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Journal of UOEH

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2018: Journal of UOEH
Aki Satoh, Yuki Nagamatsu, Tomohiro Matsumura
Enabling students to acquire practical skills that can be utilized after graduation has become an agenda for basic nursing education since the start of Japan's "super-aging society" and the sophistication of modern medical treatment. Nursing schools are attempting to introduce the Objective Structured Clinical Examination (OSCE) in an attempt to integrate this important agenda. OSCE has been implemented at our school of nursing since 2014 in the first semester for third year students as a part of the integrated course for clinical training...
2018: Journal of UOEH
Yuzuru Inoue, Shiro Kohi, Masato Gobara, Fumi Joden, Kei Yabuki, Takayuki Tanoue, Nagahiro Sato, Takefumi Katsuki, Takahisa Nagata, Kazunori Shibao, Masanori Hisaoka, Keiji Hirata
The case presented herein was a 70-year-old woman who had no compliant, but had a mass in the lower part of the right lobe of the thyroid detected by ultrasound (US). The US image of the tumor, measuring 13 mm in diameter, showed a low and heterogeneous internal echo level with calcification and an irregular margin. The tumor appeared to extend to the adjacent sternothyroid muscle, and cervical lymph node swelling was detected in a computer tomography (CT) image, but no metastatic lesion was found by positron emission tomography (PET)-CT...
2018: Journal of UOEH
Tomomi Ikegami, Shunsuke Araki, Mami Kuwamura, Aoi Taku, Reiko Saito, Motohide Goto, Kazuyasu Kubo, Rinko Kawagoe, Yukiyo Yamamoto, Yasusada Kawada, Koichi Kusuhara
Growth hormone (GH) therapy for short children born small for gestational age (SGA) has been approved in Japan. It is important to evaluate GH secretion ability before the initiation of GH therapy because there are some differences in dose and medical expenses between short children born SGA and GH deficiency (GHD). This study was designed to elucidate the incidence of GHD and to find a useful marker for detecting it in short SGA children. We retrospectively reviewed medical records to analyze the clinical features of short children born SGA and with GHD who had started GH therapy before the age of 6 in the University Hospital of Occupational and Environmental Health and Kyushu Rousai Hospital...
2018: Journal of UOEH
Hiroyoshi Tanaka
In light of the cartographic Complementizer Phrase (CP) analysis, in which two computationally requisite functional projections (i.e., Force Phrase: ForceP and Finite Phrase: FinP) sandwich two optional discourse-related projections (i.e., Topic Phrase: TopP and Focus Phrase: FocP) in the clause-peripheral domain, it is theoretically reasonable to postulate the former as phase, a basic computational unit assumed in recent minimalist syntactic theory. We call this hybrid-type of syntactic analysis Phase-based CP Cartographic Analysis...
2018: Journal of UOEH
Masatoshi Kanayama, Masaaki Inoue, Junichi Yoshida, Fumihiro Tanaka
Situs inversus totalis is a rare clinical condition that represents a complete mirror image of the normal arrangement of the thoracic and abdominal viscera. There are very few reported cases of lung cancer patients with situs inversus totalis, but this condition requires particular care during surgery. A 61-year-old woman presented to our hospital with an abnormal shadow on chest radiography. Computed tomography revealed a 25×12 mm solitary pulmonary nodule in the left upper lobe (S2) and a complete mirror image of the normal organ arrangement, which findings met the criteria of situs inversus totalis...
2018: Journal of UOEH
Tomomi Ikegami, Yukiyo Yamamoto, Motohide Goto, Rinko Kawagoe, Yasusada Kawada, Koichi Kusuhara
We report here a 13-year-old female with Graves' disease, whose diagnostic clue was glycosuria, which was detected by a urine glucose screening program at school. She had had mild general malaise, and a physical examination revealed a slightly enlarged thyroid gland. Hyperthyroidism (thyroid-stimulating hormone (TSH) < 0.01 μU/ml, free triiodothyronine (fT3) 23.57 pg/ml, free thyroxine (fT4) 3.38 ng/dl) and anti-thyroid autoantibodies (TRAb 43.6%) were detected in laboratory tests, and her plasma glucose at 120 minutes was 142 mg/dl in a 75 g oral glucose tolerance test...
