journal
https://read.qxmd.com/read/38539217/an-in-silico-analysis-of-ogt-gene-association-with-diabetes-mellitus
#1
JOURNAL ARTICLE
Abigail O Ayodele, Brenda Udosen, Olugbenga O Oluwagbemi, Elijah K Oladipo, Idowu Omotuyi, Itunuoluwa Isewon, Oyekanmi Nash, Opeyemi Soremekun, Segun Fatumo
O-GlcNAcylation is a nutrient-sensing post-translational modification process. This cycling process involves two primary proteins: the O-linked N-acetylglucosamine transferase (OGT) catalysing the addition, and the glycoside hydrolase OGA (O-GlcNAcase) catalysing the removal of the O-GlCNAc moiety on nucleocytoplasmic proteins. This process is necessary for various critical cellular functions. The O-linked N-acetylglucosamine transferase (OGT) gene produces the OGT protein. Several studies have shown the overexpression of this protein to have biological implications in metabolic diseases like cancer and diabetes mellitus (DM)...
March 27, 2024: BMC Research Notes
https://read.qxmd.com/read/38532408/heterogeneity-of-clinical-symptomatology-in-pediatric-patients-at-clinical-high-risk-for-psychosis
#2
JOURNAL ARTICLE
L Sophia Rintell, Devon Carroll, Meghan Wales, Joseph Gonzalez-Heydrich, Eugene D'Angelo
OBJECTIVE: Widespread use of diagnostic tools like the Structured Interview for Prodromal Symptoms (SIPS) has highlighted that youth at Clinical High Risk for Psychosis (CHR-P) present with heterogeneous symptomatology. This pilot study aims to highlight the range of clinical characteristics of CHR-P youth, investigate the role of the non-positive (negative, disorganization, and general) symptoms in risk assessment, and determine if specific profiles are associated with severe symptomatology...
March 26, 2024: BMC Research Notes
https://read.qxmd.com/read/38515162/zika-virus-prevention-behaviors-and-knowledge-among-male-partners-of-pregnant-people-and-lack-of-condom-use-as-a-prevention-behavior-from-the-zika-en-embarazadas-y-ni%C3%A3-os-zen-prospective-cohort-study-colombia
#3
JOURNAL ARTICLE
Christina L Sancken, Ayzsa Tannis, Sandra A Amouzou, Veronica Burkel, Jeffrey M Carlson, Suzanne Newton, Suzanne M Gilboa, Maritza Gonzalez, Diana Valencia, Van T Tong, Martha Ospina
OBJECTIVE: Zika virus (ZIKV) infection in pregnancy can cause brain and eye abnormalities and neurodevelopmental sequelae. In the absence of medical countermeasures, behavioral interventions were recommended to prevent mosquito bites and sexual transmission of ZIKV. This report uses data from the Zika en Embarazadas y Niños (ZEN) prospective cohort study in Colombia to describe the knowledge, attitudes, and behaviors (KAB) related to ZIKV prevention in male partners compared to those of their pregnant partners at study enrollment during February 2017-2018...
March 21, 2024: BMC Research Notes
https://read.qxmd.com/read/38509599/long-term-outcome-of-combined-radiologic-and-surgical-strategy-for-the-management-of-biliary-complications-after-pediatric-liver-transplantation
#4
JOURNAL ARTICLE
Ana M Calinescu, Sébastien Monluc, Stephanie Franchi-Abella, Dalila Habes, Gabrielle Weber, Marion F Almes, Jerome Waguet, Emmanuel Jacquemin, Virginie Fouquet, Jordi Miatello, Geraldine Hery, Catherine Baujard, Emmanuel Gonzales, Sophie Branchereau, Florent Guérin
OBJECTIVES: We aimed to analyze the risk factors for management failure of BC after pediatric liver transplantation (pLT) by retrospectively analyzing primary pLT performed between 1997 and 2018 (n = 620 patients). RESULTS: In all, 117/620 patients (19%) developed BC. The median (range) follow-up was 9 (1.4-21) years. Patient survival at 1, 5 and 10 years was 88.9%, 85.7%, 84.4% and liver graft survival was 82.4%, 77.4%, and 74.3% respectively...
