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BMC Research Notes

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https://www.readbyqxmd.com/read/29329603/green-tobacco-sickness-among-brazilian-farm-workers-and-genetic-polymorphisms
#1
Marcelo Soares da Mota E Silva, Maria da Glória da Costa Carvalho, Josino Costa Moreira, Emiliano de Oliveira Barreto, Karol Fireman de Farias, Cristiane Araújo Nascimento, Francisca Maria Nunes da Silva, Tiago Gomes de Andrade, Ronir Raggio Luiz, Rodrigo Soares de Moura Neto, Fernanda Lattario Ribeiro
OBJECTIVE: Green Tobacco Sickness (GTS) is an occupational illness caused by dermal absorption of nicotine from tobacco leaves. It affects thousands of farm workers worldwide. Brazil is the second tobacco producer in the world; despite this, there are few studies on GTS among Brazilian harvesters. This study aimed to determine the prevalence of GTS among a population of tobacco workers from a producing area in northeastern Brazil and investigate whether the occurrence of the disease was influenced by factors such age, gender and smoking status...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29329601/nicotiana-glauca-whole-genome-investigation-for-ct-dna-study
#2
Galina Khafizova, Pavel Dobrynin, Dmitrii Polev, Tatiana Matveeva
OBJECTIVE: Nicotiana glauca (tree tobacco) is a naturally transgenic plant, containing sequences acquired from Agrobacterium rhizogenes by horizontal gene transfer. Besides, N. glauca contains a wide profile of alkaloids of medical interest. DATA DESCRIPTION: We report a high-depth sequencing and de novo assembly of N. glauca full genome and analysis of genome elements with bacterial origin. The draft genome assembly is 3.2 Gb, with N50 size of 31.1 kbp. Comparative analysis confirmed the presence of single, previously described gT insertion...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29329600/optimal-waist-circumference-cut-off-points-for-predicting-metabolic-syndrome-among-low-income-black-south-african-adults
#3
Eyitayo Omolara Owolabi, Daniel Ter Goon, Oladele Vincent Adeniyi, Anthony Idowu Ajayi
OBJECTIVE: Waist circumference has been identified as one of the strongest predictive tool for metabolic syndrome. This study determines the optimal cut-off point of waist circumference for metabolic syndrome among low-income earning South African black population, in Eastern Cape, South Africa. The optimal waist circumference cut-off point was determined through receiver operating characteristics analysis using the maximum Youden index. RESULTS: Among men, waist circumference at a cut-off value of 95...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29329598/treatment-outcome-of-anti-angiogenesis-through-vegf-pathway-in-the-management-of-gastric-cancer-a-systematic-review-of-phase-ii-and-iii-clinical-trials
#4
Brian Mawalla, Xianglin Yuan, Xiaoxiao Luo, Phillip L Chalya
OBJECTIVES: Advanced gastric cancer poses a therapeutic challenge worldwide. In randomised clinical trials, anti-VEGF has been reported as an essential agent for the treatment of advanced gastric cancer. This review aims at assessing the treatment outcome of anti-angiogenesis therapy through the VEGF pathway in the management of patients with advanced gastric cancer. RESULTS: During this review, 38 clinical trials were identified. Of these, 30 clinical trials were excluded, leaving eight trials of phase II and III...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29329597/does-cognitive-behavioral-therapy-alter-mental-defeat-and-cognitive-flexibility-in-patients-with-panic-disorder
#5
Shinobu Nagata, Yoichi Seki, Takayuki Shibuya, Mizue Yokoo, Tomokazu Murata, Yoichi Hiramatsu, Fuminori Yamada, Hanae Ibuki, Noriko Minamitani, Naoki Yoshinaga, Muga Kusunoki, Yasushi Inada, Nobuko Kawasoe, Soichiro Adachi, Keiko Oshiro, Daisuke Matsuzawa, Yoshiyuki Hirano, Kensuke Yoshimura, Michiko Nakazato, Masaomi Iyo, Akiko Nakagawa, Eiji Shimizu
