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Pediatric COMBINED LIVING DONOR LIVER AND KIDNEY TRANSPLANTATION FOR Primary Hyperoxaluria Type II.
American Journal of Transplantation 2023 May 14
We report the case of a 12-year-old boy with Primary Hyperoxaluria Type 2 (PH2) presenting with end-stage renal disease and systemic oxalosis who underwent combined living donor liver and kidney transplant from two donors- one of whom was heterozygous carrier of the mutation. Plasma oxalate and creatinine levels normalized immediately following the transplant and remain normal after 18 months. We recommend combined liver and kidney transplantation as the preferred therapeutic option for children with PH2 with early onset end stage renal disease.
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