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BMC Research Notes

Omid Zarei, Leili Shokoohizadeh, Hadi Hossainpour, Mohammad Yousef Alikhani
OBJECTIVE: The objective of this study was to investigate the antibiotic susceptibility, virulence factors and clonal relationship among Pseudomonas aeruginosa isolated from environmental sources, hospitalized patients and the surfaces of cockroaches in the ICUs of four hospitals in Hamadan, west of Iran. A total of 237, 286 and 156 bacterial isolates were collected from clinical, environmental and cockroach sources respectively from May to September, 2017. The antimicrobial susceptibility was determined using disk diffusion method...
September 15, 2018: BMC Research Notes
Tchin Darré, Bayaki Saka, Abas Mouhari-Toure, Toukilnan Djiwa, Palokinam Pitché, Gado Napo-Koura
OBJECTIVE: The purpose of our study was to describe the histological diagnosed of the Basidiobolomycosis cases from 1990 to 2017 (28 years) in the only Pathology Anatomy Laboratory in Togo. RESULTS: A total of 12 cases of suspected Basidiobolomycosis have been identified. The sex ratio (M/F) was 2. The average age of the patients was 24.8 ± 1.6 years. Six patients (6/12) had a pathological history: HIV infection (n = 4 cases) and tuberculosis (n = 2 cases)...
September 14, 2018: BMC Research Notes
FengFei Huang, Manel Ben Aissa, Georges Lévesque, Madeleine Carreau
OBJECTIVE: The Uncoordinated 5A (UNC5A) protein is part of a family of receptors that play roles in axonal pathfinding and cell migration. We previously showed that the Fanconi anemia C protein (FANCC) interacts with UNC5A and delays UNC5A-mediated apoptosis. FANCC is a predominantly cytoplasmic protein that has multiple functions including DNA damage signaling, oxygen radical metabolism, signal transduction, transcriptional regulation and apoptosis. Given the direct interaction between FANCC and UNC5A and that FANCC interferes with UNC5A-mediated apoptosis, we explored the possibility that FANCC might play a role in axonal-like growth processes...
September 12, 2018: BMC Research Notes
Amir Ramezani, Mahin Alipouratigh, Lars Eng, Maria V Turkina, Johanna Lönn, Annette Theodorsson, Fariba Nayeri
OBJECTIVE: Cough and fever are the initial symptoms of lower respiratory infection. Severe cases might be fatal. Therefore, particularly in the non-equipped centers, the lack of diagnostic methods to identify the severe cases has resulted in overconsumption of antibiotics. On the basis of the knowledge about non-specific immune response at the site of injury, we developed a colorimetric dip-test that shows abrupt, sensitive and quite specific color change upon contact with sputum in the cases of lower respiratory infection...
September 12, 2018: BMC Research Notes
Rachid Achek, Helmut Hotzel, Zafer Cantekin, Ibrahim Nabi, Taha Mossadak Hamdi, Heinrich Neubauer, Hosny El-Adawy
OBJECTIVE: The antimicrobial resistance of staphylococci rose worldwide. In total, 96 Staphylococcus isolates from food and clinical samples were collected from two provinces in Algeria. The antimicrobial susceptibility testing was performed and resistance-associated genes were detected. RESULTS: Fifty-one strains were isolated from food samples and differentiated into 33 Staphylococcus aureus and 18 coagulase-negative staphylococci. Forty-five staphylococci were collected from hospital and community-acquired infection cases...
September 12, 2018: BMC Research Notes
Hiroaki Yanagawa, Rumi Katashima, Chiho Sato, Kenshi Takechi, Hiroshi Nokihara, Chikako Kane, Masayuki Chuma, Yuki Aoe
OBJECTIVE: Research ethics consultation is an advisory activity that differs from ethics committees, and its role is not yet widely known in Japan. Research ethics consultations were started in 2012 by members of the Clinical Trial Center of Tokushima University Hospital, a support section for clinical trials. We analyzed the research ethics consultation records from Tokushima University Hospital during the 5-year period of 2012-2016 to examine the Japanese context of research ethics consultation...
