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https://www.readbyqxmd.com/read/28499399/identification-of-potential-campylobacter-jejuni-genes-involved-in-biofilm-formation-by-ez-tn5-transposome-mutagenesis
#1
Amy Huei Teen Teh, Sui Mae Lee, Gary A Dykes
BACKGROUND: Biofilm formation has been suggested to play a role in the survival of Campylobacter jejuni in the environment and contribute to the high incidence of human campylobacteriosis. Molecular studies of biofilm formation by Campylobacter are sparse. RESULTS: We attempted to identify genes that may be involved in biofilm formation in seven C. jejuni strains through construction of mutants using the EZ-Tn5 Transposome system. Only 14 mutants with reduced biofilm formation were obtained, all from one strain of C...
May 12, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28499394/sar1a-promoter-polymorphisms-are-not-associated-with-fetal-hemoglobin-in-patients-with-sickle-cell-disease-from-cameroon
#2
Gift Dineo Pule, Valentina Josiane Ngo Bitoungui, Bernard Chetcha Chemegni, Andre Pascal Kengne, Ambroise Wonkam
BACKGROUND: Reactivation of adult hemoglobin (HbF) is currently a dominant therapeutic approach to sickle cell disease (SCD). In this study, we have investigated among SCD patients from Cameroon, the association of HbF level and variants in the HU-inducible small guanosine triphosphate-binding protein, secretion-associated and RAS-related (SAR1a) protein, previously shown to be associated with HbF after HU treatment in African American SCD patients. RESULTS: Only patients >5 years old were included; hemoglobin electrophoresis and a full blood count were conducted upon arrival at the hospital...
May 12, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28486950/performance-of-mycobacterium-growth-indicator-tube-bactec-960-with-lowenstein-jensen-method-for-diagnosis-of-mycobacterium-tuberculosis-at-ethiopian-national-tuberculosis-reference-laboratory-addis-ababa-ethiopia
#3
Getu Diriba, Abebaw Kebede, Zelalem Yaregal, Muluwork Getahun, Mengistu Tadesse, Abyot Meaza, Zekarias Dagne, Shewki Moga, Jibril Dilebo, Kebebe Gudena, Mulu Hassen, Kassu Desta
BACKGROUND: Bacteriological confirmed active case detection remains the corner stone for diagnosing tuberculosis. Non-radiometric liquid culture system Mycobacterium Growth Indicator Tube with automated interface had been recommended by expert groups in addition to conventional solid culture media such as Lowenstein-Jensen. However in high burden resource limited countries advanced non-radiometric based tuberculosis diagnostic methods such as MGIT 960 is limited. Therefore we have evaluated the performance of MGIT 960 system compared to LJ for recovery of Mycobacterium complex (MTBC) from clinical specimens...
May 10, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28482930/fatal-monomorphic-ventricular-tachycardia-in-a-semi-urban-setting-in-cameroon-a-case-report
#4
Clovis Nkoke, Engelbert Bain Luchuo, Laetitia Dikoume
BACKGROUND: Ventricular tachycardia is a life threatening cardiac arrhythmia. It needs management with defibrillation, without which, immediate death may occur. CASE PRESENTATION: A 66 year old black African patient with a 2 year history of hypertension was admitted to the emergency department of the Buea Regional hospital, a semi-urban setting in Cameroon, after presenting with syncope while in church. The wife described a similar episode 2 weeks prior without any further evaluation...
May 8, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28482929/ivermectin-induced-steven-johnsons-syndrome-case-report
#5
Desmond Aroke, Diego Nitcheu Tchouakam, Alexis Tazinya Awungia, Sylvester Yari Mapoh, Stewart Ndutard Ngassa, Benjamin Momo Kadia
BACKGROUND: Stevens-Johnson syndrome is one of the manifestations of mucocutaneous adverse drug reactions. Although antimicrobials are responsible for greater than 50% of these adverse drug reactions, there is no documented case implicating ivermectin as the culprit. A 38 year old adult Cameroonian male presented to our health facility with facial rash, painful oral sores, black eschars on lips and red tearing eyes 3 days following ingestion of ivermectin received during a nationwide anti-filarial campaign...
May 8, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28482916/estimation-of-single-year-of-age-counts-of-live-births-fetal-losses-abortions-and-pregnant-women-for-counties-of-texas
#6
Bismark Singh, Lauren Ancel Meyers
OBJECTIVES: We provide a methodology for estimating counts of single-year-of-age live-births, fetal-losses, abortions, and pregnant women from aggregated age-group counts. As a case study, we estimate counts for the 254 counties of Texas for the year 2010. RESULTS: We use interpolation to estimate counts of live-births, fetal-losses, and abortions by women of each single-year-of-age for all Texas counties. We then use these counts to estimate the numbers of pregnant women for each single-year-of-age, which were previously available only in aggregate...
