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BMC Research Notes

Mohamad Elaibaid, Lama H Nazer, Lama Shaikha, Nada Al-Qadheeb, Ruth Kleinpell, Keith M Olsen, Feras Hawari
OBJECTIVES: Evaluation of published research in a region provides insight into relevant aspects of clinical care and research priorities. This study aimed to provide a comprehensive assessment of the type of critical care research published in the World Health Organization Eastern Mediterranean region (EMR) over a 10-year period. RESULTS: During the study period (2007-2016), the search strategy revealed 4303 publications, of which 1537 were included in the analysis; studies were excluded for the following reasons: not critical care, conducted in non-EMR countries, editorials, case reports, in-vitro or animal studies, as well as those conducted in multiple countries and those that evaluated foreign military personal...
January 18, 2019: BMC Research Notes
Jendai Richards, Elizabeth R Unger, Mangalathu S Rajeevan
OBJECTIVE: Studies of mRNA and miRNA expression profiling increasingly use stabilized whole blood. Commercial RNA extraction kits do not provide information about the simultaneous recovery of both mRNA and miRNA. This study evaluated yield, quality, integrity and representation of mRNA and miRNA from whole blood stabilized in Tempus tubes using three RNA extraction kits; two filter-based (Tempus and Norgen) and one bead-based (MagMax; manual vs. semi-automated, and with and without DNase treatment)...
January 18, 2019: BMC Research Notes
Samwel Saringe, Debora C Kajeguka, Dickson D Kagirwa, Maseke R Mgabo, Basiliana Emidi
OBJECTIVE: Dengue and chikungunya virus diseases are becoming an increasingly important global health threats and are continuously expanding their geographical range. The study aims to investigate knowledge and diagnostic practice of dengue and chikungunya fever among healthcare workers in Moshi Municipality. RESULTS: Most of healthcare workers heard of chikungunya and dengue 146 (71.2%) and 203 (99%) respectively. Ninety-five (46.3%) and 152 (74.1%) had good knowledge regard chikungunya and dengue respectively...
January 18, 2019: BMC Research Notes
Clovis Nkoke, Denis Teuwafeu, Alice Mapina, Cyrille Nkouonlack
OBJECTIVE: Our goal was to study the clinical characteristics, risk factors and outcome of patients admitted for venous thromboembolism (VTE) in the medical unit of the Buea Regional Hospital, Cameroon between 1st July 2016 and 30th November 2017. RESULTS: Twenty-two patients were admitted for VTE. There were 12 (54.4%) men. The mean age was 54.9 ± 13.9 years (range: 31-77 years). The main risk factors were immobilization (40.9%), HIV infection (22.7%), tuberculosis (18...
January 18, 2019: BMC Research Notes
Rabina Dumaru, Ratna Baral, Lok Bahadur Shrestha
OBJECTIVES: Gram-negative bacilli are the common causative agents for community-acquired, nosocomial and opportunistic infections. The recent upsurge of biofilm, as well as beta-lactamases producing strains, have synergistically led to the extensive dissemination of multi-drug resistant gram-negative bacilli. This study was carried out with an intention to detect the biofilm formation by gram-negative bacilli and determine their antibiogram along with the detection of extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs) production...
January 18, 2019: BMC Research Notes
Zhongyi Chen, Simon Deblois, Kevin Toporowicz, Irina Boldeanu, Marie-Odile Francoeur, Manel Sadouni, Luigi Lepanto, Carl Chartrand-Lefebvre
OBJECTIVE: To assess computed tomography pulmonary angiography (CTPA) positive yield rate for pulmonary embolism (PE) in a Canadian academic tertiary center. RESULTS: This one-center retrospective cross-sectional study includes from 5565 (model 1) to 5296 (model 2) patients that were evaluated for suspected PE in 2015, among which 1331 (23.9% (model 1) to 25.1% (model 2)) underwent CTPA. Mean age of CTPA patients was 60.2 ± 16.6 years, of which 575 were males (43...
January 18, 2019: BMC Research Notes
Nuwanthika Kumarasinghe, Walter N Moss
OBJECTIVE: The pre-mRNA of the Epstein-Barr virus LMP2 (latent membrane protein 2) has a region of unusual RNA structure that partially spans two consecutive exons and the entire intervening intron; suggesting RNA folding might affect splicing-particularly via interactions with human regulatory proteins. To better understand the roles of protein associations with this structured intronic region, we undertook a combined bioinformatics (motif searching) and experimental analysis (biotin pulldowns and RNA immunoprecipitations) of protein binding...
