Evidence of mechanisms in evidence-based policy.

Evidence-based policy has achieved great relevance in policy-making and social research. Nonetheless, over the past few years, several problematic aspects of this approach have been identified. This paper discusses whether, and to what extent, evidence of mechanisms could contribute to addressing certain difficulties faced by evidence-based policy. I argue that it could play a crucial role in the assessment of the efficacy of interventions, the extrapolation of interventions to target populations, and the identification of side effects. For analysing the potential contribution of evidence of mechanisms, the previous debate on the pluralist approach to evidence-based medicine is taken as reference.