OBJECTIVE: Mental defeat and cognitive flexibility have been studied as explanatory factors for depression and posttraumatic stress disorder. This study examined mental defeat and cognitive flexibility scores in patients with panic disorder (PD) before and after cognitive behavioral therapy (CBT), and compared them to those of a gender- and age-matched healthy control group. RESULTS: Patients with PD (n = 15) received 16 weekly individual CBT sessions, and the control group (n = 35) received no treatment...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29329594/modelling-the-structure-of-a-cerna-theoretical-bipartite-microrna-mrna-interaction-network-regulating-intestinal-epithelial-cellular-pathways-using-r-programming
#6
J M Robinson, W A Henderson
OBJECTIVE: We report a method using functional-molecular databases and network modelling to identify hypothetical mRNA-miRNA interaction networks regulating intestinal epithelial barrier function. The model forms a data-analysis component of our cell culture experiments, which produce RNA expression data from Nanostring Technologies nCounter® system. The epithelial tight-junction (TJ) and actin cytoskeleton interact as molecular components of the intestinal epithelial barrier. Upstream regulation of TJ-cytoskeleton interaction is effected by the Rac/Rock/Rho signaling pathway and other associated pathways which may be activated or suppressed by extracellular signaling from growth factors, hormones, and immune receptors...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29325587/human-echinostomiasis-a-case-report
#7
Ranjit Sah, Shusila Khadka, Rabin Hamal, Sagar Poudyal
BACKGROUND: Echinostomiasis is a food-borne infection caused by an intestinal trematodes belonging to the family Echinostomatidae. They infect the gastrointestinal tract of humans. Patients are usually asymptomatic. However, with heavy infections, the worms can produce catarrhal inflammation with mild ulceration and the patient may experience abdominal pain, anorexia, nausea, vomiting, diarrhea and weight loss. Infection are associated with common sociocultural practices of eating raw or insufficiently cooked mollusks and fish...
January 11, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29325576/reanalysis-of-chinese-treponema-pallidum-samples-all-chinese-samples-cluster-with-ss14-like-group-of-syphilis-causing-treponemes
#8
Michal Strouhal, Jan Oppelt, Lenka Mikalová, Natasha Arora, Kay Nieselt, Fernando González-Candelas, David Šmajs
OBJECTIVE: Treponema pallidum subsp. pallidum (TPA) is the causative agent of syphilis. Genetic analyses of TPA reference strains and human clinical isolates have revealed two genetically distinct groups of syphilis-causing treponemes, called Nichols-like and SS14-like groups. So far, no genetic intermediates, i.e. strains containing a mixed pattern of Nichols-like and SS14-like genomic sequences, have been identified. Recently, Sun et al. (Oncotarget 2016. https://doi.org/10.18632/oncotarget...
January 11, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29321059/intrarater-reliability-of-the-humac-norm-isokinetic-dynamometer-for-strength-measurements-of-the-knee-and-shoulder-muscles
#9
Bas Habets, J Bart Staal, Marsha Tijssen, Robert van Cingel
OBJECTIVE: To determine the intrarater reliability of the Humac NORM isokinetic dynamometer for concentric and eccentric strength tests of knee and shoulder muscles. RESULTS: 54 participants (50% female, average age 20.9 ± 3.1 years) performed concentric and eccentric strength measures of the knee extensors and flexors, and the shoulder internal and external rotators on two different Humac NORM isokinetic dynamometers, which were situated at two different centers...
January 10, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29321038/cross-sectional-study-to-assess-the-accuracy-of-electronic-health-record-data-to-identify-patients-in-need-of-lung-cancer-screening
#10
Allison M Cole, Bethann Pflugeisen, Malaika R Schwartz, Sophie Cain Miller
OBJECTIVE: Lung cancer is the leading cause of cancer death in the United States [Siegel et al. in CA Cancer J Clin 66:7-30, 1]. However, evidence from clinical trials indicates that annual low-dose computed tomography screening reduces lung cancer mortality [Humphrey et al. in Ann Intern Med 159:411-420, 2]. The objective of this study is to report results of a study designed to assess the sensitivity, specificity, and positive and negative predictive value of an electronic health record (EHR) query in comparison to patient self-report, to identify patients who may benefit from lung cancer screening...
