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American Journal of Dermatopathology

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https://www.readbyqxmd.com/read/28323762/utility-of-examining-deeper-levels-and-or-special-stains
#1
Henry R Jakubovic
No abstract text is available yet for this article.
March 17, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28296664/histomorphology-and-immunophenotype-of-eczematous-skin-lesions-revisited-skin-biopsies-are-not-reliable-in-differentiating-allergic-contact-dermatitis-irritant-contact-dermatitis-and-atopic-dermatitis
#2
Verena G Frings, Almut Böer-Auer, Kristine Breuer
Lesions of allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), and atopic dermatitis (AD) share similar clinical features and thus, their diagnosis can be challenging. The aim of this study was to reassess histopathology and immunophenotyping properties to distinguish between ACD, ICD, and AD. Charts of patients with eczema, who had undergone complete routine diagnostic workup (skin biopsies, patch tests, skin prick tests, and respectively or serum IgE levels), were reviewed. Thirty-five skin biopsy specimens of 28 patients (mean age 64 ± 15 years; ♀ = 13 ♂ = 15) with clear diagnosis of ACD (n = 15), ICD (n = 6), or AD (n = 14) were analyzed...
March 10, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291132/subcutaneous-histiocytoid-sweet-syndrome-in-a-patient-with-relapsed-acute-myeloblastic-leukemia
#3
Jennifer Lee, Kristine M Cornejo, Jillian Rork, Karen Rothman, April Deng
No abstract text is available yet for this article.
March 9, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291131/study-of-selected-brca1-brca2-and-pik3ca-mutations-in-benign-and-malignant-lesions-of-anogenital-mammary-like-glands
#4
Anastasia M Konstantinova, Ksenya V Shelekhova, Evgeny N Imyanitov, Aglaya Iyevleva, Denisa Kacerovska, Michal Michal, Dmitry V Kazakov
Anogenital mammary-like glands (AGMLGs) are nowadays considered a normal component of the anogenital area. Lesions involving AGMLGs are histopathologically very similar to their mammary counterparts, but the information on molecular biological mechanisms in these vulvar/perianal tumors is scarce. Mutations in the PI3K-AKT cascade have been found in hidradenoma papilliferum. The authors studied selected BRCA1, BRCA2, and PIK3CA mutations in series of benign and malignant neoplasms thought to be associated with AGMLGs, including 9 cases of primary extramammary Paget disease, 3 different cases of mammary-type carcinoma (adenoid cystic like, tubulolobular, and invasive ductal like), and 5 cases of hidradenoma papilliferum...
March 9, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291140/melanoma-manifesting-as-tumoral-melanosis-now-you-see-it-now-you-don-t
#5
Robert L Grohs, Nima Mesbah Ardakani
No abstract text is available yet for this article.
February 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291139/nonhealing-ulcerations-of-the-breast-challenge
#6
Carlos J Sarriera-Lázaro, Jorge L Sánchez-Colón, Aileen E Santos-Arroyo
No abstract text is available yet for this article.
February 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291138/nonhealing-ulcerations-of-the-breast
#7
Carlos J Sarriera-Lázaro, Jorge L Sánchez-Colón, Aileen E Santos-Arroyo
No abstract text is available yet for this article.
February 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291137/on-allusive-names-for-the-syphilitic-patient-from-the-16th-to-the-19th-century-the-role-of-dermatopathology
#8
Anna Piro, Antonio Tagarelli
No abstract text is available yet for this article.
February 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291136/bilateral-and-symmetrical-linear-plaques-on-the-hands
#9
Zhouwei Wu, Mingyuan Xu, Zhuo Chen, Weimin Shi, Yeqiang Liu
No abstract text is available yet for this article.
February 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291135/depletion-of-epidermal-langerhans-cells-in-the-skin-lesions-of-pellagra-patients
#10
Sayaka Yamaguchi, Takuya Miyagi, Yoko Sogabe, Masahito Yasuda, Nobuo Kanazawa, Atsushi Utani, Seiichi Izaki, Hiroshi Uezato, Kenzo Takahashi
Pellagra is a nutrient deficiency disease caused by insufficient niacin levels. Recent studies have shown that numbers of epidermal Langerhans cells decreased in other diseases caused by nutritional deficiencies, including necrolytic migratory erythema and acrodermatitis enteropathica. Epidermal Langerhans cells are capable of modulating or even halting the inflammatory reaction. The aim of this study was to examine changes in the number of Langerhans cells and other dendritic cells, and maturation of epidermal Langerhans cells in the lesional and adjacent non-lesional skin in pellagra patients...
February 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291134/a-rapidly-growing-facial-mass-challenge
#11
Anna K Dewan, Deanna Dickerman, Eric Tkaczyk, Jeffrey P Zwerner, Alan Boyd, Jami L Miller
No abstract text is available yet for this article.
February 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28291133/a-rapidly-growing-facial-mass-answer
#12
Anna K Dewan, Deanna Dickerman, Eric Tkaczyk, Jeffrey P Zwerner, Alan Boyd, Jami L Miller
No abstract text is available yet for this article.
