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BMC Research Notes

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https://www.readbyqxmd.com/read/28235422/crying-spells-triggered-by-thumb-index-rubbing-after-thalamic-stroke-a-case-report
#1
R Bassani, C Rosazza, L Ghirardin, V Caldiera, E Banco, C Casati, L Tesio
BACKGROUND: Pathologic crying, devoid of any emotional counterpart, is known to occur as a consequence of various brain stem, cortical hemispheric and cerebellar lesions or, quite exceptionally, of "dacrystic" epilepsy. The case reported here suggests that thalamic lesions may also cause crying spells, under the special circumstances described below. CASE PRESENTATION: After a mild left thalamic stroke a caucasian 77 years old man presented with crying spells with no emotional counterpart, triggered by thumb-index rubbing of his right hand...
February 24, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28235420/altered-expression-profiles-of-microrna-families-during-de-etiolation-of-maize-and-rice-leaves
#2
Jiajia Xu, Yuanyuan Li, Yaling Wang, Xinyu Liu, Xin-Guang Zhu
BACKGROUND: MicroRNAs (miRNAs) are highly conserved small non-coding RNAs that play important regulatory roles in plants. Although many miRNA families are sequentially and functionally conserved across plant kingdoms (Dezulian et al. in Genome Biol 13, 2005), they still differ in many aspects such as family size, average length, genomic loci etc. (Unver et al. in Int J Plant Genomics, 2009). RESULTS: In this study, we investigated changes of miRNA expression profiles during greening process of etiolated seedlings of Oryza sativa (C3) and Zea mays (C4) to explore conserved and species-specific characteristics of miRNAs between these two species...
February 24, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28235417/accuracy-of-glomerular-filtration-rate-equations-for-chronic-kidney-disease-patients-at-the-g3a-stage-a-single-center-cross-sectional-study
#3
Yanna Dou, Xiran Sun, Dong Liu, Li Zhang, Jing Xiao, Genyang Cheng, Dahai Yu, Zhanzheng Zhao
BACKGROUND: Kidney disease improving global outcomes provided a new classification for chronic kidney disease (CKD) by subdividing the G3 stage into G3a and G3b stages based on glomerular filtration rate (GFR) in 2012. Currently, a few methods are used to evaluate GFR, including measured GFR (mGFR) and estimated GFR (eGFR). One of the mGFR was (99m)Tc-DTPA scintigraphy method and eGFR using GFR equations were used clinically. Equations were modification of diet in renal disease (MDRD), chronic kidney disease epidemiology collaboration (CKD-EPI), and Chinese adapted MDRD (C-MDRD)...
February 24, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28231812/incidence-of-macrolide-lincosamide-streptogramin-b-resistance-amongst-beta-haemolytic-streptococci-in-the-gambia
#4
Ebenezer Foster-Nyarko, Brenda Kwambana, Fatima Ceesay, Kaddijatou Jawneh, Saffiatou Darboe, Sarah N Mulwa, Buntung Ceesay, Ousman O Secka, Ifedayo Adetifa, Martin Antonio
BACKGROUND: In West Africa, penicillin, macrolide and lincosamide resistance among beta-haemolytic streptococci (BHS) isolates has rarely been described. However, such data are critical to detect and track the emergence of antibiotic resistance. METHODS: Beta-haemolytic streptococci were cultured from clinical specimens from patients attending the clinic at the Medical Research Council Unit The Gambia (n = 217) and kept at -70 °C. Of these, 186 were revived and tested for penicillin susceptibility by disc diffusion and E-test methods, and the D-test for determination of constitutive and inducible macrolide-lincosamide (MLSB) resistance phenotypes...
February 23, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28222763/the-discovery-of-novel-lpmo-families-with-a-new-hidden-markov-model
#5
Gerben P Voshol, Erik Vijgenboom, Peter J Punt
BACKGROUND: Renewable biopolymers, such as cellulose, starch and chitin are highly resistance to enzymatic degradation. Therefore, there is a need to upgrade current degradation processes by including novel enzymes. Lytic polysaccharide mono-oxygenases (LPMOs) can disrupt recalcitrant biopolymers, thereby enhancing hydrolysis by conventional enzymes. However, novel LPMO families are difficult to identify using existing methods. Therefore, we developed a novel profile Hidden Markov model (HMM) and used it to mine genomes of ascomycetous fungi for novel LPMOs...