January 18, 2019: BMC Research Notes
Atif Ali Hashmi, Erum Yousuf Khan, Muhammad Irfan, Rabia Ali, Huda Asif, Maheen Naeem, Laila Nisar, Naveen Faridi, Amir Khan, Muhammad Muzzammil Edhi
OBJECTIVES: T/E fusion results in constitutive expression of ERG oncoprotein resulting in enhanced proliferation and invasive potential of prostatic cancer cells. In the present study we aimed to evaluate the ERG overexpression in 78 cases prostate acinar adenocarcinoma and its association with other prognostic parameters. RESULTS: ERG protein expression was noted in 39.7% (31 cases), out of which 3 cases (3.8%) showed low ERG expression, 10 cases (12.8%) showed intermediate expression and 18 cases (23...
January 18, 2019: BMC Research Notes
Haftom Niguse, Goitom Belay, Girmatsion Fisseha, Tesfaye Desale, Goitom Gebremedhn
OBJECTIVE: A good self-care practice is important for patients with diabetes to achieve the desired treatment targets and to contribute meaningfully in the management of their disease. The study aimed to assess the level of knowledge, attitude and practice of diabetes self-care and to identify the factors associated with diabetes self-care. RESULTS: A total of 338 patients with diabetes having mean age of 45.8 years were included in the study. Among those 70.4%, 70...
January 18, 2019: BMC Research Notes
Meysam Behzadifar, Masoud Behzadifar, Ahad Bakhtiari, Samad Azari, Mandana Saki, Farnaz Golbabayi, Nicola Luigi Bragazzi
OBJECTIVE: Cesarean section (CS) is one of the most common surgical procedures in the world. In developed and developing countries, CS has grown significantly over the past decades. The Iranian Ministry of Health and Medical Education has developed a health transformation plan (HTP) in order to reduce CS rate and promote vaginal delivery. This study was conducted with the aim of reviewing the results of published studies on the impact of the HTP on CS in Iran. RESULTS: We searched Embase, PubMed/MEDLINE, ISI/Web of Sciences, Scopus, as well as Iranian databases (MagIran, SID and Barakatkns), from May 2014 to October 2018...
January 18, 2019: BMC Research Notes
Mebratu Mitiku Reta, Gizachew Assefa Tessema, Getachew Shiferaw
OBJECTIVE: Dual contraceptive is the use of male condom besides any modern contraceptive. It reduces parent to child transmission of HIV and other sexually transmitted infections between partners. The aim of this study was to investigate the prevalence and associated factors of dual contraceptive use among HIV positive women at University of Gondar Hospital, North West Ethiopia. RESULT: The prevalence of dual contraceptive use was found to be 13.2% (95% CI 10.5, 16...
January 18, 2019: BMC Research Notes
T Elizabeth Workman, Yijun Shao, Guy Divita, Qing Zeng-Treitler
OBJECTIVE: Misspellings in clinical free text present challenges to natural language processing. With an objective to identify misspellings and their corrections, we developed a prototype spelling analysis method that implements Word2Vec, Levenshtein edit distance constraints, a lexical resource, and corpus term frequencies. We used the prototype method to process two different corpora, surgical pathology reports, and emergency department progress and visit notes, extracted from Veterans Health Administration resources...
January 18, 2019: BMC Research Notes
Tahir Jameel, Zohair Jamil Gazzaz, Mukhtiar Baig, Jawad Mansoor Tashkandi, Nasser Saleh Alharenth, Nadeem Shafique Butt, Ansar Shafique, Rahila Iftikhar
OBJECTIVE: The purpose of the present study was to explore why our medical students are avoiding the study of professional textbooks. We conducted this study from 10th March to 15th May 2017 at the King Abdulaziz University (KAU), Jeddah, to investigate their preferences towards learning resources, their study habits and correlation of academic achievements as a result of these trends. A questionnaire was provided as a web link. The participants of the study included medical students and data was analyzed on SPSS-Version 21...
