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Journal of Cosmetic Dermatology

Amany I Mustafa, Ola S El-Shimi
BACKGROUND: Acne vulgaris is a common chronic inflammatory skin disease involving pilosebaceous units. Adipokines are secreted by adipose tissue and function as signaling networks communicating it with different organs. They may have role in pathogenesis of acne vulgaris and the associated insulin resistance. Irisin, a hormone like myokine, is one of adipokines with anti-inflammatory, anti-oxidant, and anti-diabetic effects. AIMS: We aimed at evaluation of serum irisin level in patients with acne vulgaris to assess its correlation with disease pathogenesis...
September 20, 2018: Journal of Cosmetic Dermatology
Isha Narang, Kabir Sardana, Ram Bajpai, Vijay K Garg
BACKGROUND: Effect of seasonality on acne and acne flare has varied interpretations depending on the geographical area of study. In tropical areas, factors like high temperature and humidity may cause acne flares. AIMS: To assess the seasonal variation of acne in patients and to correlate it with the monthly temperature and humidity over a period of 1 year. METHODS: A cross-sectional study of acne patients was conducted for one year. The patient's acne was graded...
September 20, 2018: Journal of Cosmetic Dermatology
Ronald Bush, Peggy Bush
BACKGROUND: Heat modalities are commonly used as either primary or adjunctive treatment for telangiectasia. Minimal information is available as to the nature of injury to the vessel and surrounding tissue. METHOD: A total of 135 patients were treated over a 2-year period using ohmic thermolysis (45), 940 nm laser (50), and 940 nm laser with sclerotherapy (40). After treatment, 1 mm biopsies were done in selected patients in each group. Clinical correlation was studied in each group by observing vessel response at 4-6 weeks postprocedure...
September 17, 2018: Journal of Cosmetic Dermatology
Carolyn I Jacob, Katya Paskova
BACKGROUND: Thermal fat reduction technologies are leading the market for nonsurgical abdominal contouring. However, they are ideal principally for patients with fat bulges. OBJECTIVES: Our study investigates the effects of a novel nonthermal technology affecting the abdominal musculature and subcutaneous adipose tissue. MATERIALS AND METHODS: A total of 22 patients (avg. BMI 23.8 kg m-2 ) underwent 4 treatments on abdomen with high-intensity focused electromagnetic (HIFEM) field device...
September 17, 2018: Journal of Cosmetic Dermatology
Ana Luísa Vale, Ana Sofia Pereira, Andreia Morais, Andreia Noites, Adriana Clemente Mendonça, Juliana Martins Pinto, Rui Vilarinho, Paulo Carvalho
BACKGROUND: Equipment that acts in the reduction in adipose tissue are becoming widely investigated. One of the resources that begin to gain recognition is radiofrequency. PURPOSE: To verify the existence of scientific evidence and the methodological quality of the articles on the effects of radiofrequency in the reduction in adipose tissue. METHODOLOGY: Systematic review with meta-analysis on the effects of radiofrequency on adipose tissue...
September 17, 2018: Journal of Cosmetic Dermatology
Aimee E Krausz, David J Goldberg, David H Ciocon, Adam J Tinklepaugh
BACKGROUND: Rhinophyma is a cosmetically deforming disease characterized by nodular overgrowth of the lower 2/3 of the nose and is considered the end stage of acne rosacea. AIMS: Review the spectrum of procedural techniques for treatment of rhinophyma with a focus on the advantages and disadvantages of each modality. METHODS: A comprehensive literature search was conducted using the search terms "rhinophyma," "treatment," and "surgery" in PubMed...
September 17, 2018: Journal of Cosmetic Dermatology
Hyuck Hoon Kwon, Sun Chul Choi, Jae Yoon Jung, You In Bae, Gyeong-Hun Park
BACKGROUND: Although a 1450-nm diode laser has been shown to be effective for acne, the conventional high-energy stamp-only regimen is often associated with pain and hyperpigmentation, especially for dark-skinned individuals. AIMS: To evaluate whether the novel dual regimen has clinical advantages for acne treatments compared with conventional regimen in Asian patients. PATIENTS AND METHODS: Twenty-four Korean patients with facial acne were treated with a 1450-nm diode laser through a 20-week, randomized, split-face study...