February 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28219451/quantitative-morphological-analysis-of-2d-images-of-complex-shaped-branching-biological-growth-forms-the-example-of-branching-thalli-of-liverworts
#6
Pirom Konglerd, Catherine Reeb, Fredrik Jansson, Jaap A Kaandorp
BACKGROUND: Many organisms such as plants can be characterized as complex-shaped branching forms. The morphological quantification of the forms is a support for a number of areas such as the effects of environmental factors and species discrimination. To date, there is no software package suitable for our dataset representing the forms. We therefore formulate methods for extracting morphological measurements from images of the forms. RESULTS: As a case study we analyze two-dimensional images of samples from four groups belonging to three species of thalloid liverworts, genus Riccardia...
February 20, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28219448/a-computational-protocol-to-evaluate-the-effects-of-protein-mutants-in-the-kinase-gatekeeper-position-on-the-binding-of-atp-substrate-analogues
#7
Valentina Romano, Tjaart A P de Beer, Torsten Schwede
BACKGROUND: The determination of specific kinase substrates in vivo is challenging due to the large number of protein kinases in cells, their substrate specificity overlap, and the lack of highly specific inhibitors. In the late 90s, Shokat and coworkers developed a protein engineering-based method addressing the question of identification of substrates of protein kinases. The approach was based on the mutagenesis of the gatekeeper residue within the binding site of a protein kinase to change the co-substrate specificity from ATP to ATP analogues...
February 20, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28212682/erratum-to-cause-effect-relations-between-55%C3%A2-kd-soluble-tnf-receptor-concentrations-and-specific-and-unspecific-symptoms-in-a-patient-with-mild-sle-disease-activity-an-exploratory-time-series-analysis-study
#8
Christian Schubert, Julia Haberkorn, Francisco M Ocaña-Peinado, Paul König, Norbert Sepp, Mirjam Schnapka-Köpf, Dietmar Fuchs
No abstract text is available yet for this article.
February 17, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28212665/clinical-outcome-of-periodontal-regenerative-therapy-using-collagen-membrane-and-deproteinized-bovine-bone-mineral-a-2-5-year-follow-up-study
#9
Daisuke Irokawa, Takahiro Takeuchi, Katsuya Noda, Hiroaki Goto, Masahiro Egawa, Sachiyo Tomita, Hiroki Sugito, Masahiko Nikaido, Atsushi Saito
BACKGROUND: This study aimed to evaluate, longitudinally, the outcome of periodontal regenerative therapy using a deproteinized bovine bone mineral (DBBM) in combination with a collagen barrier (CB) for the treatment of intrabony defects. RESULTS: Patients with chronic periodontitis who have completed initial periodontal therapy participated in this study. They had at least one 2- or 3-wall intrabony periodontal defect of ≥3 mm in depth. During surgery, defects were filled with DBBM and covered with CB...
February 17, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28209187/perceptions-and-experiences-of-pregnant-women-about-routine-hiv-testing-and-counselling-in-ghimbi-town-ethiopia-a-qualitative-study
#10
Israel Mitiku, Adamu Addissie, Mitike Molla
BACKGROUND: Ethiopia has implemented routine HIV testing and counselling using a provider initiated HIV testing ('opt-out' approach) to achieve high coverage of testing and prevention of mother-to-child transmission of HIV. However, women's perceptions and experiences with this approach have not been well studied. We conducted a qualitative study to explore pregnant women's perceptions and experiences of routine HIV testing and counselling in Ghimbi town, Ethiopia, in May 2013. In-depth interviews were held with 28 women tested for HIV at antenatal clinics (ANC), as well as four health workers involved in routine HIV testing and counselling...
