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Journal of Cosmetic Dermatology

Napatthaorn Pongsrihadulchai, Thep Chalermchai, Suwirakorn Ophaswongse, Suriya Pongsawat, Montree Udompataikul
BACKGROUND: Striae distensae (SD) is a form of dermal scar. A number of treatments have been proposed, but they usually have unsatisfactory result especially in striae alba. Recently, nanofractional RF has been developed. Its mechanism of action is to stimulate dermal remodeling and epidermal re-epithelization. AIM: To evaluate the efficacy and safety of nanofractional RF in the treatment of striae alba. PATIENTS/METHODS: This is an experimental, assessor-blinded, before-after study...
October 21, 2016: Journal of Cosmetic Dermatology
Vahideh Lajevardi, Afsaneh Ghayoumi, Robabeh Abedini, Hamed Hosseini, Azadeh Goodarzi, Zahra Akbari, Kosar Hedayat
BACKGROUND: Melasma's high prevalence and profound psychological impact on patients necessitate efficacious, economical, and safe therapeutic interventions. Adjunctive therapies such as tranexamic acid (TA) can enhance the therapeutic effect of standard treatments like hydroquinone 4% cream (HQ). OBJECTIVE: To conduct an assessor- and analyst-blinded, parallel, superiority, randomized controlled trial to compare the clinical efficacy and safety of oral TA plus HQ vs...
October 20, 2016: Journal of Cosmetic Dermatology
Jin Ok Baek, Hoon Hur, Ha Ryeong Ryu, Jeong Soo Kim, Kyung Real Lee, Yu Ri Kim, Kwang Ho Choi
Various lasers have been used for the treatment of erythematotelangiectatic rosacea (ETR) that does not respond to systemic or topical therapy. The pulsed dye lasers (PDLs) are an effective option for ETR, and the purpuragenic fluence proved to be superior until now. Given that purpura and subsequent possible postinflammatory hyperpigmentation (PIH) are occasionally unbearable in some patients, and several studies using the low nonpurpuragenic fluence were reported. To deliver the sufficient high fluence of a PDL without generating purpura, we designed the fractionation of high fluence using five passes and longer pulse duration (6 milliseconds) of a PDL in succession...
October 20, 2016: Journal of Cosmetic Dermatology
Nan Chen, Jingying Sun, Yali Song, Xinjing Wei, Yan Shi, Li Zhang
BACKGROUND: Mutations of keratin 9 (KRT9) gene is a hot research area of epidermolytic palmoplantar keratoderma (EPPK). AIMS: To identify the genes caused the EPPK of a Chinese family. PATIENTS/METHODS: Three cases of lesions were collected for pathological examination. Genomic DNA was extracted from peripheral blood samples of six patients and five healthy individuals and 100 unrelated individuals. Polymerase chain reaction (PCR) was used to amplify exons 1 of KRT9 gene...
October 10, 2016: Journal of Cosmetic Dermatology
Alisa A Sharova
The most international dosing guidelines on the use of botulinum toxin type A (BTXA) drugs support a 1:1 dose relationship between OnaBTXA and IncoBTXA and 1:2.5 between OnaBTXA and AboBTXA. However, different facial zones demonstrate different doses conversion ratios. The comparative analysis of nine consensuses on the use of Abo-, Ona-, and IncoBTXA in the United States, Russia, and Europe has been performed. We conducted a review of publications adopting the key words "botulinum toxin consensus," "botulinum toxin guideline...
October 3, 2016: Journal of Cosmetic Dermatology
Erling Thom
Postpartum effluvium is a well-known clinical fact. However, following some minor research activities in the 1960s, very little has happened on the research front of the subject. It was hypothesized that postpartum hair loss might be a manifestation of a change in the hair growth cycle occurring normally during pregnancy. Recently, new research has been published trying to explain the mechanism of action behind this frequently occurring hair growth disruption, and to develop a functional treatment schedule and regime...
