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American Journal of Dermatopathology

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https://www.readbyqxmd.com/read/30398988/cytoimmunofluorescence-diagnosis-in-surgically-induced-pemphigus-foliaceus
#1
Jorge Magdaleno-Tapial, Cristian Valenzuela-Oñate, Macarena Giacaman-von der Weth, Marta García-Legaz Martínez, Pablo Hernández-Bel, Alexo Carballeira-Braña, José Luis Sánchez-Carazo, Víctor Alegre-de Miquel
Pemphigus foliaceus is an autoimmune bullous disease with autoantibodies against desmoglein 1. Case reports of pemphigus after surgery have also been described, which may simulate an infection of the surgical wound, a contact dermatitis, or even a tumor recurrence. Cytoimmunofluorescence can help to establish a rapid diagnosis.
November 1, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30398987/neutropenic-fever-and-a-diffuse-hyperpigmented-papular-rash-challenge
#2
Suchismita Paul, Preetha Kamath, George Elgart
No abstract text is available yet for this article.
October 31, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30398986/examination-of-tar-induced-verrucous-growths-reveals-absence-of-human-papillomavirus
#3
Kourosh Beroukhim, Jenny Z Wang, Joshua M Schulman, Ethan Levin, Wilson Liao, Melissa J Danesh
No abstract text is available yet for this article.
October 30, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30398985/syringocystadenoma-papilliferum-of-the-anogenital-area-and-buttocks-a-report-of-16-cases-including-human-papillomavirus-analysis-and-hras-and-braf-v600-mutation-studies
#4
Anastasia M Konstantinova, Liubov Kyrpychova, Jana Nemcova, Monica Sedivcova, Michele Bisceglia, Heinz Kutzner, Michal Zamecnik, Eva Sehnalkova, Michal Pavlovsky, Kamila Zateckova, Sergej Shvernik, Zuzana Spurkova, Michal Michal, Katrin Kerl, Dmitry V Kazakov
Syringocystadenoma papilliferum (SCAP) is a benign tumor most commonly located on the head and neck area often associated with nevus sebaceus. In its usual location, the human papillomavirus (HPV) DNA and mutations in the RAS/mitogen-activated protein kinase signaling pathway have been detected in SCAP. We studied 16 cases of SCAP in the anogenital areas and buttock where this neoplasm is rare and attempted to find out whether SCAP in these sites have different histopathological and molecular biological features...
October 29, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30398984/multiple-pilomatricomas-a-retrospective-study-and-literature-review
#5
Laura Mesa-Álvarez, Ana Batalla, Álvaro Iglesias-Puzas, Carlos Álvarez, Ángeles Flórez
Pilomatricoma is usually a single lesion. However, some patients present with more than one, a fact that has been reported in association with several systemic diseases. The aim of this analysis is to determine the prevalence of multiple pilomatricomas (MP) in our institution as well as to describe their clinical features and associated comorbidities. This is a retrospective analysis reviewing patients with a histological diagnosis of pilomatricoma registered in the database of the Pathology Department of our institution, from January 2005 to March 2017...
October 29, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30371514/syringotropic-lichen-planus-a-potential-histopathologic-mimicker-of-syringotropic-mycosis-fungoides
#6
Mauro Mazzeo, Andrea Saggini, Tea Rocco, Maria Concetta Fargnoli, Lorenzo Cerroni
Perieccrine inflammation may be observed in several different dermatoses, but true permeation of the secretory coil by lymphocytes (lymphocytic syringotropism) is a rather uncommon finding, usually observed in mycosis fungoides (MF-syringotropic MF). Rare cases of syringotropic lichen striatus and lymphocytic autoimmune hidradenitis showing a similar pattern have been described as well. We describe an exceptional case of lichen planus (LP) characterized by marked lymphocytic syringotropism with focal hyperplasia of the eccrine epithelium...
October 24, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30371513/a-granular-cell-tumor-appearing-at-a-vaccination-site-a-possible-reaction-to-trauma
#7
Orna Mirmovich Morvay, Ori S Duek, Reuven Bergman
No abstract text is available yet for this article.
October 24, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30371512/a-stab-in-the-back-an-unusual-case-of-cutaneous-neural-infiltration-as-a-manifestation-of-chronic-lymphoproliferative-disorder-of-natural-killer-cells
#8
Sarah Ní Mhaolcatha, Aoibheann Flynn, Brian Hayes, Derville OʼShea, Mary Bennett, James Fitzgibbon
Chronic lymphoproliferative disorder of natural killer cells (CLPDNK) is a rare heterogenous indolent disorder comprising a persistent peripheral blood cell count of more than ≥2 × 10/L natural killer cells for over 6 months. We report an unusual case of cutaneous neural infiltration as a manifestation of CLPDNK. A 52-year-old woman with a background of CLPDNK was referred to dermatology with a painful rash primarily affecting her back. Skin biopsies revealed a neurotropic atypical lymphoid infiltration...
October 24, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30371511/violaceous-plaques-and-nodules-challenge
#9
Maggie Chow, Sonia Kamath, David Choi, Gene Kim, Iris Ahronowitz
No abstract text is available yet for this article.
