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Journal Article
A novel role for renal epithelial cells and the medullary sodium gradient in the local immune response.
Kidney International 2017 December
The extreme hypertonicity of the renal medulla plays a central role in regulating volume status. A recent publication in Cell has identified a novel role for the high sodium environment and the local epithelial cells in the recruitment of mononuclear phagocytes, potentially contributing to the defense against ascending urinary tract infection.
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