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Journal of Cosmetic Dermatology

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https://www.readbyqxmd.com/read/28639749/evaluation-of-the-in%C3%A2-vivo-cosmetic-efficacy-of-the-mfiii-blue-cell-serum-gel-one-and-two-month-test-results
#1
Dina Tukhvatullina, Alain Béguin, Henry Pong, Maria Del Mar Cabarbas, Dmitry Klokol, Mike Ks Chan, Michelle B F Wong
INTRODUCTION: Skin is changing over time showing signs of aging: dryness, increase in visual and tactile roughness, decrease in collagen content and stiffness, and eventually formation of deep and surface wrinkles, and fine lines. METHODS: Eight-week open experimental study was conducted to test efficacy of MFIII Blue Cell Serum Gel. Main criteria to determine product efficacy by following skin biophysical techniques were as follows: skin moisturization, firmness, epidermal and dermal density, skin surface properties and sebum level, reduction in fine lines and wrinkles...
June 22, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28631890/oxidative-stress-and-psychiatric-morbidity-in-patients-with-facial-acne
#2
Sara M Awad, Hanan Morsy, Ayat A Sayed, Nahed A Mohamed, Ghada M Ezzat, Mostafa M Noaman
BACKGROUND: Acne vulgaris is a common cosmetic problem that is frequently associated with psychosocial disturbances as well as increased oxidative stress. However, oxidative stress and psychological aspects have been studied separately in acne. OBJECTIVE: To evaluate the relationships between oxidative stress, anxiety, depression, and quality of life in acne patients. METHODS: Sixty patients with facial acne and 40 age- and sex-matched healthy individuals were included in the study...
June 20, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28594082/acneiform-eruptions-caused-by-vitamin-b12-a-report-of-five-cases-and-review-of-the-literature
#3
Stefano Veraldi, Susanna Benardon, Marco Diani, Mauro Barbareschi
We describe five cases of acneiform eruption caused by vitamin B12 in five females aged 37, 32, 62, 29, and 21 years, respectively. The eruption appeared from 1 week to 5 months after the beginning of the therapy with i.m. or oral vitamin B12. Clinical picture was characterized by papules and pustules located on the face. In three patients, similar lesions were also present on the neck, shoulders, chest, and upper portion of the back. Comedones and cysts were absent. In two patients, serum vitamin B12 levels were very high...
June 8, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28593645/ultraviolet-a-photosensitivity-profile-of-dexchlorpheniramine-maleate-and-promethazine-based-creams-anti-inflammatory-antihistaminic-and-skin-barrier-protection-properties
#4
Gustavo Facchini, Samara Eberlin, Stefano Piatto Clerici, Ana Lucia Tabarini Alves Pinheiro, Adilson Costa
BACKGROUND: Unwanted side effects such as dryness, hypersensitivity, and cutaneous photosensitivity are challenge for adherence and therapeutical success for patients using treatments for inflammatory and allergic skin response. AIMS: In this study, we compared the effects of two dermatological formulations, which are used in inflammatory and/or allergic skin conditions: dexchlorpheniramine maleate (DCP; 10 mg/g) and promethazine (PTZ; 20 mg/g). METHODS: We evaluated both formulations for phototoxicity potential, skin irritation, anti-inflammatory and antihistaminic abilities, and skin barrier repair in vitro and ex vivo using the standard OECD test guideline n° 432, the ECVAM protocol n° 78, and cultured skin explants from a healthy patient...
June 7, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28589618/comparison-of-different-regimens-of-pimecrolimus-1-cream-in-the-treatment-of-facial-seborrheic-dermatitis
#5
Juemin Zhao, Wenjia Sun, Chengfeng Zhang, Jiaqiang Wu, Yan Le, Chunyun Huang, Ye Liu, Leihong Xiang
BACKGROUND: Pimecrolimus 1% cream has already been proved to be an effective and safe alternative to treat seborrheic dermatitis. However, the treatment periods were inconstant in previous studies. OBJECTIVE: To evaluate the comparative efficacy of pimecrolimus 1% cream with different regimens for the treatment of facial seborrheic dermatitis. METHOD: Thirty patients with facial seborrheic dermatitis were enrolled and randomly distributed to three groups...
