Review of the literature of the efficacy and safety of a new cosmetic topical treatment containing Pistacia lentiscus and hyaluronic acid for the treatment of nail plate damages.

OBJECTIVES: The objective of or study is the review of the literature about efficacy and safety of a novel water-soluble nail strengthened (WSNS) containing hyaluronic acid and Pistacia lentiscus used for the improvement of nail plate diseases.

MATERIALS AND METHODS: We conducted literature research of PubMed/MEDLINE to identify all the studies reporting the use of hyaluronic acid and Pistacia lentiscus in the improvements of nail alterations.

RESULTS: We found 2 reports and 2 posters published in literature, accounting for 96 patients treated with WSNS containing Pistacia lentiscus and hyaluronic acid. 83 patients were affected by brittle nails and 13 patients by onychomycosis.

CONCLUSIONS: This review demonstrates that the daily application of this new product containing Pistacia lentiscus and hyaluronic acid can be used as cosmetic adjuvant for improving common nail diseases such as nail fragility and onychomycosis, with significant results on nail quality and appearance. Patients did not report any adverse event, and its ease of application and cosmetic qualities contribute to the great compliance to treatment.