October 24, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30325752/tick-bite-associated-morphea-a-case-report
#10
Eva George, Colton B Nielson, Vladimir Vincek
Borrelia burgdorferi, the causative organism of Lyme disease, has been linked to the development of scleroatrophic skin conditions including morphea, although this association remains controversial. The possibility that tick bite with or without concurrent Borrelia infection instigates that morphea development is important to recognize because this could prompt further workup for Lyme disease, or other tick-borne illness, which, when untreated, can have devastating consequences. Here, we report a case of a woman with a history of previous tick bite in the location of morphea...
October 9, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30308545/primary-localized-cutaneous-amyloidosis-affecting-female-individuals-of-a-pakistani-pedigree
#11
Bevin Bhoyrul, Alicia Ng, Philip M Laws, Bipin Mathew, Sangeetha Shanmugam
Primary localized cutaneous amyloidosis is a group of rare conditions where amyloid deposition is limited to the skin without systemic manifestations. Most cases are sporadic; however, mutations in the oncostatin M receptor (OSMR) and interleukin-31 receptor A (IL31RA) genes can cause a familial form of the condition in up to 10% of cases. Here, we describe a family in which 8 female individuals are affected by either macular amyloidosis or amyloidosis cutis dyschromica. To the best of our knowledge, a sex-specific expression or the coexistence of 2 different phenotypes of primary localized cutaneous amyloidosis in 1 pedigree has not yet been reported...
October 9, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30308544/a-blue-gray-macule-on-the-back-challenge
#12
Oyinade Aderibigbe, Caroline Groft-MacFarlane, Emily Y Chu
No abstract text is available yet for this article.
October 9, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30308543/decreased-t-cell-programmed-death-receptor-1-expression-in-pregnancy-associated-melanoma
#13
Jennifer S Ko, Brian R Gastman, Ruzica Conic, Alejandra Tellez Diaz Trujillo, Claudia Marcela Diaz-Montero, Steven D Billings, Ahmad Tarhini, Pauline Funchain, Natasha Atanaskova Mesinkovska
INTRODUCTION: Pregnancy depends on tolerance of an immunologically foreign fetus through type 1 T-cell suppression. Worse melanoma outcomes have been described within 1 year of childbirth. We assessed immunopathologic factors that may account for the observed negative impact of pregnancy on outcome. MATERIALS AND METHODS: Women of child-bearing age with ≥24 months follow-up were identified from our Institutional Melanoma Registry. Women with available primary tumor blocks were compared [history of childbirth within 1 year of diagnosis (CB1Y) (n = 18) vs...
October 9, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30299274/in-response
#14
Elsa Bibiana Peña Zúñiga
No abstract text is available yet for this article.
October 5, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30289773/epithelioid-fibrous-histiocytoma-a-concise-review
#15
Cameron C Felty, Konstantinos Linos
Epithelioid fibrous histiocytoma (EFH) is a rare lesion believed to arise from dermal microvascular unit fibroblasts and dendritic histiocytes. EFH has long been considered a morphologic variant of benign fibrous histiocytoma (dermatofibroma), with prominent epithelioid cytomorphology that can mimic both vascular and melanocytic neoplasms. The molecular basis for the relationship between EFH and benign fibrous histiocytoma has remained largely unknown, with some authors suggesting that EFH represents an entity that is biologically distinct from benign fibrous histiocytoma...
October 4, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30289772/acquired-cutaneous-lymphangiectasia-secondary-to-cervical-cancer-treatment
#16
Ji Yeon Hong, Guk Jin Jung, Kapsok Li
No abstract text is available yet for this article.
October 4, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30260803/tender-nodules-and-swollen-red-legs-challenge
#17
Reginald M Ngwanya, Zandile Spengane, Michael Otto
No abstract text is available yet for this article.
September 26, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30252698/follicle-and-sebaceous-gland-multinucleated-cells-in-measles
#18
Jorge Magdaleno-Tapial, Cristian Valenzuela-Oñate, Macarena Giacaman-von der Weth, Blanca Ferrer-Guillén, Marta García-Legaz Martínez, Álvaro Martínez-Domenech, Pablo Hernández-Bel, Víctor Alegre-de Miquel
We report the case of a 32-year-old man with measles in which skin biopsy helped to establish a definitive diagnosis. Follicular involvement is a common histopathologic feature of measles. Multinucleated epidermal and follicular cells are distinctive findings.
September 24, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30252697/brooke-spiegler-syndrome-two-patients-from-a-turkish-family-with-multiple-familial-trichoepithelioma
#19
Gunes Cakmak Genc, Ahmet Dursun, Nikoletta Nagy, Ayca Celikmakas, Burcin Acuner
No abstract text is available yet for this article.
September 24, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/30252696/mucinous-metaplasia-of-the-vulva-in-zoon-vulvitis-and-lichen-sclerosus-et-atrophicus-description-of-3-additional-cases-of-a-rarely-reported-histopathologic-finding
#20
Carlos Santonja, José Manuel Suárez-Peñaranda, Loreto Carrasco, María Del Carmen Fariña, Luis Requena
Mucinous metaplasia of the vulva (MMV) is a histopathologic finding that has been reported previously in only 3 patients and needs to be distinguished from vulvar extramammary Paget disease. We report 3 additional instances of MMV associated to Zoon vulvitis and vulvar lichen sclerosus et atrophicus. Histochemical and immunohistochemical studies were performed on biopsies from erythematous and erosive vulvar lesions of 3 women aged 64, 80 and 84 years, with features of Zoon vulvitis (2 cases) and lichen sclerosus et atrophicus (1 case)...
September 24, 2018: American Journal of Dermatopathology
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