June 7, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28574197/cross-sectional-study-of-the-microbiological-safety-profile-of-reusing-hyaluronic-acid-fillers
#6
Rubens Pontello, Rogério Nabor Kondo, Priscila Daiane Pavezzi, Theo Nicolacopulos, Julia Pagung Kippert, Clarissa Lena
INTRODUCTION: Facial filling with hyaluronic acid (HA) is a dermatological procedure that has been emerging today. There are not many references regarding safety of reusing the remaining product for later touch-up in the same patient. OBJECTIVE: To determine the microbiological safety of reusing hyaluronic acid that is remnant from syringes used for facial filling, stored at room temperature or cooled in a refrigerator at 4°C. MATERIALS AND METHODS: In culture medium, small aliquots of leftovers from 31 hyaluronic acid fillers, previously used for facial filling, were inoculated...
June 2, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28574158/efficacy-and-safety-of-a-new-microneedle-patch-for-skin-brightening-a-randomized-split-face-single-blind-study
#7
Kui Young Park, Hyun Jung Kwon, Changjin Lee, Daegun Kim, Jun Jin Yoon, Myeong Nam Kim, Beom Joon Kim
BACKGROUND: Although microneedles are one of the best transdermal drug delivery systems for active compounds, few clinical trials have examined the safety and efficacy of brightening microneedle patches. AIMS: To determine the efficacy and safety of a newly developed whitening microneedle patch. PATIENTS/METHODS: A split-face study was designed for efficacy assessment with 34 Korean women applying the tested product (a whitening microneedle patch) on one cheek and a control whitening essence on the other...
June 2, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28568892/patch-testing-in-patients-with-suspected-cosmetic-dermatitis-a-retrospective-study
#8
Taru Garg, Soumya Agarwal, Ram Chander, Aashim Singh, Pravesh Yadav
BACKGROUND: Growing use of cosmetics has led to an increase in the incidence of allergic contact dermatitis (ACD) to cosmetics. Patch testing helps to confirm allergy to cosmetics and pinpoint the exact offending allergens. AIMS AND OBJECTIVES: The study aimed to find the frequency of positive patch test reactions in cases with suspected ACD to cosmetics, and the common allergens responsible for it. METHODS: This is a retrospective record-based study of 58 patients, with suspected ACD to cosmetics, who had undergone patch testing with Indian standard series and Indian cosmetic and fragrance series from January 2013 to December 2015...
June 1, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28556423/a-rare-complication-of-topical-atropine-for-treatment-of-eccrine-hidrocystoma-pharmacological-fixed-dilated-pupils
#9
Alireza Zandi, Bahareh Abtahi-Naeini, Mohsen Pourazizi
Multiple eccrine hidrocystoma (EH) has been treated with topical atropine with variable results. However, in rare cases, anticholinergic side effects have been seen after the use of the topical form of this drug. We presented a 50-year-old woman who developed recent onset of visual disturbance and photophobia from 2 weeks prior. The diagnosis of topical atropine-induced bilateral mydriasis was made. We reported a recognized but often overlooked case of bilateral mydriasis caused by application of topical 1% atropine for treatment of multiple EH...
May 29, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28556393/evaluation-of-the-safety-and-efficacy-of-a-monopolar-nonablative-radiofrequency-device-for-the-improvement-of-vulvo-vaginal-laxity-and-urinary-incontinence
#10
Shelena Lalji, Paula Lozanova
BACKGROUND AND OBJECTIVE: Vaginal childbirth, natural process of aging, congenital factors, and surgical interventions are considered the main causes of vulvo-vaginal laxity driven by changes in collagen and elastin fibers. This causes a loss of strength and flexibility within the vaginal wall. As a result, women may experience lack of sensation and stress urinary incontinence (SUI)-the condition of involuntary loss of urine associated with activities that cause an increase in intra-abdominal pressure (eg, sneezing, coughing, and lifting)...
