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https://www.readbyqxmd.com/read/27894352/immunoassay-of-s-adenosylmethionine-and-s-adenosylhomocysteine-the-methylation-index-as-a-biomarker-for-disease-and-health-status
#1
Xiujuan Hao, Yan Huang, Ming Qiu, Chunlin Yin, Huiming Ren, Hongjie Gan, Huijun Li, Yaxia Zhou, Jiazhi Xia, Wenting Li, Lijuan Guo, Isaac A Angres
BACKGROUND: S-Adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) are relevant to a variety of diseases. Previous reports that quantified SAM and SAH were based on HPLC or LC-MS/MS. No antibody against SAM has been generated, and the antibody against SAH cannot be used with blood samples. Immunoassays have not been used to measure SAM and SAH. In this study, ELISA was used to measure blood SAM and SAH levels. RESULTS: Specific antibodies against SAM were produced for the first time using a stable analog as the antigen...
November 28, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27894335/everolimus-and-exemestane-in-long-survival-hormone-receptor-positive-male-breast-cancer-case-report
#2
Z Ballatore, M Pistelli, N Battelli, A Pagliacci, M De Lisa, R Berardi, S Cascinu
BACKGROUND: Male breast cancer is a rare event, accounting for approximately 1% of all breast carcinomas. Although men with breast cancer had poorer survival when compared with women, data on prognosis principally derive from retrospective studies and from extrapolation of female breast cancer series. We reported the case of a very long survival patient. CASE PRESENTATION: A caucasian 42-year-old man underwent radical mastectomy with axillary dissection for breast cancer in 1993...
November 28, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27894334/how-resilient-is-the-general-population-to-heatwaves-a-knowledge-survey-from-the-enhance-project-in-brussels-and-amsterdam
#3
Joris Adriaan Frank van Loenhout, Debarati Guha-Sapir
BACKGROUND: Studies have shown an increase in mortality and morbidity during heatwaves, especially among the elderly. We assessed the knowledge of the general population of Brussels and Amsterdam on groups at risk and protective measures for heat-related health effects. RESULTS: Six locations with mixed populations were selected in each city. Passer-by's in both cities were asked to participate in a short survey. Respondents in Brussels (n = 120) had significantly more knowledge on risk groups and protective measures than respondents in Amsterdam (n = 133)...
November 28, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27887658/parameter-set-for-computer-assisted-texture-analysis-of-fetal-brain
#4
Hugues Gentillon, Ludomir Stefańczyk, Michał Strzelecki, Maria Respondek-Liberska
BACKGROUND: Magnetic resonance data were collected from a diverse population of gravid women to objectively compare the quality of 1.5-tesla (1.5 T) versus 3-T magnetic resonance imaging of the developing human brain. MaZda and B11 computational-visual cognition tools were used to process 2D images. We proposed a wavelet-based parameter and two novel histogram-based parameters for Fisher texture analysis in three-dimensional space. RESULTS: Wavenhl, focus index, and dispersion index revealed better quality for 3 T...
November 25, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27881182/research-prevalence-of-neural-tube-defects-khartoum-sudan-august-2014-july-2015
#5
Ilham M Omer, Osman M Abdullah, Inaam N Mohammed, Lina A Abbasher
BACKGROUND: Neural tube defects (NTDs) are birth defects that results from failure of the neural tube to develop properly during early pregnancy. METHODS: We studied the prevalence of neural tube defects in newborns admitted to the NICU in Soba University and Omdurman Maternity hospitals, during the period 1st August 2014 to 31st July 2015. A cross-sectional hospital based study, involved all newborns with any type of neural tube defect admitted to the NICU in the study area during the study period...
November 24, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27876085/onychomycosis-in-diabetic-patients-in-fako-division-of-cameroon-prevalence-causative-agents-associated-factors-and-antifungal-sensitivity-patterns
#6
Marvlyn Eba, Anna Longdoh Njunda, Rene Njikam Mouliom, Emmanuel Tebit Kwenti, Anold Nsoh Fuh, Gordon Takop Nchanji, Julius Atashili
BACKGROUND: Onychomycosis is an infection of the nail unit by a fungus. This is a very common infection amongst diabetics. Its occurrence among diabetics in Fako division is unknown. In this study we provide information on the characteristics of onychomycosis in diabetics in Fako division, Cameroon. METHODS: A cross-sectional descriptive and analytical hospital-based study was conducted in two diabetic clinics in the Buea and Limbe regional hospitals. We recruited 152 consenting diabetics into the study...
November 22, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27876076/bladder-outlet-obstruction-a-rare-complication-of-the-neglected-schistosome-schistosoma-haematobium-two-case-reports-and-public-health-challenges
#7
Valirie Ndip Agbor, Tsi Njim, Franklin Ngu Mbolingong
BACKGROUND: Schistosomiasis is a severe parasitic infestation with debilitating complications and is the third most devastating tropical disease in the world. It is one of the neglected tropical diseases (NTDs) with a high disease-burden. We present two rare cases of bladder outlet obstruction: one which led to a chronic kidney disease and ultimately death and a second which recovered after treatment with praziquantel. CASE PRESENTATIONS: A 72 year old male presented with lower urinary tract symptoms which culminated in an episode of acute urinary retention...
