk factors for neonatal mortality in Burundi. The study also indicates that the HIV prevalence among pregnant women in Burundi who give birth in a hospital is more than twice as high as expected based on the official figures. It was also demonstrated that an explanation for this finding cannot be found in a possible concentration of HIV+ deliveries in the hospital environment. The availability of large-scale implementation of structured electronic health records brings numerous new possibilities for population research based on routinely registered health data in a low-resource country like Burundi.