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Triglycerides as indicators of erythrocyte hemoglobin oxygen-binding properties1.
OBJECTIVES: To assess the relationships of clinical and laboratory parameters, with erythrocyte oxygen concentration.
METHODS: The study group consisted of 47 healthy adults out of which 16 showed slightly higher blood pressure and were classified as individuals with prehypertension. For each individual, data were obtained on: systolic and diastolic blood pressure (SBP, DBP), blood morphology, lipids profile, fibrinogen, hs-CRP. The erythrocyte oxygen concentration was assessed with the Raman spectroscopy technique. Arithmetic means for all laboratory parameters were estimated by oxygen concentration tertiles and tested for statistical significance of linear trends across tertiles.
RESULTS: The multivariate regression analysis showed statistically significant negative relationship of triglycerides level with oxygen concentration.
CONCLUSIONS: A hypothesis has been formulated that triglycerides level is an indicator of the erythrocyte ability to transport oxygen to the tissues.
METHODS: The study group consisted of 47 healthy adults out of which 16 showed slightly higher blood pressure and were classified as individuals with prehypertension. For each individual, data were obtained on: systolic and diastolic blood pressure (SBP, DBP), blood morphology, lipids profile, fibrinogen, hs-CRP. The erythrocyte oxygen concentration was assessed with the Raman spectroscopy technique. Arithmetic means for all laboratory parameters were estimated by oxygen concentration tertiles and tested for statistical significance of linear trends across tertiles.
RESULTS: The multivariate regression analysis showed statistically significant negative relationship of triglycerides level with oxygen concentration.
CONCLUSIONS: A hypothesis has been formulated that triglycerides level is an indicator of the erythrocyte ability to transport oxygen to the tissues.
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