September 17, 2018: Journal of Cosmetic Dermatology
Sławomir Wilczyński, Anna Stolecka-Warzecha, Anna Deda, Robert Koprowski, Karolina Flasz, Bartosz Błoński, Małgorzata Musioł
In recent years, popularity of radiofrequency (RF) has increased significantly. They are characterized by a low risk of complications and relatively high effectiveness. RF use high-frequency currents causing oscillating motion of ions resulting in temperature rise stimulating skin regeneration processes. The aim of this work was the thermographic evaluation of the skin exposed to RF of different intensity. The dynamic thermal imaging was used to study the temperature of the skin exposed to RF. The research was carried out in two locations with different adipose tissue content: abdomen (ROI1) and forearm (ROI2)...
September 17, 2018: Journal of Cosmetic Dermatology
Mervat M Swelam, Rasha A H El-Barbary, Wael M Saudi, Marwa S Fathi, Dina A Soliman, Heba H Abd Elrehem
BACKGROUND: Acne vulgaris (AV) pathogenesis is multifactorial. Vitamin D (VitD) plays an important role in sebocytes' differentiation and function. Most VitD functions are mediated by the nuclear VitD receptor (VDR) following binding of its biologically active form (1,25 dihydroxyvitamin D3). Genetic variations in VDR gene may cause significant receptor dysfunction and have been found to be associated with many inflammatory skin diseases. Two adjacent single nucleotide polymorphisms of VDR, ApaI (rs7975232) and TaqI (rs731236), were commonly studied...
September 15, 2018: Journal of Cosmetic Dermatology
Hung-Hsu Yang, Yong Miao, Yu-Tsung Chen, Zhi-Qi Hu
BACKGROUND: Minimally invasive techniques, including superficial liposuction with automatic shaver curettage (LC), subcutaneous laser treatment, and microwave-based therapy have been developed to treat osmidrosis. Few studies have compared these three techniques in relation to clinical efficacy, life quality improvement, and downtime. AIMS: We aim to evaluate clinical results and life quality improvement, in addition to downtime and complications, between these three techniques...
September 10, 2018: Journal of Cosmetic Dermatology
Sylvie Boisnic, Marie-Christine Branchet, Christelle Gouhier-Kodas, François Verriere, Violaine Jabbour
BACKGROUND: Diosmin, a naturally occurring flavonoid, is considered as a vascular-protective agent and is used orally to treat chronic venous insufficiency. It exhibits anti-inflammatory and free radical scavenging properties, but, like many other flavonoids, it is poorly absorbed in the small intestine. OBJECTIVE: Our aim was to investigate the skin protective effects of a diosmin-based cream, using skin organ culture as model. METHODS: Fragments of human skin explants, cultured ex vivo, were allocated to four treatment groups: no cream, no cream + stress, placebo cream + stress, and 2% diosmin cream + stress...
September 10, 2018: Journal of Cosmetic Dermatology
Rungsima Wanitphakdeedecha, Chanida Ungaksornpairote, Arisa Kaewkes, Angkana Sathaworawong, Bavornrat Vanadurongwan, Nittaya Lektrakul
BACKGROUND: Enlarged, hypertrophy calf muscles are common in Asian women and can cause psychological burden. Botulinum toxin A (BTA) has been widely used in treating masseteric muscle hypertrophy and it's efficacious as a noninvasive method for calf-contouring has been reported. Food and Drug Administration has approved onabotulinumtoxin A (ONA, Botox; Allergan Inc, Irvine, CA, USA) for upper face rejuvenation and it has off-label uses for calf-contouring. A recently introduced Prabotulinumtoxin A (NABOTA® , PRA; Daewoong Pharmaceutical, Seoul, Korea) demonstrated a comparable efficacy and safety to ONA for masseter reduction...
September 10, 2018: Journal of Cosmetic Dermatology
Kakul Husain
BACKGROUND: The harmful health effects of personal care products especially cosmetics have engulfed many societies of the world especially the female section without an alarm. OBJECTIVES: To estimate the prevalence of cosmetic usage and to assess the experiences of Saudi female undergraduate students in Wadi Al Dawasir province in an attempt to arouse general awareness among Saudi students about the harmful effects of the chemicals present therein. METHODOLOGY: It is a cross-sectional study carried out with a total of randomly selected 106 college students (female) at undergraduate level...