November 22, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27871335/aldehyde-dehydrogenase-expression-in-metaphire-posthuma-as-a-bioindicator-to-monitor-heavy-metal-pollution-in-soil
#8
Raju Panday, Padam Shekhar Bhatt, Tribikram Bhattarai, Kumudini Shakya, Lakshmaiah Sreerama
BACKGROUND: Soil contamination and associated pollution plays a detrimental role in soil flora and fauna. Soil is processed and remodeled by subterranean earthworms, accordingly are referred to as soil chemical engineers. These worms, besides processing carbon and nitrogen, serve as minors for processing metals. In heavy metal contaminated soils, they accumulate heavy metals, which in turn cause altered gene expression, including aldehyde dehydrogenase (ALDH) enzymes. This study explores the possibility of ALDH expression in earthworms as a novel biomarker for the heavy metal contamination of soil...
November 21, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27871315/management-of-uterine-rupture-a-case-report-and-review-of-the-literature
#9
Thomas Obinchemti Egbe, Gregory Edie Halle-Ekane, Charlotte Nguefack Tchente, Jacques Ernest Nyemb, Eugene Belley-Priso
BACKGROUND: Maternal morbidity and mortality has been a major World Health Organization concern over the years, especially in sub-Saharan Africa. This paper reports uterine rupture with severe hypovolemic shock managed at the Douala General Hospital, Cameroon. Early clinical diagnosis is paramount to maternal survival. CASE PRESENTATION: Mrs. MM aged 25 years, G3P2012, of the Bamileke tribe in Cameroon was admitted to our Department in hypovolemic shock BP = 70/40 mmHg, pulse 120 beats per minute, with altered consciousness (Glasgow Coma Scale = 13)...
November 21, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27863510/establishing-a-reference-array-for-the-cs-%C3%AE-%C3%AE-superfamily-of-defensive-peptides
#10
D Ellen K Tarr
BACKGROUND: "Invertebrate defensins" belong to the cysteine-stabilized alpha-beta (CS-αβ), also known as the scorpion toxin-like, superfamily. Some other peptides belonging to this superfamily of defensive peptides are indistinguishable from "defensins," but have been assigned other names, making it unclear what, if any, criteria must be met to qualify as an "invertebrate defensin." In addition, there are other groups of defensins in invertebrates and vertebrates that are considered to be evolutionarily unrelated to those in the CS-αβ superfamily...
November 18, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27855718/attitudes-of-dentists-and-interns-in-riyadh-to-the-use-of-dental-amalgam
#11
Fahad Alkhudhairy
BACKGROUND: Studies investigating the attitudes of Saudi dentists to the use of amalgam for restorations are relatively rare. Considering the goals set forth by the Minamata Convention on Mercury, it appears prudent to investigate the attitudes of experienced dentists and fresh dental graduates to the use of amalgam. The aim of this study was to assess the attitudes of Saudi dentists and interns working in Riyadh, Saudi Arabia to the use of amalgam. Using a convenience sampling methodology, a total of 400 Saudi dentists and interns were contacted to request their participation in this cross-sectional questionnaire-based study...
November 17, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27855717/hypertension-control-and-care-at-mulago-hospital-ambulatory-clinic-kampala-uganda
#12
Isaac Ssinabulya, Yvonne Nabunnya, Brian Kiggundu, Charles Musoke, Michael Mungoma, James Kayima
BACKGROUND: Hypertension is as prevalent in many developing countries, as in the developed world and is the leading cause of cardiovascular morbidity and mortality in Africa. The control of hypertension in this resource limited setting is inadequate, a situation that translates into poorer outcomes in form of increasing incidences of stroke, heart failure, kidney failure and therefore early cardiovascular death. METHODS: This was a chart review of all the patients seen during the months of September 2012 to February 2013...
November 17, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27855691/semiautomatic-segmentation-of-the-kidney-in-magnetic-resonance-images-using-unimodal-thresholding
#13
Martin Sandmair, Matthias Hammon, Hannes Seuss, Ragnar Theis, Michael Uder, Rolf Janka
BACKGROUND: Total kidney volume (TKV) is an important marker for the presence or progression of chronic kidney disease, however, routine ultrasonography underestimates renal volume to a high and varying degree. OBJECTIVE: The aim of this work was to adapt and evaluate a semi-automatic unimodal thresholding method for volumetric analysis of the kidney in native T2-weighted magnetic resonance (MR) images. METHODS: In a group of healthy volunteers (n = 24; 48 kidneys), we defined a region of interest (ROI) by manually tracing the outline of the kidney in every MR image...