May 8, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28476145/disseminated-bacillus-calmette-gu%C3%A3-rin-bcg-infections-in-infants-with-immunodeficiency
#7
Suleiman Al-Hammadi, Ahmed R Alsuwaidi, Eman T Alshamsi, Ghassan A Ghatasheh, Abdul-Kader Souid
BACKGROUND: The Bacillus Calmette-Guérin (BCG) preparations are live-attenuated derivatives of Mycobacterium bovis. These products are used to vaccinate infants at birth, a practice that may result in a disseminated infection in those patients who have an unidentified immunodeficiency. CASE PRESENTATION: Patients who were immunized at birth with BCG and who developed a disseminated infection are reported here to emphasize the importance of taking an extensive medical history before ‎giving the BCG vaccine...
May 5, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28464957/association-between-objectively-evaluated-physical-activity-and-sedentary-behavior-and-screen-time-in-primary-school-children
#8
Chiaki Tanaka, Maki Tanaka, Masayuki Okuda, Shigeru Inoue, Tomoko Aoyama, Shigeho Tanaka
BACKGROUND: Even when meeting guidelines for physical activity (PA), considerable sedentary time may be included. This study in primary school children investigated the relationships between objectively evaluated sedentary and PA times at different intensities using triaxial accelerometry that discriminated between ambulatory and non-ambulatory PA. The relationships between subjectively evaluated screen time (i.e. time spent viewing television and videos, playing electronic games, and using personal computers) and objectively evaluated sedentary and PA times were examined...
May 2, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28464913/prevalence-of-hyperglycaemia-first-detected-during-pregnancy-and-subsequent-obstetric-outcomes-at-st-francis-hospital-nsambya
#9
Betty Nakabuye, Silver Bahendeka, Romano Byaruhanga
BACKGROUND: Women with hyperglycaemia detected during pregnancy are at greater risk for adverse pregnancy outcomes. Data on hyperglycaemia in pregnancy in sub-Saharan Africa is scanty and varied depending on the populations studied and the methodologies used to define hyperglycaemia in pregnancy. With the recent 2013 World Health Organisation (WHO) diagnostic criteria and classification, there is yet no sufficient data on the prevalence of hyperglycaemia in sub-Saharan Africa. The objective was to determine the prevalence of Hyperglycaemia first detected during pregnancy and subsequent obstetric outcomes among patients attending antenatal care (ANC) at St...
May 2, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28464902/students-helping-students-vertical-peer-mentoring-to-enhance-the-medical-school-experience
#10
Christine Andre, Jessica Deerin, Luci Leykum
BACKGROUND: Effective mentoring is an important component of medical student professional development. We provide a description of the mentoring program at our institution. METHODS: Our institution UTHSCSA implemented a student-advising program (Veritas) with clinical faculty mentors and senior students (MiMs). The MiMs provided vertical peer mentoring to more junior students as an adjunct to faculty advising. The MiMs lead small group discussions that foster camaraderie, share academic and career information and promote professional identity...
May 2, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28454589/prevalence-and-antimicrobial-resistance-profile-of-staphylococcus-in-dairy-farms-abattoir-and-humans-in-addis-ababa-ethiopia
#11
Takele Beyene, Halefom Hayishe, Fikru Gizaw, Ashenafi Feyisa Beyi, Fufa Abunna, Bedaso Mammo, Dinka Ayana, Hika Waktole, Reta Duguma Abdi
BACKGROUND: Staphylococcus species cause mastitis and wound infection in livestock and food poisoning in humans through ingestion of contaminated foods, including meat and dairy products. They are evolving pathogens in that they readily acquire drug resistance, and multiple drug-resistant (MDR) isolates are increasing in human and veterinary healthcare. Therefore, this study was conducted to evaluate the prevalence of Staphylococci and their drug resistance in dairy farms and abattoir settings of Addis Ababa...
April 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28454556/molecular-and-epidemiological-characterization-of-hiv-1-subtypes-among-libyan-patients
#12
Mohamed A Daw, Abdallah El-Bouzedi, Mohamed O Ahmed, Aghnyia A Dau
BACKGROUND: The epidemiological and clinical aspects of human immunodeficiency virus subtypes are of great interest worldwide. These subtypes are rarely studied in North African countries. Libya is a large country with the longest coast on the Mediterranean Sea, facing the Southern European countries. Studies on the characterization of HIV-1 subtypes are limited in Libya. This study aimed to determine the magnitude of the HIV problem among the Libyan population and to better understand the genetic diversity and the epidemiologic dynamics of HIV 1, as well as to correlate that with the risk factors involved...
April 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28454552/how-common-is-ponticulus-posticus-on-lateral-cephalograms
#13
Jamal Giri, Prabhat Ranjan Pokharel, Rajesh Gyawali
BACKGROUND: Ponticulus posticus is an anomaly of first cervical vertebra visible on lateral cephalogram and has some serious medical and surgical implications. Unfortunately, it is often overlooked or undetected by orthodontists. The general objective of this study is to sensitize orthodontists about this anomaly by depicting its prevalence among a group of Nepalese orthodontic patients. METHODS: Four hundred and fourteen digital lateral cephalograms of orthodontic patients were retrieved from the archives of the department...