March 20, 2024: BMC Research Notes
https://read.qxmd.com/read/38504380/a-gender-specific-geodatabase-of-five-cancer-types-with-the-highest-frequency-of-occurrence-in-iran
#5
JOURNAL ARTICLE
Sharareh Faramarzi, Behzad Kiani, Mohammedreza Hoseinkhani, Neda Firouraghi
OBJECTIVES: Cancer is a global health challenge with complex characteristics. Despite progress in research and treatment, a universally effective prevention strategy is lacking. Access to reliable information, especially on occurrence rates, is vital for cancer management. This study aims to create a database containing individual and spatially integrated data on commonly diagnosed cancers in Iran from 2014 to 2017, serving as a valuable resource for spatial-epidemiological approaches...
March 19, 2024: BMC Research Notes
https://read.qxmd.com/read/38504371/lipopolysaccharide-regulation-of-antiinflammatory-tristetraprolin-family-and-proinflammatory-gene-expression-in-mouse-macrophages
#6
JOURNAL ARTICLE
Heping Cao
OBJECTIVE: Tristetraprolin (TTP/ZFP36) family proteins exhibit antiinflammatory effects by destabilizing proinflammatory mRNAs. Previous studies showed that bacterial endotoxin lipopolysaccharides (LPS) stimulated TTP and tumor necrosis factor (TNF) gene expression, but less was known about LPS effects on TTP homologues and other proinflammatory gene expression in macrophages. The objective was to investigate LPS regulation of TTP family gene and TTP-targeted gene expression in mouse RAW264...
March 19, 2024: BMC Research Notes
https://read.qxmd.com/read/38504326/time-course-of-balance-training-related-changes-on-static-and-dynamic-balance-performance-in-healthy-children
#7
JOURNAL ARTICLE
Thomas Muehlbauer, Michael Giesen, Nele Roß, Simon Schedler, Mathew W Hill
OBJECTIVE: In healthy children, there is evidence of improvements in static and dynamic balance performance following balance training. However, the time-course of balance training-related changes is unknown. Thus, we determined the effects of balance training after one, three, and six weeks of exercise on measures of static and dynamic balance in healthy children (N = 44, 20 females, mean age: 9.6 ± 0.5 years, age range: 9-11 years). RESULTS: Participants in the intervention group (2 × 25 min balance exercises per week) compared to those in the control group (2 × 25 min track and field exercises and soccer practice per week) significantly improved their static (i...
March 19, 2024: BMC Research Notes
https://read.qxmd.com/read/38504305/determine-the-factors-affecting-the-time-to-recovery-of-children-with-bacterial-meningitis-at-jigjiga-university-referral-hospital-in-the-somali-regional-state-of-ethiopia-using-the-parametric-shared-frailty-and-aft-models
#8
JOURNAL ARTICLE
Daud Hussein Adawe, Dagne Tesfaye Mengistie
BACKGROUND: Neisseria meningitides, Streptococcus pneumonia, and hemophilic influenza type B are frequently linked to bacterial meningitis (BM) in children. It's an infectious sickness that kills and severely mobilizes children. For a variety of reasons, bacterial meningitis remains a global public health concern; most cases and deaths are found in Sub-Saharan Africa, particularly in Ethiopia. Even though vaccination has made BM more preventable, children worldwide are still severely harmed by this serious illness...
March 19, 2024: BMC Research Notes
https://read.qxmd.com/read/38504304/factors-associated-with-vaccine-hesitancy-against-covid-19-among-adults-in-europe-a-descriptive-study-analysis-applying-socio-ecological-framework
#9
JOURNAL ARTICLE
Megumi Nagase
OBJECTIVE: This study aimed to explore the factors associated with COVID-19 vaccine hesitancy in Europe among adults by using the Socio-Ecological Model. RESULTS: This cross-sectional study used secondary data collected from respondents residing in 27 EU countries at the time of May 2021. The outcome was vaccine hesitancy against COVID-19, and the total sample size of 23,606 was analysed by binary logistic regression, as well as McKelvey and Zavonoia's R2 . After adding each level of variables, the model found the significant and increased association with vaccine hesitancy in younger age groups (21-39 years and 40-60 years vs...
