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Cycloartane triterpenoid and its glucoside isolated from Cassia occidentalis.
Chinese Journal of Natural Medicines 2017 December
In the present study, one new cycloartane triterpenoid, named cycloccidentalic acid C (1) and its glucoside, cycloccidentaliside VI (2) were isolated from the whole plant of Cassia occidentalis. Their structures were elucidated by a combinational analyses of 1D and 2D NMR data and HRMS. Compound 2 showed modest anti-HIV-1 activity with EC50 value of 1.44 μmol·L-1 and TI (Therapeutic Index) value of 15.59.
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