February 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28266938/follicular-porokeratosis-a-porokeratosis-variant
#13
Ben Tallon, Patrick Emanuel
Porokeratosis derives from a process of abnormal keratinization, resulting in clinical and histologic variants. Follicular involvement is infrequently described, with previous suggestions that it may represent a distinct condition. We describe a case of typical disseminated superficial actinic porokeratosis with additional clinically prominent folliculocentric keratosis. Histologically, this represented follicular cornoid lamellae. These findings support follicular porokeratosis as an anatomic site variant of porokeratosis, as opposed to a distinct condition...
February 27, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28248716/intraepithelial-melanoma-in-the-stomach-after-treatment-with-immune-checkpoint-blockade-therapy
#14
Elina Shustef, Carlos A Torres-Cabala, Jonathan L Curry, Michael T Tetzlaff, Priyadharsini Nagarajan, Doina Ivan, Victor G Prieto, Phyu P Aung
Melanoma is the most common tumor to metastasize to the gastrointestinal tract, commonly affecting the small intestine, colon, and anorectum. Primary mucosal melanoma can arise in any gastrointestinal site, most frequently affecting anorectal mucosa. Melanoma involving the gastric mucosa, specifically, is exceedingly rare and carries a poor prognosis with a median survival of 5 months. The presence of atypical melanocytes exclusively within gastric epithelium has not been previously described. We report a case of a 52-year-old man with widespread BRAFV600E mutant metastatic melanoma who was referred to our institution for immune checkpoint antibody-blockade therapy...
February 23, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28248717/mass-spectrometry-imaging-can-distinguish-on-a-proteomic-level-between-proliferative-nodules-within-a-benign-congenital-nevus-and-malignant-melanoma
#15
Rossitza Lazova, Zhe Yang, Constantin El Habr, Young Lim, Keith Adam Choate, Erin H Seeley, Richard M Caprioli, Li Yangqun
Histopathological interpretation of proliferative nodules occurring in association with congenital melanocytic nevi can be very challenging due to their similarities with congenital malignant melanoma and malignant melanoma arising in association with congenital nevi. We hereby report a diagnostically challenging case of congenital melanocytic nevus with proliferative nodules and ulcerations, which was originally misdiagnosed as congenital malignant melanoma. Subsequent histopathological examination in consultation by one of the authors (R...
February 20, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28248720/hydroa-vacciniforme-like-t-cell-lymphoma-a-further-brazilian-case
#16
Mario Fernando Ribeiro de Miranda, Josie Eiras Bisi Dos Santos, Silvia Ferreira Rodrigues Müller, Maraya de Jesus Semblano Bittencourt, Arival Cardoso de Brito, Jorge Nazareno da Silva Barros Junior, Ellen Maria Sampaio Xerfan
Hydroa vacciniforme (HV)-like lymphoma is a rare, usually fatal Epstein-Barr virus-driven lymphoproliferative disease affecting children from Asia, Mexico, and South America. Cutaneous manifestations imitate HV, a benign photodermatosis in which systemic symptoms are not observed, and spontaneous regression occurs later in adolescence or young adulthood. We report a case of HV-like lymphoma in a 12-year-old girl, descendent from an ancient Amazon indigenous tribe that, as far as we know, represents the second Brazilian case ever reported in the medical literature...
February 15, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28248719/nonhealing-ulcerated-nodules-in-a-sporotrichoid-pattern-following-recent-travel
#17
Alejandro Rabionet, Jennifer Divine, Nishit Patel
No abstract text is available yet for this article.
February 15, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28248718/nonhealing-ulcerated-nodules-in-a-sporotrichoid-pattern-after-recent-travel
#18
Alejandro Rabionet, Jennifer Divine, Nishit Patel
No abstract text is available yet for this article.
February 15, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28244939/benign-atrophic-papulosis-degos-disease-with-lymphocytic-vasculitis-and-lichen-sclerosus-like-features
#19
Esther Kim, Kiran Motaparthi
Degos disease manifests as 2 distinct clinical variants, malignant atrophic papulosis and benign atrophic papulosis, which are distinguished by the presence or absence of systemic disease. Both forms feature cutaneous involvement typified by erythematous papules with scar-like centers, and the classic histologic picture is described as wedge-shaped dermal necrosis overlying thrombotic vasculopathy. However, the histopathology of early lesions is distinct and more variable. A case of benign atrophic papulosis with lymphocytic vasculitis and lichen sclerosus-like features is described, and the spectrum of histologic findings in Degos disease is reviewed...
February 14, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28244938/actinic-granuloma-annulare-with-scarring-and-open-comedones
#20
Cfb Gavioli, Nys Valente, M Sangueza, M M Nico
Actinic granuloma and annular elastolytic giant cell granuloma are variants of granuloma annulare affecting, respectively, sun-exposed and sun-covered skin sites on where, besides classical findings, abundant elastophagocytosis is observed. Here, we report a case of exuberant actinic granuloma annulare that, in addition to extensive scarring, showed multiple overlying open comedones. Markedly dilated follicular infundibula filled with compact masses of laminated keratinous material were observed in proximity to dermal inflammation composed of many histiocytes and multinucleated giant cells in close association with degenerated elastic fibers and abundant elastophagocytosis...
February 14, 2017: American Journal of Dermatopathology
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