2018: Journal of UOEH
Yoshihisa Fujino
There has been a growing interest in presenteeism in recent years in both the occupational health and management fields. However, the term "presenteeism" was introduced in Japan relatively recently, and only limited knowledge on the subject has since been accumulated. This review will outline the current knowledge on presenteeism and discuss the significance of addressing presenteeism in occupational health in Japan. A common definition of presenteeism is the state that showing up at the office while having health problems, and some have added a decline in productivity...
2018: Journal of UOEH
Hiroyuki Morii, Takehiro Nishimura, Masahiro Takeo, Chika Katayama, Kana Nakai
Novel drugs possessing a mechanism of action specific to pathogenic mycobacteria, including Mycobacterium tuberculosis, are needed. In 2010, we discovered that the biosynthetic pathway of phosphatidylinositol, which is a membrane phospholipid, differs between humans and mycobacteria. The key enzyme responsible for this difference is phosphatidylinositol phosphate (PIP) synthase, which is present only in a few bacteria belonging to the phylum Actinobacteria. Discovering compounds that inhibit the activity of this enzyme will lead to the development of new drugs specific to pathogenic mycobacteria...
2018: Journal of UOEH
Soichi Hirashima, Akihiko Miyawaki, Kotaro Oho, Yawaka Shitozawa, Motohiro Arai, Norihiko Furuta, Ryoichi Oya
Peritoneal dialysis can be performed at home, and the transfer of solutes in the blood and other body fluids is slow compared to hemodialysis, reducing the load on the circulatory organs and lessening the frequency of hospital visits. We encountered a male patient in his 70s on peritoneal dialysis for end-stage renal failure who developed obsolete mandibular fracture-associated pseudarthrosis accompanied by osteomyelitis, which was treated with noninvasive reduction and fixation using circumferential wiring after the resolution of inflammation...
2018: Journal of UOEH
Tetsuo Takahashi, Tatsuhiko Kubo, Koji Mori
Studying the crisis management systems of other developed countries has been effective in clarifying what the position and roles of occupational health and safety functions should be in the crisis management system in Japan. In addition to previous studies on the US system, we studied the UK system. We gathered relevant information by visiting the headquarters of the Health and Safety Executive (HSE) and the Office for Nuclear Regulation (ONR), as well as obtaining information available via the internet. In the UK, the crisis management system was developed based on the Civil Contingencies Act of 2004, which regulated the system of planning and actual correspondence...
2018: Journal of UOEH
Tomoko Honda
Many mothers in the postpartum period complain of fatigue and shortened sleeping time because of child care. Breastfeeding, especially in the early postpartum period, accounts for a large share of this problem. The purpose of this study is to assess the effects of breastfeeding on the sleep of mothers in the postpartum period, using 2 questionnaires: a self-created questionnaire for a survey of breastfeeding, and the OSA sleep inventory MA version for sleeping mothers. We performed the investigation twice, at 5-8 days and at one month after childbirth...
2018: Journal of UOEH
Kazue Yoneda, Naoko Imanishi, Yoshinobu Ichiki, Fumihiro Tanaka
Cancer immunotherapy with immune checkpoint inhibitors (ICIs) has become a "game changer" in the treatment of advanced non-small cell lung cancer (NSCLC). Its most clinically important advantage over traditional chemotherapy using cytotoxic agents are its long-term survival benefits, and some advanced NSCLC patients treated with an antibody against programmed cell death 1 (PD-1) have survived for 5 years or longer. Immune checkpoint inhibitors (ICIs) are also potentially useful for earlier-stage NSCLC when used in combination with surgery or radiotherapy...
