Acute Kidney Injury in Hospitalized Pediatric Patients.

Acute kidney injury (AKI) is pervasive, affecting a significant proportion of critically ill and noncritically ill children. Recent data demonstrate a clear independent association of escalating AKI severity with not only mortality, but also with longer-term disability and chronic kidney disease in children. The paradigm has shifted-patients are no longer dying with AKI, but rather from AKI. In this review, AKI is described in the paradigms of "past," "present," and "future" to stimulate a reassessment of our understanding of this organ dysfunction syndrome. Current treatment strategies as well as novel methodologies are discussed. A global effort is required to make progress in the fight against AKI and improve patient outcomes. [Pediatr Ann. 2018;47(7):e286-e291.].