February 16, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28202083/detecting-differential-gene-expression-in-blastocysts-following-pronuclear-transfer
#11
LETTER
Edward H Morrow, Fiona C Ingleby
Nuclear transfer techniques (a.k.a. mitochondrial replacement therapies) are currently under development to provide a route to eliminating particular instances of mitochondrial disease from the germline. Before these kinds of techniques are implemented clinically it is of primary concern that their safety and efficacy is established. In a recent paper, Hyslop et al. (Nature 534:383-386, 2016. doi: 10.1038/nature18303 ) utilized a specific version of pronuclear transfer to investigate the consequences for gene expression in the developing embryo, which may indicate whether or not developmental pathways have been perturbed...
February 15, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28202077/repellent-effects-of-the-essential-oils-of-cymbopogon-citratus-and-tagetes-minuta-on-the-sandfly-phlebotomus-duboscqi
#12
Albert Kimutai, Moses Ngeiywa, Margaret Mulaa, Peter G N Njagi, Johnstone Ingonga, Lydia B Nyamwamu, Cyprian Ombati, Philip Ngumbi
BACKGROUND: The sandfly, Phlebotomus duboscqi is a vector of zoonotic cutaneous leishmaniasis (ZCL) that is an important public health problem in Eastern Africa. Repellents have been used for protection of humans against vectors of ZCL and other vectors that transmit killer diseases including malaria, Rift Valley fever, dengue, and yellow fever. The repellent effects of different doses of the essential oils from the lemon grass, Cymbopogon citratus and Mexican marigold, Tagetes minuta were evaluated in a two-chamber bioassay against 3- to 7-day-old unfed females of P...
February 15, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28202069/prevalence-of-cardiovascular-morbidities-in-myanmar
#13
Ko Ko Zaw, Nwe Nwe, Su Su Hlaing
BACKGROUND: Cardiovascular diseases (CVDs) are now in a rising trend in South East Asia including Myanmar due to increase in major cardiovascular risk factors in both urban and rural areas, such as smoking, obesity and diabetes mellitus. It is necessary to determine CVD morbidities in Myanmar for planning of prevention and control activities for CVDs. The cross-sectional household survey was conducted in 2012 with 600 people aged 40 years and above in four townships (Kyauk-Tan, Mawlamyaing, Pathein and Pyay) and used face-to-face interview with standard questionnaire [Rose Angina Questionnaire and Questionnaire by European Cardiovascular Indicators Surveillance Set (EUROCISS) Research Group] to determine the level of reported CVD morbidities in adult population...
February 15, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28193251/digital-chest-x-ray-through-a-mobile-van-public-private-partnership-to-detect-sputum-negative-pulmonary-tb
#14
LETTER
Bornali Datta, Anupama Hazarika, Hemant Deepak Shewade, Kavita Ayyagari, Ajay M V Kumar
Nearly half of the smear negative pulmonary TB in National TB Programme remain undetected in Haryana (north Indian state), probably due to poor access to chest radiography. A corporate hospital stepped into fill this infrastructure gap in Rewari district of Haryana by sending a mobile van with digital x-ray facilities and paramedic staff. The staff of the public health facility coordinated with the eligible patients and ensured that they visited on the designated day. The District TB Officer interpreted the x-ray and made decisions about diagnosis and treatment...
February 14, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28193243/bite-size-research-bmc-research-notes-goes-back-to-its-roots
#15
EDITORIAL
Dirk Krüger, Diana M Marshall
Since it first launched in 2008, BMC Research Notes has been a place where researchers can publish short notes and observations, research outputs which are useful for the community but which can end up hidden in the lab notebook or as a footnote in a dataset. In order to re-affirm the importance of publishing these kinds of outputs, the journal is renewing its focus on publishing note articles as well as other potentially dark data such as short null results. Publishing these articles is useful for many researchers, therefore we are also expanding the scope to all scientific and clinical disciplines including health sciences, life sciences, physical sciences, mathematics and all engineering disciplines...