November 17, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27842574/the-psychiatry-resident-research-experience
#14
Frank P MacMaster, Jordan Cohen, Waqar Waheed, Emilie Magaud, Mariko Sembo, Lisa Marie Langevin, Katherine Rittenbach
BACKGROUND: Research activity is especially critical in the field of psychiatry as it is evolving rapidly thanks to advances in neuroscience. RESULTS: We administered a 34-item survey regarding research experiences targeted at psychiatry residents and postgraduate residency program directors in Canada. One hundred and nineteen participants answered the survey (16 program directors, 103 residents) allowing for a margin of error of 8.4% at a 95% confidence interval...
November 14, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27821143/prevalence-of-mental-distress-and-associated-factors-among-hawassa-university-medical-students-southern-ethiopia-a-cross-sectional-study
#15
Biniam Melese, Birhanu Bayu, Fikir Wondwossen, Kalkidan Tilahun, Seti Lema, Moges Ayehu, Eskindir Loha
BACKGROUND: Mental distress is a mental health problem expressed with variable levels of depressive, anxiety, panic or somatic symptoms. Owing to several factors tertiary level students are among the population with higher prevalence of mental distress and an even more higher prevalence has been reported in medical students. The aim of this study was to determine the prevalence of mental distress among medical students, and to evaluate contextually relevant associated factors. METHODS: A cross-sectional study was conducted among medical students attending Hawassa University College of Medicine and Health Sciences in 2013/2014 academic year...
November 8, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27806729/hematological-reference-intervals-determination-in-adults-at-gondar-university-hospital-northwest-ethiopia
#16
Aregawi Yalew, Betelihem Terefe, Meseret Alem, Bamlaku Enawgaw
BACKGROUND: Hematological reference values are important for the clinical decisions in laboratory diagnosis and monitoring of patients. The correct interpretation of laboratory results depends entirely on the reference intervals that have been established for the locality. But, in sub-Saharan African countries particularly in Ethiopia, locally derived reference intervals were not established and they are forced to use intervals established from western population. Thus this study aimed to establish locally derived hematological reference values that could be used in Northwest Ethiopia...
November 2, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27806727/ear-biometrics-for-patient-identification-in-global-health-a-cross-sectional-study-to-test-the-feasibility-of-a-simplified-algorithm
#17
Elizabeth J Ragan, Courtney Johnson, Jacqueline N Milton, Christopher J Gill
BACKGROUND: One of the greatest public health challenges in low- and middle-income countries (LMICs) is identifying people over time and space. Recent years have seen an explosion of interest in developing electronic approaches to addressing this problem, with mobile technology at the forefront of these efforts. We investigate the possibility of biometrics as a simple, cost-efficient, and portable solution. Common biometrics approaches include fingerprinting, iris scanning and facial recognition, but all are less than ideal due to complexity, infringement on privacy, cost, or portability...
November 2, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27793196/life-expectancy-and-healthy-life-expectancy-of-japan-the-fastest-graying-society-in-the-world
#18
Shinkan Tokudome, Shuji Hashimoto, Akihiro Igata
BACKGROUND: We appraised time trends of Japanese life expectancy (LE) and healthy life expectancy (HALE) by gender, LE-HALE and (LE-HALE)/LE figures, along with the women-men's differences. METHODS: Using the Japanese LE and HALE values from 1990 through 2013 by gender in the article by the GBD 2013 DALYs and HALE Collaborators, we examined trends of LE and HALE, and their 5- or 3-year changes. We also probed LE-HALE and (LE-HALE)/LE values, and the women-men's differences...
October 28, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27782863/knowledge-of-neonatal-danger-signs-among-mothers-attending-well-baby-clinic-in-nakuru-central-district-kenya-cross-sectional-descriptive-study
#19
Elizabeth Gathoni Kibaru, Amos Magembe Otara
BACKGROUND: Neonatal mortality has remained high in Kenya despite various efforts being applied to reduce this negative trend. Early detection of neonatal illness is an important step towards improving new born survival. Toward this end there is need for the mothers to be able to identify signs in neonates that signifies severe neonatal illnesses. The objective of the study was to determine the level of knowledge of mothers attending well baby clinics on postnatal neonatal danger signs and determine the associated factors...
October 25, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27776558/characterization-and-history-of-arterial-hypertension-leading-to-inpatient-treatment
#20
Carsten P Bramlage, Mina Nasiri-Sarvi, Joan Minguet, Peter Bramlage, Gerhard Anton Müller
BACKGROUND AND AIMS: Arterial hypertension is a major cause of death worldwide. For the most part, treatment for hypertension can be performed on an outpatient basis. However, some patients also require inpatient treatment, and the contributing factors for this remain unknown. Therefore, the primary objective of the present study was to determine which patient characteristics are associated with inpatient treatment for arterial hypertension. METHODS: Here, we conducted a mono-centric study of 103 hypertensive subjects, who were treated as inpatients in the Department of Nephrology and rheumatology of the university medical faculty of Göttingen...
October 24, 2016: BMC Research Notes
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