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American Journal of Dermatopathology

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https://www.readbyqxmd.com/read/28521332/tuberculosis-of-lip-an-unusual-presentation
#1
Abhimanyu Sharma, Vinod K Arora
No abstract text is available yet for this article.
May 9, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28509701/educational-gaps-in-molecular-diagnostics-genomics-and-personalized-medicine-in-dermatopathology-training-a-survey-of-us-dermatopathology-fellowship-program-directors
#2
Kristin Torre, Kristen Russomanno, Tammie Ferringer, Dirk Elston, Michael J Murphy
BACKGROUND: Molecular technologies offer clinicians the tools to provide high-quality, cost-effective patient care. We evaluated education focused on molecular diagnostics, genomics, and personalized medicine in dermatopathology fellowship. DESIGN: A 20-question online survey was emailed to all (n = 53) Accreditation Council for Graduate Medical Education (ACGME)-accredited dermatopathology training programs in the United States. RESULTS: Thirty-one of 53 program directors responded (response rate = 58%)...
May 2, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475520/mucocutaneous-hyperpigmentation-in-a-patient-with-a-history-of-both-minocycline-and-silver-ingestion
#3
Angel Fernandez-Flores, Thao Nguyen, David S Cassarino
Minocycline is a derivative of tetracycline. It has been widely used in dermatology for the treatment of acne and rosacea. One of its adverse effects is pigmentation of various body tissues. Clinically, 3 main distinct types of hyperpigmentation by minocycline have been distinguished: type I, with blue-gray to black pigment on the face in areas of scarring or inflammation; type II, with blue-gray pigment on normal skin of the legs, forearms and on the shins; and type III, with a diffuse muddy-brown discoloration in areas of sun exposure...
April 27, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475519/genomic-assessment-of-blitz-nevi-suggests-classification-as-a-subset-of-blue-nevus-rather-than-spitz-nevus-clinical-histopathologic-and-molecular-analysis-of-18-cases
#4
Maria C Isales, Alexandra M Haugh, Jeffrey Bubley, Anna E Verzì, Bin Zhang, Emily Kudalkar, Christina Y Lee, Pedram Yazdan, Joan Guitart, Pedram Gerami
Blitz nevi/tumors are a distinct subset of melanocytic neoplasia which show mixed morphologic features of Spitz and blue nevus. Genomically, most blue nevi have GNAQ or GNA11 mutations while most Spitzoid neoplasms have either an HRAS mutation or translocations involving MET, ROS, BRAF, ALK1, NTRK1, and RET. The criteria used for the assessment of malignancy in blue and Spitzoid lesions are different, and these lesions have different prognostic markers. In this study, we assess the clinical, morphological, and genomic changes in 18 cases of Blitz nevi/tumors to better characterize this subset of neoplasms and determine their optimal genomic classification...
April 27, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475518/palisaded-neutrophilic-and-granulomatous-dermatitis-interstitial-granulomatous-dermatitis-overlap-a-striking-clinical-and-histologic-presentation-with-burning-rope-sign-and-subsequent-mirror-image-contralateral-recurrence
#5
Malan Kern, Mallory B Shiver, Kristen M Addis, Jerad M Gardner
Palisaded neutrophilic and granulomatous dermatitis and interstitial granulomatous dermatitis are uncommon granulomatous dermatoses that often arise in association with rheumatoid arthritis. These 2 entities have overlapping features and may exist on a spectrum. We report an intriguing case of a 53-year-old man with advanced rheumatoid arthritis who presented with a large indurated painful truncal plaque with a palpable cord in addition to a papulonodular eruption on his dorsal hands. Furthermore, our patient had a recurrence in a near-identical mirror-image pattern on the contralateral trunk...
April 27, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475517/hailey-hailey-disease-with-coexistent-herpes-virus-infection-insights-into-the-diagnostic-conundrum-of-herpetic-pseudoherpetic-features-in-cutaneous-acantholytic-disorders
#6
Claire S Leitch, Anusha P Panthagani, Michael J Tidman, Asok Biswas
The specific histopathologic diagnosis of a primary acantholytic disorder takes into account the distribution and extent of acantholysis, presence or absence of dyskeratosis, nature of the dermal inflammatory cell infiltrate, and immunofluorescence findings. Herpes virus infection is a common cause of secondary acantholysis where distinctive viral cytopathic changes aid in making it a clear-cut diagnosis in majority of cases. We present a case of coexistence of Hailey-Hailey disease and herpes simplex virus infection to compare and contrast their histopathologic features...
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475516/unusual-case-of-dactylitis-with-nail-unit-involvement
#7
Isabelle Moulonguet, Philippe Abimelec
No abstract text is available yet for this article.
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475515/annular-lichenoid-dermatitis-of-youth-report-of-a-case-with-lichen-planus-like-features
#8
Anna M Cesinaro
Annular lichenoid dermatitis of youth (ALDY), a dermatosis with peculiar clinical and pathological features, represents still a debated entity, given its similarity, among others, with mycosis fungoides. A case of ALDY in a 50-year-old male patient is reported. Clinically, the patient presented an oval scleroderma-like plaque on the right flank. Histology and immunohistochemistry showed the classic appearance described in ALDY. T-cell receptor rearrangement was absent. Interestingly, a focus consistent with lichen planus was observed...