September 10, 2018: Journal of Cosmetic Dermatology
Eman Nofal, Ahmad Nofal, Khalid Gharib, Mohammad Nasr, Ahmed Abdelshafy, Eman Elsaid
BACKGROUND: Successful management of acne involves choosing proper medication. Chemical peeling is a well-known option in treatment of acne vulgaris. OBJECTIVE: To evaluate and compare the clinical efficacy and safety of combination chemical peels vs single peel in treatment of mild-to-moderate acne. METHODS: The study included 45 patients with mild-to-moderate acne divided into three equal groups. Group A underwent combination sequential peels with modified Jessner's solution (MJ) followed by trichloro acetic acid (TCA20%) on the right (Rt) side of the face vs TCA 30% on the left (Lt) side...
September 10, 2018: Journal of Cosmetic Dermatology
Marie-Dominique Thouvenin, Adeline Bacquey, Thérèse Nocera, Ana Beatris Rossi
BACKGROUND: Emollients are recommended for managing chronic hand dermatitis (CHD). Medical device repairing emollient creams (MDRECs) are suitable for treating CHD-associated skin lesions, unlike most cosmetic emollient products that can only be used on healthy skin. OBJECTIVES: The aim of this study was to examine the tolerability and benefit of a MDREC, Dexyane MeD® , in adults with CHD. METHODS: In an open-label study, adults aged 18-65 years with mild-to-moderate CHD were instructed to apply the MDREC on both hands twice daily for 3 weeks...
September 8, 2018: Journal of Cosmetic Dermatology
Elena Fedyakova, Ander Pino, Lidiya Kogan, Charusa Eganova, María Troya, Eduardo Anitua
BACKGROUND: The aging process affects all organs of the body, but the skin is the most visible indicator with a great psychosocial impact. As a consequence, many skin anti-aging strategies have been developed to minimize, postpone, and even reverse the aging process. Growth factors have been widely studied in skin wound healing as these polypeptides play an essential role in the complex process of tissue regeneration. Recently, a novel 3D injectable gel based on the autologous technology platelet rich in growth factor has been described...
September 8, 2018: Journal of Cosmetic Dermatology
Shweta Shetty, Jobin Jose, Lalit Kumar, R Narayana Charyulu
BACKGROUND: Dual-release mechanism of ethosomal gels (ie, ethosomes and gel) makes them as versatile drug delivery systems for topical applications. Clove oil is obtained from the clove buds exhibited broad antifungal and antibacterial activity. Cutaneous candidiasis is the infection caused by Candida albicans or other Candida species. AIM: The aim of the present study was to prepare ethosomal gel of clove oil and evaluate its effectiveness in the treatment of cutaneous candidiasis...
August 31, 2018: Journal of Cosmetic Dermatology
Marcelo Pompeu, Vanessa Lima, Hugo Leornardo Magalhaes, Neysa Regattieri, Izelda Maria Carvalho Costa
Intralesional corticoid infiltration guided by 22-MHz ultrasound is a new, noninvasive, and safe dermatological method for the treatment of foreign body granuloma. The great advantage of the procedure is that the medication is delivered straight to the desired target, preventing adverse treatment effects in noninjured areas.
August 29, 2018: Journal of Cosmetic Dermatology
Huisuk Yang, Suyong Kim, Mingyu Jang, Hyeonjun Kim, Seunghee Lee, Youseong Kim, Younghyon Andrew Eom, Geonwoo Kang, Liching Chiang, Ji Hwoon Baek, Ja Hyun Ryu, Ye Eun Lee, Jaesuk Koh, Hyungil Jung
BACKGROUND: Dissolving microneedles (DMNs) have been used for skin restoration and wrinkle improvement. Although lipophilic compounds, for example, natural oils or ceramides, enrich the skin barrier, their delivery via DMNs is challenging because of DMN fabrication difficulties. OBJECTIVES: In the present study, we combined a topical formulation and a DMN patch to perform two-phase delivery comprising a lipophilic formulation and hydrophilic compound-loaded DMNs to improve skin barrier status and the efficacy of drug delivery...
August 29, 2018: Journal of Cosmetic Dermatology
Xiaoyuan Xie, Yaning Wang, Qingting Zeng, Ying Lv, Rong Hu, Ke Zhu, Chen Liu, Wei Lai, Lei Guan
INTRODUCTION: Neck skin aging is of particular interest to skin scientists and dermatologists because of the increasing demand for neck wrinkle improvement. This study aimed to determine the neck aging features of Chinese women and to investigate the clinical alterations and mechanical, topographical, and biophysical properties of neck skin. METHODS: A total of 450 Chinese women (age range: 16-66 years) were clinically examined and graded by the same dermatologist using standardized photographs...
August 29, 2018: Journal of Cosmetic Dermatology
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