[Daily Life Style and Psoriasis].

Skin is an important organ that is located on the outermost layer of the human body, and serves as a defense barrier against external stimulation. Daily life style, including diet, exercise, and sleep, is a fundamental behavior of humans, and it has recently been reported that daily life style has a strong relationship with the inflammatory condition of skin diseases. This relationship has been examined by various approaches, including epidemiological investigations. Psoriasis is one inflammatory skin disease and is especially closely related with daily life style, such as diet, sleep, smoking and alcohol consumption. The interleukin (IL)-23/IL-17 axis plays an important role in the pathogenesis of psoriasis, and daily life style is considered to affect this cascade, leading to exacerbation of the inflammatory condition. In this review article, we report how daily life style affects psoriasis.