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Journal of Cosmetic Dermatology

Hyeon Yong Lee
BACKGROUND: The development of an alternative medicine to treat atopic dermatitis (AD) from natural sources is necessary. AIMS: To improve skin barrier dysfunction by enhancing the differentiation of human keratinocytes with the fermented Scutellaria baicalensis. METHODS: Scutellaria baicalensis was fermented with Lactobacillus plantarum and extracted with 70% ethanol (FE). Antioxidant activities and the regulation of the gene expression related to keratinocyte differentiation were measured as well as its proliferation...
March 15, 2018: Journal of Cosmetic Dermatology
Firas Al Qarqaz, Ali Al-Yousef
BACKGROUND: Acne is very common skin condition. Most patients with acne will have a degree of scarring as a result of their acne. In patients with darker skin color the scarring can be further complicated by hyperpigmentation. Several treatment options can be used to improve acne scarring, however the problem of post acne hyperpigmentation is not often addressed. This study especially focus on the treatment of pigmented post acne scarring using skin microneedling. AIMS: The primary objective is to assess the improvement of pigmentation of acne scarring in patients with dark skin using microneedling...
March 15, 2018: Journal of Cosmetic Dermatology
Mary Mina, Lamia Elgarhy, Hanan Al-Saeid, Zeinab Ibrahim
BACKGROUND: Several treatment modalities had been used for the treatment of vitiligo, but the optimal treatment has not yet been identified. OBJECTIVES: To study the efficacy of microneedling with 5-flurouracil vs its efficacy with tacrolimus in the treatment of vitiligo. PATIENTS AND METHODS: Twenty-five patients with vitiligo were subjected to microneedling of 2 patches of vitiligo with dermapen, then application of 5-fluorouracil to 1 patch and tacrolimus on the other patch...
March 12, 2018: Journal of Cosmetic Dermatology
Michael Gold, Anneke Andriessen, Alexandros Bader, Red Alinsod, Elizabeth Shane French, Nathan Guerette, Yegor Kolodchenko, Michael Krychman, Susan Murrmann, Julene Samuels
INTRODUCTION: The use of energy-based devices for the treatment of vaginal laxity, orgasmic dysfunction, and stress incontinence, such as minimally ablative fractional laser and radiofrequency, is gaining momentum. This review aims to answer clinical questions on the application of energy-based devices for feminine genital rejuvenation. METHODS: The target group includes physicians involved in esthetic medicine and feminine genital rejuvenation. A literature review was conducted on technologies in use for feminine rejuvenation to explore their safety, efficacy, tolerability, patient satisfaction, and clinical usability...
March 10, 2018: Journal of Cosmetic Dermatology
Hassan Ibrahim, Moustafa El Taieb, Zeinab El Gamel, Abdel Rahman El Saied
BACKGROUND: Narrow-band ultraviolet B (NB-UVB) is the gold standard in the treatment of vitiligo. 25-hydroxyvitamin D (25-OH- vitamin D) might play a physiological role in photo-induced melanogenesis in human skin so the association between vitamin D levels and vitiligo still needs to be investigated more thoroughly. OBJECTIVE: we aim to investigate the influence of cumulative doses of NB-UVB phototherapy on vitamin D in patients with vitiligo and their correlation with NB-UVB-induced pigmentation...
March 10, 2018: Journal of Cosmetic Dermatology
Klaus Fritz, Carmen Salavastru, Magdalina Gyurova
INTRODUCTION: This study investigates noninvasive cellulite treatments based on simultaneous application of monopolar radiofrequency (RF) and targeted pressure energy to evaluate efficacy and safety and to see whether simultaneous application has any benefits in noninvasive cellulite treatments. METHODS: Thirty women with cellulite (fibrous/adipose/aqueous types) received 4 gluteofemoral treatments (~24 minutes; ~1000 cm2 ) using a simultaneous application of RF and targeted pressure energy...
March 9, 2018: Journal of Cosmetic Dermatology
Jongmi Lim, Chae Jin Lim, Sungwoo Kim, Gaewon Nam, Minyoul Chang, Keedon Park, Kyungho Park, Hyun Jung Kim, Jeong Keun Ahn, Sekyoo Jeong
BACKGROUND: Recently, potential roles of autophagy in skin homeostasis received many interests. But, little has been reported for the potential antiaging effects of autophagy activator. OBJECTIVE: With the newly synthesized autophagy activator, heptasodium hexacarboxymethyl dipeptide-12 (Aquatide™) in vitro and clinical efficacy of the topical autophagy activator as an antiaging cosmeceutical ingredient was evaluated. METHODS: Antioxidant effect of Aquatide™ was evaluated by radical scavenging assay...