September 23, 2016: Journal of Cosmetic Dermatology
Rungsima Wanitphakdeedecha, Chanida Ungaksornpairote, Arisa Kaewkes, Viboon Rojanavanich, Weeranut Phothong, Woraphong Manuskiatti
BACKGROUND: Botulinum toxin type A (BTA) has been approved for the treatment of strabismus, blepharospasm, muscle spasm, cervical dystonia, pain syndrome, glabella wrinkles, and severe primary axillary hyperhidrosis. Intradermal injection of BTA has been used off-label by many clinicians for the purpose of face-lifting effect. Few studies on onabotulinumtoxinA (ONA) demonstrated no clinical efficacy on face-lifting effect when comparing to normal saline solution (NSS). So far, there is no split-face comparison study on face-lifting effect of abobotulinumtoxinA (ABO)...
September 19, 2016: Journal of Cosmetic Dermatology
Weeranut Phothong, Rungsima Wanitphakdeedecha, Phawin Keskool, Woraphong Manuskiatti
Botulinum toxin type A (BTX-A) is now extensively employed for cosmetic concerns. Upper face rejuvenation, including glabella frown lines and crow's feet lines, received FDA approval for cosmetic uses. However, other off-label uses for lower face conditions have been employed for texture and contouring purposes, including masseter hypertrophy and vertical banding of the neck. BTX-A for rejuvenation of the aging neck is an effective and popular treatment with high patient satisfaction rates. Alleviating the aging appearance of the neck by BTX-A is the result of denervation of hyperkinetic platysma...
September 16, 2016: Journal of Cosmetic Dermatology
Sungsik Shin, Jung U Shin, Youngin Lee, Tae Gwang Kwon, Ju Hee Lee
BACKGROUND: Patients who receive laser treatments may experience transient erythema, edema, and crusts for several days. Although a variety of growth factor-containing creams for promoting recovery after laser treatment are available, evidence for their efficacy remains insufficient. AIMS: We performed a randomized controlled split-face study to assess the effects of a multigrowth factor (MGF)-containing cream on patients recovering from laser treatment. MATERIALS AND METHODS: Twenty patients underwent treatment using an ablative fractional laser and were randomized with respect to the side of the face treated with an MGF-containing cream or control cream...
September 16, 2016: Journal of Cosmetic Dermatology
Robabeh Alijanpour, Fatemeh Aliakbarpour
BACKGROUND AND OBJECTIVES: Hirsutism or excess hair growth is a common dermatological problem in females, affecting up to 10% of females worldwide. We aimed this study to compare the two hair-shortening methods shaving vs. snipping among hirsute women regarding the outcome of the therapy and also the paradoxical hypertrichosis phenomenon (terminal hair regrowth) 6 months after the final therapy session. MATERIALS AND METHODS: In this study, 129 premenopausal women affected by hirsutism were randomly divided into two study groups according to hair-shortening method: shaving as group A (66 patients) and hair shortening by scissor as group B (63 patients)...
September 11, 2016: Journal of Cosmetic Dermatology
Myeongryeol Lee, Yuchul Jung, Eunjoo Kim, Hae Kwang Lee
BACKGROUND: Skin properties vary depending on exogenous factors. Various studies have been used for comparing skin properties between cities for studying environment influence on skin properties. However, for comparison of skin properties between cities, various environmental factors have to be considered. OBJECTIVES: The purpose of this study therefore was to compare skin properties in individuals of the same ethnicity and sex (Indonesian women) between different altitudes and to interpret the environmental effect on skin...
September 11, 2016: Journal of Cosmetic Dermatology
Perihan Ozturk, Hakan Kıran, Ergul Belge Kurutas, Kamil Mulayim, Fazıl Avcı
OBJECTIVE: Striae gravidarum is a form of scarring on the skin observed during pregnancy and can cause serious cosmetic problems. Striae gravidarum may be influenced by hormonal changes, although the etiology is not clear. The aim of this study was to investigate whether body mass index (BMI) and serum collagenase-2 levels in pregnant women are related to the development of striae gravidarum. METHODS: Thirty pregnant women with striae, 30 pregnant women without striae, and 32 health controls were enrolled in the study...
September 7, 2016: Journal of Cosmetic Dermatology
Thomas A Swain, Albert Scott Tully, Travis Redford, Gerald McGwin
BACKGROUND: Hair removal practices have changed in frequency and location on the body. Previous research on hair removal injuries has focused on a specific body region, age, or gender. OBJECTIVE: This study sought to take a broader perspective of hair removal-associated injuries in the United States which sought treatment at emergency departments. METHODS: Data from the National Electronic Injury Surveillance System (NEISS) from 1991 to 2014 were used to identify hair removal-related injuries...
