Antibiotic resistance of enterobacterial pathogens isolated on the territory of the Northern Kazakhstan.

The purpose of this study was to isolate and identify strains of infectious disease pathogens and to determine their antibacterial drug resistance. From 2018-2020, 5322 samples of biological material from animals and birds, products of animal origin were taken at retail outlets, livestock enterprises in Kostanay and North Kazakhstan regions. In the study territories of 20 districts and 4 cities were covered. Phenotypic resistance analysis of the recovered isolates of Salmonella spp. showed a high level of resistance to antibiotics of the tetracyclines (82/137) and nitrofurans (81/137) groups. S. aureus isolates had increased resistance to the β-lactams (124/131) and macrolides (96/131) groups. As a result, the largest number of genes encoding resistance was found to the β-lactams, aminoglycosides, tetracyclines and macrolides groups. The study was carried out within the framework of the project AR05131447 "Monitoring of antibiotic resistance of pathogens of enteropathogenic zooanthroponosis diseases in the Northern Kazakhstan".