March 9, 2018: Journal of Cosmetic Dermatology
Mehdi Gheisari, Behzad Iranmanesh, Bita Saghi
BACKGROUND AND AIM: A comprehensive study comparing two different modalities, Nokor needle subcision (NNS) and blunt cannula subcision (BCS), for treatment of acne scars, has not been reported previously. The aim was to compare the effectiveness of these two methods based on patient's and doctor's satisfaction measures, in addition to the late complications 3 months postsubcision. METHOD OF INTERVENTION: Patients had 18-65 years old, with acne scars on both malar sides...
March 9, 2018: Journal of Cosmetic Dermatology
Jordan V Wang, Christopher B Zachary, Nazanin Saedi
This study addresses the dilemma concerned with meeting patients who may have encountered counterfeit esthetic devices in the marketplace. Over the past several years, we have witnessed a rise in counterfeit injectables and medical devices in our field. Often times, the procedures are marketed to patients at significantly reduced prices compared to competitors. Patients may be unaware that counterfeit devices exist and may unknowingly have procedures completed using untested and uncertified devices. It is important for clinicians to recognize when their patients may be encountering counterfeit devices, know what to do in this situation, and offer the best recommendations...
March 8, 2018: Journal of Cosmetic Dermatology
Peter Hsien-Li Peng, Jui-Hui Peng
INTRODUCTION: The tear trough deformity is commonly requested for correction, most often by filler injections. However, the tear trough remains difficult to treat due to its complex anatomy, a variety of other concurrent deformities, and the high risk of complications. OBJECTIVES: To create a standardized categorization, evaluation, and treatment protocol for the management of tear troughs with fillers. METHODS: (1) Patient deformity profiles are determined using three categories of traits: A (Atrophy), B (Bulging), L (Laxity)...
March 5, 2018: Journal of Cosmetic Dermatology
Jizhen Ren, Sumei Liu, Jin'e Wan, Enhao Kang, Zhenyu Chen
OBJECTIVE: To explore the influence of hyperbaric oxygen on scar formation in rabbit ears. METHODS: A total of 20 New Zealand rabbits were selected to establish the hypertrophic scar model on the ears. The rabbits were randomly divided into control group and experimental group (7d, 14d, 21d, and 28d group according to different HBO treatment days),each experimental group received hyperbaric oxygen treatment after the operation at the same time everyday for 1 hour...
March 4, 2018: Journal of Cosmetic Dermatology
Mohammad-Reza Mahmoudian-Sani, Fatemeh Rafeei, Razieh Amini, Massoud Saidijam
INTRODUCTION: Mesenchymal stem cells (MSCs) are multipotent stem cells that have the potential of proliferation, high self-renewal, and the potential of multilineage differentiation. The differentiation potential of the MSCs in vivo and in vitro has caused these cells to be regarded as potentially appropriate tools for wound healing. After the burn, trauma or removal of the tumor of wide wounds is developed. Although standard treatment for skin wounds is primary healing or skin grafting, they are not always practical mainly because of limited autologous skin grafting...
March 4, 2018: Journal of Cosmetic Dermatology
Sushama Sushama, Niharika Dixit, Ram Krishna Gautam, Pooja Arora, Ananta Khurana, Anubhuti Anubhuti
BACKGROUND: Vitiligo is an autoimmune disease associated with alteration in levels of various cytokines. However, there are very few studies in this regard. OBJECTIVES: To assess the serum levels of cytokines secreted by Th1 (IL-2, TNF-α), Th2 (IL-6), and Th17 cells (IL-17, IL-22) in patients with localized vitiligo and generalized vitiligo and to correlate their levels with the extent, duration, and activity of disease. MATERIAL AND METHODS: Sixty patients of vitiligo (30 each of localized and generalized) and 30 controls were recruited in the study...
