We have located links that may give you full text access.
Case Reports
Journal Article
Unusual Case of Nail Unit Melanoma.
American Journal of Dermatopathology 2020 April
We present a case of a nail unit melanoma with chondroid differentiation that was initially misdiagnosed as a benign chondroid neoplasm. A 67-year-old Caucasian woman presented to an outside dermatologist with a tender subungual nodule on the right index finger with overlying nail plate changes that had been present and enlarging for 1 year. Initial histopathological evaluation rendered a diagnosis of benign chondroid neoplasm. On arrival to our institution, magnetic resonance imaging was performed, and the lesion appeared consistent with a glomus tumor. Plastic surgery performed a surgical resection with intraoperative frozen sections revealing a hypocellular cartilaginous mass, but pathology was unable to comment on the presence of malignant cells. On permanent sectioning of the excised lesion, a lentiginous proliferation of melanocytes overlying a dermal aggregate of atypical cells with conspicuous mitoses embedded in a chondroid matrix was seen. A panel of immunohistochemical stains was performed, including SOX-10, HMB-45, S-100, MITF and MART1 was performed with SOX-10, HMB-45, and S-100 staining the junctional melanocytes and dermal cells, rendering a diagnosis of primary chondroid melanoma.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app