February 14, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28193287/a-comparison-of-stress-levels-coping-styles-and-psychological-morbidity-between-graduate-entry-and-traditional-undergraduate-medical-students-during-the-first-2%C3%A2-years-at-a-uk-medical-school
#16
R Zvauya, F Oyebode, E J Day, C P Thomas, L A Jones
BACKGROUND: Stress levels and psychological morbidity are high among undergraduate medical students (UGs), but there is a lack of research into the psychological health of UK graduate-entry medical students (GEs). GEs are likely to experience different (perhaps more severe) stressors and to cope with stress differently. We compared stress levels, psychological morbidity and coping styles in GE versus UG medical students studying at the same UK medical school in the same academic year...
February 13, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28193286/tropical-diabetic-hand-syndrome-a-case-report
#17
Eugene Vernyuy Yeika, Jacques Cabral Tchoumi Tantchou, Joyce Bei Foryoung, Paul Nkemtendong Tolefac, Derrick Tembi Efie, Siméon Pierre Choukem
BACKGROUND: Tropical diabetic hand syndrome describes a complex hand sepsis affecting patients with diabetes across the tropics and often results from a trivial hand trauma. The clinical presentation of this syndrome is variable and ranges from localised swelling and cellulitis, with or without ulceration of the hand to progressive fulminant hand sepsis, and gangrene affecting the entire limb which may be fatal. Tropical diabetic hand syndrome could lead to permanent disability and death as a result of delay in presentation, late diagnosis and late medical and surgical intervention...
February 13, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28187779/bio-efficacy-of-deltamethrin-based-durable-wall-lining-against-wild-populations-of-anopheles-gambiae-s-l-in-northern-tanzania
#18
Eliningaya J Kweka, Ming-Chieh Lee, Beda J Mwang'onde, Filemoni Tenu, Stephen Munga, Epiphania E Kimaro, Yousif E Himeidan
BACKGROUND: Indoor residual spraying (IRS) is one of the preferred tools used for control of malaria in many settings in the world. However, this control tool still faces challenges that include lack of long lasting active ingredient, limited number of well-trained personal, and need of repeated treatment which increases operational costs and reduces acceptability by residents. As a result there is need to develop and validate other methods which can complement the existing controls. The current study compared the bio-efficacy of durable wall lining (DL) (treated with deltamethrin 265 mg/m(2)) and IRS (with deltamethrin 5% WP at 20 mg/m(2)) on indoor mosquitoes densities and biting behaviour of mosquitoes in comparison with control houses without either DL or IRS...
February 10, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28187776/mycobacterium-bovis-in-a-european-bison-bison-bonasus-raises-concerns-about-tuberculosis-in-brazilian-captive-wildlife-populations-a-case-report
#19
Cristina Kraemer Zimpel, Juliana Sperotto Brum, Antônio Francisco de Souza Filho, Alexander Welker Biondo, João Henrique Perotta, Cristina Corsi Dib, Marcelo Bonat, José Soares Ferreira Neto, Paulo Eduardo Brandão, Marcos Bryan Heinemann, Ana Marcia Sa Guimaraes
BACKGROUND: Tuberculosis caused by Mycobacterium bovis is an important worldwide zoonosis and has been reported to cause clinical disease in several animal species, including captive wildlife. This report describes a case of M. bovis infection in a European bison from a Brazilian zoo and compiles a number of literature reports that raise concern regarding tuberculosis among captive wildlife in Brazil. CASE PRESENTATION: A 13 year-old captive-born male bison (Bison bonasus) from a Brazilian zoo began presenting weight loss, diarrhea and respiratory symptoms, which inevitably led to his death...
February 10, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28183341/assessing-the-feasibility-of-ehealth-and-mhealth-a-systematic-review-and-analysis-of-initiatives-implemented-in-kenya
#20
REVIEW
Martin Njoroge, Dejan Zurovac, Esther A A Ogara, Jane Chuma, Doris Kirigia
BACKGROUND: The growth of Information and Communication Technology in Kenya has facilitated implementation of a large number of eHealth projects in a bid to cost-effectively address health and health system challenges. This systematic review aims to provide a situational analysis of eHealth initiatives being implemented in Kenya, including an assessment of the areas of focus and geographic distribution of the health projects. The search strategy involved peer and non-peer reviewed sources of relevant information relating to projects under implementation in Kenya...
February 10, 2017: BMC Research Notes
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