March 4, 2018: Journal of Cosmetic Dermatology
Alan D Widgerow, Lily I Jiang, Antoanella Calame
INTRODUCTION: An antiaging regimen that aids in clearing the matrix of waste products and stimulating neocollagenesis and neoelastogenesis was tested among a group of subjects over the course of 12 weeks to assess its efficacy in women with mild to moderate wrinkles and skin sagging on the face. MATERIALS AND METHODS: The efficacy of the product regimen was tested in 22 subjects using investigator clinical grading measurements, raking light imaging, 3D imaging, biopsies, and self-assessment questionnaires at baseline and weeks 4, 8, and 12...
March 4, 2018: Journal of Cosmetic Dermatology
Anna Kasielska-Trojan, Michał Pietrusiński, Maciej Borowiec, Bogusław Antoszewski
BACKGROUND: Striae have been reported to be one of the most common skin lesions and a commonly encountered esthetic problem. OBJECTIVES: The aim of this research was to examine elastin gene polymorphism (rs7787362, ELN) and collagen type III alpha 1 polymorphism (rs1800255, COL3A1) among polish woman population with SD in comparison with women without the lesions and to verify these polymorphisms as risk factors for SD. METHODS: Seventy female students (35 with striae (the mean age 23...
March 1, 2018: Journal of Cosmetic Dermatology
Adel A Ibrahim, Rehab M Salem, Ola S El-Shimi, Shaymaa M A Baghdady, Shimaa Hussein
BACKGROUND: Despite the several studies suggesting the genetic basis of acne vulgaris, the exact genetic architecture of this very common condition is not yet clear. AIM OF THE WORK: This study aimed to investigate the association between IL-1A (-889) gene polymorphism and acne vulgaris in a sample of patients. SUBJECTS AND METHOD: Blood samples from 100 patients with acne vulgaris and 100 healthy age, sex, and BMI matched controls were obtained...
March 1, 2018: Journal of Cosmetic Dermatology
Adone Baroni
Xanthelasma palpebrarum is the most common type of xanthoma affecting the eyelids. It is characterized by asymptomatic soft yellowish macules, papules, or plaques over the upper and lower eyelids. Many treatments are available for management of xanthelasma palpebrarum, the most commonly used include surgical excision, ablative CO2 or erbium lasers, nonablative Q-switched Nd:YAG laser, trichloroacetic acid peeling, and radiofrequency ablation. This study aims to evaluate the effectiveness of RF ablation in the treatment of xanthelasma palpebrarum, with D...
March 1, 2018: Journal of Cosmetic Dermatology
Yusha Zi, Bo Zhang, Biao Jiang, Xingyao Yang, Zilu Liang, Weiyi Liu, Congfen He, Lei Liu
BACKGROUND: Lentinus edodes is one of the largest edible fungi. Lentinan, extracted from its fruiting body has clinically significant anticancer, antibacterial, antiviral, and anticoagulant effects; however, its preventive effects on skin oxidative damage are unclear. AIMS: We aimed to evaluate the in vitro antioxidation capability of lentinan and its protective and reparative effects on a model of cell oxidative damage. METHODS: We evaluated the in vitro antioxidant potential of lentinan by assessing its free-radical quenching ability using DPPH and ABTS and superoxide anions...
February 23, 2018: Journal of Cosmetic Dermatology
Muhammad Ahmad
OBJECTIVES: To measure the effects of platelet-rich plasma (PRP) on hair diameter in Pakistani population. MATERIALS AND METHODS: The study was conducted in a private setup in the adult patients undergoing PRP treatment. Baseline platelets count was noted for each patient. PRP was prepared using a commercial kit. Three PRP injections were administered in the scalp at 0, 1, and 3 months of interval. The hair caliber was measured in the mid-scalp area using a separate stencil for each patient...
February 23, 2018: Journal of Cosmetic Dermatology
Noha Nabil Doghaim, Rania Ahmed El-Tatawy, Yomna Mazid El-Hamd Neinaa, Marwa Mohsen Abd El-Samd
BACKGROUND: Management of alopecia areata (AA) and androgenetic alopecia (AGA) is often challenging. The use of carboxytherapy may be a novel therapeutic option for such cases. OBJECTIVE: To evaluate the clinical efficacy and safety of carboxytherapy in alopecia areata and androgenetic alopecia. PATIENTS AND METHODS: This study was conducted on 80 patients with alopecia divided into two groups; Group I included 40 AA patients (Group IA received carboxytherapy and Group IB control received placebo), and Group II included 40 AGA patients (Group IIA received carboxytherapy and Group IIB control received placebo), and followed up monthly for 3 months...
February 20, 2018: Journal of Cosmetic Dermatology
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