2018: Journal of UOEH
Kazuhiro Yatera, Yasuo Morimoto, Susumu Ueno, Shingo Noguchi, Takako Kawaguchi, Fumihiro Tanaka, Hideaki Suzuki, Toshiaki Higashi
Hexavalent chromium (Cr(VI)) compounds are recognized as carcinogens in the respiratory tract, giving rise to cancers of the lung, nose and nasal sinuses, especially in certain occupational environments. Inhalation exposure of Cr(VI)-containing particles, dusts and fumes commonly occurs in chromium-related occupational environments, such as chromium production, plating, welding of chromium-containing metals and alloys, electroplating, chromium-containing pigments and paints. Epidemiological surveys of chromium compounds have shown strong associations between exposure to Cr(VI) and mortality due to lung cancer, as well as positive associations with cancers of the nose and nasal cavity...
2018: Journal of UOEH
Fumi Takahashi-Yanaga
Glycogen synthase kinase-3 (GSK-3) is a cytoplasmic serine/threonine protein kinase which is known to regulate a variety of cellular processes through a number of signaling pathways important for cell proliferation, stem cell renewal, apoptosis and development. Although GSK-3 exists in a variety of tissues, this kinase plays very important roles in the heart to control its development through the formation of heart and cardiomyocyte proliferation. GSK-3 is also recognized as one of the main molecules that control cardiac hypertrophy and fibrosis...
2018: Journal of UOEH
Shun-Ichi Nihei, Hideaki Arai, Takayuki Uchida, Ayako Kanazawa, Takeru Endo, Ken Otsuji, Nobuya Harayama, Keiji Aibara, Masayuki Kamochi
A post-marketing surveillance study reported fatalities following tissue plasminogen activator administration in acute aortic dissection (AAD) with the symptoms of acute ischemic stroke (AIS) patients. Therefore, it is important to discriminate AAD from AIS. The present study aimed to investigate whether fibrinogen/fibrin degradation products (FDP) value can be useful in differential diagnosis between AAD and AIS. The study group comprised 20 AAD patients (10 men and 10 women; age 63.9 ± 13.6 years) and 159 AIS patients (91 men and 68 women; age 74...
2018: Journal of UOEH
(no author information available yet)
No abstract text is available yet for this article.
2018: Journal of UOEH
Yu Sawada, Motonobu Nakamura
Skin is an important organ that is located on the outermost layer of the human body, and serves as a defense barrier against external stimulation. Daily life style, including diet, exercise, and sleep, is a fundamental behavior of humans, and it has recently been reported that daily life style has a strong relationship with the inflammatory condition of skin diseases. This relationship has been examined by various approaches, including epidemiological investigations. Psoriasis is one inflammatory skin disease and is especially closely related with daily life style, such as diet, sleep, smoking and alcohol consumption...
2018: Journal of UOEH
Keiichi Torimoto, Yosuke Okada, Yoshiya Tanaka
Vascular endothelial function is important for maintaining the homeostasis of the living body. Especially, nitric oxide (NO) produced in vascular endothelial cells regulates blood vessel tone and has an antiatherosclerotic effect. Type 2 diabetes is a typical disease that causes impaired vascular endothelial function, resulting in various vascular complications and damage to organs. Cardiovascular disease associated with type 2 diabetes is a chronic inflammatory disease that starts with endothelial dysfunction (ED), and vascular ED is important as an initial change in arteriosclerotic lesions...
2018: Journal of UOEH
Nagisa Okada, Akinori Nakata, Masahiro Nakano, Kumiko Sakai, Kiyako Takai, Hiromi Kodama, Toshio Kobayashi
Many female nurses leave their jobs because of major life events. However, the mental health status and related factors among nurses who assume the roles of wives and/or mothers have been insufficiently examined. Therefore we examined the mental health levels and related factors among such nurse. We conducted a questionnaire survey on 763 female nurses working at general hospitals with over 200 beds in Fukuoka Prefecture. Of 402 responses, 108 were divided into two groups: nurses who had left because of marriage, childbirth, or childrearing (leaving group), and those who had not (non-leaving group)...
2018: Journal of UOEH
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