March 19, 2024: BMC Research Notes
https://read.qxmd.com/read/38500215/digital-design-of-a-hybrid-bone-and-tooth-supported-surgical-guide-in-patients-with-unilateral-few-remaining-natural-teeth-a-dental-technique
#10
JOURNAL ARTICLE
Medhat Sameh Abdelaziz, Esraa M Elshikh
A technique for the design of a hybrid tooth and bone-supported implant drilling guide is described. The patient was scanned using cone beam computed tomography and an optical intraoral scanner. The dicom file was segmented according to the area of interest composed of bone and the remaining natural teeth. The Standard Tessellation Language (STL) file was trimmed to only the teeth providing support, followed by merging between the bone and teeth files in one STL. The implant drilling guide was designed with the Real Guide software program, and the file was 3-dimensionally printed in clear surgical guide resin...
March 18, 2024: BMC Research Notes
https://read.qxmd.com/read/38486311/correction-ukumela-impilo-randomised-trial-preliminary-findings-of-height-adjustable-sit-to-stand-workstations-on-health-outcomes-of-south-african-office-workers
#11
Merling Phaswana, Philippe Jean-Luc Gradidge
No abstract text is available yet for this article.
March 14, 2024: BMC Research Notes
https://read.qxmd.com/read/38486302/correction-challenges-and-solutions-to-recruitment-of-neonates-and-children-having-cardiac-surgery-into-a-study-using-a-novel-sampling-device
#12
Terrie Walker-Smith, Daniel Fudulu, Aravind Ramesh, Karen Sheehan, Julie Madden, Lucy Culliford, Jonathan Evans, Gianni D Angelini, Thomas Upton, Ben Gibbison
No abstract text is available yet for this article.
March 14, 2024: BMC Research Notes
https://read.qxmd.com/read/38486279/sox9-downregulation-in-non-obstructive-azoospermia-by-utf1-and-mediator-role-of-pou5f1
#13
JOURNAL ARTICLE
Mehdi Mehdinezhad Roshan, Hossein Azizi, Mohammadreza Ashtari Majelan, Amirreza Niazi Tabar
BACKGROUND: Spermatogenesis is the process of producing mature sperm from Spermatogonial stem cells (SSCs) and this process requires a complex cooperation of different types of somatic and germ cells. Undifferentiated spermatogonia initiate the spermatogenesis and Sertoli cells as the only somatic cells inside of the seminiferous tubule play a key role in providing chemical and physical requirements for normal spermatogenesis, here, we investigated the dysfunction of these cells in non-obstructive azoospermia...
March 14, 2024: BMC Research Notes
https://read.qxmd.com/read/38486271/measurement-invariance-analysis-of-the-postpartum-specific-anxiety-scale-research-short-form-in-mothers-of-premature-and-term-infants
#14
JOURNAL ARTICLE
Semra Worrall, Paul Christiansen, Asma Khalil, Sergio A Silverio, Victoria Fallon
OBJECTIVE: Mothers of premature infants are more likely to develop anxiety during the first postpartum year than mothers of term infants. However, commonly used measures of anxiety were developed for general adult populations and may produce spurious, over-inflated scores when used in a postpartum context. Although perinatal-specific tools such as the Postpartum Specific Anxiety Scale [PSAS] offer a promising alternative form of measurement, it is not clear whether the measure performs similarly in mothers of premature infants as it does in mothers of term infants...
March 14, 2024: BMC Research Notes
https://read.qxmd.com/read/38486222/psychometric-properties-of-the-exercise-addiction-inventory-eai-questionnaire-among-physically-active-young-adults
#15
JOURNAL ARTICLE
Sahar Khoshro, Mahdieh Abbasalizad Farhangi, Leila Jahangiry
BACKGROUND: Exercise addiction (EA) is a pathological behavior pattern in which a person loses control over his exercise habits and exercises excessively and suffers negative consequences for his health and even his social life. One of the best tools to measure EA is EAI. The aim of this study was to examine the psychometric properties of the EAI among Iranian physically active young adults. METHODS: Participants were randomly selected from sports clubs in Tabriz, Iran...