January 10, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29316966/hiss-and-snort-call-types-of-wild-living-giraffes-giraffa-camelopardalis-acoustic-structure-and-context
#11
Elena V Volodina, Ilya A Volodin, Elena V Chelysheva, Roland Frey
OBJECTIVES: Vocalization as part of vigilance behaviour is widespread across animal taxa, including ruminants. Calls of wild-living giraffes have never been recorded and spectrographically investigated. This study reports the acoustic structure of vigilance-related hiss and snort calls of wild-living giraffes Giraffa camelopardalis. RESULTS: The hiss and snort calls were emitted during five recording sessions produced by nine individual giraffes (8 adults and 1 subadult) in their natural environment in Namibia (3 individuals) and Kenya (6 individuals)...
January 9, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29316964/genome-wide-diversity-and-runs-of-homozygosity-in-the-braque-fran%C3%A3-ais-type-pyr%C3%A3-n%C3%A3-es-dog-breed
#12
Salvatore Mastrangelo, Filippo Biscarini, Barbara Auzino, Marco Ragatzu, Andrea Spaterna, Roberta Ciampolini
OBJECTIVE: Braque Français, type Pyrénées is a French hunting-dog breed whose origin is traced back to old pointing gun-dogs used to assist hunters in finding and retrieving game. This breed is popular in France, but seldom seen elsewhere. Despite the ancient background, the literature on its genetic characterization is surprisingly scarce. A recent study looked into the demography and inbreeding using pedigree records, but there is yet no report on the use of molecular markers in this breed...
January 9, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29310721/the-utility-of-dna-extracted-from-saliva-for-genome-wide-molecular-research-platforms
#13
Fiona J Bruinsma, Jihoon E Joo, Ee Ming Wong, Graham G Giles, Melissa C Southey
OBJECTIVE: The study aimed to investigate the suitability of DNA extracted from saliva for high throughput molecular genotyping and DNA methylation platforms by comparing its performance with that of DNA extracted from blood. The genome-wide methylation profile, using the Infinium HumanMethylation450 Beadchip array® (Illumina, San Diego, CA), was measured for 20 DNA samples. Common genetic variation was measured, using the Infinium HumanCore Beadchip® (Illumina, San Diego, CA) for 4 samples (matching samples from 2 people)...
January 8, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29310715/fast-and-accurate-identification-of-cryptic-and-sympatric-mayfly-species-of-the-baetis-rhodani-group
#14
Roberta Bisconti, Roberta Tenchini, Carlo Belfiore, Giuseppe Nascetti, Daniele Canestrelli
OBJECTIVE: Species of the Baetis rhodani group are among the most widespread mayflies of the Palearctic region. However, frequent occurrence of morphologically cryptic species complicates the identification of sympatric species. Here, we proposed and tested a method for the fast, accurate, and cost-effective assignment of a large number of individuals to their putative species, based on high resolution melting profiles of a standard mitochondrial gene fragment. We tested this method using a system of three recently identified cryptic species inhabiting the Tyrrhenian Islands (western Mediterranean basin)...
January 8, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29310708/the-pharms-patient-held-active-record-of-medication-status-feasibility-study-a-research-proposal
#15
Elaine Walsh, Laura J Sahm, Patricia M Kearney, Henry Smithson, David M Kerins, Chrys Ngwa, Ciara Fitzgerald, Stephen Mc Carthy, Eimear Connolly, Kieran Dalton, Derina Byrne, Megan Carey, Colin Bradley
Medication errors are a major source of preventable morbidity, mortality and cost and many occur at the times of hospital admission and discharge. Novel interventions (such as new methods of recording medication information and conducting medication reconciliation) are required to facilitate accurate transfer of medication information. With existing evidence supporting the use of information technology and the patient representing the one constant in the care process, an electronic patient held medication record may provide a solution...
