We have located links that may give you full text access.
Self-rated health, quality of life and appetite as predictors of initiation of dialysis and mortality in patients with chronic kidney disease stages 4-5: a prospective cohort study.
BMC Research Notes 2018 June 9
OBJECTIVE: Patient-reported health status, including symptom burden, functional status and quality of life, are important measures of health in patients with chronic kidney disease. We aimed to investigate patient-reported outcomes (PRO) on self-rated health, appetite, quality of life and their associations with clinical outcomes. We conducted a prospective observational cohort study. Data was collected at baseline using a PRO questionnaire. The primary outcomes were initiation of dialysis, transplantation and mortality. Kaplan-Meier curves and multivariable Cox proportional hazards regression analyses were used.
RESULTS: A total of 126 patients with chronic kidney disease with an eGFR of ≤ 25 mL/min/1.73 m2 were followed for a median of 321 (range 10-523) days. Poor appetite was associated with mortality (hazard ratio 20.9, 95% CI 3.7-129.8). Initiation of dialysis was associated with low self-rated health (hazard ratio 5.2, 95% CI 1.2-24.0). Mean decline in estimated glomerular filtration rate was - 0.9 mL/min/1.73 m2 (95% CI - 1.6 to - 0.2). Decline in self-rated health (p = 0.001) and appetite (p = 0.002) were correlated with reduction in renal function.
RESULTS: A total of 126 patients with chronic kidney disease with an eGFR of ≤ 25 mL/min/1.73 m2 were followed for a median of 321 (range 10-523) days. Poor appetite was associated with mortality (hazard ratio 20.9, 95% CI 3.7-129.8). Initiation of dialysis was associated with low self-rated health (hazard ratio 5.2, 95% CI 1.2-24.0). Mean decline in estimated glomerular filtration rate was - 0.9 mL/min/1.73 m2 (95% CI - 1.6 to - 0.2). Decline in self-rated health (p = 0.001) and appetite (p = 0.002) were correlated with reduction in renal function.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app