April 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28454550/occupational-factors-and-low-back-pain-a-cross-sectional-study-of-bangladeshi-female-nurses
#14
Shubrandu S Sanjoy, Gias U Ahsan, Hayatun Nabi, Ziaul F Joy, Ahmed Hossain
BACKGROUND: The suffering from low back pain (LBP) is very common among nurses. The high prevalence rates of LBP are observed in many countries. Many back injuries are due to individual and work-related factors. Our aim is to investigate whether there is an association of occupational factors with LBP among the female nurses who are currently working in tertiary hospitals of Bangladesh. METHODS: We conducted a cross-sectional study with 229 female nurses from two selected tertiary hospitals in Bangladesh...
April 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28446247/difference-in-oxidative-stress-tolerance-between-rice-cultivars-estimated-with-chlorophyll-fluorescence-analysis
#15
Ichiro Kasajima
BACKGROUND: Oxidative stress is considered to be involved in growth retardation of plants when they are exposed to a variety of biotic and abiotic stresses. Despite its potential importance in improving crop production, comparative studies on oxidative stress tolerance between rice (Oryza sativa L.) cultivars are limited. This work describes the difference in term of oxidative stress tolerance between 72 rice cultivars. METHODS: 72 rice cultivars grown under naturally lit greenhouse were used in this study...
April 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28446246/the-role-of-rk39-serologic-test-in-the-diagnosis-of-visceral-leishmaniasis-in-a-tertiary-hospital-northern-ethiopia
#16
Yazezew Kebede Kiros, Bethlhem Feleke Regassa
BACKGROUND: The study is done in Ayder Referral Hospital in Northern Ethiopia. Ethiopia is one of the countries where visceral leishmaniasis (VL) is endemic. Diagnosis of VL in Ethiopia is primarily based on rK39 immunochromatographic (rk39-ICT) strip. This test has been shown to have variable sensitivity and specificity in different countries. Hence the objective of the study is to determine the sensitivity and specificity of rk39-ICT in the diagnosis of VL in our set up. The study participants were VL suspected patients admitted to the hospital...
April 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28446211/spontaneous-migraine-attack-causes-alterations-in-default-mode-network-connectivity-a-resting-state-fmri-case-report
#17
Andrea Edit Edes, Lajos Rudolf Kozak, Mate Magyar, Terezia Zsombok, Gyongyi Kokonyei, Gyorgy Bagdy, Gabriella Juhasz
BACKGROUND: Although migraine is one of the most investigated neurologic disorders, we do not have a perfect neuroimaging biomarker for its pathophysiology. One option to improve our knowledge is to study resting-state functional connectivity in and out of headache pain. However, our understanding of the functional connectivity changes during spontaneous migraine attack is partial and incomplete. CASE PRESENTATION: Using resting-state functional magnetic resonance imaging we assessed a 24-year old woman affected by migraine without aura at two different times: during a spontaneous migraine attack and in interictal phase...
April 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28446210/cognitive-changes-in-alcohol-induced-psychotic-disorder
#18
Melany L Hendricks, R A Emsley, D G Nel, H B Thornton, G P Jordaan
AIMS: This study aimed to explore the neuro-cognitive deficits of alcohol-induced psychotic disorder as compared to the cognitive deficits of uncomplicated alcohol dependence. METHODS: Participants were recruited from the acute psychiatric admission wards of the Department of Psychiatry, University of Stellenbosch and Stikland and Tygerberg Academic Hospitals in the Western-Cape, South Africa. Participants who met DSM IV TR criteria (American Psychiatric Association...
April 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28446201/anticonvulsant-effects-of-antiaris-toxicaria-aqueous-extract-investigation-using-animal-models-of-temporal-lobe-epilepsy
#19
Priscilla Kolibea Mante, Donatus Wewura Adongo, Eric Woode
BACKGROUND: Antiaris toxicaria has previously shown anticonvulsant activity in acute animal models of epilepsy. The aqueous extract (AAE) was further investigated for activity in kindling with pentylenetetrazole and administration of pilocarpine and kainic acid which mimic temporal lobe epilepsy in various animal species. RESULTS: ICR mice and Sprague-Dawley rats were pre-treated with AAE (200-800 mg kg(-1)) and convulsive episodes induced using pentylenetetrazole, pilocarpine and kainic acid...
April 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28441972/efficacy-of-olmesartan-amlodipine-in-colombian-hypertensive-patients-soat-study
#20
Richard Buendia, Monica Zambrano
BACKGROUND: Emerging evidence has shown a significant deficit in the control of hypertension (blood pressure <140/90 mmHg) among Hispanics or Latinos in about 65%. This study aims to determine the efficacy of the combination in fixed doses of olmesartan and amlodipine (20/5, 40/5, and 40/10 mg) in hypertensive patients treated in daily clinical practice by Colombian doctors. METHODS: This was an observational, retrospective, open-label, multi-center, non-comparative study...
April 26, 2017: BMC Research Notes
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