September 5, 2016: Journal of Cosmetic Dermatology
Karim N Jallad
Although the sun is very beneficial and essential for life, exposing ourselves too much to sunlight might lead to detrimental health effects such as skin cancer. Eight percent of the total different electromagnetic radiation that regularly irradiates the earth is classified as ultraviolet (UV) radiation. The ozone layer absorbs the most energetic UV rays; consequently, UV-A and UV-B reach the earth surface. UV-A rays heavily contribute to both premature skin aging and skin cancer, while UV-B rays cause sunburn...
September 5, 2016: Journal of Cosmetic Dermatology
Orsolya N Horváth, Valerie Letulé, Thomas Ruzicka, Thomas Herzinger, Ilana Goldscheider, Tanja von Braunmühl
A 32-year-old Caucasian woman was admitted to our outpatient department with periocular discoloration. She applied a serum with the active ingredient isopropyl cloprostenate for enhancing the growth of the eyelashes. The discoloration appeared for the first time when the patient had used the serum and gradually remitted after the discontinuation of use. Confocal laser scanning microscopy revealed small white spots in the perifollicular dermis and in the surrounding dilated vessels, which was reported earlier as a side effect of prostaglandin analogs...
September 5, 2016: Journal of Cosmetic Dermatology
Betul Gozel Ulusal
BACKGROUND: Cosmetic applications of platelet-rich plasma (PRP) are new, and reports are scarce and dispersed in the literature. There are a variety of commercially available kits and injection techniques, and the number and intervals of injections vary. New investigations should focus on developing a standardized procedure for PRP preparation and application methods to augment its efficacy and potency. OBJECTIVES: In this report, we aim to provide data and commentary to assist and add to current guidelines...
September 5, 2016: Journal of Cosmetic Dermatology
Surabhi Dayal, Ashish Amrani, Priyadarshini Sahu, Vijay Kumar Jain
INTRODUCTION: Chemical peeling is a well-identified therapeutic modality for acne vulgaris (AV). Jessner's solution (JS) is a known peeling agent for acne since more than 100 years. Salicylic acid (SA) peel is a well-established peeling agent for acne. There is paucity of literature comparing the current peeling agents of choice, that is, SA with the older peeling agents, that is, JS for acne. OBJECTIVE: To compare the efficacy and safety of 30% SA vs. JS peels in treatment of mild-to-moderate facial acne in Indian patients...
August 25, 2016: Journal of Cosmetic Dermatology
Georgios Zontos, Ken L Williams, George Nikiforidis
BACKGROUND: Follicular Unit Extraction (FUE) is considered to be a minimally invasive procedure, and the injury to the donor area caused by a sharp punch may result in dermal fibrosis and clinically observed hypopigmentation. OBJECTIVE: To evaluate with advanced image processing the efficacy of using 0.9% normal saline in minimizing the injury to the donor area in FUE donor harvesting. PATIENTS AND METHODS: The term acute extraction (AE) is used to describe the donor harvesting technique, whereby a follicular unit (FU) is removed with a punch that is aligned parallel with the exit angle of the hair follicle...
August 24, 2016: Journal of Cosmetic Dermatology
Felix Boon-Bin Yap
INTRODUCTION: Low-dose isotretinoin is used to reduce side effects albeit higher relapse. This study aimed to determine the efficacy and safety of fixed-dose 10 mg daily isotretinoin for the treatment of acne. METHODS: This prospective study was performed between 2011 and 2015. All 150 patients were given 10 mg daily isotretinoin until a cumulative dose of 90-110 mg/kg. RESULTS: The mean age was 26.6 years with 64.7% moderate acne, 29...
August 18, 2016: Journal of Cosmetic Dermatology
Nam Young Kim, Hee Souk Kwon, Hyeon Yong Lee
BACKGROUND: This work presents the first report that A. rugosa could have tyrosinase and melanogenesis inhibition and that its activities also be improved by fermentation with Lactobacillus rhamnosus and Lactobacillus paracasei. It was found that the tyrosinase and melanogenesis inhibition was correlated with antioxidant activity of acacetin, the major biologically active substances in A. rugosa. AIMS: we pursued an improvement in tyrosinase and melanogenesis inhibition of A...
August 16, 2016: Journal of Cosmetic Dermatology
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