September 12, 2018: BMC Research Notes
Jeffrey R Janus, Stephen G Voss, Benjamin J Madden, Mary Cristine Charlesworth, Michael S Oldenburg, Dale Ekbom, Serban San-Marina
OBJECTIVES: Rabbit adipose mesenchymal stem cells were used for the purpose of studying acquisition of the chondrogenic phenotype over time at 1, 14 and 28 days after in vitro incubation with differentiation media, using nano-liquid chromatography electrospray ionization tandem mass spectrometry analysis. This was part of a preliminary study of the behavior of differentiated adipose stem cells for use in a rabbit model of laryngoplasty. DATA DESCRIPTION: The data comprise ...
September 12, 2018: BMC Research Notes
Ernst L Noordraven, André I Wierdsma, Peter Blanken, Anthony F T Bloemendaal, Cornelis L Mulder
OBJECTIVE: Offering a financial incentive ('Money for Medication') is effective in improving adherence to treatment with depot antipsychotic medications. We investigated the cost-effectiveness in terms of medical costs and judicial expenses of using financial incentives to improve adherence. The effects of financial incentives on depot medication adherence were evaluated in a randomised controlled trial. Patients in the intervention group received €30 a month over 12 months if antipsychotic depot medication was accepted...
September 10, 2018: BMC Research Notes
Thinley Dorji, Kinley Gyeltshen, Krit Pongpirul
OBJECTIVE: Paracetamol or acetaminophen is a weak analgesic commonly used worldwide and in Bhutan. It is available across all levels of Bhutan's health care system and for purchase without prescription. Little is known, however, about patterns of paracetamol use in Bhutan. This study aimed to assess what the Bhutanese population knows about the indications for use of paracetamol, safe use, and common patterns of usage (frequency, dosage). These questions were studied among Bhutanese living in Phuentsholing, a large commercial town at Bhutan-India border...
September 10, 2018: BMC Research Notes
Sitotaw Kerie, Ayele Tilahun, Alemnesh Mandesh
OBJECTIVE: The aim of this study was to assess levels of triage skill and associated factors among emergency nurses in Addis Ababa, Ethiopia, 2017. RESULTS: Above half of the participants (52.9%) had a moderate level of triage skill. A strong positive relationship was found between nurses' level of triage knowledge and skill (r = .68, p .01). Knowledge about triage, educational level and training experience had a significant relationship with triage skill with (B = 1...
September 10, 2018: BMC Research Notes
Pui-Ying Iroh Tam, Nelmary Hernandez-Alvarado, Mark R Schleiss, Amy J Yi, Fatimah Hassan-Hanga, Chuma Onuchukwu, Dominic Umoru, Stephen K Obaro
OBJECTIVES: Acute febrile illness is a common cause of hospital admission, and its associated infectious causes, of which a key bacterial causative agent is Streptococcus pneumoniae, contribute to substantial morbidity and mortality. We sought to evaluate the utility of real-time (rt)-PCR on dried blood spots (DBS) for diagnosis of S. pneumoniae in acute febrile illness among children presenting to hospitals in Nigeria. We previously described preliminary results in a sample of 537 patients...
September 10, 2018: BMC Research Notes
Ezra M Valido, Ida Safitri Laksanawati, Adi Utarini
OBJECTIVE: The study aims to illustrate the acceptability of the dengue vaccine before and after the dengue vaccination suspension in urban poor communities in Quezon City, Philippines. RESULTS: There were 12 interviews conducted in November 2017 and 5 focus group discussions in January 2018, a month after vaccine program suspension with 41 participants. All participants were selected through purposive criterion sampling. Thematic analysis showed acceptability of the dengue vaccine was associated with parental experience with vaccination and dengue, trust in public health institutions and communication received by parents...
September 10, 2018: BMC Research Notes
Reindolf Anokye, Enoch Acheampong, Amy Budu-Ainooson, Anthony Kwaku Edusei, Paul Okyere, Joslin Dogbe, Alberta Nadutey
OBJECTIVE: Immunization saves more than 3 million lives worldwide each year, and it saves millions from suffering illness and lifelong disability. The study sought to assess the socio-demographic factors that influence childhood immunization incompletion. A cross-sectional descriptive design was employed for the study conducted at the Child Welfare Clinic in the Regional Hospital, Koforidua. A total of 280 caregivers/mothers who have children aged between 0 and 59 months were included in this study...