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475514/recurrent-cutaneous-angiosarcoma-of-the-scalp-with-aberrant-expression-of-s100-a-case-report
#9
Laura Macías-García, Concepción Lara-Bohorquez, Enrique Jorquera-Barquero, Juan J Ríos-Martín
Angiosarcoma (AS) is a malignant mesenchymal neoplasm of endothelial origin with a predominantly lymphatic immunophenotype, which accounts for less than 1% of all sarcomas. Cutaneous AS of the scalp is associated with high rates of local recurrence and a poor prognosis. Histologically, poorly differentiated AS often comprises solid epithelioid cells, although rare variants involving spindle cells have been reported; diagnosis requires immunohistochemical analysis using vascular cell markers. We report on a cutaneous spindle-cell AS of the scalp in a female patient; key features included spontaneous regression after biopsy, local recurrence 2 years later, and aberrant nuclear staining for S100 protein in an area of the tumor not expressing CD34 or D2-40...
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475513/nodular-sclerodermatous-chronic-cutaneous-graft-versus-host-disease-gvhd-a-new-clinicopathological-variant-of-cutaneous-sclerodermatous-gvhd-resembling-nodular-keloidal-scleroderma
#10
Lucía Prieto-Torres, Francesca Boggio, Alexandra Gruber-Wackernagel, Lorenzo Cerroni
Cutaneous chronic graft-versus-host disease (GvHD) has a broad spectrum of clinicopathological presentations, the most common ones being poikiloderma, lichen planus-like eruptions, lichen sclerosus-like lesions, morphea-like plaques, and deep sclerosis. New forms of chronic cutaneous GvHD with different clinicopathological characteristics have been described, most of them mimicking cutaneous manifestations of autoimmune diseases. We report the case of a 35-year-old man who underwent allogenic stem cell transplantation for a therapy-associated acute myeloid leukemia and developed an acute GvHD with involvement of skin and gastrointestinal tract...
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475512/a-new-firm-solitary-nodule-in-a-patient-with-hiv-aids-question
#11
Andrew S Fischer, Neda Black, Brandon McNally, Joshua Wisell
No abstract text is available yet for this article.
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475511/cutaneous-plasmacytosis-a-clinicopathologic-study-of-a-series-of-cases-and-their-treatment-outcomes
#12
Xiuhui Debra Han, Siong See Joyce Lee, Suat Hoon Tan, Wei-Sheng Chong, See Ket Ng, Melissa Gaik Ming Ooi, Chee Leok Goh
INTRODUCTION: Cutaneous plasmacytosis (CP) is a rare skin disorder characterized by multiple reddish brown nodules with polyclonal plasma cell proliferation. It has most often been reported to affect the trunk but is also known to affect the face and extremities in adults and is predominantly seen in Asians. The etiology is poorly understood, and there is no consensus on treatment methods. METHODS: Five cases diagnosed to have CP were collated from our institution...
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475510/generalized-dyschromia-and-erythematous-papules-in-a-66-year-old-man
#13
Ali G Al-Haseni, Jonathan D Ho, Mayra B Maymone, Jag Bhawan, Neelam A Vashi
No abstract text is available yet for this article.
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475509/psoriasiform-hyperpigmented-plaques-of-the-palms-and-soles
#14
Tien Anh N Tran, Hughey C Carter, Joseph Conte, John A Carlson
No abstract text is available yet for this article.
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475508/primary-cutaneous-leiomyosarcoma-arising-in-a-patient-with-li-fraumeni-syndrome-a-neoplasm-with-unusual-histopathologic-features-and-loss-of-heterozygosity-at-tp53-gene
#15
Vicente Sabater-Marco, Francisco Ferrando-Roca, Arturo Morera-Faet, José Angel García-García, Sandra B Bosch, José A López-Guerrero
No abstract text is available yet for this article.
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28475507/a-not-so-benign-papular-eruption
#16
Basia Michalski, Donald A Hackbarth, Barbara D Wilson, Olayemi Sokumbi, JiaDe Yu
No abstract text is available yet for this article.
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28452793/painful-pustules-on-hands-and-feet-with-acute-hepatitis
#17
Ana Ortins-Pina, Isabel Viana, Paulo Filipe, Luís Soares-de-Almeida
No abstract text is available yet for this article.
April 14, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28410246/multiple-tumors-on-the-extremities
#18
Uzoamaka T Ukoha, Travis Vandergriff, Jonathan Cheng, Donald A Glass
No abstract text is available yet for this article.
April 14, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28452792/epidermolysis-bullosa-acquisita-brunsting-perry-pemphigoid-variant-localized-to-the-face-and-diagnosed-with-antigen-identification-using-skin-deficient-in-type-vii-collagen
#19
Leila Asfour, Heung Chong, John Mee, Richard Groves, Manuraj Singh
Brunsting-Perry pemphigoid is defined as an autoimmune vesiculobullous eruption typically localized on the head and neck region with minimal or no mucosal involvement. The disease tends to run a chronic and recurrent course with residual scarring. Histological features are characterized by subepidermal bullae and linear IgG deposits at the dermo-epidermal junction. We report a case of a 46-year-old lady who presented with typical features of Brunsting-Perry pemphigoid. Autoantibodies to type VII collagen were identified by using recessive dystrophic epidermolysis bullosa skin which lacks type VII collagen in an indirect immunofluorescence assay...
April 12, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28452794/cutaneous-presentation-of-a-testicular-germ-cell-tumor-with-seminomatous-differentiation
#20
Andrew S Fischer, Courtney Aldridge, Whitney A High
No abstract text is available yet for this article.
April 11, 2017: American Journal of Dermatopathology
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