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Patient outcomes in longitudinal observational studies (POLOS) of rheumatoid arthritis: Determining the OMERACT core domain set.

Diego Benavent, Loreto Carmona, Maria A Lopez-Olivo, Catherine L Hill, Tiffany Westrich-Robertson, Niti Goel, Vibeke Strand, Beverley Shea, Shawna Grosskleg, Amye Leong, Catherine Hofstetter, Clifton Bingham, Daniel Meyer, Deb Constien, Dorthe B Berthelsen, Grayson Schultz, Ingrid de Groot, Joan Weiner, Kate Mather, Maarten de Wit, Peter Böhm, Sam Michel Cembalo, Peter Tugwell, Sebastian Bruera, Maria E Suarez-Almazor
Seminars in Arthritis and Rheumatism 2023 December 14
OBJECTIVE: To define and select rheumatoid arthritis (RA)-specific core domain set for Longitudinal Observational Studies (LOS) within the Outcome Measures in Rheumatology (OMERACT) framework.

METHODS: A three-round online Delphi exercise, including patient research partners (PRPs) and other community partners in healthcare, was conducted. Domains scored 7-9 (i.e., critically important to include) by ≥ 70 % of participants in both groups were included. Items were consolidated in a subsequent dedicated meeting.

RESULTS: Nineteen domains scored ≥ 70 % consensus in both groups. The focus group refined these into a list of twelve domains.

CONCLUSION: The achieved consensus will inform the next steps of developing the core domain set for LOS in RA.

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