May 29, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28556292/a-review-of-the-role-of-sebum-in-the-mechanism-of-acne-pathogenesis
#11
REVIEW
Xinchao Li, Congfen He, Zhou Chen, Cheng Zhou, Yao Gan, Yan Jia
Acne is one of the most common skin disorders, and its occurrence is closely related to many factors, including sebum secretion, hormone levels, bacterial infection, and inflammatory reactions. Among these, changes in sebum secretion are believed to be one important factor of acne. Increased sebum secretion can induce acne occurrence, and increasing evidence indicates sebum component changes are also strongly related to acne occurrence. Recently, developments in lipidomics have provided effective lipid analysis methods...
May 29, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28544730/human-skin-gene-expression-doesn-t-correlate-with-protein-expression-unless-both-parameters-are-quantified
#12
Edwin D Lephart
Many cosmetic companies utilize in vitro gene array studies to display significant stimulation or inhibition of various human skin biomarkers to validate in vivo actions that are reported to enhance dermal health. This follows the central dogma of DNA-to-RNA results in protein expression; however, gene and protein expressions do not usually correlate. Unless both gene and protein expressions are quantified which require further investigational time and investment. Where data are available, this short commentary displays the in vitro comparison of four human skin biomarkers for the gene and protein expressions of the stimulation of collagen type I and elastin and the inhibition of matrix metalloproteinases 1 and 3, when equol was tested...
May 25, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28512843/assessment-of-the-efficacy-and-safety-of-a-new-complex-skin-cream-in-asian-women-a-controlled-clinical-trial
#13
Yu Seok Jung, Ji Hae Lee, Jung Min Bae, Dong Won Lee, Gyong Moon Kim
BACKGROUND: Medical products such as hydroquinone and tretinoin have been widely used to treat various types of skin hyperpigmentation. However, these products are limited in daily use given their adverse effects. Other alternative agents with fewer adverse side effects have been developed. However, single agents often do not produce satisfactory results. AIMS: To evaluate the efficacy and safety of a new brightening complex cream containing niacinamide, tranexamic acid, oxyresveratrol, glutathione disulfide, and linoleic acid...
May 16, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28509378/evaluation-of-the-skin-phototoxicity-and-photosensitivity-of-honeybee-venom
#14
Sang Mi Han, In Phyo Hong, Soon Ok Woo, Se Gun Kim, He Rye Jang, Kwan Kyu Park
OBJECTIVE: Bee (Apis mellifera L.) venom (BV) has been used as a cosmetic ingredient owing to its anti-aging, anti-inflammatory, and antibacterial effects. The aim of this study was to assess the skin safety of BV. METHODS: For this purpose, skin phototoxicity and sensitization tests were conducted in healthy male Hartley guinea pigs. The animals were divided into three groups (n=5) for the phototoxicity test: G1 (negative control), G2 (BV gel treatment), and G3 (positive control)...
May 16, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28504480/therapeutic-effect-of-microneedling-and-autologous-platelet-rich-plasma-in-the-treatment-of-atrophic-scars-a-randomized-study
#15
Zeinab A Ibrahim, Amal A El-Ashmawy, Ola A Shora
BACKGROUND: New treatments and techniques were being added over the last few years to treat atrophic scars with variable results and adverse effects. AIM OF THE WORK: The aim of this study was to evaluate and compare the therapeutic efficacy and safety of microneedling, autologous platelet-rich plasma, and combination of both procedures in the treatment of atrophic scars. PATIENTS AND METHODS: This study included 90 patients with atrophic scars and were classified randomly into three groups: I: 28 patients treated with microneedling, one session every 4 weeks; II: 34 patients treated with intradermal injection of platelet-rich plasma, one session every 2 weeks; and III: 28 patients treated with alternative sessions of each microneedling and platelet-rich plasma, 2 weeks between each session, for a maximum of six sessions...