September 10, 2018: BMC Research Notes
Novi Pusparini, Diana E Waturangi, Tepy Usia, Eva Nikastri
OBJECTIVE: The prevalence of Escherichia coli including from ice cubes in Indonesia is quite high. Unfortunately, little is known about the genetic diversity of E. coli from ice cube production site. Genotypic variation in E. coli populations is a major barrier to control public health risk associated with foodborne pathogen. The aims of this study were to analyze the genotypic diversity of E. coli strains isolated from various samples in order to determine the genetic relationship between those strains...
September 10, 2018: BMC Research Notes
Margarete E Vollrath, Svenn Torgersen, Leila Torgersen
OBJECTIVE: Our aim is to examine the associations of the Big Five personality factors with eating behaviors in children using a cross-sectional study in 1543 randomly Norwegian 7-12 year olds. RESULTS: Mothers rated the hierarchical personality inventory for children, and the child eating behaviour questionnaire to describe her child. Personality and eating behaviors were substantially associated in bivariate correlations and multivariate analyses of variance. The strongest predictors of eating behaviors were neuroticism, followed by agreeableness and conscientiousness...
September 10, 2018: BMC Research Notes
Mitsuhiro Sado, Sunre Park, Akira Ninomiya, Yasuko Sato, Daisuke Fujisawa, Joichiro Shirahase, Masaru Mimura
OBJECTIVE: Mindfulness-based cognitive therapy (MBCT) could be a treatment option for anxiety disorders. Although its effectiveness under conditions of low pharmacotherapy rates has been demonstrated, its effectiveness under condition of high pharmacotherapy rate is still unknown. The aim of the study was to evaluate effectiveness of MBCT under the context of high pharmacotherapy rates. RESULTS: A single arm with pre-post comparison design was adopted. Those who had any diagnosis of anxiety disorders, between the ages of 20 and 74, were included...
September 6, 2018: BMC Research Notes
Mekdes Tigistu, Telake Azale, Habtamu Kebebe, Temesgen Yihunie
OBJECTIVE: About three-fourth of adults with new-onset epilepsy become seizure-free with current anti-epileptic drugs, but around one-fourth of the patients continue to experience seizure which increases the risk of accident, disability, death and treatment side effects. Therefore, this study aimed to address the gap in determining the magnitude of the number of seizure attacks and identify the factors that provoke a repeated seizure in a patient with epilepsy. RESULTS: A total of 166(40...
September 6, 2018: BMC Research Notes
Srinivasarao Thota
OBJECTIVES: In this paper, we discuss a Maple package, deaSolve, of the symbolic algorithm for solving an initial value problem for the system of linear differential-algebraic equations with constant coefficients. RESULTS: Using the proposed Maple package, one can compute the desired Green's function of a given IVP. Sample computations are presented to illustrate the Maple package.
September 6, 2018: BMC Research Notes
Dankmar Böhning, Walailuck Böhning, Nishan Guha, David A Cowan, Christiaan Bartlett, Peter H Sönksen, Richard I G Holt
OBJECTIVE: The GH-2000 biomarker test has been introduced by the World Anti-Doping Agency as a method of detecting growth hormone misuse in professional sport. The test involves the measurement insulin-like growth factor-I and the amino-terminal pro-peptide of type III collagen (P-III-NP) which increase in a dose-dependent manner in response to GH. These measurements are combined in sex specific formulae that include an age adjustment. The original age adjustment overcorrects the effect of age in male athletes and could potentially place older men at a disadvantage...
September 5, 2018: BMC Research Notes
Elena M Marron, Raquel Viejo-Sobera, María Quintana, Diego Redolar-Ripoll, Daniel Rodríguez, Maite Garolera
OBJECTIVE: Alzheimer's disease is a major health problem in our society. To date, pharmacological treatments have obtained poor results and there is a growing interest in finding non-pharmacological interventions for this disease. Transcranial magnetic stimulation (TMS) is a non-invasive technique that is able to induce changes in brain activity and long-term modifications in impaired neural networks, becoming a promising clinical intervention. Our goal is to study the benefit of individualized TMS targeting based on the patient's functional connectivity (personalized targeting), and short duration TMS protocol, instead of current non-individualized and longer session approaches...
September 5, 2018: BMC Research Notes
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