March 14, 2024: BMC Research Notes
https://read.qxmd.com/read/38475890/correction-past-and-current-status-of-adolescents-living-with-hiv-in-south-africa-2005-2017
#16
Inbarani Naidoo, Sinovuyo Takatshana, Ronel Sewpaul, Sean Jooste, Zhou Siyanai, Goitseone Maseko, Sizulu Moyo, Khangelani Zuma, Musawenkosi Mabaso, Zungu Nompumelelo
No abstract text is available yet for this article.
March 12, 2024: BMC Research Notes
https://read.qxmd.com/read/38475887/correction-use-of-mobile-technology-to-identify-behavioral-mechanisms-linked-to-mental-health-outcomes-in-kenya-protocol-for-development-and-validation-of-a-predictive-model
#17
Willie Njoroge, Rachel Maina, Elena Frank, Lukoye Atwoli, Zhenke Wu, Anthony K Ngugi, Srijan Sen, JianLi Wang, Stephen Wong, Jessica A Baker, Eileen M Weinheimer-Haus, Linda Khakali, Andrew Aballa, James Orwa, Moses K Nyongesa, Jasmit Shah, Akbar K Waljee, Amina Abubakar, Zul Merali
No abstract text is available yet for this article.
March 12, 2024: BMC Research Notes
https://read.qxmd.com/read/38475880/correction-utility-of-a-penile-compression-device-for-the-quality-of-life-in-male-patients-with-urinary-incontinence-after-prostatectomy-the-more-study-a-randomized-prospective-study
#18
Daisuke Gotoh, Kazumasa Torimoto, Kenta Onishi, Yosuke Morizawa, Shunta Hori, Yasushi Nakai, Makito Miyake, Kiyohide Fujimoto
No abstract text is available yet for this article.
March 12, 2024: BMC Research Notes
https://read.qxmd.com/read/38475867/high-rates-of-international-code-violations-a-cross-sectional-study-in-a-region-of-canada-with-low-breastfeeding-rates
#19
JOURNAL ARTICLE
Susan Barry, Hannah Buckle, Leigh Anne Allwood Newhook, Barbara Roebothan, Brittany Howell, Heather Gates, Laurie K Twells
BACKGROUND: Exposure to marketing and promotion of commercial milk formula is associated with an increased likelihood of formula-feeding. In 1981, the International Code (IC) of Marketing of Breastmilk Substitutes was adopted by the 34th World Health Assembly to restrict the promotion, marketing and advertising of commercial milk formula and protect breastfeeding. RESEARCH AIM: The current study examines mothers' exposure to violations of the IC in Newfoundland and Labrador, a province of Canada with low breastfeeding rates...
March 12, 2024: BMC Research Notes
https://read.qxmd.com/read/38475810/impact-of-template-denaturation-prior-to-whole-genome-amplification-on-gene-detection-in-high-gc-content-species-burkholderia-mallei-and-b-pseudomallei
#20
JOURNAL ARTICLE
Chris R Taitt, Tomasz A Leski, Jaimee R Compton, Amy Chen, Kimberly L Berk, Robert W Dorsey, Shanmuga Sozhamannan, Dianne L Dutt, Gary J Vora
OBJECTIVE: In this study, we sought to determine the types and prevalence of antimicrobial resistance determinants (ARDs) in Burkholderia spp. strains using the Antimicrobial Resistance Determinant Microarray (ARDM). RESULTS: Whole genome amplicons from 22 B. mallei (BM) and 37 B. pseudomallei (BP) isolates were tested for > 500 ARDs using ARDM v.3.1. ARDM detected the following Burkholderia spp.-derived genes, aac(6), blaBP/MBL-3 , blaABPS , penA-BP, and qacE, in both BM and BP while blaBP/MBL-1 , macB, blaOXA-42/43  and penA-BC were observed in BP only...
March 12, 2024: BMC Research Notes
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