May 14, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28504468/incubatory-environment-of-the-scalp-impacts-pre-emergent-hair-to-affect-post-emergent-hair-cuticle-integrity
#16
James R Schwartz, James P Henry, Kathy M Kerr, Michael J Flagler, Steve H Page, Nancy Redman-Furey
OBJECTIVES: To determine whether the oxidative stress transmitted to newly grown hair from an unhealthy scalp has physical consequences to the cuticular condition and function. METHODS: A uniquely designed 24-week clinical study included 8 weeks of pretreatment with a cosmetic shampoo and 16 weeks of treatment with either a potentiated zinc pyrithione (ZPT) antidandruff shampoo or a placebo cosmetic shampoo. This clinical design allowed the growth and acquisition of hair samples under conditions of varying but known scalp health as a result of treating a dandruff/seborrheic dermatitis (D/SD) population...
May 14, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28503741/the-effect-of-autologous-activated-platelet-rich-plasma-injection-on-female-pattern-hair-loss-a-randomized-placebo-controlled-study
#17
Abeer Attia Tawfik, Mai Abdel Raouf Osman
BACKGROUND: Hair is an essential part of a woman's appearance and attractiveness. This is reflected in the predominantly psychological morbidity that can be associated with female pattern hair loss. Platelet-rich plasma(PRP) has been used in numerous fields of medicine. Recently, PRP has received growing attention as a potential therapeutic tool for hair loss. OBJECTIVE: To evaluate the efficacy and safety of autologous platelet-rich plasma in the treatment of female pattern hair loss...
May 14, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28488347/the-efficacy-of-a-lip-balm-containing-pseudo-ceramide-on-the-dry-lips-of-sensitive-skin-conscious-subjects
#18
Keiichi Isoda, Tadashi Nakamura, Kensuke Yoshida, Eiko Tamura, Nami Atsuta, Koichi Ishida, Yutaka Takagi, Hitoshi Mizutani
BACKGROUND: Many people use lip care products daily to prevent dry lips. However, some people, especially those with sensitive skin-consciousness, complain of various skin problems on their lips including contact dermatitis caused by lip care products. Dry lips have decreased water holding capacity and cutaneous barrier function as well as reduced stratum corneum ceramide levels. In this study, we investigated the usefulness of a newly formulated lip balm containing pseudo-ceramide for the dry lips of subjects with sensitive skin...
May 9, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28447433/serum-vitamin-d-level-is-related-to-disease-severity-in-pediatric-alopecia-areata
#19
Mehmet Unal, Gulsum Gonulalan
BACKGROUND: Alopecia areata (AA) is the most common cause of inflammatory hair loss. AA is considered an autoimmune disease and occurs with various autoimmune disorders. Recent studies have revealed connection between autoimmune diseases and vitamin D deficiency. OBJECTIVES: In this study, we investigated vitamin D status in AA and its relationship with disease severity, number of patches, and disease duration. METHODS: This study included 20 pediatric patients with AA and 34 pediatric healthy controls...
April 26, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28432727/efficacy-of-fractionated-microneedle-radiofrequency-with-and-without-adding-subcision-for-the-treatment-of-atrophic-facial-acne-scars-a-randomized-split-face-clinical-study
#20
Gita Faghihi, Nazila Poostiyan, Ali Asilian, Bahareh Abtahi-Naeini, Masoom Shahbazi, Fariba Iraji, Farahnaz Fatemi Naeini, Mohammad Ali Nilforoushzadeh
BACKGROUND: There is no gold standard treatment for facial acne scars, and overall, little literature exists about the combination therapy for treatment of acne scar. AIMS: The aim of this study was to evaluate the efficacy of fractionated microneedle radiofrequency (FMR) vs FMR combined with subcision for the treatment of atrophic acne scars. PATIENTS/METHODS: This was a randomized, split-face clinical study of 25 patients with II-IV Fitzpatrick skin types with moderate to severe facial atrophic acne scars...
April 22, 2017: Journal of Cosmetic Dermatology
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