January 8, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29310707/development-of-ahmite1-markers-through-genome-wide-analysis-in-peanut-arachis-hypogaea-l
#16
M Gayathri, Kenta Shirasawa, R K Varshney, M K Pandey, R S Bhat
OBJECTIVE: In peanut, the DNA polymorphism is very low despite enormous phenotypic variations. This limits the use of genomics-assisted breeding to enhance peanut productivity. This study aimed to develop and validate new AhMITE1 and cleaved amplified polymorphic sequences (CAPS) markers. RESULTS: In total, 2957 new AhMITE1 markers were developed in addition to identifying 465 already reported markers from the whole genome re-sequencing data (WGRS) of 33 diverse genotypes of peanut...
January 8, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29310699/planning-a-sports-training-program-using-adaptive-particle-swarm-optimization-with-emphasis-on-physiological-constraints
#17
Nattapon Kumyaito, Preecha Yupapin, Kreangsak Tamee
OBJECTIVE: An effective training plan is an important factor in sports training to enhance athletic performance. A poorly considered training plan may result in injury to the athlete, and overtraining. Good training plans normally require expert input, which may have a cost too great for many athletes, particularly amateur athletes. The objectives of this research were to create a practical cycling training plan that substantially improves athletic performance while satisfying essential physiological constraints...
January 8, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29310696/methods-for-detecting-gemmata-spp-bacteremia-in-the-microbiology-laboratory
#18
Jacques-Robert Christen, Edwin Edmond, Michel Drancourt
OBJECTIVE: Gemmata bacteria are fastidious, Gram-negative and aerobic. The only representatives are Gemmata obscuriglobus and Gemmata massiliana. These Planctomycetes appear to be a part of human digestive tract microbiome, and G. massiliana has been isolated from water. Further specific detection in the blood of two patients with febrile neutropenia suggests that Gemmata bacteremia may remain under-documented. The objective of this study was to develop an effective protocol to document Gemmata spp...
January 8, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29304830/emergence-of-g12-and-g9-rotavirus-genotypes-in-the-central-african-republic-january-2014-to-february-2016
#19
Ulrich Aymard Ekomi Moure, Virginie Banga-Mingo, Jean Chrysostom Gody, Jason M Mwenda, Jean Fandema, Diane Waku-Kouomou, Casimir Manengu, Thomas D'Aquin Koyazegbe, Mathew D Esona, Michael D Bowen, Ionela Gouandijka-Vasilache
OBJECTIVES: Rotavirus gastroenteritis is a major cause of death among children under 5 years globally. A rotavirus gastroenteritis surveillance program started in October 2011 in the Central African Republic (CAR) with the Surveillance Epidémiologique en Afrique Centrale (SURVAC) project. We present here genotyping results showing the emergence of G9 and G12 genotypes in Central African Republic. RESULTS: Among 222 children hospitalized with acute gastroenteritis who had a stool sample collected at the sentinel site, Complexe Pédiatrique de Bangui (CPB), Bangui, Central African Republic, 100 (45%) were positive for rotavirus between January 2014 and February 2016...
January 5, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29298731/spontaneous-rhythms-in-a-harbor-seal-pup-calls
#20
Andrea Ravignani
OBJECTIVES: Timing and rhythm (i.e. temporal structure) are crucial, though historically neglected, dimensions of animal communication. When investigating these in non-human animals, it is often difficult to balance experimental control and ecological validity. Here I present the first step of an attempt to balance the two, focusing on the timing of vocal rhythms in a harbor seal pup (Phoca vitulina). Collection of this data had a clear aim: To find spontaneous vocal rhythms in this individual in order to design individually-adapted and ecologically-relevant stimuli for a later playback experiment...
January 3, 2018: BMC Research Notes
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