January 17, 2019: BMC Research Notes
Getiye Dejenu Kibret, Cheru Tesema Leshargie, Fasil Wagnew, Animut Alebel
OBJECTIVE: The main purpose of this research was to determine the magnitude of willingness to join to community based health insurance (CBHI) and to identify factors associated with it. RESULTS: A total of 604 study participants responded for the interviews, making the response rate 98.2%. All in all, 492 (81.5%) of the study participant households were willing to join the CBHI scheme. Households which had experience of borrowing for medical expenses within the last 12 months prior to the study were 2...
January 17, 2019: BMC Research Notes
Akua Obeng Forson, Wilson Bright Tsidi, David Nana-Adjei, Marjorie Ntiwaa Quarchie, Noah Obeng-Nkrumah
Following publication of the original article [1], the authors reported that one of the authors' names was spelled incorrectly. In this Correction the incorrect and correct author name are shown. The original publication of this article has been corrected.
January 16, 2019: BMC Research Notes
Suhair Kamalaldeen Shomeina, Osman Taha Elzaki, Sakina Yagi, Salaheldin Dafaalla Mohieldin, Tarig Osman Khider
THE OBJECTIVES: The work was carried out for extraction of natural anthrasesamones from roots of Sesamum Indicum using different organic solvents and utilization of extracts as catalyst in pulping with sodium hydroxide for a by-product of sugar industry (Sudanese bagasse). RESULTS: Sesamum Indicum roots when extracted with ethanol, it gave the highest extracts yield % (0.964), followed by ethyl acetate, chloroform, dichloromethane and petroleum ether extracts. The chemical pulping of Bagasse was done by using of sodium hydroxide, sodium hydroxide with anthraquinone, and sodium hydroxide with extract instead of anthraquinone keeping constant conditions at temperature 160 °C and applied sodium oxide 10...
January 15, 2019: BMC Research Notes
Akissi Régine Attia-Konan, Agbaya Stéphane Serge Oga, Amadou Touré, Kouakou Luc Kouadio
OBJECTIVE: The purpose and objective of our research is to identify the determinants of the out of pocket (OOP) health expenditures in the population of Ivory Coast and the ratios across three different area; Abidjan, the rural and urban area. We used data from the 2015 standard households living survey conducted by the National Institute of Statistic. RESULTS: About 6315 (13.3%) of the participants had experienced OOP health expenditure. There was significant differences in the self-reported OOP between these three areas (p < 0...
January 15, 2019: BMC Research Notes
Ramin Khodayary, Iraj Nikokar, Mohammad Reza Mobayen, Farhad Afrasiabi, Afshin Araghian, Ali Elmi, Meisam Moradzadeh
OBJECTIVE: The present study aimed to determine the prevalence of virulence factors and antimicrobial resistance profile of Pseudomonas aeruginosa strains isolated from Iranian burn patients. RESULTS: This cross-sectional study performed on 100 P. aeruginosa isolates which were recovered from burn wound specimens in 2014-2015. All presumptive isolates were identified by standard microbiologic tests. Antimicrobial susceptibility test was carried out by disk diffusion method...
January 15, 2019: BMC Research Notes
Yingjie Tian, Hui Yu, Zhanli Wang
OBJECTIVE: This study investigated the distribution of acquired antibiotic resistance genes in Enterococcus species isolated from clinical patients in Baotou, China. RESULT: A total of 73 enterococca lisolates from clinical samples were collected from December 2016 to September 2017. Of the 73 enterococcal isolates, 36 (49.3%), 35 (47.9%), 1 (1.4%), and 1 (1.4%) were identified as E. faecium, E. faecalis, E. gallinarum, and E. raffinosus, respectively. The resistance rates of the enterococci to nitrofurantoin, tetracycline, gentamicin (high-level), ampicillin, ciprofloxacin and erythromycin were 24...
January 15, 2019: BMC Research Notes
Lydia Mali Langata, John M Maingi, Harry Asena Musonye, John Kiiru, Anthony Kebira Nyamache
OBJECTIVE: Increase in antimicrobial resistance is a threat to health sector globally. Surveillance on the spread and emergence of antimicrobial resistance is therefore invertible. This study investigated prevalence of Salmonella and Escherichia coli, molecularly characterized their antimicrobial resistance patterns and spread among resistant isolates from chicken droppings. RESULTS: A total of 150 chicken households were selected randomly within Nairobi and fresh chicken droppings collected...
January 14, 2019: BMC Research Notes
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